Published in J Control Release on September 11, 2001
Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect (2005) 3.57
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci U S A (2004) 2.03
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines. Nat Mater (2010) 1.67
Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages. J Thromb Haemost (2015) 1.41
Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles. PLoS One (2009) 1.31
Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection. J Biol Chem (2011) 1.28
In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles. Proc Natl Acad Sci U S A (2005) 1.22
High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis. Infect Immun (2005) 1.19
Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol (2006) 1.18
Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model. Anticancer Drugs (2010) 1.08
Advances in the design and delivery of peptide subunit vaccines with a focus on toll-like receptor agonists. Expert Rev Vaccines (2010) 0.96
Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats. Int J Pharm (2010) 0.94
The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells. Biomaterials (2012) 0.92
The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide. Front Microbiol (2012) 0.89
Leukotriene B4 enhances innate immune defense against the puerperal sepsis agent Streptococcus pyogenes. J Immunol (2013) 0.88
Current understanding of interactions between nanoparticles and the immune system. Toxicol Appl Pharmacol (2015) 0.82
Evaluation of PEG and mPEG-co-(PGA-co-PDL) microparticles loaded with sodium diclofenac. Saudi Pharm J (2013) 0.82
A Review of Intra- and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish. J Immunol Res (2015) 0.82
Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation. Int J Nanomedicine (2014) 0.81
Biomaterial Strategies for Immunomodulation. Annu Rev Biomed Eng (2015) 0.79
Multimeric peptide-based PEG nanocarriers with programmable elimination properties. Biomaterials (2009) 0.78
Interaction of micron and nano-sized particles with cells of the dura mater. J Biomed Mater Res B Appl Biomater (2014) 0.77
Presentation Modality of Glycoconjugates Modulates Dendritic Cell Phenotype. Biomater Sci (2014) 0.76
Effects of ovalbumin protein nanoparticle vaccine size and coating on dendritic cell processing. Biomater Sci (2016) 0.76
Effect of Experimental Parameters on Alginate/Chitosan Microparticles for BCG Encapsulation. Mar Drugs (2016) 0.76
Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo. J Control Release (2016) 0.76
Biodistribution and fate of core-labeled (125)I polymeric nanocarriers prepared by Flash NanoPrecipitation (FNP). J Mater Chem B Mater Biol Med (2016) 0.75
Irradiation Enhances the Ability of Monocytes as Nanoparticle Carrier for Cancer Therapy. PLoS One (2015) 0.75
Phenotype and polarization of autologous T cells by biomaterial-treated dendritic cells. J Biomed Mater Res A (2014) 0.75
Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo. Mol Ther Nucleic Acids (2014) 0.75
Coating doxorubicin-loaded nanocapsules with alginate enhances therapeutic efficacy against Leishmania in hamsters by inducing Th1-type immune responses. Br J Pharmacol (2014) 0.75
Neisseria lactamica antigens complexed with a novel cationic adjuvant. Hum Vaccin Immunother (2013) 0.75
HIV-1 sensitivity to zidovudine and clinical outcome in children. Lancet (1992) 2.93
The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm Res (1997) 2.28
Influenza A vaccine decreases the incidence of otitis media in 6- to 30-month-old children in day care. Arch Pediatr Adolesc Med (1995) 2.04
Silk fibroin as an organic polymer for controlled drug delivery. J Control Release (2006) 1.71
Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat. Eur J Biochem (1988) 1.69
Transjugular intrahepatic portosystemic stent-shunt (TIPS) in the treatment of Budd-Chiari syndrome. J Hepatol (1993) 1.63
Transient cortical blindness and bioccipital brain lesions in two patients with acute intermittent porphyria. Ann Intern Med (1995) 1.58
Phenotypic characterization of human umbilical vein endothelial (ECV304) and urinary carcinoma (T24) cells: endothelial versus epithelial features. In Vitro Cell Dev Biol Anim (2001) 1.54
Architecture and polymorphism of fibrillar supramolecular assemblies produced by in vitro aggregation of human calcitonin. J Struct Biol (1995) 1.47
The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors. AAPS PharmSci (1999) 1.47
Interference of antibody production to hepatitis B surface antigen in a combination hepatitis A/hepatitis B vaccine. J Infect Dis (1999) 1.45
Occurrence and management of hepatitis B virus reactivation following kidney transplantation. Clin Nephrol (1998) 1.44
Identifying human immunodeficiency virus infection at birth: application of polymerase chain reaction to Guthrie cards. J Pediatr (1993) 1.41
Silk based biomaterials to heal critical sized femur defects. Bone (2006) 1.40
Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells. Bioconjug Chem (2003) 1.39
Images in cardiovascular medicine. Idiopathic hypereosinophilic vasculitis. Circulation (1995) 1.39
Effects and uptake of gold nanoparticles deposited at the air-liquid interface of a human epithelial airway model. Toxicol Appl Pharmacol (2009) 1.39
Surveillance of transcriptomes in basic military trainees with normal, febrile respiratory illness, and convalescent phenotypes. Genes Immun (2005) 1.37
Effect of scaffold design on bone morphology in vitro. Tissue Eng (2006) 1.28
BMP-silk composite matrices heal critically sized femoral defects. Bone (2007) 1.22
Secondary prevention of myocardial infarction: a comparison of acetylsalicylic acid, placebo and phenprocoumon. Haemostasis (1980) 1.22
Dynamics of tight and adherens junctions under EGTA treatment. J Membr Biol (2002) 1.17
Equilibration and exchange of fluorescently labeled molecules in skinned skeletal muscle fibers visualized by confocal microscopy. Biophys J (1995) 1.16
Microencapsulation of DNA using poly(DL-lactide-co-glycolide): stability issues and release characteristics. J Control Release (1999) 1.16
Self-reported zidovudine adherence among pregnant women with human immunodeficiency virus infection in four US states. Am J Obstet Gynecol (2001) 1.15
Spot-blot hybridization assay for the detection of hepatitis B virus DNA in serum: factors determining its sensitivity and specificity. Hepatology (1987) 1.15
Interfacial adsorption and aggregation associated changes in secondary structure of human calcitonin monitored by ATR-FTIR spectroscopy. Biochemistry (1994) 1.10
Long-term follow-up of posttransfusion and sporadic chronic hepatitis non-A, non-B and frequency of circulating antibodies to hepatitis C virus (HCV). J Hepatol (1990) 1.09
Duck hepatitis B virus: DNA polymerase and reverse transcriptase activities of replicative complexes isolated from liver and their inhibition in vitro. Virology (1988) 1.09
Inhibition of duck hepatitis B virus infection by lysosomotropic agents. Virology (1991) 1.08
Secondary prevention of myocardial infarction. Comparison of acetylsalicylic acid, phenprocoumon and placebo. A multicenter two-year prospective study. Thromb Haemost (1979) 1.08
In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J (1993) 1.07
HIV-1 infected women and prenatal care utilization: barriers and facilitators. AIDS Patient Care STDS (2000) 1.06
Fatal PML associated with efalizumab therapy: insights into integrin αLβ2 in JC virus control. Neurology (2012) 1.04
Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters. Biopharm Drug Dispos (2003) 1.03
Novel peptide conjugates for tumor-specific chemotherapy. J Med Chem (2001) 1.02
A single administration of tetanus toxoid in biodegradable microspheres elicits T cell and antibody responses similar or superior to those obtained with aluminum hydroxide. Vaccine (1995) 1.02
Induction of drug metabolizing enzymes by sulfinpyrazone. Eur J Clin Pharmacol (1981) 1.02
Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells. J Control Release (2001) 1.01
Monitoring of the internalization of neuropeptide Y on neuroblastoma cell line SK-N-MC. Eur J Biochem (2000) 0.99
Importance of the test medium for the release kinetics of a somatostatin analogue from poly(D,L-lactide-co-glycolide) microspheres. Int J Pharm (1999) 0.98
Role of integrin expression in adenovirus-mediated gene delivery to the intestinal epithelium. Hum Gene Ther (1998) 0.98
Translocation of human calcitonin in respiratory nasal epithelium is associated with self-assembly in lipid membrane. Biochemistry (1998) 0.98
MDCK cell cultures as an epithelial in vitro model: cytoskeleton and tight junctions as indicators for the definition of age-related stages by confocal microscopy. Pharm Res (1998) 0.97
Cell cultures as tools in biopharmacy. Eur J Pharm Sci (2000) 0.97
Penicillin-induced coagulation disorder. Lancet (1976) 0.96
Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium. J Pharm Sci (2000) 0.95
No entry for TAT(44-57) into liposomes and intact MDCK cells: novel approach to study membrane permeation of cell-penetrating peptides. Biochim Biophys Acta (2003) 0.95
Surface modification of PLGA microspheres. J Biomed Mater Res A (2003) 0.95
Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells. J R Soc Interface (2010) 0.94
Platelet hyperaggregability as a consequence of the nephrotic syndrome. Thromb Res (1981) 0.94
Utility of an HIV-1 RNA assay in the diagnosis of acute retroviral syndrome. South Med J (2000) 0.94
P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels. J Pharm Sci (1998) 0.93
Drug microencapsulation by PLA/PLGA coacervation in the light of thermodynamics. 1. Overview and theoretical considerations. J Pharm Sci (1998) 0.93
Improving stability and release kinetics of microencapsulated tetanus toxoid by co-encapsulation of additives. Pharm Res (1998) 0.92
Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections. Int J Pharm (2000) 0.91
Synthesis of bioadhesive poly(acrylic acid) nano- and microparticles using an inverse emulsion polymerization method for the entrapment of hydrophilic drug candidates. J Control Release (1998) 0.91
Fate of interleukin-6 in the rat. Involvement of skin in its catabolism. Eur J Biochem (1990) 0.91
Revisiting PLA/PLGA microspheres: an analysis of their potential in parenteral vaccination. Eur J Pharm Biopharm (2000) 0.90
Overexpression of human intestinal oligopeptide transporter in mammalian cells via adenoviral transduction. Pharm Res (1998) 0.90
Lipoproteins from Borrelia burgdorferi applied in liposomes and presented by dendritic cells induce CD8(+) T-lymphocytes in vitro. Cell Immunol (2000) 0.89
Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy. Pharm Res (2001) 0.89
Suramin prevents duck hepatitis B virus infection in vivo. Antimicrob Agents Chemother (1993) 0.89
Growth patterns reflect response to antiretroviral therapy in HIV-positive infants: potential utility in resource-poor settings. AIDS Patient Care STDS (2004) 0.89
Composition effects on the pH of a hydraulic calcium phosphate cement. J Mater Sci Mater Med (1997) 0.89
Quality improvement of spray-dried, protein-loaded D,L-PLA microspheres by appropriate polymer solvent selection. J Microencapsul (1995) 0.88
Effect of several additives and their admixtures on the physico-chemical properties of a calcium phosphate cement. J Mater Sci Mater Med (2000) 0.88
Latent hepatitis B virus infection with full-length viral genome in a patient serologically immune to hepatitis B virus infection. Liver (1988) 0.87
The German-Austrian aspirin trial: a comparison of acetylsalicylic acid, placebo and phenprocoumon in secondary prevention of myocardial infarction. On behalf of the German-Austrian Study Group. Circulation (1980) 0.87
Transport and metabolic pathway of thymocartin (TP4) in excised bovine nasal mucosa. J Pharm Pharmacol (1996) 0.87
Comparative pharmacokinetic and cytotoxic analysis of three different formulations of mitoxantrone in mice. Br J Cancer (1997) 0.87
[Sulfinpyrazone (Anturan) versus placebo following surgical reconstruction of the femoral artery in arterial occlusive diseases]. Vasa (1983) 0.87
Towards clinical testing of a single-administration tetanus vaccine based on PLA/PLGA microspheres. Vaccine (2000) 0.87
MHC class I- and class II-restricted processing and presentation of microencapsulated antigens. Vaccine (1999) 0.87
Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain. Mol Cell Biol (1994) 0.86
Diamonds in the rough: protein crystals from a formulation perspective. Pharm Res (2001) 0.86
Transport of alkamides from Echinacea species through Caco-2 monolayers. Planta Med (2002) 0.85
In vitro aging of a calcium phosphate cement. J Mater Sci Mater Med (2000) 0.85
Gentamicin-loaded hydraulic calcium phosphate bone cement as antibiotic delivery system. J Pharm Sci (1997) 0.85
Electron microscopic studies on intracellular phage development--history and perspectives. Micron (1995) 0.85
The effect of bezafibrate on the fibrinolytic enzyme system and the drug interaction with racemic phenprocoumon. Atherosclerosis (1978) 0.85
Towards the predictability of drug-lipid membrane interactions: the pH-dependent affinity of propanolol to phosphatidylinositol containing liposomes. Pharm Res (1998) 0.85
Degradation mechanism and stability of 5-aminolevulinic acid. J Pharm Sci (2000) 0.85
P-Glycoprotein in cell cultures: a combined approach to study expression, localisation, and functionality in the confocal microscope. Eur J Pharm Sci (2000) 0.84
Function and immunolocalization of overexpressed human intestinal H+/peptide cotransporter in adenovirus-transduced Caco-2 cells. AAPS PharmSci (1999) 0.84
The adjuvant effect of bacitracin on nasal absorption of gonadorelin and buserelin in rats. Pharm Res (1988) 0.84