Published in Am J Physiol Heart Circ Physiol on September 01, 2001
Pathophysiology of sleep apnea. Physiol Rev (2010) 4.69
Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest (2002) 2.89
Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression. J Clin Invest (2003) 2.36
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. J Clin Invest (2002) 1.80
eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity. J Endocrinol (2011) 1.60
Endothelial dysfunction: the early predictor of atherosclerosis. Cardiovasc J Afr (2012) 1.55
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats. Am J Physiol Heart Circ Physiol (2010) 1.54
Cellular signaling and NO production. Pflugers Arch (2010) 1.38
Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging. Lipids Health Dis (2011) 1.22
Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease. Nitric Oxide (2011) 1.21
Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells. J Biol Chem (2009) 1.20
Endothelial dysfunction: a strategic target in the treatment of hypertension? Pflugers Arch (2010) 1.14
Mechanisms of diesel-induced endothelial nitric oxide synthase dysfunction in coronary arterioles. Environ Health Perspect (2010) 1.14
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vasc Health Risk Manag (2005) 1.10
Vascular Protection Following Cerebral Ischemia and Reperfusion. J Neurol Neurophysiol (2011) 1.06
Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits. Circulation (2005) 1.06
Vascular physiology of a Ca2+ mobilizing second messenger - cyclic ADP-ribose. J Cell Mol Med (2006) 1.02
Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. J Appl Physiol (1985) (2008) 1.01
GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension. Hypertension (2010) 0.99
Natural antioxidants and hypertension: promise and challenges. Cardiovasc Ther (2010) 0.98
Effects of sleep-disordered breathing on cerebrovascular regulation: A population-based study. Am J Respir Crit Care Med (2010) 0.92
Endothelial dysfunction in diabetes: pathogenesis, significance, and treatment. Rev Diabet Stud (2013) 0.91
Therapeutic Potential of the Nitrite-Generated NO Pathway in Vascular Dysfunction. Front Immunol (2013) 0.88
Cerebral vascular dysregulation in the ischemic brain. Handb Clin Neurol (2009) 0.87
NO and the vasculature: where does it come from and what does it do? Heart Fail Rev (2002) 0.85
Mediators of CD18/P-selectin-dependent constriction of venule-paired arterioles in hypercholesterolemia. Microvasc Res (2006) 0.84
Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase. Front Immunol (2013) 0.83
Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling. Free Radic Biol Med (2013) 0.83
Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats. J Physiol (2004) 0.82
PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice. Brain Res (2012) 0.81
A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization. J Biol Chem (2013) 0.81
Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice. J Neurochem (2015) 0.81
Coronary microvascular dysfunction in the setting of chronic ischemia is independent of arginase activity. Microvasc Res (2007) 0.80
Tetrahydrobiopterin prevents platelet-activating factor-induced intestinal hypoperfusion and necrosis: Role of neuronal nitric oxide synthase. Crit Care Med (2005) 0.80
Back to the salt mines-- endothelial dysfunction in hypertension and compensatory role of endothelium-derived hyperpolarizing factor (EDHF). J Physiol (2002) 0.80
More sweetness than light? A search for the causes of diabetic vasculopathy. J Clin Invest (2001) 0.79
Regulation of Coronary Vasomotor Function by Reactive Oxygen Species. Mol Med Ther (2012) 0.79
Obstructive Sleep Apnea, Oxidative Stress, and Cardiovascular Disease: Evidence from Human Studies. Oxid Med Cell Longev (2015) 0.78
Treatment With Tetrahydrobiopterin Overcomes Brain Death-Associated Injury in a Murine Model of Pancreas Transplantation. Am J Transplant (2015) 0.78
Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress. PLoS One (2015) 0.75
Synergistic interaction between enalapril, L-arginine and tetrahydrobiopterin in smooth muscle cell apoptosis and aortic remodeling induction in SHR. Br J Pharmacol (2004) 0.75
Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway. Korean J Physiol Pharmacol (2010) 0.75
The Role of -786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome. Int J Endocrinol (2011) 0.75
Deleterious effects of maternal ingestion of cocoa upon fetal ductus arteriosus in late pregnancy. Front Pharmacol (2014) 0.75
Similarities in the Metabolic Reprogramming of Immune System and Endothelium. Front Immunol (2017) 0.75