Published in Oncogene on April 30, 2001
Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities. EMBO J (2003) 3.93
Hypoxia-responsive transcription factors. Pflugers Arch (2005) 2.64
c-Jun is a negative regulator of myelination. J Cell Biol (2008) 2.27
Transcription factor haploinsufficiency: when half a loaf is not enough. J Clin Invest (2002) 2.23
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. EMBO J (2002) 2.00
Oxidative stress promotes myofibroblast differentiation and tumour spreading. EMBO Mol Med (2010) 1.81
Emerging roles of ATF2 and the dynamic AP1 network in cancer. Nat Rev Cancer (2010) 1.76
JNK signalling modulates intestinal homeostasis and tumourigenesis in mice. EMBO J (2009) 1.74
Transcriptional regulation of hepatic stellate cell activation. Gut (2002) 1.66
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. Mol Cell Biol (2005) 1.50
Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. Proc Natl Acad Sci U S A (2006) 1.37
Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence. APMIS (2009) 1.36
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation. J Cell Biol (2002) 1.28
Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells. Infect Immun (2010) 1.23
Expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/2) in breast cancer. Br J Cancer (2005) 1.22
miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation. Proc Natl Acad Sci U S A (2006) 1.22
The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells. PLoS One (2011) 1.20
Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization. Mol Cell Biol (2003) 1.18
Multiple facets of junD gene expression are atypical among AP-1 family members. Oncogene (2008) 1.17
Ubiquitin-independent proteasomal degradation of Fra-1 is antagonized by Erk1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer. Mol Cell Biol (2007) 1.16
AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription. J Leukoc Biol (2011) 1.10
JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction. Genes Dev (2002) 1.06
JunD regulates lymphocyte proliferation and T helper cell cytokine expression. EMBO J (2004) 1.04
Binding site specificity and factor redundancy in activator protein-1-driven human papillomavirus chromatin-dependent transcription. J Biol Chem (2011) 1.02
The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer. Oncogenesis (2012) 1.01
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection. Front Biosci (2008) 0.99
The role of oxidative stress and inflammation in cardiovascular aging. Biomed Res Int (2014) 0.98
Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation. Nat Cell Biol (2010) 0.96
Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. BMC Cancer (2009) 0.96
In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo. Mol Cell Proteomics (2010) 0.95
Transcription factor proteomics: identification by a novel gel mobility shift-three-dimensional electrophoresis method coupled with southwestern blot and high-performance liquid chromatography-electrospray-mass spectrometry analysis. J Chromatogr A (2011) 0.95
Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cells. Mol Endocrinol (2004) 0.94
Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun. Mol Cell Biol (2004) 0.93
JunB breakdown in mid-/late G2 is required for down-regulation of cyclin A2 levels and proper mitosis. Mol Cell Biol (2008) 0.93
beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes. J Mol Cell Cardiol (2009) 0.92
Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat. J Virol (2012) 0.92
Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation. EMBO J (2013) 0.91
Prostaglandin E₂ induces oncostatin M expression in human chronic wound macrophages through Axl receptor tyrosine kinase pathway. J Immunol (2012) 0.90
Growth factor stimulation induces cell survival by c-Jun. ATF2-dependent activation of Bcl-XL. J Biol Chem (2010) 0.89
Helicobacter pylori and mitogen-activated protein kinases mediate activator protein-1 (AP-1) subcomponent protein expression and DNA-binding activity in gastric epithelial cells. FEMS Immunol Med Microbiol (2008) 0.88
Microarray analysis of B-cell lymphoma cell lines with the t(14;18). J Mol Diagn (2002) 0.88
Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics. Proc Natl Acad Sci U S A (2014) 0.87
Inhibition of liver trans-sulphuration pathway by propargylglycine mimics gene expression changes found in the mammary gland of weaned lactating rats: role of glutathione. Biochem J (2003) 0.87
Stimulation of T cells up-regulates expression of Ifi202, an interferon-inducible lupus susceptibility gene, through activation of JNK/c-Jun pathway. Immunol Lett (2008) 0.86
Sulindac activates NF-κB signaling in colon cancer cells. Cell Commun Signal (2013) 0.85
JunD and JunB integrate prostaglandin E2 activation of breast cancer-associated proximal aromatase promoters. Mol Endocrinol (2011) 0.85
The effects of estrogen and testosterone on gene expression in the rat mesenteric arteries. Vascul Pharmacol (2007) 0.85
The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nat Commun (2016) 0.84
Expression profiling of human hepatoma cells reveals global repression of genes involved in cell proliferation, growth, and apoptosis upon infection with parvovirus H-1. J Virol (2005) 0.83
Activation of AP-1 transcription factors differentiates FGF2 and vascular endothelial growth factor regulation of endothelial nitric-oxide synthase expression in placental artery endothelial cells. J Biol Chem (2010) 0.83
ModuleRole: a tool for modulization, role determination and visualization in protein-protein interaction networks. PLoS One (2014) 0.81
A phase I/II trial of TAC-101, an oral synthetic retinoid, in patients with advanced hepatocellular carcinoma. J Cancer Res Clin Oncol (2008) 0.81
An integrated approach to characterize transcription factor and microRNA regulatory networks involved in Schwann cell response to peripheral nerve injury. BMC Genomics (2013) 0.81
AP-1 transcription factor JunD confers protection from accelerated nephrotoxic nephritis and control podocyte-specific Vegfa expression. Am J Pathol (2011) 0.80
Repression of anti-apoptotic genes via AP-1 as a mechanism of apoptosis induction in ventricular cardiomyocytes. Pflugers Arch (2006) 0.80
Extracellular signal-regulated kinase signaling regulates the opposing roles of JUN family transcription factors at ETS/AP-1 sites and in cell migration. Mol Cell Biol (2014) 0.79
The RhoA transcriptional program in pre-T cells. FEBS Lett (2007) 0.79
Jun is required in Isl1-expressing progenitor cells for cardiovascular development. PLoS One (2013) 0.79
IL-4 inhibition of IL-1 induced Matrix metalloproteinase-3 (MMP-3) expression in human fibroblasts involves decreased AP-1 activation via negative crosstalk involving of Jun N-terminal kinase (JNK). Exp Cell Res (2013) 0.78
C-Jun recruits the NSL complex to regulate its target gene expression by modulating H4K16 acetylation and promoting the release of the repressive NuRD complex. Oncotarget (2015) 0.78
DCC functions as an accelerator of thalamocortical axonal growth downstream of spontaneous thalamic activity. EMBO Rep (2015) 0.78
Genetic interactions between Drosophila melanogaster menin and Jun/Fos. Dev Biol (2006) 0.78
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. Nat Commun (2015) 0.78
Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions. PLoS One (2016) 0.77
A genome wide association study on Newfoundland colorectal cancer patients' survival outcomes. Biomark Res (2015) 0.77
Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells. J Cell Biochem (2013) 0.77
Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development. Mol Cell (2017) 0.76
Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo. PLoS One (2015) 0.75
WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice. BMC Cancer (2017) 0.75
Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats. J Biomed Sci (2015) 0.75
cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation. Oncogene (2016) 0.75
Effect of brain-derived neurotrophic factor on c-jun expression in the rd mouse retina. Int J Ophthalmol (2012) 0.75
Wallerian demyelination: chronicle of a cellular cataclysm. Cell Mol Life Sci (2017) 0.75
The Role of p16(INK4a) Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and Cancer. Int J Mol Sci (2017) 0.75
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