Published in Annu Rev Biophys Biomol Struct on January 01, 2001
The structure of FtsZ filaments in vivo suggests a force-generating role in cell division. EMBO J (2007) 3.44
Regulation of microtubule motors by tubulin isotypes and post-translational modifications. Nat Cell Biol (2014) 2.45
Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol (2004) 2.42
Treadmilling of a prokaryotic tubulin-like protein, TubZ, required for plasmid stability in Bacillus thuringiensis. Genes Dev (2007) 2.21
Some assembly required: yeast septins provide the instruction manual. Trends Cell Biol (2005) 1.96
Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations. Curr Opin Genet Dev (2011) 1.84
Drugs that target dynamic microtubules: a new molecular perspective. Med Res Rev (2011) 1.70
In search of an optimal ring to couple microtubule depolymerization to processive chromosome motions. Proc Natl Acad Sci U S A (2007) 1.57
Identification of a dynein interacting domain in the papillomavirus minor capsid protein l2. J Virol (2006) 1.53
Force production by depolymerizing microtubules: a theoretical study. Proc Natl Acad Sci U S A (2005) 1.49
Microtubules regulate disassembly of epithelial apical junctions. BMC Cell Biol (2006) 1.31
A molecular-mechanical model of the microtubule. Biophys J (2005) 1.28
Distinct structural domains within C19ORF5 support association with stabilized microtubules and mitochondrial aggregation and genome destruction. Cancer Res (2005) 1.28
Acetylated microtubules are required for fusion of autophagosomes with lysosomes. BMC Cell Biol (2010) 1.24
Obstacles on the microtubule reduce the processivity of Kinesin-1 in a minimal in vitro system and in cell extract. Biophys J (2009) 1.19
The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood (2007) 1.17
Microtubule-associated proteins in higher plants. J Plant Res (2007) 1.13
Tubulin proteomics: towards breaking the code. Anal Biochem (2008) 1.10
RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem (2008) 1.06
Physics of bacterial morphogenesis. Microbiol Mol Biol Rev (2011) 1.03
Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane. Carcinogenesis (2008) 1.03
Translocation of incoming pseudorabies virus capsids to the cell nucleus is delayed in the absence of tegument protein pUL37. J Virol (2009) 0.98
A new model for binding of kinesin 13 to curved microtubule protofilaments. J Cell Biol (2009) 0.98
The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model. Mol Biol Cell (2011) 0.98
Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1. Plant Cell (2011) 0.97
Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis. J Cell Biol (2005) 0.96
Subcellular localization and secretion of activity-dependent neuroprotective protein in astrocytes. Neuron Glia Biol (2004) 0.96
Visualisation of a kinesin-13 motor on microtubule end mimics. J Mol Biol (2008) 0.93
A beta-tubulin mutation selectively uncouples nuclear division and cytokinesis in Tetrahymena thermophila. Eukaryot Cell (2004) 0.93
Microtubule stability studied by three-dimensional molecular theory of solvation. Biophys J (2006) 0.91
An orphan kinesin in trypanosomes cooperates with a kinetoplastid-specific kinesin to maintain cell morphology by regulating subpellicular microtubules. J Cell Sci (2012) 0.90
Mouse norovirus 1 utilizes the cytoskeleton network to establish localization of the replication complex proximal to the microtubule organizing center. J Virol (2012) 0.90
The role of Tau protein in resistance to paclitaxel. Cancer Chemother Pharmacol (2011) 0.89
Structural rearrangements in tubulin following microtubule formation. EMBO Rep (2005) 0.88
Variability-based sequence alignment identifies residues responsible for functional differences in alpha and beta tubulin. Protein Sci (2004) 0.86
Preclinical profile of cabazitaxel. Drug Des Devel Ther (2014) 0.85
Nitric oxide and cyclic nucleotides: their roles in junction dynamics and spermatogenesis. Oxid Med Cell Longev (2009) 0.85
Structural model of a complex between the heterotrimeric G protein, Gsalpha, and tubulin. Biochim Biophys Acta (2008) 0.82
Peloruside A inhibits microtubule dynamics in a breast cancer cell line MCF7. Invest New Drugs (2010) 0.82
Pressure-induced changes in the structure and function of the kinesin-microtubule complex. Biophys J (2009) 0.82
Six subgroups and extensive recent duplications characterize the evolution of the eukaryotic tubulin protein family. Genome Biol Evol (2014) 0.81
Synergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermine. Cancer Lett (2006) 0.81
Meiosis-specific failure of cell cycle progression in fission yeast by mutation of a conserved beta-tubulin residue. Mol Biol Cell (2003) 0.81
Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies? Oxid Med Cell Longev (2015) 0.80
IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma. Oncotarget (2015) 0.80
Hsp70 and thermal pretreatment mitigate developmental damage caused by mitotic poisons in Drosophila. Cell Stress Chaperones (2002) 0.80
Molecular modeling of the axial and circumferential elastic moduli of tubulin. Biophys J (2008) 0.79
The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines. Curr Drug Targets Infect Disord (2002) 0.79
Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy. Am J Hum Genet (2016) 0.78
The state of the guanosine nucleotide allosterically affects the interfaces of tubulin in protofilament. J Comput Aided Mol Des (2012) 0.78
Microtubules as a critical target for arsenic toxicity in lung cells in vitro and in vivo. Int J Environ Res Public Health (2012) 0.78
Site-specific chemistry on the microtubule polymer. J Am Chem Soc (2013) 0.78
Erucin, the major isothiocyanate in arugula (Eruca sativa), inhibits proliferation of MCF7 tumor cells by suppressing microtubule dynamics. PLoS One (2014) 0.77
Proteomic profiling of rabbit embryonic stem cells derived from parthenotes and fertilized embryos. PLoS One (2013) 0.77
New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry. Sci Rep (2015) 0.76
In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells. Br J Pharmacol (2014) 0.76
ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling. Oncotarget (2016) 0.76
γ-Tubulin complex in Trypanosoma brucei: molecular composition, subunit interdependence and requirement for axonemal central pair protein assembly. Mol Microbiol (2015) 0.76
Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR). Integr Biol (Camb) (2015) 0.76
Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics. Mol Ther (2015) 0.76
Identification of 12Cysbeta on tubulin as the binding site of tubulyzine. Bioorg Med Chem (2005) 0.76
The impact of cytoskeletal organization on the local regulation of neuronal transport. Nat Rev Neurosci (2017) 0.75
A previously undescribed tubulin binder. Proc Natl Acad Sci U S A (2014) 0.75
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability. Cell Cycle (2016) 0.75
Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host. World J Biol Chem (2017) 0.75
The structured core of human β tubulin confers isotype-specific polymerization properties. J Cell Biol (2016) 0.75
Anthelmintic drug albendazole arrests human gastric cancer cells at the mitotic phase and induces apoptosis. Exp Ther Med (2016) 0.75
Transcriptome Profiling Revealed Stress-Induced and Disease Resistance Genes Up-Regulated in PRSV Resistant Transgenic Papaya. Front Plant Sci (2016) 0.75
Multiple signal classification algorithm for super-resolution fluorescence microscopy. Nat Commun (2016) 0.75
A phase I dose escalation study of TTI-237 in patients with advanced malignant solid tumors. Invest New Drugs (2010) 0.75
Targeting mitotic pathways for endocrine-related cancer therapeutics. Endocr Relat Cancer (2017) 0.75