Published in J Am Soc Nephrol on May 01, 2001
Sirolimus Conversions in African-American Renal Transplant Recipients | NCT01005706
Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts. J Am Soc Nephrol (2009) 1.69
Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice. J Clin Invest (2012) 1.14
Rapamycin retards growth and causes marked alterations in the growth plate of young rats. Pediatr Nephrol (2007) 0.99
Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation. Bone Marrow Transplant (2011) 0.98
Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors. Br J Pharmacol (2004) 0.93
Sirolimus and post transplant Cy synergistically maintain mixed chimerism in a mismatched murine model. Bone Marrow Transplant (2013) 0.91
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. Chem Res Toxicol (2009) 0.90
Association of immunosuppressant-induced protein changes in the rat kidney with changes in urine metabolite patterns: a proteo-metabonomic study. J Proteome Res (2010) 0.90
Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs. Biomaterials (2014) 0.83
Co-delivery of doxorubicin and curcumin by pH-sensitive prodrug nanoparticle for combination therapy of cancer. Sci Rep (2016) 0.82
Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat. PLoS One (2012) 0.81
Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells. J Transplant (2012) 0.80
Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria. Br J Pharmacol (2003) 0.79
The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients. Eur J Clin Pharmacol (2009) 0.78
Stable renal function after islet transplantation: importance of patient selection and aggressive clinical management. Transplantation (2009) 0.78
Everolimus in acute kidney injury in a patient with breast cancer: a case report. J Med Case Rep (2014) 0.78
Transplantation: sirolimus plus calcineurin inhibitors in transplantation. Nat Rev Nephrol (2009) 0.75
Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results. Int J Nanomedicine (2006) 0.75
Reviewing 15 years of experience with sirolimus. Transplant Res (2015) 0.75
Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney. Br J Pharmacol (2005) 0.75
Mycophenolate mofetil enhances the negative effects of sirolimus and tacrolimus on rat kidney cell metabolism. PLoS One (2014) 0.75
Sirolimus rescue of renal failure in children after combined liver-kidney transplantation. Pediatr Nephrol (2005) 0.75
Sirolimus monotherapy versus sirolimus in combination with steroids and/or MMF for immunosuppression after liver transplantation. Dig Dis Sci (2006) 0.75
The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res (2004) 54.37
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul (1984) 35.22
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med (2000) 7.48
THE STANDARDIZATION OF ANTIPNEUMOCOCCIC SERUM TYPES I AND II. J Exp Med (1930) 5.18
Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene (2007) 4.81
Interactive memory systems in the human brain. Nature (2001) 4.53
A mathematical evaluation of the core conductor model. Biophys J (1966) 4.41
The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci (2001) 4.33
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell (2001) 4.25
Health-related quality of life in patients served by the Department of Veterans Affairs: results from the Veterans Health Study. Arch Intern Med (1998) 4.07
Recovering meaning: left prefrontal cortex guides controlled semantic retrieval. Neuron (2001) 3.92
Campylobacter pyloridis in peptic ulcer disease: microbiology, pathology, and scanning electron microscopy. Gut (1985) 3.48
Prevalence of insomnia symptoms in patients with sleep-disordered breathing. Chest (2001) 3.37
The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation. J Biol Chem (1997) 3.16
Fos expression in orexin neurons varies with behavioral state. J Neurosci (2001) 3.08
A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities. Arch Gen Psychiatry (2000) 3.06
Generalized equations for the analysis of inhibitions of Michaelis-Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors. Eur J Biochem (1981) 3.01
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes (1998) 2.94
Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci (2001) 2.79
Interactions of mast cell tryptase with thrombin receptors and PAR-2. J Biol Chem (1997) 2.79
Control of organ asymmetry in flowers of Antirrhinum. Cell (1999) 2.74
Induction of immune responses in vivo with small numbers of veiled (dendritic) cells. Proc Natl Acad Sci U S A (1983) 2.68
BI-RG-587 is active against zidovudine-resistant human immunodeficiency virus type 1 and synergistic with zidovudine. Antimicrob Agents Chemother (1991) 2.66
Human colonic adenocarcinoma cells. I. Establishment and description of a new line. In Vitro (1976) 2.65
The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statement. Eur Respir J (2010) 2.56
The impact of comorbid and sociodemographic factors on access to renal transplantation. JAMA (1993) 2.54
Ribavirin antagonizes the effect of azidothymidine on HIV replication. Science (1987) 2.51
Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon. Antimicrob Agents Chemother (1987) 2.47
The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene. Hum Mol Genet (1996) 2.45
Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. Br J Cancer (2010) 2.45
Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands. J Theor Biol (1976) 2.42
Lead and hyperactivity. Lancet (1972) 2.42
Human midbrain sensitivity to cognitive feedback and uncertainty during classification learning. J Neurophysiol (2004) 2.41
Health status in VA patients: results from the Veterans Health Study. Am J Med Qual (1999) 2.35
A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems. J Biol Chem (1977) 2.32
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem (1992) 2.31
The extracellular potential field of the single active nerve fiber in a volume conductor. Biophys J (1968) 2.31
Clinical features, aetiology and outcome of empyema in children in the north east of England. Thorax (2004) 2.31
Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol (2001) 2.30
Mid-Pleistocene Acheulean-like stone technology of the Bose basin, South China. Science (2000) 2.28
Early and delayed shut-off of host protein synthesis in cells infected with herpes simplex virus. J Gen Virol (1982) 2.22
Salt extraction of soluble HL-A antigens. Science (1971) 2.18
Mortality among injecting drug users: a critical reappraisal. J Epidemiol Community Health (1993) 2.17
MRI findings in Susac's syndrome. Neurology (2003) 2.17
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. EMBO J (1995) 2.14
Expression of a dominant allele of human ARF1 inhibits membrane traffic in vivo. J Cell Biol (1994) 2.11
Nursing: an intellectual activity. BMJ (1991) 2.03
Why nursing education has to change. Br Med J (Clin Res Ed) (1986) 2.01
Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial. J Urol (2001) 1.96
Two-drug combinations of zidovudine, didanosine, and recombinant interferon-alpha A inhibit replication of zidovudine-resistant human immunodeficiency virus type 1 synergistically in vitro. J Infect Dis (1991) 1.93
From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim Biophys Acta (1993) 1.89
Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. J Biol Chem (1991) 1.89
Benign melanocytic naevi as a risk factor for malignant melanoma. Br Med J (Clin Res Ed) (1986) 1.88
Synergistic neutralization of HIV-1 by human monoclonal antibodies against the V3 loop and the CD4-binding site of gp120. AIDS Res Hum Retroviruses (1992) 1.85
Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters. Transplantation (1985) 1.83
Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health chronic prostatitis symptom index. J Urol (2001) 1.82
Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma. J Clin Oncol (1999) 1.81
Validation of a western immunoblotting procedure for bovine PrP(Sc) detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE). Acta Neuropathol (1999) 1.76
Home antibiotic therapy for low-risk cancer patients with fever and neutropenia: a pilot study of 30 patients based on a validated prediction rule. J Clin Oncol (1994) 1.75
Unusual electrocardiographic manifestation of pulmonary embolism. Am Heart J (1970) 1.74
Transplantation antigens. Adv Immunol (1970) 1.70
Human T-cell leukaemia/lymphoma virus-associated lymphoreticular neoplasia in Jamaica. Lancet (1983) 1.69
Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart. FASEB J (2001) 1.68
Nephrotic syndrome associated with Kimura disease. Pediatr Nephrol (2000) 1.63
Clinical assessment of the probability of coronary artery disease: judgmental bias from personal knowledge. Med Decis Making (1992) 1.63
Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. J Neurosci (2001) 1.62
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst (1998) 1.60
Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor. Dev Biol (2001) 1.59
Laparoscopic vs open appendectomy. Prospective randomized study of outcomes. Arch Surg (1997) 1.57
Comparing preincisional with postincisional bupivacaine infiltration in the management of postoperative pain. Arch Surg (1997) 1.57
Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene. Oncogene (1990) 1.56
Integrated record keeping as an essential aspect of a primary care led health service. BMJ (1998) 1.55
En bloc transplantation of kidneys from pediatric donors. J Urol (1996) 1.51
Synergistic inhibition of human T-cell lymphotropic virus type III replication in vitro by phosphonoformate and recombinant alpha-A interferon. Antimicrob Agents Chemother (1986) 1.51
Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients. Proc Natl Acad Sci U S A (1986) 1.51
Vasodilator pre-treatment of human radial arteries; comparison of effects of phenoxybenzamine vs papaverine on norepinephrine-induced contraction in vitro. Eur Heart J (2001) 1.47
The synergistic effects of cyclosporine and sirolimus. Transplantation (1997) 1.47
The British National Health Service 1948-1978: should we start again? J Adv Nurs (1979) 1.47
Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer. Br J Cancer (2005) 1.46
The potential role of custody facilities in controlling sexually transmitted diseases. Am J Public Health (1992) 1.44
Patient noncompliance: a major cause of late graft failure in cyclosporine-treated renal transplants. Transplant Proc (1988) 1.44
Ranitidine, cimetidine, and the cyclosporine-treated recipient. Transplantation (1986) 1.44
The binding of colchicine by sarcoma 180 cells. Biochem Pharmacol (1968) 1.43
Pharmacokinetics of sirolimus in stable renal transplant patients after multiple oral dose administration. J Clin Pharmacol (1997) 1.43
A method of estimating curare-like activity on the isolated phrenic nerve diaphragm preparation of the rat. Br J Pharmacol Chemother (1947) 1.42
Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids. Ophthalmology (1990) 1.42
An upper limit on the stochastic gravitational-wave background of cosmological origin. Nature (2009) 1.42
Population pharmacokinetics and exposure-response relationships for basiliximab in kidney transplantation. The U.S. Simulect Renal Transplant Study Group. Transplantation (1999) 1.42
Bacteriophage and associated polysaccharide depolymerases--novel tools for study of bacterial biofilms. J Appl Microbiol (1998) 1.41
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives. J Med Chem (1993) 1.41
Detection of thirty-second cognitive activations in single subjects with positron emission tomography: a new low-dose H2(15)O regional cerebral blood flow three-dimensional imaging technique. J Cereb Blood Flow Metab (1993) 1.41
Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100. J Acquir Immune Defic Syndr (2000) 1.41
Fluorescent lights, ultraviolet lamps, and risk of cutaneous melanoma. BMJ (1988) 1.41
The results of modified use of chemotherapy for patients with metastatic breast cancer. Eur J Cancer (1994) 1.40
HLA matching assessed from early graft function. Transplant Proc (1987) 1.40
Transoesophageal echocardiography during surgery for intra-atrial masses. Anaesthesia (2003) 1.40
Are platelet cytosolic free calcium, serotonin concentration and blood viscosity different between hypertensive and normotensive subjects? Cardiology (1994) 1.40
Direct detection of 8-oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues. Anal Biochem (1998) 1.40