K Georgopoulos

Author PubWeight™ 64.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell 1988 6.24
2 Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 1999 5.50
3 A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 1995 4.02
4 Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996 3.91
5 Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J 1996 3.18
6 The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Mol Cell Biol 1994 3.15
7 Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes. EMBO J 1999 3.11
8 Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J 1997 2.71
9 Aiolos regulates B cell activation and maturation to effector state. Immunity 1998 2.24
10 Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity 1999 2.19
11 The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity 2001 2.04
12 Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr Biol 1998 1.92
13 Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. J Exp Med 1999 1.82
14 Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. J Biol Chem 2000 1.81
15 Defects in hemopoietic stem cell activity in Ikaros mutant mice. J Exp Med 1999 1.76
16 Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers. J Exp Med 1991 1.69
17 Control of lymphocyte development by the Ikaros gene family. Curr Opin Immunol 1999 1.69
18 Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage. Immunity 1997 1.56
19 The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse. J Immunol 1996 1.51
20 The linkage between T-cell and dendritic cell development in the mouse thymus. Immunol Rev 1998 1.24
21 Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proc Natl Acad Sci U S A 1986 1.18
22 Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements. Proc Natl Acad Sci U S A 1987 1.13
23 Palliation of malignant gastric outlet obstruction with self-expanding metal stents. Endoscopy 1996 1.04
24 Transcription factors in early T-cell development. Immunol Today 1993 1.00
25 Identification and characterization of a transcriptional regulator for the lck proximal promoter. J Biol Chem 2001 0.97
26 Distinct signals control the hematopoiesis of lymphoid-related dendritic cells. Blood 2000 0.91
27 Characterization and expression of the murine CD3-epsilon gene. Proc Natl Acad Sci U S A 1988 0.89
28 Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system. Cold Spring Harb Symp Quant Biol 1999 0.86
29 The CD3 delta gene encodes multiple transcripts regulated by transcriptional and post-transcriptional mechanisms. Eur J Immunol 1989 0.85
30 A reinvestigation of the cross-reactivity between Klebsiella and HLA-B27 in the aetiology of ankylosing spondylitis. Clin Exp Immunol 1985 0.85
31 Derivation of dendritic cells from myeloid and lymphoid precursors. Int Rev Immunol 2001 0.79
32 Ikaros in hemopoietic lineage determination and homeostasis. Semin Immunol 1998 0.79
33 Palliation of large-bowel obstruction due to recurrent rectosigmoid tumor using self-expandable endoprostheses. Endoscopy 1996 0.77
34 The T cell receptor/T3 complex. Year Immunol 1986 0.75