Published in J Neurosci Res on April 15, 2001
Molecular mechanisms of necrosis in glioblastoma: the role of glutamate excitotoxicity. Cancer Biol Ther (2009) 1.10
Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression. J Neurosci (2011) 0.95
Glutamate transporters in brain ischemia: to modulate or not? Acta Pharmacol Sin (2014) 0.75
Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol (1991) 14.25
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci (2000) 9.85
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science (2000) 6.28
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci U S A (1999) 5.75
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron (1995) 4.78
FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) (1987) 4.54
Functional expression of a mammalian odorant receptor. Science (1998) 4.09
Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature (1994) 3.87
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med (2001) 3.84
The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity. Neurology (1990) 3.79
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci U S A (1993) 3.73
On the suture of separate nerve bundles in a nerve trunk and on internal nerve plexuses. J Physiol (1917) 3.72
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proc Natl Acad Sci U S A (1998) 3.54
Massive Dirac fermion on the surface of a magnetically doped topological insulator. Science (2010) 3.46
Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol (1997) 3.38
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology (2001) 3.30
Collagen degradation by host-derived enzymes during aging. J Dent Res (2004) 3.30
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. Invest Ophthalmol Vis Sci (1999) 2.89
The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Mol Cell Biol (2001) 2.87
DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology (2007) 2.86
Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proc Natl Acad Sci U S A (1993) 2.79
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J Neurosci (1996) 2.69
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology (1998) 2.67
Genetic evidence for the involvement of tau in progressive supranuclear palsy. Ann Neurol (1997) 2.60
Neurocognitive dysfunction predicts postmortem findings of HIV encephalitis. Neurology (2002) 2.47
Pharmacokinetics of a novel quinolone, AT-4140, in animals. Antimicrob Agents Chemother (1990) 2.42
beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci U S A (2001) 2.40
Distribution of brain HIV load in AIDS. Brain Pathol (1998) 2.36
alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol (2000) 2.36
Diffuse plaques do not accentuate synapse loss in Alzheimer's disease. Am J Pathol (1990) 2.24
Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders. Am J Pathol (1998) 2.19
Pulmonary arteriovenous malformations: cerebral ischemia and neurologic manifestations. Neurology (2000) 2.18
Neocortical damage during HIV infection. Ann Neurol (1991) 2.15
beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor. Neuron (2001) 2.05
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42). J Neurosci Res (2001) 2.04
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease. Nature (1997) 1.99
Internet-based program for automatic discrimination of dermoscopic images between melanomas and Clark naevi. Br J Dermatol (2004) 1.99
Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection. Hepatology (1994) 1.96
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease. J Biol Chem (1995) 1.95
Unusual widening of Virchow-Robin spaces: MR appearance. AJNR Am J Neuroradiol (1995) 1.92
The roles of the C-terminal domain and type III domains of chitinase A1 from Bacillus circulans WL-12 in chitin degradation. J Bacteriol (1994) 1.91
Clinical-neuropathological correlations in Alzheimer's disease and related dementias. Arch Neurol (1994) 1.90
Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center. Brain Pathol (1999) 1.89
From a single-band metal to a high-temperature superconductor via two thermal phase transitions. Science (2011) 1.87
Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J Immunol (1998) 1.87
The National NeuroAIDS Tissue Consortium: a new paradigm in brain banking with an emphasis on infectious disease. Neuropathol Appl Neurobiol (2001) 1.86
Changing patterns in the neuropathogenesis of HIV during the HAART era. Brain Pathol (2003) 1.81
Synaptic and neuritic alterations during the progression of Alzheimer's disease. Neurosci Lett (1994) 1.81
Analysis of result variability from high-density oligonucleotide arrays comparing same-species and cross-species hybridizations. Biotechniques (2002) 1.80
Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. Biophys J (2000) 1.79
Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy. J Neurovirol (2009) 1.75
Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Ann Neurol (2001) 1.75
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology (2004) 1.74
Observations on the atrophy of denervated muscle. J Physiol (1918) 1.74
High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain. Nat Biotechnol (2001) 1.72
Distribution of obstructive intimal lesions and their cellular phenotypes in chronic pulmonary hypertension. A morphometric and immunohistochemical study. Am J Respir Crit Care Med (2000) 1.71
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology (1974) 1.70
Neurodegeneration in the central nervous system of apoE-deficient mice. Exp Neurol (1995) 1.66
Multiple cytokine activities and loss of interleukin 2 inhibitor in synovial fluids of patients with rheumatoid arthritis. J Rheumatol (1988) 1.63
Synthesis of oligothymidylates and nucleoside cyclic phosphates by oxidation-reduction condensation. J Am Chem Soc (1972) 1.63
Characterization of a gene responsible for the Na+/H+ antiporter system of alkalophilic Bacillus species strain C-125. Mol Microbiol (1994) 1.63
A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J Neurochem (1994) 1.62
Hyperbaric oxygen reduces infarct volume in rats by increasing oxygen supply to the ischemic periphery. Crit Care Med (2000) 1.62
Quantitative synaptic alterations in the human neocortex during normal aging. Neurology (1993) 1.61
Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology (1997) 1.58
Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice. Brain Res (1994) 1.58
Cholinergic dysfunction in diseases with Lewy bodies. Neurology (2000) 1.58
Neurochemical markers do not correlate with cognitive decline in the Lewy body variant of Alzheimer disease. Arch Neurol (1999) 1.56
Cerebral glucose metabolism in patients with frontotemporal dementia. J Nucl Med (1998) 1.55
Normal variations of the temporal bone on high-resolution CT: their incidence and clinical significance. Clin Radiol (1995) 1.55
Borna disease virus in human brains with a rare form of hippocampal degeneration but not in brains of patients with common neuropsychiatric disorders. J Infect Dis (1999) 1.53
Laparoscopic cholecystectomy for a suspected case of gallbladder carcinoma. Am J Gastroenterol (1991) 1.52
Measurement of airborne mite allergen exposure in individual subjects. J Allergy Clin Immunol (1996) 1.52
A genome-wide functional assay of signal transduction in living mammalian cells. Nat Biotechnol (1998) 1.51
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin. J Neurosci Res (2008) 1.50
Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma. J Gastroenterol Hepatol (1999) 1.50
Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol (1996) 1.50
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro. Neuroreport (1999) 1.49
Creation and control of a two-dimensional electron liquid at the bare SrTiO3 surface. Nat Mater (2011) 1.49
Clinical aspects of intrahepatic bile duct carcinoma including hilar carcinoma: a study of 57 autopsy-proven cases. Cancer (1977) 1.49
Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1. Am J Pathol (1995) 1.47
Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc Natl Acad Sci U S A (1997) 1.46
Immunoreactive circulating alpha-interferon is low in Sjögren's syndrome. Br J Rheumatol (1990) 1.45