Published in Parasitol Int on September 01, 2000
A pathway for phosphatidylcholine biosynthesis in Plasmodium falciparum involving phosphoethanolamine methylation. Proc Natl Acad Sci U S A (2004) 1.52
Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated. PLoS One (2013) 1.07
Targeting the Lipid Metabolic Pathways for the Treatment of Malaria. Drug Dev Res (2010) 0.98
Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target. PLoS One (2009) 0.98
Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Prog Lipid Res (2013) 0.96
Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy. J Exp Med (2002) 0.94
Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways. J Lipid Res (2010) 0.90
Arrest of nuclear division in Plasmodium through blockage of erythrocyte surface exposed ribosomal protein P2. PLoS Pathog (2012) 0.86
Fatty acids from Plasmodium falciparum down-regulate the toxic activity of malaria glycosylphosphatidylinositols. Infect Immun (2006) 0.84
Uptake of proteins and degradation of human serum albumin by Plasmodium falciparum-infected human erythrocytes. Malar J (2003) 0.78
Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast. Cell Microbiol (2016) 0.76
Copper Homeostasis for the Developmental Progression of Intraerythrocytic Malarial Parasite. Curr Top Med Chem (2016) 0.75
Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways. BMC Syst Biol (2013) 0.75
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science (1996) 12.54
Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrob Agents Chemother (1994) 8.64
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem J (1982) 5.67
Organization of the recA gene of Escherichia coli. Proc Natl Acad Sci U S A (1980) 4.90
Polyphasic taxonomy of the genus Shewanella and description of Shewanella oneidensis sp. nov. Int J Syst Bacteriol (1999) 4.30
CD14 is a pattern recognition receptor. Immunity (1994) 3.79
Nucleotide sequence of the lexA gene of E. coli. Cell (1981) 3.61
Characteristics of purified recA protein and the regulation of its synthesis in vivo. Cold Spring Harb Symp Quant Biol (1979) 2.93
Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat Cell Biol (2000) 2.74
Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene. Proc Natl Acad Sci U S A (1987) 2.54
Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis: a randomized multicenter trial. Endoscopy (2013) 2.34
Membrane lipid biogenesis in Escherichia coli: identification of genetic loci for phosphatidylglycerophosphate synthetase and construction of mutants lacking phosphatidylglycerol. J Biol Chem (1979) 2.33
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.30
Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes. J Biol Chem (1995) 2.25
Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis. Mol Microbiol (2001) 2.22
Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity. Immunity (1996) 2.05
Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J Biol Chem (1998) 1.89
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro. FEBS Lett (1991) 1.78
Epiregulin. A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes. J Biol Chem (1995) 1.77
Functional domains of Escherichia coli recA protein deduced from the mutational sites in the gene. Mol Gen Genet (1984) 1.71
Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. J Biol Chem (2000) 1.65
Thermotoga petrophila sp. nov. and Thermotoga naphthophila sp. nov., two hyperthermophilic bacteria from the Kubiki oil reservoir in Niigata, Japan. Int J Syst Evol Microbiol (2001) 1.58
Simultaneous detection of several Fusarium mycotoxins in cereals, grains, and foodstuffs. J Assoc Off Anal Chem (1981) 1.57
Amino acid sequence of the serine-repeat antigen (SERA) of Plasmodium falciparum determined from cloned cDNA. Mol Biochem Parasitol (1988) 1.56
Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF. Nucleic Acids Res (1991) 1.55
Role of multiple efflux pumps in Escherichia coli in indole expulsion. FEMS Microbiol Lett (1999) 1.54
Two interacting mutations causing temperature-sensitive phosphatidylglycerol synthesis in Escherichia coli membranes. J Bacteriol (1981) 1.51
Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts. FEBS Lett (2000) 1.50
Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. Int Immunol (2001) 1.49
Effect of pH on activities of novel beta-lactamases and beta-lactamase inhibitors against these beta-lactamases. Antimicrob Agents Chemother (1995) 1.46
Growth requirements of hyperthermophilic sulfur-dependent heterotrophic archaea isolated from a shallow submarine geothermal system with reference to their essential amino acids. Appl Environ Microbiol (1994) 1.44
Detergent-resistant phospholipase A of Escherichia coli K-12. Purification and properties. Eur J Biochem (1977) 1.43
Long PCR amplification of Plasmodium falciparum DNA extracted from filter paper blots. Exp Parasitol (2001) 1.41
Silver in sugar particles and systemic argyria. Lancet (1998) 1.39
Macrophage activation by monosaccharide precursors of Escherichia coli lipid A. Proc Natl Acad Sci U S A (1985) 1.39
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol (1999) 1.37
Characterization of two membrane-associated glycolipids from an Escherichia coli mutant deficient in phosphatidylglycerol. J Biol Chem (1981) 1.36
Radiation exposure in endovascular surgery of the head and neck. AJNR Am J Neuroradiol (1994) 1.33
Mitochondrial dysfunction of a cultured Chinese hamster ovary cell mutant deficient in cardiolipin. J Biol Chem (1993) 1.33
Inhibition of Escherichia coli RecA coprotease activities by DinI. EMBO J (1998) 1.32
Host cell-derived sphingolipids are required for the intracellular growth of Chlamydia trachomatis. Cell Microbiol (2000) 1.32
GPI anchoring leads to sphingolipid-dependent retention of endocytosed proteins in the recycling endosomal compartment. EMBO J (2001) 1.31
Complete nucleotide sequence of two new satellite RNAs associated with cucumber mosaic virus. Virology (1988) 1.29
In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64. J Pharmacobiodyn (1986) 1.29
Characterization of cell-surface determinants important for baculovirus infection. Virology (2001) 1.29
Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats. Endocrinology (1995) 1.28
Vacuolar H(+)-ATPase localized in plasma membranes of malaria parasite cells, Plasmodium falciparum, is involved in regional acidification of parasitized erythrocytes. J Biol Chem (2000) 1.26
Sphingolipids are essential for the growth of Chinese hamster ovary cells. Restoration of the growth of a mutant defective in sphingoid base biosynthesis by exogenous sphingolipids. J Biol Chem (1992) 1.25
A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis. J Biol Chem (1997) 1.25
Value of MR cholangiopancreatography in evaluating choledochal cysts. AJR Am J Roentgenol (1998) 1.24
Human cytomegalovirus glycoprotein N (gpUL73-gN) genomic variants: identification of a novel subgroup, geographical distribution and evidence of positive selective pressure. J Gen Virol (2003) 1.24
Pyrimethamine resistant Plasmodium falciparum: overproduction of dihydrofolate reductase by a gene duplication. Mol Biochem Parasitol (1987) 1.23
Mouse rRNA gene transcription factor mUBF requires both HMG-box1 and an acidic tail for nucleolar accumulation: molecular analysis of the nucleolar targeting mechanism. EMBO J (1992) 1.23
Spontaneous occlusion of traumatic carotid cavernous fistula after orbital venography. Surg Neurol (1985) 1.23
Lead discovery of inhibitors of the dihydrofolate reductase domain of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase. Biochem Biophys Res Commun (1997) 1.22
Antibodies reactive with the N-terminal domain of Plasmodium falciparum serine repeat antigen inhibit cell proliferation by agglutinating merozoites and schizonts. Infect Immun (1999) 1.22
Vasa vasorum of the intracranial arteries. Acta Neurochir (Wien) (1998) 1.22
Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats. Endocrinology (1994) 1.21
[Histological study of the outer membrane of chronic subdural hematoma: possible mechanism for expansion of hematoma cavity]. No Shinkei Geka (1993) 1.21
Results of urgent thrombolysis in patients with major stroke and atherothrombotic occlusion of the cervical internal carotid artery. AJNR Am J Neuroradiol (1998) 1.20
RobA-induced multiple antibiotic resistance largely depends on the activation of the AcrAB efflux. Microbiol Immunol (1997) 1.19
Synthesis of functional protein in liposome. J Biosci Bioeng (2001) 1.19
Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2. Biochem Biophys Res Commun (2000) 1.18
Direct packing of the isolated sinus in patients with dural arteriovenous fistulas of the transverse-sigmoid sinus. J Neurosurg (1998) 1.17
Identification of a novel prostaglandin f(2alpha) synthase in Trypanosoma brucei. J Exp Med (2000) 1.17
Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells. A novel evaluation system using an SPT-defective mammalian cell mutant. Biochem Pharmacol (2000) 1.16
Chemical synthesis and biological activity of the gelatinase biosynthesis-activating pheromone of Enterococcus faecalis and its analogs. Biosci Biotechnol Biochem (2001) 1.15
Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells. II. Isolation and characterization of phosphatidylserine auxotrophs. J Biol Chem (1986) 1.15
Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques. J Biol Chem (2000) 1.14
Cardiolipin accumulation in the inner and outer membranes of Escherichia coli mutants defective in phosphatidylserine synthetase. J Bacteriol (1979) 1.14
Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo. FEBS Lett (1991) 1.14
Papain inhibitions by optically active E-64 analogs. J Biochem (1981) 1.14
Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy. Mol Microbiol (1999) 1.11
Structural and functional organization of ColE2 and ColE3 replicons. Mol Gen Genet (1989) 1.10
E-64 [L-trans-epoxysuccinyl-leucyl-amido(4-guanidino)butane] and related epoxides as inhibitors of cysteine proteinases. Acta Biol Med Ger (1981) 1.09
Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin. J Biol Chem (2000) 1.09
A pathological study of intracranial posterior circulation dissecting aneurysms with subarachnoid hemorrhage: report of three autopsied cases and review of the literature. Neurosurgery (1993) 1.09
Impairment of the inferior alveolar nerve after sagittal split osteotomy. J Craniomaxillofac Surg (1989) 1.06
Plasmodium falciparum produces prostaglandins that are pyrogenic, somnogenic, and immunosuppressive substances in humans. J Exp Med (1998) 1.06
Isolation of a chinese hamster ovary (CHO) cDNA encoding phosphatidylglycerophosphate (PGP) synthase, expression of which corrects the mitochondrial abnormalities of a PGP synthase-defective mutant of CHO-K1 cells. J Biol Chem (1999) 1.06
A temperature-sensitive mammalian cell mutant with thermolabile serine palmitoyltransferase for the sphingolipid biosynthesis. J Biol Chem (1990) 1.06
Manganese intoxication during total parenteral nutrition: report of two cases and review of the literature. J Neurol Sci (1999) 1.06
Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol. J Endotoxin Res (2001) 1.04
C-terminal truncated Escherichia coli RecA protein RecA5327 has enhanced binding affinities to single- and double-stranded DNAs. J Mol Biol (1992) 1.04
Cysteinyl residues of Escherichia coli recA protein. Biochemistry (1984) 1.04
Analyses of serum copper and zinc levels and copper/zinc ratios in skin diseases. J Dermatol (1993) 1.04
Radiologic findings in xanthogranulomatous cholecystitis. AJR Am J Roentgenol (1987) 1.03
Hydatidiform mole with a surviving coexisting fetus. Obstet Gynecol (1980) 1.03
Promoter/enhancer cassettes for keratinocyte gene therapy. J Invest Dermatol (1999) 1.03
A somatic cell mutant defective in phosphatidylglycerophosphate synthase, with impaired phosphatidylglycerol and cardiolipin biosynthesis. J Biol Chem (1993) 1.03
Clinical study of enlarged infundibular dilation of the origin of the posterior communicating artery. J Neurosurg (1995) 1.02
Effect of subinhibitory concentrations of macrolides on expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis. Antimicrob Agents Chemother (2000) 1.02
RAD51 homologues in Xenopus laevis: two distinct genes are highly expressed in ovary and testis. Gene (1995) 1.02
Phylogenetic relationships within Taenia taeniaeformis variants and other taeniid cestodes inferred from the nucleotide sequence of the cytochrome c oxidase subunit I gene. Parasitol Res (1995) 1.02
Production of recombinant SERA proteins of Plasmodium falciparum in Escherichia coli by using synthetic genes. Vaccine (1996) 1.02
Immunodiagnosis of alveolar echinococcosis by enzyme-linked immunosorbent assay using a partially purified Em18/16 enriched fraction. Clin Diagn Lab Immunol (1997) 1.02
Computed tomography and histologic appearance of pancreatic metastases from distant sources. Acta Radiol (1990) 1.02