Paget disease of bone: mapping of two loci at 5q35-qter and 5q31.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMC 1235483)

Published in Am J Hum Genet on July 25, 2001

Authors

N Laurin1, J P Brown, A Lemainque, A Duchesne, D Huot, Y Lacourcière, G Drapeau, J Verreault, V Raymond, J Morissette

Author Affiliations

1: Molecular Endocrinology and Oncology Research Center, CHUL Research Center, Québec, Qc, Canada G1V 4G2.

Articles citing this

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Am J Hum Genet (2002) 3.00

RACK1, A multifaceted scaffolding protein: Structure and function. Cell Commun Signal (2011) 2.16

Paget disease of bone. J Clin Invest (2005) 1.92

Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone. Nat Genet (2010) 1.58

Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35. Am J Hum Genet (2001) 1.14

Guidelines for diagnosis and management of Paget's disease of bone in Japan. J Bone Miner Metab (2006) 1.04

The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes. Hum Genet (2010) 0.97

Genetically engineered mouse models and human osteosarcoma. Clin Sarcoma Res (2012) 0.96

Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone. J Bone Miner Res (2009) 0.94

Linkage of Paget disease of bone to a novel region on human chromosome 18q23. Am J Hum Genet (2001) 0.91

Emerging strategies and therapies for treatment of Paget's disease of bone. Drug Des Devel Ther (2011) 0.87

Gene expression profile in osteoclasts from patients with Paget's disease of bone. Bone (2009) 0.84

Alternative splicing in osteoclasts and Paget's disease of bone. BMC Med Genet (2014) 0.80

Paget's Disease of Bone: A Review of Epidemiology, Pathophysiology and Management. Ther Adv Musculoskelet Dis (2009) 0.79

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone. Hum Mol Genet (2015) 0.78

Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone. Bone (2012) 0.77

Detection of SQSTM1/P392L post-zygotic mutations in Paget's disease of bone. Hum Genet (2014) 0.77

Genetics of Paget's disease of bone. Bonekey Rep (2015) 0.76

Clinical and Genetic Advances in Paget's Disease of Bone: a Review. Clin Rev Bone Miner Metab (2016) 0.75

Paget's disease of bone or osteopetrosis? Clin Rheumatol (2005) 0.75

Articles cited by this

Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet (1984) 28.51

A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature (1996) 27.61

PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25

Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet (1996) 17.95

The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance. Nat Genet (1995) 10.17

Avoiding recomputation in linkage analysis. Hum Hered (1994) 8.39

Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines. In Vitro (1984) 7.23

A rapid method for the purification of DNA from blood. Nucleic Acids Res (1987) 5.96

Allele frequency estimation from data on relatives. Am J Hum Genet (1991) 5.62

Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with Paget disease. J Bone Miner Res (1996) 2.33

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat Genet (2000) 2.13

Incorrect specification of marker allele frequencies: effects on linkage analysis. Am J Hum Genet (1993) 2.10

Paget's disease of bone: the Lancashire focus. Br Med J (1980) 1.66

Nuclear inclusions in Paget's disease of bone. Science (1976) 1.57

A common gene for juvenile and adult-onset primary open-angle glaucomas confined on chromosome 1q. Am J Hum Genet (1995) 1.40

Viral antigens in osteoclasts from Paget's disease of bone. Lancet (1980) 1.34

Genetic linkage of familial expansile osteolysis to chromosome 18q. Hum Mol Genet (1994) 1.32

Familial aggregation of Paget's disease of bone. J Bone Miner Res (1991) 1.26

Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin Orthop Relat Res (1984) 1.14

Frequency and characteristics of familial aggregation of Paget's disease of bone. J Bone Miner Res (1995) 1.13

The number of families required to detect or exclude linkage heterogeneity. Am J Hum Genet (1986) 1.13

A probable linkage between familial Paget's disease and the HLA loci. Aust N Z J Med (1982) 1.12

Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma. Nat Genet (1998) 1.11

Linkage analysis under locus heterogeneity: behaviour of the A-test in complex analyses. Hum Hered (1997) 1.10

Bone marrow mononuclear cells from patients with Paget's disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence. J Clin Endocrinol Metab (1995) 1.09

A negative search for a paramyxoviral etiology of Paget's disease of bone: molecular, immunological, and ultrastructural studies in UK patients. J Bone Miner Res (2000) 1.07

Canine distemper virus localised in bone cells of patients with Paget's disease. Bone (1991) 1.06

Bone tissue in Paget's disease of bone. Ultrastructure and Immunocytology. Arthritis Rheum (1980) 1.04

Familial Paget's disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q. Bone (2000) 1.04

Genetic linkage of Paget disease of the bone to chromosome 18q. Am J Hum Genet (1997) 1.03

Fine structure of nuclei and cytoplasm of osteoclasts in Paget's disease of bone. Histopathology (1980) 1.02

Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity. J Bone Miner Res (1998) 1.02

Skeletal distribution and biochemical parameters of Paget's disease. Clin Orthop Relat Res (1987) 1.00

Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone. Exp Hematol (1999) 1.00

The epidemiology of Paget's disease of bone. Br Med Bull (1984) 0.97

Geographic variation in the prevalence of Paget's disease of bone. Radiology (1969) 0.97

Evidence for linkage between HLA and Paget's disease. Transplant Proc (1977) 0.96

Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma. Calcif Tissue Int (2001) 0.95

Diagnostic procedures for Paget's disease. Radiologic, pathologic, and laboratory testing. Endocrinol Metab Clin North Am (1995) 0.95

Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction. J Bone Miner Res (1991) 0.94

The genetics of Paget's disease of the bone. J Clin Endocrinol Metab (2001) 0.94

Microfilaments associated with Paget's disease of bone: comparison with nucleocapsids of measles virus and respiratory syncytial virus. Intervirology (1982) 0.92

Ultrastructural features of the osteoclasts from Paget's disease of bone in relation to a viral aetiology. J Clin Pathol (1982) 0.91

Clinical features and pharmacologic treatment of Paget's disease. Endocrinol Metab Clin North Am (1995) 0.90

A family study of Paget's disease of bone. J Epidemiol Community Health (1983) 0.90

Familial Paget's disease of bone: nonlinkage to the PDB1 and PDB2 loci on chromosomes 6p and 18q in a large pedigree. J Bone Miner Res (2001) 0.90

Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase chain reaction. Bone (1998) 0.90

Heterogeneity in Paget disease of the bone. Am J Med Genet (2000) 0.88

Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone. J Bone Miner Res (1994) 0.87

Absence of HLA linkage in a family with osteitis deformans (Paget's disease of bone). Tissue Antigens (1988) 0.85

Radiological prevalence of Paget's disease in Dunedin, New Zealand. Br Med J (Clin Res Ed) (1983) 0.84

Paget's disease of bone in two American cities. Br Med J (1980) 0.83

Viral behavior of paracrystalline inclusions in osteoclasts of Paget's disease of bone. Ultrastruct Pathol (1996) 0.82

Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone. Bone (2000) 0.80

Current prevalence of Paget's disease of bone in a region of France (Anjou). Rev Rhum Engl Ed (1995) 0.77

Paramyxoviruses and Paget's disease. J Med Virol (1993) 0.76

Paget's disease of bone in Ireland. Br Med J (Clin Res Ed) (1983) 0.76

Articles by these authors

A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature (1996) 27.61

Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science (1998) 17.91

An STS-based map of the human genome. Science (1995) 17.72

The 1993-94 Généthon human genetic linkage map. Nat Genet (1994) 17.64

A second-generation linkage map of the human genome. Nature (1992) 16.32

A gene map of the human genome. Science (1996) 14.32

A physical map of 30,000 human genes. Science (1998) 12.43

The current and future market for veterinarians and veterinary medical services in the United States. J Am Vet Med Assoc (1999) 9.90

Finding protein similarities with nucleotide sequence databases. Methods Enzymol (1990) 6.63

A radiation hybrid map of the human genome. Hum Mol Genet (1996) 4.75

Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. N Engl J Med (1998) 4.38

Canadian normative data for the SF-36 health survey. Canadian Multicentre Osteoporosis Study Research Group. CMAJ (2000) 3.77

The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J Biol Chem (1996) 3.26

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02

Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet (1984) 2.85

Evaluation of decision rules for referring women for bone densitometry by dual-energy x-ray absorptiometry. JAMA (2001) 2.70

Cell surface antigens of human melanoma identified by monoclonal antibody. Proc Natl Acad Sci U S A (1979) 2.40

Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. Am J Hum Genet (1998) 2.34

The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int (2001) 2.32

Vaccinia virus encodes a polypeptide homologous to epidermal growth factor and transforming growth factor. Nature (1985) 2.15

Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms. Proc Natl Acad Sci U S A (1980) 2.14

A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res (1998) 2.12

Selective inactivation of the transacylase components of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli. Biochem J (1976) 2.10

A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds. Mutat Res (1980) 1.89

The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study. Osteoporos Int (2008) 1.86

New selective agonists for neurokinin receptors: pharmacological tools for receptor characterization. Trends Pharmacol Sci (1988) 1.83

Aftereffects of exercise on regional and systemic hemodynamics in hypertension. Hypertension (1992) 1.82

ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension. J Hum Hypertens (1999) 1.81

Monoclonal mouse antibodies raised against human lung carcinoma. Cancer Res (1986) 1.75

Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues. Proc Natl Acad Sci U S A (1981) 1.70

The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int (2007) 1.64

Preoperative localization of parathyroid lesions in hyperparathyroidism: relationship between technetium-99m-MIBI uptake and oxyphil cell content. J Nucl Med (1998) 1.64

Oral leukoplakia status six weeks after cessation of smokeless tobacco use. J Am Dent Assoc (1999) 1.58

Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains. EMBO J (1988) 1.57

Pulmonary function and airway responsiveness during long-term therapy with captopril. JAMA (1989) 1.55

Mutagenesis by 9,10-anthraquinone derivatives and related compounds in Salmonella typhimurium. Mutat Res (1976) 1.51

Potency equivalency factors for some polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbon derivatives. Regul Toxicol Pharmacol (1998) 1.51

Pharmacological receptors for substance P and neurokinins. Life Sci (1987) 1.50

Comparison of the effects of epithelium removal and of an enkephalinase inhibitor on the neurokinin-induced contractions of guinea-pig isolated trachea. Br J Pharmacol (1988) 1.49

The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study. Osteoporos Int (2007) 1.48

The association between osteoporotic fractures and health-related quality of life as measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int (2003) 1.47

Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence. Proc Natl Acad Sci U S A (1986) 1.46

Preliminary results on the mental development of hypothyroid infants detected by the Quebec Screening Program. J Pediatr (1983) 1.46

Follow-up at ages 5 and 7 years on mental development in children with hypothyroidism detected by Quebec Screening Program. J Pediatr (1985) 1.46

Efficacy and safety of a novel delayed-release risedronate 35 mg once-a-week tablet. Osteoporos Int (2011) 1.45

Human melanoma-associated antigen p97 is structurally and functionally related to transferrin. Nature (1982) 1.45

Modification of a screening program for neonatal hypothyroidism. J Pediatr (1978) 1.44

Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy. J Clin Invest (1983) 1.42

An upper limit on the stochastic gravitational-wave background of cosmological origin. Nature (2009) 1.42

Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate. Proc Natl Acad Sci U S A (1988) 1.41

Antibody response of mice to chemically induced tumors. Proc Natl Acad Sci U S A (1978) 1.41

New selective bradykinin receptor antagonists and bradykinin B2 receptor characterization. Trends Pharmacol Sci (1990) 1.40

A common gene for juvenile and adult-onset primary open-angle glaucomas confined on chromosome 1q. Am J Hum Genet (1995) 1.40

Vaccinia virus-infected cells release a novel polypeptide functionally related to transforming and epidermal growth factors. Proc Natl Acad Sci U S A (1985) 1.39

Use of phalangeal bone mineral density and multi-site speed of sound conduction to monitor therapy with alendronate in postmenopausal women. Osteoporos Int (2002) 1.39

On the carcinogenicity of cadmium by the oral route. Regul Toxicol Pharmacol (1992) 1.39

Dilemmas in caries diagnosis. J Am Dent Assoc (1993) 1.39

Protein antigens of normal and malignant human cells identified by immunoprecipitation with monoclonal antibodies. J Biol Chem (1980) 1.37

A microassay for antibody binding to tumor cell surface antigens using 125I-labelled protein a from Staphylococcus aureus. J Immunol Methods (1977) 1.36

Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms. Mol Cell Biol (1995) 1.35

Diagnosis of and therapy for solid tumors with radiolabeled antibodies and immune fragments. Cancer Treat Rep (1984) 1.35

The burden of illness of osteoporosis in Canada. Osteoporos Int (2012) 1.34

Report of the Canadian Hypertension Society Consensus Conference: 2. Diagnosis of hypertension in adults. CMAJ (1993) 1.32

The actions of kinin antagonists on B1 and B2 receptor systems. Eur J Pharmacol (1986) 1.31

Molecular genetics of the glaucomas: mapping of the first five "GLC" loci. Am J Hum Genet (1997) 1.29

Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies. J Immunol (1981) 1.27

Hsc70-binding peptides selected from a phage display peptide library that resemble organellar targeting sequences. J Biol Chem (1995) 1.27

Dopaminergic receptors in the anterior pituitary gland. Correlation of [3H]dihydroergocryptine binding with the dopaminergic control of prolactin release. J Biol Chem (1978) 1.26

The tau protein in human cerebrospinal fluid in Alzheimer's disease consists of proteolytically derived fragments. J Neurochem (1997) 1.26

Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test: activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources. Mutat Res (1979) 1.24

Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos. Osteoporos Int (2010) 1.24

Different receptors are involved in the endothelium-mediated relaxation and the smooth muscle contraction of the rabbit pulmonary artery in response to substance P and related neurokinins. Eur J Pharmacol (1986) 1.24

Isolated four-chamber working swine heart model. Ann Thorac Surg (2000) 1.24

Imaging of melanoma with L-131-labeled monoclonal antibodies. J Nucl Med (1983) 1.24

Relative potencies of neurokinins in guinea pig trachea and human bronchus. Eur J Pharmacol (1987) 1.22

Kinin receptor subtypes. J Cardiovasc Pharmacol (1990) 1.21

Indirect 125I-labeled protein A assay for monoclonal antibodies to cell surface antigens. J Immunol Methods (1979) 1.20

Prevention of mental retardation in offspring of hyperphenylalaninemic mothers. Am J Public Health (1982) 1.19

Linkage of benign familial infantile convulsions to chromosome 16p12-q12 suggests allelism to the infantile convulsions and choreoathetosis syndrome. Am J Hum Genet (2001) 1.19

A highly sensitive method for amino-acid analysis by a double-isotope-labelling technique using dansyl chloride. Eur J Biochem (1973) 1.18

An amino acid sequence in the active site of lipoamide dehydrogenase from the 2-oxoglutarate dehydrogenase complex of E. coli (Crookes strain). FEBS Lett (1972) 1.16

Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis Study. J Bone Miner Res (2003) 1.16

Assignment of the gene for human melanoma-associated antigen p97 to chromosome 3. Nature (1983) 1.16

Incidence of breast-feeding in a low socioeconomic group of mothers in the United States: ethnic patterns. Pediatrics (1984) 1.15

Detection of fos protein during osteogenesis by monoclonal antibodies. Mol Cell Biol (1988) 1.15

Respiration of Lactobacillus casei. Can J Microbiol (1968) 1.14

Characterization of neurokinin receptors in various isolated organs by the use of selective agonists. Life Sci (1987) 1.14

Clinical features and motives among 42 artifactual illness patients. Br J Med Psychol (1983) 1.12

Social support, social influence, ethnicity and the breastfeeding decision. Soc Sci Med (1983) 1.12

Receptors for substance P and related neurokinins. Pharmacology (1989) 1.11

Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin. J Pharmacol Exp Ther (1994) 1.11

Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma. Nat Genet (1998) 1.11

Risk factors for low BMD in healthy men age 50 years or older: a systematic review. Osteoporos Int (2008) 1.11

Denosumab compared with risedronate in postmenopausal women suboptimally adherent to alendronate therapy: efficacy and safety results from a randomized open-label study. Bone (2013) 1.10

Unique and common tumor-specific transplantation antigens of chemically induced mouse sarcomas. Int J Cancer (1978) 1.10

Nuchal cord as a cause of neonatal anemia. Am J Dis Child (1985) 1.10

The rat isolated portal vein: a preparation sensitive to neurokinins, particularly neurokinin B. Eur J Pharmacol (1987) 1.08

A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group. Am J Med (1999) 1.08