PubRank

D W Hay

Author PubWeight™ 66.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 1999 3.20
2 Variation in river water temperatures in an upland stream over a 30-year period. Sci Total Environ 2001 2.03
3 SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol 2000 1.75
4 The effects of epithelium removal on the sensitivity of guinea-pig isolated trachealis to bronchodilator drugs. Br J Pharmacol 1986 1.50
5 Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. Mol Pharmacol 1999 1.47
6 SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J Pharmacol Exp Ther 2000 1.37
7 Airway epithelium modulates the reactivity of guinea-pig respiratory smooth muscle. Eur J Pharmacol 1986 1.35
8 Spawning success in Atlantic salmon (Salmo salar L.): a long-term DNA profiling-based study conducted in a natural stream. Mol Ecol 2001 1.28
9 Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. Am J Respir Cell Mol Biol 1998 1.25
10 Epithelium removal increases the reactivity of human isolated tracheal muscle to methacholine and reduces the effect of verapamil. Eur J Pharmacol 1986 1.17
11 Demonstration of the release of an epithelium-derived inhibitory factor from a novel preparation of guinea-pig trachea. Eur J Pharmacol 1987 1.16
12 Relaxation of guinea-pig tracheal smooth muscle to arachidonate is converted to contraction following epithelium removal. Br J Pharmacol 1987 1.11
13 Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. J Pharmacol Exp Ther 1994 1.10
14 Endothelin-1 receptor density, distribution, and function in human isolated asthmatic airways. Am J Respir Crit Care Med 1995 1.07
15 Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle. J Pharmacol Exp Ther 1993 1.06
16 Epithelium modulates the reactivity of ovalbumin-sensitized guinea-pig airway smooth muscle. Life Sci 1986 1.06
17 Airway epithelium-derived inhibitory factor. Trends Pharmacol Sci 1990 1.05
18 Cellular mechanisms of endothelin in rabbit aorta. J Pharmacol Exp Ther 1989 1.05
19 Effects of some organic calcium antagonists and other procedures affecting Ca2+ Translocation on KCl-induced contractions in the rat vas deferens. Br J Pharmacol 1982 1.04
20 Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate. Am J Respir Cell Mol Biol 2000 1.02
21 Local anaesthetic activity of organic calcium antagonists: relevance to their actions on smooth muscle. Eur J Pharmacol 1982 1.01
22 Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist. J Pharmacol Exp Ther 2000 1.00
23 The effect of verapamil is reduced in isolated airway smooth muscle preparations lacking the epithelium. Life Sci 1986 0.99
24 Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations. Genes Immun 2007 0.99
25 Endothelin-1-induced potentiation of human airway smooth muscle proliferation: an ETA receptor-mediated phenomenon. Br J Pharmacol 1996 0.97
26 Receptors for endothelin-1 in asthmatic human peripheral lung. Br J Pharmacol 1995 0.96
27 Expression and function of voltage-dependent potassium channel genes in human airway smooth muscle. J Biol Chem 1996 0.94
28 Endothelin B receptor modulates inflammatory pain and cutaneous inflammation. Mol Pharmacol 1999 0.93
29 Involvement of cysteinyl leukotrienes in airway smooth muscle cell DNA synthesis after repeated allergen exposure in sensitized Brown Norway rats. Br J Pharmacol 1999 0.93
30 The antitussive activity of delta-opioid receptor stimulation in guinea pigs. J Pharmacol Exp Ther 2000 0.92
31 Antiasthmatic activity of the second-generation phosphodiesterase 4 (PDE4) inhibitor SB 207499 (Ariflo) in the guinea pig. J Pharmacol Exp Ther 1998 0.88
32 Effects of KCl on 45Ca uptake and efflux in the rat vas deferens. Br J Pharmacol 1984 0.88
33 Is the guinea pig trachea a good in vitro model of human large and central airways? Comparison on leukotriene-, methacholine-, histamine- and antigen-induced contractions. J Pharmacol Exp Ther 1987 0.88
34 Nonpeptide endothelin receptor antagonists. XI. Pharmacological characterization of SB 234551, a high-affinity and selective nonpeptide ETA receptor antagonist. J Pharmacol Exp Ther 1998 0.86
35 Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody. Am J Respir Crit Care Med 1996 0.86
36 Effect of verapamil on rhythmic contractions in isolated rat vasa deferentia [proceedings]. Br J Pharmacol 1980 0.85
37 Effects of intranasal administration of endothelin-1 to allergic and nonallergic individuals. Am J Respir Crit Care Med 1995 0.84
38 The effects of calcium channel inhibitors and other procedures affecting calcium translocation on drug-induced rhythmic contractions in the rat vas deferens. Br J Pharmacol 1983 0.84
39 Phosphodiesterase IV inhibitors as therapy for eosinophil-induced lung injury in asthma. Environ Health Perspect 1994 0.84
40 The development of tone in the smooth muscle of guinea-pig isolated tracheal preparations may be influenced by prostanoids released from the adjacent airway cartilage. Prostaglandins 1987 0.83
41 Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. J Pharmacol Exp Ther 1997 0.83
42 Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist. J Pharmacol Exp Ther 1996 0.82
43 The effects of calcium channel inhibitors on twitches and noradrenaline contractions of the rat bisected vas deferens. Eur J Pharmacol 1983 0.82
44 Role of neurokinin receptors in the behavioral effect of intravesical antigen infusion in guinea pig bladder. J Urol 2000 0.82
45 In vitro and in vivo characterization of NK3 receptors in the rabbit eye by use of selective non-peptide NK3 receptor antagonists. Br J Pharmacol 1997 0.81
46 The contractile effects of 5-hydroxytryptamine on the rat isolated vas deferens. Br J Pharmacol 1982 0.81
47 Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia. Br J Pharmacol 1992 0.81
48 Differences in time-related cardiopulmonary responses to hypoxia in three rat strains. Clin Exp Hypertens 2000 0.80
49 2-Phenyl-4-quinolinecarboxamides: a novel class of potent and selective non-peptide competitive antagonists for the human neurokinin-3 receptor. J Med Chem 1996 0.80
50 Nonpeptide endothelin receptor antagonists. X. Inhibition of endothelin-1- and hypoxia-induced pulmonary pressor responses in the guinea pig by the endothelin receptor antagonist, SB 217242. J Pharmacol Exp Ther 1997 0.79
51 Nonpeptide endothelin receptor antagonists. VIII: attentuation of acute hypoxia-induced pulmonary hypertension in the dog. J Pharmacol Exp Ther 1997 0.79
52 Targeted disruption of the endothelin-B-receptor gene attenuates inflammatory nociception and cutaneous inflammation in mice. J Cardiovasc Pharmacol 2000 0.79
53 Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor. Eur J Pharmacol 2001 0.79
54 Subcellular localization of leukotriene D4 receptors in sheep tracheal smooth muscle. Mol Pharmacol 1988 0.79
55 Food restriction-mediated adrenal influences on antigen-induced bronchoconstriction and airway eosinophil influx in the guinea pig. Int Arch Allergy Immunol 1998 0.79
56 Chronic hypoxia-induced cardiopulmonary changes in three rat strains: inhibition by the endothelin receptor antagonist SB 217242. J Cardiovasc Pharmacol 1998 0.79
57 Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 1. Identification of the 4-quinolinecarboxamide framework. J Med Chem 1997 0.78
58 Influence of cartilage on reactivity and on the effectiveness of verapamil in guinea pig isolated airway smooth muscle. J Pharmacol Exp Ther 1987 0.78
59 The endothelins in the pulmonary system. Pulm Pharmacol 1996 0.78
60 The dependence of airway smooth muscle on extracellular Ca2+ for contraction is influenced by the presence of cartilage. Life Sci 1986 0.78
61 Differential antagonism of airway contractile responses to prostaglandin (PG)D2 and 9 alpha, 11 beta-PGF2 by atropine, SK&F 88046 and SQ 29,548 in the guinea pig. J Pharmacol Exp Ther 1994 0.78
62 Characterization of NK3 receptors in rabbit isolated iris sphincter muscle. Br J Pharmacol 1997 0.78
63 Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity and selectivity in quinoline tachykinin receptor antagonists. J Med Chem 2001 0.78
64 Differences in the ability of salbutamol to prevent and reverse LTC4-induced contractions of the guinea-pig isolated trachea: influence of l-serine borate. Eur J Pharmacol 1986 0.77
65 SK&F 104353, a selective leukotriene receptor antagonist, inhibits leukotriene D4- and antigen-induced bronchoconstriction in cynomolgus monkeys. Pulm Pharmacol 1992 0.77
66 An overview of species differences in the effects of a water extract of cotton bract on isolated airway smooth muscle, and effects of E. coli lipopolysaccharide. Environ Health Perspect 1986 0.76
67 Evidence that the proposed novel human "neurokinin-4" receptor is pharmacologically similar to the human neurokinin-3 receptor but is not of human origin. Mol Pharmacol 2000 0.76
68 Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412). J Med Chem 1999 0.76
69 Effect of SB 217242 on hypoxia-induced cardiopulmonary changes in the high altitude-sensitive rat. Pulm Pharmacol Ther 1999 0.76
70 Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models of allergic asthma. J Pharmacol Exp Ther 1995 0.76
71 Temporal and spatial patterns of sea lice levels on sea trout in western Scotland in relation to fish farm production cycles. Biol Lett 2010 0.75
72 The preclinical and clinical pharmacology of SK&F 104353, a potent and selective peptidoleukotriene receptor antagonist. Ann N Y Acad Sci 1991 0.75
73 The bronchopulmonary pharmacology of SK&F 104353 in anesthetized guinea pigs: demonstration of potent and selective antagonism of responses to peptidoleukotrienes. J Pharmacol Exp Ther 1989 0.75
74 The effect of inhibitors of prostaglandin formation on contraction of the rat, rabbit and human vas deferens. J Auton Pharmacol 1990 0.75
75 Cysteinyl leukotriene receptor assays. Curr Protoc Pharmacol 2001 0.75
76 Role of phosphatidylinositol turnover in the contraction of the rat aorta. Adv Exp Med Biol 1991 0.75
77 In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity. Prostaglandins Leukot Essent Fatty Acids 1999 0.75
78 Replacement of the quinoline system in 2-phenyl-4-quinolinecarboxamide NK-3 receptor antagonists. Farmaco 1999 0.75
79 Calcium uptake into guinea-pig trachealis: the effect of epithelium removal. Cell Calcium 1987 0.75
80 Pharmacologic profile of SK&F 104353, a novel, highly potent and selective peptidoleukotriene antagonist. Adv Prostaglandin Thromboxane Leukot Res 1987 0.75
81 Sensitivity changes in the smooth muscle of the guinea-pig isolated vas deferens after treatment of animals with 6-hydroxydopamine. J Pharmacol Exp Ther 1985 0.75
82 Hypoxia-induced pulmonary hypertension in an optimized environment for the guineapig. Lab Anim 1997 0.75
83 KCl contractions in the rat intact and bisected vas deferens: contribution of endogenous noradrenaline release. Clin Exp Pharmacol Physiol 1983 0.75