Published in Nat Rev Mol Cell Biol on June 01, 2001
Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. Biophys J (2006) 19.98
An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein. Proc Natl Acad Sci U S A (2002) 6.37
The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging. Genome Biol (2005) 5.16
Dynamics of putative raft-associated proteins at the cell surface. J Cell Biol (2004) 4.52
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol (2004) 4.41
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Formation of stacked ER cisternae by low affinity protein interactions. J Cell Biol (2003) 3.76
Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin. Nature (2009) 3.31
Synthetic multivalent ligands as probes of signal transduction. Angew Chem Int Ed Engl (2006) 3.29
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. J Biol Chem (2008) 3.13
Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking. Mol Biol Cell (2002) 2.84
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin. EMBO J (2009) 2.78
The fluorescent protein palette: tools for cellular imaging. Chem Soc Rev (2009) 2.69
Electron microscopy of whole cells in liquid with nanometer resolution. Proc Natl Acad Sci U S A (2009) 2.55
Growing dendrites and axons differ in their reliance on the secretory pathway. Cell (2007) 2.51
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol Cell Biol (2004) 2.33
High- and low-mobility populations of HP1 in heterochromatin of mammalian cells. Mol Biol Cell (2004) 2.29
Inefficient degradation of truncated polyglutamine proteins by the proteasome. EMBO J (2004) 2.24
Membrane protein transport between the endoplasmic reticulum and the Golgi in tobacco leaves is energy dependent but cytoskeleton independent: evidence from selective photobleaching. Plant Cell (2002) 2.20
Electron microscopy of specimens in liquid. Nat Nanotechnol (2011) 2.07
Analysis of receptor oligomerization by FRAP microscopy. Nat Methods (2009) 2.06
Nup98 is a mobile nucleoporin with transcription-dependent dynamics. Mol Biol Cell (2002) 2.01
Ku recruits XLF to DNA double-strand breaks. EMBO Rep (2007) 2.00
Quantitative multiphoton spectral imaging and its use for measuring resonance energy transfer. Biophys J (2005) 1.98
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds. Nat Rev Drug Discov (2009) 1.95
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. Biophys J (2005) 1.94
k-Space image correlation spectroscopy: a method for accurate transport measurements independent of fluorophore photophysics. Biophys J (2006) 1.89
FRET detection of cellular alpha4-integrin conformational activation. Biophys J (2003) 1.88
Nucleolus: the fascinating nuclear body. Histochem Cell Biol (2007) 1.87
Second harmonic generating (SHG) nanoprobes for in vivo imaging. Proc Natl Acad Sci U S A (2010) 1.84
Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm. Biophys J (2008) 1.82
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients. Blood (2005) 1.81
Protein folding stability and dynamics imaged in a living cell. Nat Methods (2010) 1.77
Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1. Mol Biol Cell (2010) 1.77
Effects of organelle shape on fluorescence recovery after photobleaching. Biophys J (2005) 1.77
Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium. Mol Biol Cell (2004) 1.76
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol (2011) 1.74
Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates. J Cell Biol (2005) 1.74
Spatial and temporal regulation of focal adhesion kinase activity in living cells. Mol Cell Biol (2007) 1.72
Fluorescence correlation spectroscopy: past, present, future. Biophys J (2011) 1.65
Determinants of histone H1 mobility and chromatin binding in living cells. Nat Struct Mol Biol (2006) 1.64
The DNA binding activity of p53 displays reaction-diffusion kinetics. Biophys J (2006) 1.61
Simulations of (an)isotropic diffusion on curved biological surfaces. Biophys J (2005) 1.57
Rab2 GTPase regulates vesicle trafficking between the endoplasmic reticulum and the Golgi bodies and is important to pollen tube growth. Plant Cell (2002) 1.57
Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells. Proc Natl Acad Sci U S A (2006) 1.57
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell (2009) 1.55
Nanometer-resolution electron microscopy through micrometers-thick water layers. Ultramicroscopy (2010) 1.54
Histone variant H2ABbd confers lower stability to the nucleosome. EMBO Rep (2004) 1.49
The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol (2003) 1.47
Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis. J Biol Chem (2007) 1.46
Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p. J Cell Biol (2002) 1.45
Nucleolus: from structure to dynamics. Histochem Cell Biol (2005) 1.44
Selective mobility and sensitivity to SNAREs is exhibited by the Arabidopsis KAT1 K+ channel at the plasma membrane. Plant Cell (2006) 1.43
Characterization of an improved donor fluorescent protein for Forster resonance energy transfer microscopy. J Biomed Opt (2008) 1.43
Dynamics of Z-band based proteins in developing skeletal muscle cells. Cell Motil Cytoskeleton (2005) 1.43
The potential of high-content high-throughput microscopy in drug discovery. Br J Pharmacol (2007) 1.42
Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol (2012) 1.42
ArfGAP1 dynamics and its role in COPI coat assembly on Golgi membranes of living cells. J Cell Biol (2005) 1.40
Fluorescent proteins: a cell biologist's user guide. Trends Cell Biol (2009) 1.40
The nucleolus: a model for the organization of nuclear functions. Histochem Cell Biol (2006) 1.39
Imaging gene expression in single living cells. Nat Rev Mol Cell Biol (2004) 1.39
The fusome mediates intercellular endoplasmic reticulum connectivity in Drosophila ovarian cysts. Mol Biol Cell (2004) 1.36
Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophys J (2006) 1.36
The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations. PLoS One (2010) 1.34
DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal. Nucleic Acids Res (2014) 1.34
An optimized optogenetic clustering tool for probing protein interaction and function. Nat Commun (2014) 1.33
Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. PLoS One (2010) 1.28
Correlative fluorescence microscopy and scanning transmission electron microscopy of quantum-dot-labeled proteins in whole cells in liquid. ACS Nano (2010) 1.28
The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. PLoS Comput Biol (2008) 1.27
Counting kinetochore protein numbers in budding yeast using genetically encoded fluorescent proteins. Methods Cell Biol (2008) 1.27
Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs. J Neurosci (2009) 1.26
Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives. Trends Biotechnol (2009) 1.25
Proteins on the move: insights gained from fluorescent protein technologies. Nat Rev Mol Cell Biol (2011) 1.25
Peptide amphiphile nanostructure-heparin interactions and their relationship to bioactivity. Biomaterials (2008) 1.24
Triple-color coincidence analysis: one step further in following higher order molecular complex formation. Biophys J (2004) 1.23
Imaging molecular interactions in living cells. Mol Endocrinol (2005) 1.23
Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells. Mol Cell Biol (2008) 1.22
Fluorescent proteins as biomarkers and biosensors: throwing color lights on molecular and cellular processes. Curr Protein Pept Sci (2008) 1.22
Active translocon complexes labeled with GFP-Dad1 diffuse slowly as large polysome arrays in the endoplasmic reticulum. J Cell Biol (2002) 1.21
Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival. Proc Natl Acad Sci U S A (2010) 1.18
A generalization of theory for two-dimensional fluorescence recovery after photobleaching applicable to confocal laser scanning microscopes. Biophys J (2009) 1.18
Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments. Histochem Cell Biol (2005) 1.17
Molecular imaging of homodimeric protein-protein interactions in living subjects. FASEB J (2004) 1.17
Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures. Biophys J (2009) 1.17
A method improving the accuracy of fluorescence recovery after photobleaching analysis. Biophys J (2008) 1.17
Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo. Mol Cell Biol (2005) 1.17
Efficiency of resonance energy transfer in homo-oligomeric complexes of proteins. J Biol Phys (2007) 1.17
Complementation and reconstitution of fluorescence from circularly permuted and truncated green fluorescent protein. Biochemistry (2009) 1.16
Imaging approach for monitoring cellular metabolites and ions using genetically encoded biosensors. Curr Opin Biotechnol (2010) 1.14
Spatial analysis of 3' phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments. Biophys J (2004) 1.13
Hybridization kinetics is different inside cells. Proc Natl Acad Sci U S A (2009) 1.13
Formation and toxicity of soluble polyglutamine oligomers in living cells. PLoS One (2010) 1.12
An integrative model for phytochrome B mediated photomorphogenesis: from protein dynamics to physiology. PLoS One (2010) 1.12
Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nat Methods (2007) 1.11
Computational approaches for modeling regulatory cellular networks. Trends Cell Biol (2004) 1.11
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J Cell Biol (2013) 1.11
Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha. Mol Biol Cell (2007) 1.11
Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion. J Cell Biol (2009) 1.11
Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling. Mol Biol Cell (2005) 1.10
Shining new light on 3D cell motility and the metastatic process. Trends Cell Biol (2009) 1.09
Density of myelinated nerve fibers in the chinchilla cochlea. J Acoust Soc Am (1982) 0.86