Published in Mol Cell on June 01, 2001
MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol (2010) 5.44
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci U S A (2004) 4.17
The formation of skeletal muscle: from somite to limb. J Anat (2003) 3.37
Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci U S A (2005) 2.38
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J (2006) 2.38
Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions. Mol Cell Biol (2005) 2.19
Invasive growth: from development to metastasis. J Clin Invest (2002) 1.91
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol (2003) 1.91
A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia. Mol Cell Biol (2004) 1.44
Proliferation and invasion: plasticity in tumor cells. Proc Natl Acad Sci U S A (2005) 1.40
Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. Cell Res (2011) 1.24
Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. J Cell Biol (2005) 1.18
Viable hypomorphic signaling mutant of the Met receptor reveals a role for hepatocyte growth factor in postnatal cerebellar development. Proc Natl Acad Sci U S A (2002) 1.17
Negative feedback regulation of Met-dependent invasive growth by Notch. Mol Cell Biol (2005) 1.10
Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage. Mol Cell Biol (2004) 1.09
Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. PLoS Genet (2013) 1.08
Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A (2007) 1.06
Abl interconnects oncogenic Met and p53 core pathways in cancer cells. Cell Death Differ (2011) 1.05
Motor neuron trophic factors: therapeutic use in ALS? Brain Res Rev (2010) 0.98
A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol (2013) 0.90
MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus. J Neurosci (2014) 0.88
Novel roles of c-Met in the survival of renal cancer cells through the regulation of HO-1 and PD-L1 expression. J Biol Chem (2015) 0.87
Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. J Biol Chem (2010) 0.86
Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca(2+)- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells. Biochem J (2003) 0.85
MET receptor tyrosine kinase as an autism genetic risk factor. Int Rev Neurobiol (2013) 0.84
Enhanced neuronal Met signalling levels in ALS mice delay disease onset. Cell Death Dis (2011) 0.83
The Met receptor tyrosine kinase prevents zebrafish primary motoneurons from expressing an incorrect neurotransmitter. Neural Dev (2008) 0.82
Redundant roles for Met docking site tyrosines and the Gab1 pleckstrin homology domain in InlB-mediated entry of Listeria monocytogenes. Infect Immun (2005) 0.81
Synergistic signaling of tumor cell invasiveness by hepatocyte growth factor and hypoxia. J Biol Chem (2014) 0.80
Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation. J Biol Chem (2013) 0.80
Fgfr1 regulates development through the combinatorial use of signaling proteins. Genes Dev (2015) 0.79
Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver. J Hepatol (2012) 0.79
Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures. PLoS One (2012) 0.78
Prognostic value of MET protein overexpression and gene amplification in locoregionally advanced nasopharyngeal carcinoma. Oncotarget (2015) 0.78
Plasticity versus specificity in RTK signalling modalities for distinct biological outcomes in motor neurons. BMC Biol (2014) 0.76
Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis. PLoS Genet (2015) 0.75
TRO40303, a mitochondrial-targeted cytoprotective compound, provides protection in hepatitis models. Pharmacol Res Perspect (2015) 0.75
Alteration status and prognostic value of MET in head and neck squamous cell carcinoma. J Cancer (2016) 0.75
Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol (1979) 27.52
On the Oregon trail: rationing health care. BMJ (1991) 20.63
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet (1999) 11.79
An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol (1995) 10.05
The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol (1984) 9.28
Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes (1997) 8.96
Role of brain insulin receptor in control of body weight and reproduction. Science (2000) 8.14
Onset of NIDDM occurs at least 4-7 yr before clinical diagnosis. Diabetes Care (1992) 7.69
The Wisconsin epidemiologic study of diabetic retinopathy. III. Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 or more years. Arch Ophthalmol (1984) 7.68
Milburn's vision of a new NHS. Adopting the missionary position. BMJ (2001) 7.31
Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease. JAMA (1992) 6.40
Two views on the Griffiths report. The mobilisation of consent versus the management of conflict: decoding the Griffiths report. Br Med J (Clin Res Ed) (1983) 6.16
Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology (1999) 6.07
Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin. The Epidemiology of Hearing Loss Study. Am J Epidemiol (1998) 6.04
The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema. Ophthalmology (1984) 5.91
Explaining outputs of primary health care: population and practice factors. BMJ (1991) 5.61
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature (1995) 5.51
Infant admissions to hospital and maternal smoking. Lancet (1974) 5.49
Prevalence of glaucoma. The Beaver Dam Eye Study. Ophthalmology (1992) 5.35
Risk factors for age-related macular degeneration: Pooled findings from three continents. Ophthalmology (2001) 5.06
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev (1999) 4.75
Variations in budgets of fundholding practices. BMJ (1991) 4.71
Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex. Neuron (2001) 4.62
The Beaver Dam Health Outcomes Study: initial catalog of health-state quality factors. Med Decis Making (1993) 4.46
Essential role for TrkB receptors in hippocampus-mediated learning. Neuron (1999) 4.20
The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology (1993) 4.18
The 14-year incidence of visual loss in a diabetic population. Ophthalmology (1998) 4.08
Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol (2000) 3.94
Cigarette smoking and hearing loss: the epidemiology of hearing loss study. JAMA (1998) 3.86
Identifying the content area for the 51-item National Eye Institute Visual Function Questionnaire: results from focus groups with visually impaired persons. Arch Ophthalmol (1998) 3.75
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature (1994) 3.73
Equity and the NHS: self-reported morbidity, access, and primary care. Br Med J (1980) 3.72
Assessment of cataracts from photographs in the Beaver Dam Eye Study. Ophthalmology (1990) 3.66
Visual impairment in diabetes. Ophthalmology (1984) 3.64
GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science (1994) 3.63
Warning signals from Oregon. BMJ (1992) 3.58
Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol Cell (2000) 3.54
The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. J Gerontol (1976) 3.51
Towards a new pluralism. Health Policy (1987) 3.47
Studies in the distribution of body fat. III. Effects of cigarette smoking. JAMA (1989) 3.44
Diabetic retinopathy. Diabetes Care (1998) 3.39
Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation. J Clin Invest (1982) 3.33
The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER. Arch Ophthalmol (2001) 3.31
Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study. Lancet (2001) 3.28
Diabetic retinopathy as detected using ophthalmoscopy, a nonmydriatic camera and a standard fundus camera. Ophthalmology (1985) 3.20
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J (1991) 3.20
Rationing in practice: the case of in vitro fertilisation. BMJ (1993) 3.20
Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell (1996) 3.19
Priorities and rationing: pragmatism or principles? BMJ (1995) 3.09
An alternative method of grading diabetic retinopathy. Ophthalmology (1986) 3.05
Tyrosine kinase receptor indistinguishable from the c-met protein. Nature (1989) 3.00
trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell (1991) 2.97
A model of the kinetics of insulin in man. J Clin Invest (1974) 2.97
The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man. J Clin Invest (1975) 2.97
Is the risk of diabetic retinopathy greater in non-Hispanic blacks and Mexican Americans than in non-Hispanic whites with type 2 diabetes? A U.S. population study. Diabetes Care (1998) 2.97
Effects of arterial versus venous sampling on analysis of glucose kinetics in man. J Appl Physiol (1976) 2.93
Characterization of a multicomponent receptor for GDNF. Nature (1996) 2.92
Ten-year incidence of visual loss in a diabetic population. Ophthalmology (1994) 2.91
Cause-specific mortality in a population-based study of diabetes. Am J Public Health (1991) 2.89
Low prevalence of hearing aid use among older adults with hearing loss: the Epidemiology of Hearing Loss Study. J Am Geriatr Soc (1998) 2.88
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature (1999) 2.80
Skeletal myogenic progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers and contribute to postnatal muscle growth and regeneration. J Cell Biol (1999) 2.74
The politics of change. BMJ (1991) 2.70
Prevalence of age-related lens opacities in a population. The Beaver Dam Eye Study. Ophthalmology (1992) 2.68
Puzzling out priorities. Why we must acknowledge that rationing is a political process. BMJ (1998) 2.65
Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking. Clin Pharmacol Ther (1975) 2.64
Intraocular pressure in an American community. The Beaver Dam Eye Study. Invest Ophthalmol Vis Sci (1992) 2.55
Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality. Surv Ophthalmol (2001) 2.51
Performance-based and self-assessed measures of visual function as related to history of falls, hip fractures, and measured gait time. The Beaver Dam Eye Study. Ophthalmology (1998) 2.50
Is the English NHS underfunded? BMJ (1999) 2.47
Association of NIDDM and hearing loss. Diabetes Care (1998) 2.45
The GlideScope Video Laryngoscope: randomized clinical trial in 200 patients. Br J Anaesth (2004) 2.41
Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Science (1997) 2.40
Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study. Genet Epidemiol (1994) 2.39
Controlling the gatekeepers: the accountability of general practitioners. J R Coll Gen Pract (1986) 2.39
Refractive status in the Beaver Dam Eye Study. Invest Ophthalmol Vis Sci (1994) 2.36
From evidence-based medicine to evidence-based policy? J Health Serv Res Policy (2000) 2.36
Alcohol intake and the risk of coronary heart disease mortality in persons with older-onset diabetes mellitus. JAMA (1999) 2.35
The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XIII. Relationship of serum cholesterol to retinopathy and hard exudate. Ophthalmology (1991) 2.34
The 14-year incidence of lower-extremity amputations in a diabetic population. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. Diabetes Care (1999) 2.33
On the way to Calvary. Ministers should realise the command and control model the white paper entails. BMJ (1998) 2.30
Methodology for retinal photography and assessment of diabetic retinopathy: the EURODIAB IDDM complications study. Diabetologia (1995) 2.27
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J (1996) 2.26
Production and characterization of monoclonal antibodies against the Epstein-Barr virus membrane antigen. J Virol (1982) 2.26
Comparison between ophthalmoscopy and fundus photography in determining severity of diabetic retinopathy. Ophthalmology (1985) 2.26
Why Britain is reorganizing its national health service--yet again. Health Aff (Millwood) (1998) 2.25
The Jerusalem perinatal study. 1. Design and organization of a continuing, community-based, record-linked survey. Isr J Med Sci (1970) 2.24
Is there evidence of an estrogen effect on age-related lens opacities? The Beaver Dam Eye Study. Arch Ophthalmol (1994) 2.23
Diabetes and diabetic retinopathy in a Mexican-American population: Proyecto VER. Diabetes Care (2001) 2.16
A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature (1997) 2.16
The validity of self-reported and surrogate-reported cataract and age-related macular degeneration in the Beaver Dam Eye Study. Am J Epidemiol (1991) 2.14
Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development. Cell (1996) 2.14
Intraosseous lipoma: report of 35 new cases and a review of the literature. Skeletal Radiol (2003) 2.13
Dietary fat and age-related maculopathy. Arch Ophthalmol (1995) 2.11
HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death. EMBO J (1996) 2.09
Insulin control of glucose metabolism in man: a new kinetic analysis. J Clin Invest (1975) 2.09
Plasma selenium level before diagnosis and the risk of prostate cancer development. J Urol (2001) 2.07
A diet history questionnaire ranks nutrient intakes in middle-aged and older men and women similarly to multiple food records. J Nutr (1993) 2.06
Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron (2001) 2.06