Generation, control, and processing of cellular calcium signals.

PubWeight™: 1.80‹?› | Rank: Top 3%

🔗 View Article (PMID 11370791)

Published in Crit Rev Biochem Mol Biol on April 01, 2001

Authors

E Carafoli1, L Santella, D Branca, M Brini

Author Affiliations

1: Department of Biochemistry, University of Padova, Italy. carafoli@civ.bio.unipd.it

Articles citing this

The enigmatic X gene of hepatitis B virus. J Virol (2004) 2.98

Calcium signaling: a tale for all seasons. Proc Natl Acad Sci U S A (2002) 2.92

Calcium: a central regulator of plant growth and development. Plant Cell (2005) 2.33

The L-type calcium channel in the heart: the beat goes on. J Clin Invest (2005) 1.73

Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality. Proc Natl Acad Sci U S A (2006) 1.54

Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics. J Cell Physiol (2011) 1.50

Scanning the human proteome for calmodulin-binding proteins. Proc Natl Acad Sci U S A (2005) 1.49

Non-genomic actions of androgens. Front Neuroendocrinol (2007) 1.48

Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions. J Proteome Res (2007) 1.48

Dose-dependent ATP depletion and cancer cell death following calcium electroporation, relative effect of calcium concentration and electric field strength. PLoS One (2015) 1.46

Plasma membrane Ca2+ ATPases as dynamic regulators of cellular calcium handling. Ann N Y Acad Sci (2007) 1.41

Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Commun Signal (2011) 1.33

Changes in the expression of plasma membrane calcium extrusion systems during the maturation of hippocampal neurons. Hippocampus (2006) 1.29

The temperature-signaling cascade in sponges involves a heat-gated cation channel, abscisic acid, and cyclic ADP-ribose. Proc Natl Acad Sci U S A (2001) 1.25

Plasma-membrane Ca(2+) pumps: structural diversity as the basis for functional versatility. Biochem Soc Trans (2007) 1.25

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proc Natl Acad Sci U S A (2007) 1.22

Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes. Proc Natl Acad Sci U S A (2004) 1.21

Completion of neuronal migration regulated by loss of Ca(2+) transients. Proc Natl Acad Sci U S A (2004) 1.14

Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions. Cell Commun Signal (2011) 1.09

Hepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levels. J Virol (2007) 1.07

Ca2+ signals and death programmes in neurons. Philos Trans R Soc Lond B Biol Sci (2005) 1.07

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. Biochem J (2003) 1.06

Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. J Virol (2006) 1.01

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors. PLoS One (2011) 0.97

The hepatitis B virus X protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake. J Virol (2011) 0.96

NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes. J Biol Chem (2012) 0.96

Calcium influx pathways in breast cancer: opportunities for pharmacological intervention. Br J Pharmacol (2014) 0.96

Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium. J Biol Chem (2008) 0.94

X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: insights into the mechanism and specificity of metal ion binding to an EF-hand. Biochemistry (2012) 0.93

Calpain activation and Na+/Ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate. J Neurosci Res (2010) 0.92

Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin. Endocrinology (2010) 0.89

Calcium dyshomeostasis and pathological calcium signalling in neurological diseases. Cell Calcium (2010) 0.89

Concentration dependent effect of calcium on brain mitochondrial bioenergetics and oxidative stress parameters. Front Neuroenergetics (2013) 0.86

Plasticity of calcium signaling cascades in human embryonic stem cell-derived neural precursors. Stem Cells Dev (2013) 0.86

A secretagogin locus of the mammalian hypothalamus controls stress hormone release. EMBO J (2014) 0.86

Physiological implications of the interaction between the plasma membrane calcium pump and nNOS. Pflugers Arch (2008) 0.86

Contribution of endoplasmic reticulum Ca2+ regulatory mechanisms to the inflammation-induced increase in the evoked Ca2+ transient in rat cutaneous dorsal root ganglion neurons. Cell Calcium (2013) 0.86

Minimization of extracellular space as a driving force in prokaryote association and the origin of eukaryotes. Biol Direct (2014) 0.85

Modeling and analysis of the molecular basis of pain in sensory neurons. PLoS One (2009) 0.84

The significance of the calcium signal in the outer hair cells and its possible role in tinnitus of cochlear origin. Eur Arch Otorhinolaryngol (2004) 0.84

The biology of the germ line in echinoderms. Mol Reprod Dev (2014) 0.84

Evolutionary Adaptations of Plant AGC Kinases: From Light Signaling to Cell Polarity Regulation. Front Plant Sci (2012) 0.84

Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. Adv Drug Deliv Rev (2015) 0.83

How the mountain pine beetle (Dendroctonus ponderosae) breached the Canadian Rocky Mountains. Mol Biol Evol (2014) 0.83

ER-mitochondrial calcium flow underlies vulnerability of mechanosensory hair cells to damage. J Neurosci (2014) 0.83

Structural analysis of calmodulin binding to ion channels demonstrates the role of its plasticity in regulation. Pflugers Arch (2013) 0.83

The regulation of STIM1 by phosphorylation. Commun Integr Biol (2013) 0.82

Alteration of the cortical actin cytoskeleton deregulates Ca2+ signaling, monospermic fertilization, and sperm entry. PLoS One (2008) 0.82

Why Calcium? How Calcium Became the Best Communicator. J Biol Chem (2016) 0.82

Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model. PLoS One (2015) 0.81

Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation. PLoS One (2013) 0.81

Genome-wide investigation and expression analysis of Sodium/Calcium exchanger gene family in rice and Arabidopsis. Rice (N Y) (2015) 0.81

Calcium regulates tertiary structure and enzymatic activity of human endometase/matrilysin-2 and its role in promoting human breast cancer cell invasion. Biochem J (2007) 0.81

Depolarization-induced calcium responses in sympathetic neurons: relative contributions from Ca2+ entry, extrusion, ER/mitochondrial Ca2+ uptake and release, and Ca2+ buffering. J Gen Physiol (2007) 0.80

The biphasic increase of PIP2 in the fertilized eggs of starfish: new roles in actin polymerization and Ca2+ signaling. PLoS One (2010) 0.80

Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis. Cell Death Dis (2013) 0.80

Composition of Lycium barbarum polysaccharides and their apoptosis-inducing effect on human hepatoma SMMC-7721 cells. Food Nutr Res (2015) 0.78

Paclitaxel induces apoptosis in breast cancer cells through different calcium--regulating mechanisms depending on external calcium conditions. Int J Mol Sci (2014) 0.78

Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger. Neurobiol Dis (2012) 0.78

Distinct Cellular Calcium Metabolism in Radiation-sensitive RKO Human Colorectal Cancer Cells. Korean J Physiol Pharmacol (2014) 0.77

Calcium pathway machinery at fertilization in echinoderms. Cell Calcium (2012) 0.77

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization. Reprod Biol Endocrinol (2008) 0.77

Expression of phosphoinositide-specific phospholipase C isoforms in native endothelial cells. PLoS One (2015) 0.76

Molecular modelling and QSAR analysis of some structurally diverse N-type calcium channel blockers. J Mol Model (2009) 0.76

Decreased ADP-ribosyl cyclase activity in peripheral blood mononuclear cells from diabetic patients with nephropathy. Exp Diabetes Res (2009) 0.76

Two-pore channels function in calcium regulation in sea star oocytes and embryos. Development (2014) 0.76

Calcium impacts carbon and nitrogen balance in the filamentous cyanobacterium Anabaena sp. PCC 7120. J Exp Bot (2016) 0.76

Molecular identification, immunolocalization, and characterization of Clonorchis sinensis calmodulin. Parasitol Res (2013) 0.76

Activation of PAC1 Receptors in Rat Cerebellar Granule Cells Stimulates Both Calcium Mobilization from Intracellular Stores and Calcium Influx through N-Type Calcium Channels. Front Endocrinol (Lausanne) (2013) 0.76

Ca2+ signalling and membrane current activated by cADPr in starfish oocytes. Pflugers Arch (2003) 0.76

Ca K-edge XAS as a probe of calcium centers in complex systems. Inorg Chem (2014) 0.75

THE ROLE OF INTRACELLULAR SODIUM (Na) IN THE REGULATION OF CALCIUM (Ca)-MEDIATED SIGNALING AND TOXICITY. Health (Irvine Calif) (2010) 0.75

Calcium Handling by Endoplasmic Reticulum and Mitochondria in a Cell Model of Huntington's Disease. PLoS Curr (2016) 0.75

Nuclear pore complex during neuronal degeneration: cracking the last barrier! Nucleus (2009) 0.75

Calcium activity of upper thoracic dorsal root ganglion neurons in zucker diabetic Fatty rats. Int J Endocrinol (2013) 0.75

Characterization and bioactivity of novel calcium antagonists - N-methoxy-benzyl haloperidol quaternary ammonium salt. Oncotarget (2015) 0.75

The key target of neuroprotection after the onset of ischemic stroke: secretory pathway Ca(2+)-ATPase 1. Neural Regen Res (2015) 0.75

Computational reconstitution of spine calcium transients from individual proteins. Front Synaptic Neurosci (2015) 0.75

Region-specific proteolysis differentially regulates type 1 inositol 1,4,5-trisphosphate receptor activity. J Biol Chem (2017) 0.75

Articles by these authors

Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria. Science (1993) 6.29

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. Nature (1992) 5.17

Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr Biol (1995) 3.44

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. Biophys J (1999) 2.96

Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A (1996) 2.33

Mitochondrial Ca2+ homeostasis in intact cells. J Cell Biol (1994) 2.28

Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo. Curr Biol (1996) 2.10

Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells. EMBO J (1995) 1.96

The long-duration response to L-dopa in the treatment of early PD. Neurology (2000) 1.46

Photoprotein-mediated measurement of calcium ion concentration in mitochondria of living cells. Methods Enzymol (1995) 1.46

Targeting aequorin and green fluorescent protein to intracellular organelles. Gene (1996) 1.39

Double-stranded DNA can be translocated across a planar membrane containing purified mitochondrial porin. FASEB J (1998) 1.33

Mitochondria as biosensors of calcium microdomains. Cell Calcium (1999) 1.30

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proc Natl Acad Sci U S A (2007) 1.22

Calcium pumps: structural basis for and mechanism of calcium transmembrane transport. Curr Opin Chem Biol (2000) 1.16

Expression, partial purification and functional properties of themuscle-specific calpain isoform p94. Eur J Biochem (1999) 1.10

Targeting recombinant aequorin to specific intracellular organelles. Methods Cell Biol (1994) 1.07

DNA translocation across planar bilayers containing Bacillus subtilis ion channels. J Biol Chem (1997) 1.07

Dopamine D2 receptor gene polymorphism and the risk of levodopa-induced dyskinesias in PD. Neurology (1999) 1.05

NAADP+ initiates the Ca2+ response during fertilization of starfish oocytes. FASEB J (2001) 1.04

Targeting GFP to organelles. Methods Cell Biol (1999) 1.00

The rate of ATP synthesis by submitochondrial particles can be independent of the magnitude of the protonmotive force. Biochem J (1980) 0.92

Intercellular adhesion molecule 1 gene polymorphisms in polymyalgia rheumatica/giant cell arteritis: association with disease risk and severity. J Rheumatol (2000) 0.89

New light on mitochondrial calcium. Biofactors (1998) 0.87

The subacute levodopa test for evaluating long-duration response in Parkinson's disease. Ann Neurol (1995) 0.87

Expression of the calsequestrin gene in chicken cerebellum Purkinje neurons. Biochem J (1993) 0.86

Short-term levodopa test assessed by movement time accurately predicts dopaminergic responsiveness in Parkinson's disease. Mov Disord (1997) 0.86

Calcium signalling in the cell nucleus. Cell Calcium (1997) 0.84

Pharmacodynamics of the long-duration response to levodopa in PD. Neurology (1999) 0.84

SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis. J Cell Biol (2001) 0.83

Usefulness of rectal biopsy for the diagnosis of Kufs disease: a controlled study and review of the literature. Eur J Neurol (2012) 0.83

Gene transfer into satellite cell from regenerating muscle: bupivacaine allows beta-Gal transfection and expression in vitro and in vivo. In Vitro Cell Dev Biol Anim (1994) 0.83

Intercellular communication in the early human embryo. Mol Reprod Dev (1991) 0.83

Erythrocyte and reticulocyte indices in iron deficiency in chronic kidney disease: comparison of two methods. Scand J Clin Lab Invest (2009) 0.83

Hematologic values in healthy and small for gestational age newborns. Lab Hematol (2005) 0.81

The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease. Mov Disord (2000) 0.81

Pantethine and pantothenate effect on the CoA content of rat liver. Int J Vitam Nutr Res (1984) 0.81

Intracellular targeting of the photoprotein aequorin: a new approach for measuring, in living cells, Ca2+ concentrations in defined cellular compartments. Cytotechnology (1993) 0.80

The most conserved nuclear-encoded polypeptide of cytochrome c oxidase is the putative zinc-binding subunit: primary structure of subunit V from the slime mold Dictyostelium discoideum. Biochim Biophys Acta (1991) 0.80

Roles of the actin-binding proteins in intracellular Ca2+ signalling. Acta Physiol (Oxf) (2009) 0.79

Cytosolic free calcium concentration in the mitogenic stimulation of T lymphocytes by anti-CD3 monoclonal antibodies. Cell Calcium (1994) 0.79

Gap-junctional permeability in early and cleavage-arrested ascidian embryos. Development (1991) 0.79

Tight junctions and cavitation in the human pre-embryo. Mol Reprod Dev (1992) 0.78

Clarification of factors influencing the nature and magnitude of the protonmotive force in bovine heart submitochondrial particles. Eur J Biochem (1981) 0.78

Apolipoprotein E polymorphisms and Parkinson's disease. Neurosci Lett (1999) 0.77

Rapid important paper Messenger RNA in squid axoplasm. Neurochem Int (1986) 0.77

3-Methylhistidine urinary excretion as an index of skeletal muscle protein metabolism: reference values. G Clin Med (1986) 0.77

Electrical coupling of blastomeres in early embryos of ascidians and sea urchins. Exp Cell Res (1982) 0.77

Structure of the promoter region of the gene encoding cytochrome c oxidase subunit V in Dictyostelium. Eur J Biochem (1993) 0.77

Intracellular targeting of the photoprotein aequorin: A new approach for measuring, in living cells, Ca(2+) concentrations in defined cellular compartments. Cytotechnology (1993) 0.76

Ca2+ signalling and membrane current activated by cADPr in starfish oocytes. Pflugers Arch (2003) 0.76

Fertilization of sea urchin eggs in space and subsequent development under normal conditions. Adv Space Res (1994) 0.76

Sperm-oocyte interaction in the sea-urchin. J Cell Sci (1985) 0.76

Calcium signaling and disease: preface. Biofactors (2011) 0.75

[An unusual pneumomediastinum case in a child caused by spontaneous bronchial rupture]. Minerva Pediatr (2012) 0.75

Mitochondrial studies with the new anaesthetic 2,6-diisopropylphenol. Agressologie (1986) 0.75

[Effect of various general anesthetics on the metabolism of isolated mitochondria]. Minerva Anestesiol (1991) 0.75

[Hypercalcemia due to parathyroid adenoma without associated malignant neoplasms]. G Clin Med (1980) 0.75

Kinetic alterations of the divalent cation-dependent ATPase activities of human erythrocyte membranes induced by blocking the membrane amino groups. Boll Soc Ital Biol Sper (1983) 0.75

An Italian case of CADASIL with mutation CGC-TCG in codon 1006, exon 19 Notch3 gene. Neurol Sci (2004) 0.75

Effect of blocking amino group couples on the mechanism of Mg and (Ca + Mg) ATPase associated with erythrocyte membrane fragments. Boll Soc Ital Biol Sper (1982) 0.75

Stabilizing action of L-carnitine on the energy-linked processes of mitochondria isolated from perfused rat liver. Biochem Pharmacol (1986) 0.75

[Occult cranium bifidum in a newborn baby]. Minerva Pediatr (2012) 0.75

Abnormal intracellular level of Bax in CD3+ cells from untreated B-cell chronic lymphocytic leukemia patients. Lab Hematol (2006) 0.75

General anesthetics: interferences with some mitochondrial energy-dependent mechanisms. Agressologie (1989) 0.75

L-carnitine decreases the recovery time following halothane anesthesia in rats. Agressologie (1987) 0.75

Carnitine effect on heart steatosis induced in rats by rapeseed oil. Int J Vitam Nutr Res (1977) 0.75

Diamide effect on the ouabain-insensitive APTase activity of red cell membrane. Boll Soc Ital Biol Sper (1979) 0.75

L-carnitine effect on halothane-treated mitochondria. Biochem Pharmacol (1986) 0.75

[Changes in the lipid pattern after administration of glucuronyl-glucosaminoglycan sulfate (3 GS) inpatients with with acute coronary syndromes]. Boll Soc Ital Cardiol (1975) 0.75

Uptake and metabolic rate of liposome-entrapped (U-14C)glutamate in rats. Biochem Pharmacol (1976) 0.75

Diamide effect on the hypertonic calcium uptake by rat red blood cells. J Cell Physiol (1978) 0.75

Effects of halothane, enflurane and isoflurane on some energy-converting functions of isolated rat liver mitochondria. Agressologie (1990) 0.75

Studies on the differentiation of egg envelopes. I. The starfish, Astropecten aurantiacus. Dev Biol (1983) 0.75

Intradialytic variations in hemoglobin affinity for oxygen during bicarbonate dialysis and hemodiafiltration. Int J Artif Organs (1990) 0.75

Involvement of long-chain acyl CoA in the antagonistic effects of halothane and L-carnitine on mitochondrial energy-linked processes. Biochem Biophys Res Commun (1986) 0.75

Intradialytic changes of the oxyhaemoglobin dissociation curve during acetate and bicarbonate haemodialysis. Possible interactions with haemodialysis-associated hypoxaemia. Nephrol Dial Transplant (1990) 0.75

[Large scale molecular organization in particles of DNA-poly-L-histidine association]. C R Acad Sci Hebd Seances Acad Sci D (1976) 0.75

Halogenated anesthetics. Alterations of some mitochondrial functions. Agressologie (1986) 0.75

[Influence of nifedipine on blood calcium and on the plasma levels of FSH and LH. Clinical contribution]. Clin Ter (1984) 0.75

Sensitivity to radiations of Mg2+ and (Ca2+ + Mg2+) ATPase activities associated with erythrocyte membrane fragments. Acta Radiol Oncol (1982) 0.75

[Sideropenic anemia and Helicobacter pylori]. Minerva Gastroenterol Dietol (2011) 0.75