Published in Nat Neurosci on September 01, 2001
Spider-venom peptides as therapeutics. Toxins (Basel) (2010) 1.44
High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One (2007) 1.38
Role of voltage-gated calcium channels in ascending pain pathways. Brain Res Rev (2008) 1.35
Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol Cell Proteomics (2012) 1.16
The solute carrier 6 family of transporters. Br J Pharmacol (2012) 1.14
Conotoxin gene superfamilies. Mar Drugs (2014) 1.03
Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history. Toxicon (2010) 1.00
Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae. PLoS One (2014) 0.99
Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels. Br J Pharmacol (2012) 0.98
Targeting voltage-gated calcium channels for neuropathic pain management. Neurotherapeutics (2009) 0.94
Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor. Br J Pharmacol (2009) 0.89
Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins. Biochemistry (2007) 0.88
De novo sequencing and disulfide mapping of a bromotryptophan-containing conotoxin by Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2006) 0.88
BmK-YA, an enkephalin-like peptide in scorpion venom. PLoS One (2012) 0.84
Tyrosine-rich conopeptides affect voltage-gated K+ channels. J Biol Chem (2008) 0.82
Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors. Br J Pharmacol (2010) 0.82
Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. BMC Struct Biol (2007) 0.82
Bioactive marine drugs and marine biomaterials for brain diseases. Mar Drugs (2014) 0.81
Venom effects on monoaminergic systems. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2004) 0.80
High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing. Gigascience (2016) 0.78
Synthesis and solid-phase application of suitably protected gamma-hydroxyvaline building blocks. J Org Chem (2007) 0.78
Conopeptide ρ-TIA defines a new allosteric site on the extracellular surface of the α1B-adrenoceptor. J Biol Chem (2012) 0.78
A novel conotoxin, qc16a, with a unique cysteine framework and folding. Peptides (2011) 0.77
Effects of ρ-Da1a a peptidic α(1) (A) -adrenoceptor antagonist in human isolated prostatic adenoma and anaesthetized rats. Br J Pharmacol (2013) 0.76
Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties. Br J Clin Pharmacol (2016) 0.75
A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus). Mar Drugs (2017) 0.75
The vexed question of authorship: views of researchers in a British medical faculty. BMJ (1997) 10.22
Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial. JAMA (2000) 6.41
Design and use of questionnaires: a review of best practice applicable to surveys of health service staff and patients. Health Technol Assess (2001) 5.84
Control of mating preferences in mice by genes in the major histocompatibility complex. J Exp Med (1976) 5.52
The permeability of the endplate channel to organic cations in frog muscle. J Gen Physiol (1980) 5.00
SEROLOGICAL REACTIONS WITH AN INDIFFERENT STREPTOCOCCUS IN PRIMARY ATYPICAL PNEUMONIA. Science (1943) 4.85
The permeability of endplate channels to monovalent and divalent metal cations. J Gen Physiol (1980) 4.72
Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J (1994) 4.46
Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc Natl Acad Sci U S A (1989) 4.13
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. Cell (1998) 3.79
Mycotic aneurysms of the thoracic and abdominal aorta and iliac arteries: experience with anatomic and extra-anatomic repair in 33 cases. J Vasc Surg (2001) 3.78
Structural basis for control by phosphorylation. Chem Rev (2001) 3.53
Identification of patients with acute AIDS-associated cryptococcal meningitis who can be effectively treated with fluconazole: the role of antifungal susceptibility testing. Clin Infect Dis (1996) 3.52
Effect of audit and feedback, and reminder messages on primary-care radiology referrals: a randomised trial. Lancet (2001) 3.44
Emergence of heterogeneous intermediate vancomycin resistance in Staphylococcus aureus isolates in the Düsseldorf area. J Antimicrob Chemother (1999) 3.42
The interaction of mycoplasmas with mammalian cells. I. HeLa cells, neutrophils, and eosinophils. J Exp Med (1966) 3.38
Informed consent in emergency research. Consensus statement from the Coalition Conference of Acute Resuscitation and Critical Care Researchers. JAMA (1995) 3.25
Recognition among mice. Evidence from the use of a Y-maze differentially scented by congenic mice of different major histocompatibility types. J Exp Med (1979) 3.23
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation (2001) 3.15
Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J Biol Chem (2000) 3.06
Comparison of direct electron microscopy, immune electron microscopy, and rotavirus enzyme-linked immunosorbent assay for detection of gastroenteritis viruses in children. J Clin Microbiol (1981) 3.05
Does bullying cause emotional problems? A prospective study of young teenagers. BMJ (2001) 3.04
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. J Cell Biol (1990) 3.03
Distinctive urinary odors governed by the major histocompatibility locus of the mouse. Proc Natl Acad Sci U S A (1981) 2.68
Tensile properties of the human femur-anterior cruciate ligament-tibia complex. The effects of specimen age and orientation. Am J Sports Med (1991) 2.64
Sialic acid binding sites: role in hemagglutination by Mycoplasma gallisepticum. Science (1966) 2.62
Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience (2002) 2.57
Ionic currents in molluscan soma. Annu Rev Neurosci (1980) 2.57
Electrophoresis in agarose and acrylamide gels. Methods Enzymol (1987) 2.53
Inactivation of penicillins by carbohydrate solutions at alkaline pH. N Engl J Med (1970) 2.52
Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. J Mol Biol (2000) 2.43
Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant. J Biol Chem (1993) 2.40
Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. Proc Natl Acad Sci U S A (1988) 2.37
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J Immunol (2001) 2.37
STUDIES ON A NON-HEMOLYTIC STREPTOCOCCUS ISOLATED FROM THE RESPIRATORY TRACT OF HUMAN BEINGS : II. IMMUNOLOGICAL CHARACTERISTICS OF STREPTOCOCCUS MG. J Exp Med (1944) 2.34
Dermoscopy of Bowen's disease. Br J Dermatol (2004) 2.34
Studies of PPLO infection. II. The neurotoxin of Mycoplasma neurolyticum. J Exp Med (1966) 2.34
Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. J Med Chem (1999) 2.33
Prospective evaluation of emergency department medical clearance. Ann Emerg Med (1994) 2.30
Cytotoxicity of microglia. Glia (1993) 2.29
alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. Proc Natl Acad Sci U S A (1998) 2.28
Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. Lancet (1999) 2.27
PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic. EMBO J (2001) 2.26
Familial imprinting determines H-2 selective mating preferences. Science (1988) 2.25
A VIRUS RECOVERED FROM PATIENTS WITH PRIMARY ATYPICAL PNEUMONIA. Science (1943) 2.25
A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides. Protein Sci (1994) 2.24
Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail. EMBO J (1995) 2.22
Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is? Biochemistry (1998) 2.21
Studies of PPLO infection. I. The production of cerebral polyarteritis by Mycoplasma gallisepticum in turkeys; the neurotoxic property of the Mycoplasma. J Exp Med (1966) 2.13
Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. J Physiol (1979) 2.06
Is admission medically justified for all patients with acute stroke or transient ischemic attack? Ann Emerg Med (1995) 2.05
New-onset atrial fibrillation: when is admission medically justified? Acad Emerg Med (1996) 2.04
Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study. Stroke (2000) 2.03
Block of endplate channels by permeant cations in frog skeletal muscle. J Gen Physiol (1981) 2.00
Maintenance of wakefulness test and multiple sleep latency test. Measurement of different abilities in patients with sleep disorders. Chest (1992) 1.97
Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors. Diabetes Obes Metab (2011) 1.97
Heart diseases affecting the liver and liver diseases affecting the heart. Am Heart J (2000) 1.94
Systematic reviews--triumph of form over substance? Clin Otolaryngol (2006) 1.93
Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa. Am J Clin Nutr (2001) 1.91
[Acquired atrophic pigmented band-like lesions following Blaschko's lines]. Ann Dermatol Venereol (1992) 1.89
E. coli hemolysin E (HlyE, ClyA, SheA): X-ray crystal structure of the toxin and observation of membrane pores by electron microscopy. Cell (2000) 1.86
Studies of PPLO infection. V. Inhibition of lymphocyte mitosis and antibody formation by mycoplasmal extracts. J Exp Med (1969) 1.86
Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone. J Clin Invest (1974) 1.85
Recognition of H-2 types in relation to the blocking of pregnancy in mice. Science (1983) 1.83
Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway. J Cell Biol (1997) 1.82
STUDIES ON PRIMARY ATYPICAL PNEUMONIA. I. CLINICAL FEATURES AND RESULTS OF LABORATORY INVESTIGATIONS. J Clin Invest (1945) 1.82
Sensory distinction between H-2b and H-2bm1 mutant mice. Proc Natl Acad Sci U S A (1983) 1.79
Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine. Biochemistry (1982) 1.78
Gallstone pancreatitis: a prospective study on the incidence of cholangitis and clinical predictors of retained common bile duct stones. Am J Gastroenterol (1998) 1.77
Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease: a multicenter study. Circulation (1996) 1.76
Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue Cell (1987) 1.74
A marker for Stevens-Johnson syndrome ...: ethnicity matters. Pharmacogenomics J (2006) 1.73
Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model. J Am Coll Cardiol (2001) 1.73
Altered nucleic acid metabolism in human cell cultures infected with mycoplasma. Proc Natl Acad Sci U S A (1968) 1.73
Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylation. EMBO J (1997) 1.71
Implementing the Food and Drug Administration's final rule for waiver of informed consent in certain emergency research circumstances. Acad Emerg Med (1999) 1.71
Cell culture models of trophoblast II: trophoblast cell lines--a workshop report. Placenta (2000) 1.70
Functional group contributions to drug-receptor interactions. J Med Chem (1984) 1.70
Clinical validation of a structural porous tantalum biomaterial for adult reconstruction. J Bone Joint Surg Am (2004) 1.68
Ciguatera: recent advances but the risk remains. Int J Food Microbiol (2000) 1.67
Immediate countershock versus cardiopulmonary resuscitation before countershock in a 5-minute swine model of ventricular fibrillation arrest. Ann Emerg Med (2000) 1.66
Determining the need for admission in patients with new-onset seizures. Ann Emerg Med (1994) 1.64
Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells. Science (1988) 1.64
Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. J Pharmacol Exp Ther (1998) 1.63
STUDIES ON A NON-HEMOLYTIC STREPTOCOCCUS ISOLATED FROM THE RESPIRATORY TRACT OF HUMAN BEINGS : I. BIOLOGICAL CHARACTERISTICS OF STREPTOCOCCUS MG. J Exp Med (1944) 1.63
Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis. J Mol Biol (2001) 1.62
Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1. Biochemistry (1995) 1.61
Attentional control of visual perception: cortical and subcortical mechanisms. Cold Spring Harb Symp Quant Biol (1990) 1.61
Evaluation and management of children younger than two years old with apparently minor head trauma: proposed guidelines. Pediatrics (2001) 1.61
Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man. Clin Pharmacol Ther (1974) 1.61
Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum Mutat (1993) 1.59
Chemosensory recognition of phenotypes determined by the Tla and H-2K regions of chromosome 17 of the mouse. Proc Natl Acad Sci U S A (1982) 1.59
Outcome of out-of-hospital postcountershock asystole and pulseless electrical activity versus primary asystole and pulseless electrical activity. Crit Care Med (2001) 1.59
Hereditary non-polyposis colorectal cancer and the role of hPMS2 and hEXO1 mutations. Clin Genet (2004) 1.59
The interaction of mycoplasmas with mammalian cells. II. Monocytes and lymphocytes. J Exp Med (1966) 1.57
In vivo electrophysiologic studies in endothelial nitric oxide synthase (eNOS)-deficient mice. J Cardiovasc Electrophysiol (2001) 1.56