A Abbruzzese

Author PubWeight™ 61.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Familial papillary thyroid microcarcinoma: a new clinical entity. Lancet 1999 1.98
2 Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization. J Biol Chem 1986 1.44
3 The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: review article. Amino Acids 2004 1.44
4 The role of eukaryotic initiation factor 5A in the control of cell proliferation and apoptosis. Amino Acids 2001 1.26
5 Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro. Br J Cancer 2003 1.21
6 Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. Cell Death Dis 2011 1.18
7 Oxidative stress and ERK1/2 phosphorylation as predictors of outcome in hepatocellular carcinoma patients treated with sorafenib plus octreotide LAR. Cell Death Dis 2011 1.14
8 Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor. Cell Death Differ 1999 1.13
9 Percutaneous aspiration biopsy of the pancreas under ultrasonic guidance. N Engl J Med 1975 1.12
10 Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways. Curr Cancer Drug Targets 2009 1.10
11 eIF5A isoforms and cancer: two brothers for two functions? Amino Acids 2011 1.09
12 The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells. J Biochem 2003 1.09
13 WNT pathway in oral cancer: epigenetic inactivation of WNT-inhibitors. Oncol Rep 2010 1.09
14 BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy. Cell Death Dis 2012 1.05
15 Percutaneous ethanol injection efficacy in the treatment of large symptomatic thyroid cystic nodules: ten-year follow-up of a large series. Thyroid 2002 1.04
16 Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications. Curr Drug Targets 2005 1.03
17 C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A. Cell Death Differ 2007 1.01
18 Current approaches and perspectives in the therapy of medullary thyroid carcinoma. Cancer 2001 0.97
19 Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A). Protein Eng 2001 0.97
20 Cetuximab ± chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro. Int J Cancer 2011 0.97
21 Self-assembly nanoparticles for the delivery of bisphosphonates into tumors. Int J Pharm 2010 0.97
22 Pamidronate improves the quality of life and induces clinical remission of bone metastases in patients with thyroid cancer. Br J Cancer 2001 0.94
23 Interferon alpha2 recombinant and epidermal growth factor modulate proliferation and hypusine synthesis in human epidermoid cancer KB cells. Biochem J 1997 0.93
24 Slow release lanreotide in combination with interferon-alpha2b in the treatment of symptomatic advanced medullary thyroid carcinoma. J Clin Endocrinol Metab 2000 0.93
25 Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study. J Cell Mol Med 2012 0.92
26 Nanotech revolution for the anti-cancer drug delivery through blood-brain barrier. Curr Cancer Drug Targets 2012 0.91
27 EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells. Cell Death Differ 2003 0.89
28 Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation. Eur J Biochem 2000 0.89
29 Cutting the limits of aminobisphosphonates: new strategies for the potentiation of their anti-tumour effects. Curr Cancer Drug Targets 2009 0.87
30 Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells. Br J Haematol 1998 0.86
31 Denosumab: the era of targeted therapies in bone metastatic diseases. Curr Cancer Drug Targets 2009 0.86
32 Docetaxel induces p53-dependent apoptosis and synergizes with farnesyl transferase inhibitor r115777 in human epithelial cancer cells. Front Biosci 2005 0.84
33 Challenging the current approaches to multiple myeloma-related bone disease: from bisphosphonates to target therapy. Curr Cancer Drug Targets 2009 0.83
34 Possible antioxidant role of SPA therapy with chlorine-sulphur-bicarbonate mineral water. Amino Acids 2008 0.83
35 Rheumatoid arthritis and the xylose tolerance test. Am J Gastroenterol 1969 0.83
36 Theophylline administration markedly reduces hepatic and pulmonary implantation of B16-F10 melanoma cells in mice. Melanoma Res 2000 0.83
37 Post-translational modifications of eukaryotic initiation factor-5A (eIF-5A) as a new target for anti-cancer therapy. Adv Exp Med Biol 1999 0.82
38 Differences in the post-translational modification of proteins by polyamines between weakly and highly metastatic B16 melanoma cells. Int J Cancer 1993 0.82
39 Differential expression and cytoplasm/membrane distribution of endoglin (CD105) in human tumour cell lines: Implications in the modulation of cell proliferation. Int J Oncol 2005 0.82
40 Translational and post-translational modifications of proteins as a new mechanism of action of alpha-interferon: review article. Amino Acids 2004 0.81
41 High-performance liquid chromatographic method for determination of hypusine and deoxyhypusine. Anal Biochem 1990 0.81
42 Post-translational formation of hypusine: biogenesis of translation initiation factor eIF-4D. Adv Exp Med Biol 1988 0.81
43 Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells. Cell Death Dis 2012 0.81
44 Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells. J Interferon Cytokine Res 2007 0.81
45 Tissue transglutaminase expression affects hypusine metabolism in BALB/c 3T3 cells. FEBS Lett 1998 0.81
46 Protein-polyamine conjugation by transglutaminase in cancer cell differentiation: review article. Amino Acids 2004 0.81
47 Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation. Melanoma Res 1998 0.80
48 γ-Tocopherol inhibits human prostate cancer cell proliferation by up-regulation of transglutaminase 2 and down-regulation of cyclins. Amino Acids 2012 0.80
49 Marked elevations of serum glutamic oxalacetic transaminase and lactic dehydrogenase activity in chronic extraheptic biliary disease. Am J Dig Dis 1969 0.80
50 A novel biweekly multidrug regimen of gemcitabine, oxaliplatin, 5-fluorouracil (5-FU), and folinic acid (FA) in pretreated patients with advanced colorectal carcinoma. Br J Cancer 2004 0.79
51 Bovine serum amine oxidase and spm potentiate docetaxel and interferon-alpha effects in inducing apoptosis on human cancer cells through the generation of oxidative stress. Biochim Biophys Acta 2008 0.79
52 Mediastinal images resembling thymus following 131-I treatment for thyroid cancer. Monaldi Arch Chest Dis 2005 0.78
53 Indirect assays for deoxyhypusine hydroxylase using dual-label ratio changes and oxidative release of radioactivity. Anal Biochem 1986 0.78
54 Biosynthesis of hypusine in eIF-4D precursors. Adv Exp Med Biol 1988 0.78
55 Automated chromatographic analysis of human placenta polyamines.. Biochem Med 1978 0.78
56 Choroid plexus carcinoma: a new case associated with a novel TP53 germ line mutation. Neuropathol Appl Neurobiol 2008 0.78
57 Identification of a substrate site for transglutaminases on the human protein synthesis initiation factor 5A. Biochem J 1995 0.78
58 Structural organization of the human eukaryotic initiation factor 5A precursor and its site-directed variant Lys50-->Arg. Amino Acids 1999 0.77
59 Role of the FAD-dependent polyamine oxidase in the selective formation of N(1),N(8)-bis(gamma-glutamyl)spermidine protein cross-links(1). Biochem Soc Trans 2007 0.77
60 Alternative therapy of earth elements increases the chondroprotective effects of chondroitin sulfate in mice. Exp Mol Med 2005 0.77
61 Prenatal diagnosis of periventricular hemorrhage by fetal brain magnetic resonance imaging. Childs Nerv Syst 1998 0.77
62 Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP. FEBS Lett 1999 0.77
63 The role of somatostatin receptors in the medical treatment of acromegaly. Dig Liver Dis 2004 0.77
64 Percutaneous ethanol injection of autonomous thyroid nodules with a volume larger than 40 ml: three years of follow-up. Clin Radiol 2001 0.77
65 Evaluation of the efficacy of potential antineoplastic drugs on tumour metastasis by a computer-assisted image analysis. Eur J Cancer 2000 0.77
66 Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution. Amino Acids 2007 0.76
67 Anticancer drugs and hyperthermia enhance cytotoxicity induced by polyamine enzymatic oxidation products. Amino Acids 2007 0.76
68 Impairment of the metastatic activity of melanoma cells by transglutaminase-catalyzed incorporation of polyamines into laminin and Matrigel. Amino Acids 2007 0.75
69 8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor. Br J Cancer 1999 0.75
70 Catalytic properties of deoxyhypusine hydroxylase. Ital J Biochem 1990 0.75
71 Post-translational modification of protein by polyamines in murine melanoma cells. Ital J Biochem 1990 0.75
72 Occurrence of 5'-deoxy-5'-methylthioadenosine phosphorylase in the mammalian CNS: distribution and kinetic studies on the rat brain enzyme. J Neurochem 1983 0.75
73 [Clinical significance of polyamine measurement in laryngeal tumors]. Ann Laringol Otol Rinol Faringol 1978 0.75
74 Unusual exophytic subependymoma in the bulbo-cerebellar angle. Case report. J Neurosurg Sci 2007 0.75
75 Regional pattern and heat-resistance of brain 5'-deoxy-5'-methylthioadenosine phosphorylase. Experientia 1986 0.75