Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S(1) pocket using conformationally constrained inhibitors.

Zinc-binding groups modulate selective inhibition of MMPs. ChemMedChem (2008) 1.47

Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors. Eur J Med Chem (2011) 0.82

Matrix metalloproteinase 9 (MMP-9) is indispensable for long term potentiation in the central and basal but not in the lateral nucleus of the amygdala. Front Cell Neurosci (2015) 0.78

Combined structure- and ligand-based pharmacophore modeling and molecular dynamics simulation studies to identify selective inhibitors of MMP-8. J Mol Model (2014) 0.76

N-Aryl sulfonyl homocysteine hydroxamate inhibitors of matrix metalloproteinases: further probing of the S(1), S(1)', and S(2)' pockets. J Med Chem (2001) 0.87

A comparative docking study and the design of potentially selective MMP inhibitors. J Comput Aided Mol Des (2001) 0.78

Elucidation of a common structure of selective fibrinogen receptor antagonists. J Comput Aided Mol Des (1998) 0.76

EDITORIAL: Advances in Computational Structure Based Drug Discovery. Curr Pharm Des (2013) 0.75