Published in Endocrinology on June 01, 2001
Nuclear Receptors, RXR, and the Big Bang. Cell (2014) 2.22
Epigenetic control of female puberty. Nat Neurosci (2013) 1.34
Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis. J Clin Invest (2007) 1.15
Gene networks and the neuroendocrine regulation of puberty. Mol Cell Endocrinol (2009) 1.06
Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice. J Clin Invest (2008) 0.99
The transcriptional control of female puberty. Brain Res (2010) 0.90
Development of gonadotropin-releasing hormone secretion and pituitary response. J Neurosci (2014) 0.89
A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates. Horm Behav (2013) 0.80
Lower sperm DNA fragmentation after r-FSH administration in functional hypogonadotropic hypogonadism. J Assist Reprod Genet (2013) 0.75
Hypogonadotropic hypogonadism presenting with arhinia: a case report. J Med Case Rep (2013) 0.75
The mystery of puberty initiation: genetics and epigenetics of idiopathic central precocious puberty (ICPP). J Endocrinol Invest (2017) 0.75
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology (2004) 4.24
The economic impact of multiple-gestation pregnancies and the contribution of assisted-reproduction techniques to their incidence. N Engl J Med (1994) 2.06
Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev (1998) 2.05
Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin production. J Clin Invest (1996) 1.97
Gonadotropin-releasing hormone and its analogues. N Engl J Med (1991) 1.94
Induction of puberty in men by long-term pulsatile administration of low-dose gonadotropin-releasing hormone. N Engl J Med (1982) 1.89
Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback. J Clin Endocrinol Metab (2000) 1.84
The physiology of gonadotropin-releasing hormone (GnRH) secretion in men and women. Recent Prog Horm Res (1985) 1.71
Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. N Engl J Med (1992) 1.69
Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. N Engl J Med (1997) 1.66
Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab (2001) 1.65
Gonadotropin-releasing hormone and its analogs. Annu Rev Med (1994) 1.61
Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone. Endocr Rev (1986) 1.56
The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics. J Clin Endocrinol Metab (2001) 1.56
CHD7 mutations in patients initially diagnosed with Kallmann syndrome--the clinical overlap with CHARGE syndrome. Clin Genet (2008) 1.56
Noninvasive evaluation of cardiac function in hypothyroidism. Response to gradual thyroxine replacement. N Engl J Med (1977) 1.55
Minimal ovarian stimulation for IVF: appraisal of potential benefits and drawbacks. Hum Reprod (1999) 1.45
Characterizing discrete subsets of polycystic ovary syndrome as defined by the Rotterdam criteria: the impact of weight on phenotype and metabolic features. J Clin Endocrinol Metab (2006) 1.41
Defining constant versus variable phenotypic features of women with polycystic ovary syndrome using different ethnic groups and populations. J Clin Endocrinol Metab (2006) 1.38
The genetic and clinical heterogeneity of gonadotropin-releasing hormone deficiency in the human. J Clin Endocrinol Metab (1996) 1.33
The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor. J Clin Endocrinol Metab (2001) 1.26
Characterization of the physiological pattern of episodic gonadotropin secretion throughout the human menstrual cycle. J Clin Endocrinol Metab (1986) 1.24
Osteoporosis in men with idiopathic hypogonadotropic hypogonadism. Ann Intern Med (1987) 1.23
Simulation of the normal menstrual cycle in Kallman's syndrome by pulsatile administration of luteinizing hormone-releasing hormone (LHRH). J Clin Endocrinol Metab (1980) 1.22
A conservative approach to the management of uterine leiomyoma: pituitary desensitization by a luteinizing hormone-releasing hormone analogue. Am J Obstet Gynecol (1983) 1.19
Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab (1989) 1.18
X-linked adrenal hypoplasia congenita: a mutation in DAX1 expands the phenotypic spectrum in males and females. J Clin Endocrinol Metab (1999) 1.17
Therapeutic use of pituitary desensitization with a long-acting lhrh agonist: a potential new treatment for idiopathic precocious puberty. J Clin Endocrinol Metab (1981) 1.17
Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A preliminary report. N Engl J Med (1981) 1.16
Neuroendocrine-gonadal axis in men: frequent sampling of LH, FSH, and testosterone. Am J Physiol (1988) 1.15
A mutation in the follicle-stimulating hormone receptor occurs frequently in human ovarian sex cord tumors. J Clin Endocrinol Metab (1997) 1.14
Successful use of pulsatile gonadotropin-releasing hormone (GnRH) for ovulation induction and pregnancy in a patient with GnRH receptor mutations. J Clin Endocrinol Metab (2000) 1.14
Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease: indirect evidence for partial gonadotroph desensitization. J Clin Endocrinol Metab (1988) 1.14
Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. Endocr Rev (1986) 1.13
Translational careers. Science (2009) 1.13
Neuroendocrine regulation of the corpus luteum in the human. Evidence for pulsatile progesterone secretion. J Clin Invest (1984) 1.12
Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion. J Clin Endocrinol Metab (2001) 1.12
Kisspeptin and GPR54: discovery of a novel pathway in reproduction. J Neuroendocrinol (2008) 1.12
Long-term treatment of central precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. Effects on somatic growth and skeletal maturation. N Engl J Med (1983) 1.10
Potential for fertility with replacement of hypothalamic gonadotropin-releasing hormone in long term female survivors of cranial tumors. J Clin Endocrinol Metab (1994) 1.08
Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency. J Clin Endocrinol Metab (1997) 1.02
Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men. J Clin Endocrinol Metab (1991) 0.99
Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone-deficient men. J Clin Endocrinol Metab (1991) 0.99
The spectrum of abnormal patterns of gonadotropin-releasing hormone secretion in men with idiopathic hypogonadotropic hypogonadism: clinical and laboratory correlations. J Clin Endocrinol Metab (1987) 0.98
Spatial ability in androgen-deficient men. N Engl J Med (1982) 0.98
The longitudinal study of adrenal maturation during gonadal suppression: evidence that adrenarche is a gradual process. J Clin Endocrinol Metab (2001) 0.97
A comparison of 13 different immunometric assay kits for gonadotropins: implications for clinical investigation. J Clin Endocrinol Metab (1994) 0.96
Is obesity an outcome of gonadotropin-releasing hormone agonist administration? Analysis of growth and body composition in 110 patients with central precocious puberty. J Clin Endocrinol Metab (1999) 0.95
Insights into hypothalamic-pituitary dysfunction in polycystic ovary syndrome. J Endocrinol Invest (1998) 0.95
Characterization of unique binding kinetics of follistatin and activin or inhibin in serum. Endocrinology (1994) 0.95
Effects of increasing the frequency of low doses of gonadotropin-releasing hormone (GnRH) on gonadotropin secretion in GnRH-deficient men. J Clin Endocrinol Metab (1987) 0.94
Midcycle levels of sex steroids are sufficient to recreate the follicle-stimulating hormone but not the luteinizing hormone midcycle surge: evidence for the contribution of other ovarian factors to the surge in normal women. J Clin Endocrinol Metab (1995) 0.93
Heterogeneous expression of the potassium-chloride cotransporter KCC2 in gonadotropin-releasing hormone neurons of the adult mouse. Endocrinology (2003) 0.93
Decreased release of gonadotropin-releasing hormone during the preovulatory midcycle luteinizing hormone surge in normal women. Proc Natl Acad Sci U S A (1994) 0.93
The midcycle gonadotropin surge in normal women occurs in the face of an unchanging gonadotropin-releasing hormone pulse frequency. J Clin Endocrinol Metab (1994) 0.92
Myocardial function in hypothyroidism. Relation to disease severity and response to treatment. Arch Intern Med (1978) 0.92
Frequency modulation of follicle-stimulating hormone (FSH) during the luteal-follicular transition: evidence for FSH control of inhibin B in normal women. J Clin Endocrinol Metab (1997) 0.92
Bio- and immunoactive luteinizing hormone responses to low doses of gonadotropin-releasing hormone (GnRH): dose-response curves in GnRH-deficient men. J Clin Endocrinol Metab (1986) 0.91
Importance of inhibin B in the regulation of FSH secretion in the human male. J Clin Endocrinol Metab (2001) 0.91
Gonadotropin pulsations across development. Horm Res (1998) 0.91
Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP. Endocrinology (1996) 0.90
Hypothalamic gonadotropin-releasing hormone secretion and follicle-stimulating hormone dynamics during the luteal-follicular transition. J Clin Endocrinol Metab (1992) 0.90
Progesterone antagonism: science and society. N Engl J Med (1986) 0.90
Divergent responses of gonadotropin subunit messenger RNAs to continuous versus pulsatile gonadotropin-releasing hormone in vitro. Mol Endocrinol (1990) 0.89
Clinical review 4: Diagnosis and treatment of isolated gonadotropin-releasing hormone deficiency in men. J Clin Endocrinol Metab (1990) 0.89
Clinical review 15: Management of ovulatory disorders with pulsatile gonadotropin-releasing hormone. J Clin Endocrinol Metab (1990) 0.88
Ovulation and menstrual function of adolescent girls with central precocious puberty after therapy with gonadotropin-releasing hormone agonists. J Clin Endocrinol Metab (1992) 0.88
Follistatin-activin complexes in human serum and follicular fluid differ immunologically and biochemically. Endocrinology (1996) 0.87
Clinical review 96: Differential control of gonadotropin secretion in the human: endocrine role of inhibin. J Clin Endocrinol Metab (1998) 0.87
Dynamic regulation of follicle-stimulating hormone-beta messenger ribonucleic acid levels by activin and gonadotropin-releasing hormone in perifused rat pituitary cells. Endocrinology (1992) 0.86
Perifusion of rat pituitary cells with gonadotropin-releasing hormone, activin, and inhibin reveals distinct effects on gonadotropin gene expression and secretion. Endocrinology (1993) 0.86
Hypogonadotropic hypogonadism. Endocrinol Metab Clin North Am (1998) 0.86
The effects of continuous androgen secretion on the hypothalamic-pituitary axis in woman: evidence from a luteinized thecoma of the ovary. J Clin Endocrinol Metab (1984) 0.86
Relatively low levels of dimeric inhibin circulate in men and women with polycystic ovarian syndrome using a specific two-site enzyme-linked immunosorbent assay. J Clin Endocrinol Metab (1994) 0.85
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay. J Clin Endocrinol Metab (1999) 0.85
Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient men. J Clin Endocrinol Metab (1990) 0.85
How do academic health centers value and encourage clinical research? Acad Med (2001) 0.85
Comparison of exogenous gonadotropins and pulsatile gonadotropin-releasing hormone for induction of ovulation in hypogonadotropic amenorrhea. J Clin Endocrinol Metab (1993) 0.85
Characterization of inhibin/activin subunit, follistatin, and activin type II receptors in human ovarian cancer cell lines: a potential role in autocrine growth regulation. Endocrinology (1996) 0.85
Changes in growth and serum growth hormone and plasma somatomedin-C levels during suppression of gonadal sex steroid secretion in girls with central precocious puberty. J Clin Endocrinol Metab (1988) 0.85
The biologic activity of a potent analogue of gonadotropin-releasing hormone in normal and hypogonadotropic men. N Engl J Med (1980) 0.84
A randomized, controlled trial of estradiol replacement therapy in women with hypergonadotropic amenorrhea. J Clin Endocrinol Metab (1996) 0.84
Clinical, biochemical, and ovarian morphologic features in women with acanthosis nigricans and masculinization. Obstet Gynecol (1985) 0.83
Genetics of hypogonadotropic hypogonadism. J Endocrinol Invest (2000) 0.83
Interpulse interval of GnRH stimulation independently modulates LH secretion. Am J Physiol (1989) 0.83
A two-site chemiluminescent assay for activin-free follistatin reveals that most follistatin circulating in men and normal cycling women is in an activin-bound state. J Clin Endocrinol Metab (1998) 0.83
Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist. J Clin Endocrinol Metab (1988) 0.83
Inhibin B in males with gonadotropin-releasing hormone (GnRH) deficiency: changes in serum concentration after shortterm physiologic GnRH replacement--a clinical research center study. J Clin Endocrinol Metab (1996) 0.82
Immunoreactive inhibin alpha-subunit in human serum: implications for radioimmunoassay. J Clin Endocrinol Metab (1990) 0.82
Pulsatile gonadotropin secretion after discontinuation of long term gonadotropin-releasing hormone (GnRH) administration in a subset of GnRH-deficient men. J Clin Endocrinol Metab (1989) 0.82
Improved measurement of free alpha subunit of glycoprotein hormones by assay with use of a monoclonal antibody. Clin Chem (1988) 0.82
The effects of the aromatase inhibitor delta 1-testolactone on gonadotropin release and steroid metabolism in polycystic ovarian disease. J Clin Endocrinol Metab (1985) 0.82
Pituitary and gonadal responsiveness is enhanced during GnRH-induced puberty. Am J Physiol (1988) 0.81
Gonadotropin-releasing hormone-induced stimulation and desensitization of free alpha-subunit secretion mirrors luteinizing hormone and follicle-stimulating hormone in perifused rat pituitary cells. Endocrinology (1990) 0.81
Contour of the GnRH pulse independently modulates gonadotropin secretion in the human male. Neuroendocrinology (1996) 0.81
Serum melatonin in central precocious puberty is lower than in age-matched prepubertal children. J Clin Endocrinol Metab (1991) 0.81
Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche. J Clin Invest (1986) 0.81
Effects of decreasing the frequency of gonadotropin-releasing hormone stimulation on gonadotropin secretion in gonadotropin-releasing hormone-deficient men and perifused rat pituitary cells. J Clin Invest (1988) 0.80
The mortician's mystery. Gynecomastia and reversible hypogonadotropic hypogonadism in an embalmer. N Engl J Med (1988) 0.80
Long-term administration of gonadotropin-releasing hormone in men with idiopathic hypogonadotropic hypogonadism. A model for studies of the hormone's physiologic effects. Ann Intern Med (1986) 0.80