M Radman

Author PubWeight™ 171.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Proc Natl Acad Sci U S A 1980 10.16
2 The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 1989 8.15
3 Role of mutator alleles in adaptive evolution. Nature 1997 5.95
4 Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995 5.54
5 SOS repair hypothesis: phenomenology of an inducible DNA repair which is accompanied by mutagenesis. Basic Life Sci 1975 4.17
6 Repair of defined single base-pair mismatches in Escherichia coli. Proc Natl Acad Sci U S A 1985 3.88
7 Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut. Science 2001 3.76
8 Mismatch repair in Escherichia coli. Annu Rev Genet 1986 3.71
9 Highly variable mutation rates in commensal and pathogenic Escherichia coli. Science 1997 3.67
10 Induced mutagenesis in dam- mutants of Escherichia coli: a role for 6-methyladenine residues in mutation avoidance. Mol Gen Genet 1978 3.56
11 Interspecies gene exchange in bacteria: the role of SOS and mismatch repair systems in evolution of species. Cell 1995 3.30
12 Molecular keys to speciation: DNA polymorphism and the control of genetic exchange in enterobacteria. Proc Natl Acad Sci U S A 1997 2.90
13 Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. Proc Natl Acad Sci U S A 1994 2.84
14 Ultraviolet reactivation and ultraviolet mutagenesis of lambda in different genetic systems. Virology 1971 2.83
15 Evolutionary implications of the frequent horizontal transfer of mismatch repair genes. Cell 2000 2.72
16 Counteraction by MutT protein of transcriptional errors caused by oxidative damage. Science 1997 2.67
17 Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates. Proc Natl Acad Sci U S A 1978 2.48
18 cAMP-dependent SOS induction and mutagenesis in resting bacterial populations. Proc Natl Acad Sci U S A 1995 2.44
19 Control of large chromosomal duplications in Escherichia coli by the mismatch repair system. Genetics 1991 2.25
20 An endonuclease from Escherichia coli that introduces single polynucleotide chain scissions in ultraviolet-irradiated DNA. J Biol Chem 1976 2.23
21 Protein oxidation in response to increased transcriptional or translational errors. Proc Natl Acad Sci U S A 2000 2.14
22 Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability. Mol Gen Genet 1998 2.11
23 Replicational fidelity: mechanisms of mutation avoidance and mutation fixation. Cold Spring Harb Symp Quant Biol 1979 2.10
24 Indirect ultraviolet-reactivation of phage lambda. Proc Natl Acad Sci U S A 1974 2.09
25 GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair. EMBO J 1987 2.05
26 Repair of a mismatch is influenced by the base composition of the surrounding nucleotide sequence. Genetics 1987 2.03
27 Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA. J Biol Chem 1988 1.97
28 Involvement of Escherichia coli mismatch repair in DNA replication and recombination. Cold Spring Harb Symp Quant Biol 1984 1.92
29 Induction kinetics of mutagenic DNA repair activity in E. coli following ultraviolet irradiation. Mol Gen Genet 1976 1.88
30 The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors. EMBO J 1989 1.84
31 Molecular mechanisms of induced mutagenesis. Replication in vivo of bacteriophage phiX174 single-stranded, ultraviolet light-irradiated DNA in intact and irradiated host cells. J Mol Biol 1977 1.78
32 Mismatch repair of deaminated 5-methyl-cytosine. J Mol Biol 1987 1.77
33 Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift. Genes Dev 2001 1.76
34 To be a mutator, or how pathogenic and commensal bacteria can evolve rapidly. Trends Microbiol 1997 1.75
35 Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes. Proc Natl Acad Sci U S A 1992 1.64
36 Structures of mismatched base pairs in DNA and their recognition by the Escherichia coli mismatch repair system. EMBO J 1986 1.63
37 HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet 1999 1.59
38 Genetic barriers among bacteria. Trends Microbiol 1996 1.50
39 Mutation detection using immobilized mismatch binding protein (MutS). Nucleic Acids Res 1995 1.49
40 Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis. Proc Natl Acad Sci U S A 1978 1.49
41 Methyl-directed repair of frameshift mutations in heteroduplex DNA. Proc Natl Acad Sci U S A 1986 1.48
42 Effects of DNA methylation on mismatch repair, mutagenesis, and recombination in Escherichia coli. Curr Top Microbiol Immunol 1984 1.47
43 Mismatch repair and recombination in E. coli. Cell 1987 1.46
44 The rise and fall of mutator bacteria. Curr Opin Microbiol 2001 1.46
45 Saturation of mismatch repair in the mutD5 mutator strain of Escherichia coli. J Bacteriol 1989 1.42
46 GATC sequence and mismatch repair in Escherichia coli. EMBO J 1986 1.42
47 A mechanism for initiation of genetic recombination. Proc Natl Acad Sci U S A 1975 1.40
48 Mismatch-stimulated killing. Proc Natl Acad Sci U S A 1986 1.38
49 A system for detection of genetic and epigenetic alterations in Escherichia coli induced by DNA-damaging agents. J Mol Biol 1985 1.33
50 Mismatch repair involving localized DNA synthesis in extracts of Xenopus eggs. Proc Natl Acad Sci U S A 1989 1.30
51 DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA repair synthesis for all single base-pair mismatches. Proc Natl Acad Sci U S A 1990 1.30
52 Mutation, recombination, and incipient speciation of bacteria in the laboratory. Proc Natl Acad Sci U S A 1999 1.28
53 Mechanism and control of interspecies recombination in Escherichia coli. I. Mismatch repair, methylation, recombination and replication functions. Genetics 1998 1.26
54 SOS mutator effect in E. coli mutants deficient in mismatch correction. EMBO J 1984 1.25
55 Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I. J Bacteriol 1989 1.24
56 Genetic analysis of mutagenesis in aging Escherichia coli colonies. Mol Gen Genet 1997 1.22
57 Is there SOS induction in mammalian cells? Photochem Photobiol 1980 1.21
58 Genetic requirements for hyper-recombination by very short patch mismatch repair: involvement of Escherichia coli DNA polymerase I. Mol Gen Genet 1989 1.19
59 Radiation-induced base substitution mutagenesis in single-stranded DNA phage M13. Nature 1981 1.18
60 Enzymes of evolutionary change. Nature 1999 1.18
61 Involvement of DNA polymerase III in UV-induced mutagenesis of bacteriophage lambda. Mol Gen Genet 1985 1.15
62 Complementary action of recombination and excision in the repair of ultraviolet irradiation damage to DNA. J Mol Biol 1970 1.12
63 Enzymatic repair of DNA: SITES OF HYDROLYSIS BY THE Escherichia coli endonuclease specific for pyrimidine dimers (correndonuclease II). Biochemistry 1976 1.12
64 Recovery of phage lambda from ultraviolet damage. Basic Life Sci 1975 1.08
65 Large non-homology in heteroduplex DNA is processed differently than single base pair mismatches. Mol Gen Genet 1987 1.08
66 Conservation and diversification of genes by mismatch correction and SOS induction. Biochimie 1983 1.04
67 Evidence for an intermediate in DNA synthesis involving pyrophosphate exchange. A possible role in fidelity. J Mol Biol 1986 0.99
68 UV-reactivation of bacteriophage lambda in excision repair-deficient hosts: independence of red functions and attachment regions. Virology 1971 0.98
69 Inhibition of carcinogen-induced chromosomal aberrations by an anticarcinogenic protease inhibitor. Proc Natl Acad Sci U S A 1980 0.97
70 Highly mismatched molecules resembling recombination intermediates efficiently transform mismatch repair proficient Escherichia coli. Genetics 1997 0.96
71 Studies on the miscoding properties of 1,N6-ethenoadenine and 3,N4-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis. Nucleic Acids Res 1981 0.95
72 Counterselection of GATC sequences in enterobacteriophages by the components of the methyl-directed mismatch repair system. J Mol Evol 1991 0.93
73 Mismatch repair in Xenopus egg extracts: DNA strand breaks act as signals rather than excision points. Proc Natl Acad Sci U S A 1996 0.93
74 No genetic barriers between Salmonella enterica serovar typhimurium and Escherichia coli in SOS-induced mismatch repair-deficient cells. J Bacteriol 2000 0.92
75 Carcinogenesis. Missing mismatch repair. Nature 1994 0.91
76 Interspecific recombination between Escherichia coli and Salmonella typhimurium occurs by the RecABCD pathway. Biochimie 1991 0.90
77 Processing of mispaired and unpaired bases in heteroduplex DNA in E. coli. Biochimie 1986 0.89
78 Mutation rate of the f episome. Science 1995 0.89
79 Structure of recombinants from conjugational crosses between Escherichia coli donor and mismatch-repair deficient Salmonella typhimurium recipients. Genetics 1994 0.89
80 Chromosomal rearrangement and carcinogenesis. Mutat Res 1982 0.88
81 Phenomenological theory of repair kinetics of ultraviolet irradiated Lambda phage. Virology 1971 0.88
82 Mismatch-stimulated plasmid integration in yeast. Curr Genet 1991 0.87
83 Cloning and expression of the Xenopus and mouse Msh2 DNA mismatch repair genes. Nucleic Acids Res 1994 0.84
84 Genetic variability and adaptation to stress. EXS 1997 0.84
85 Enhanced efficiency of excision repair of non-replicated UV-damaged E. coli DNA. Mutat Res 1970 0.82
86 Pyrimidine dimer-induced enhancement of recombination among lambda bacteriophages. Virology 1970 0.82
87 Some restriction endonucleases tolerate single mismatches of the pyrimidine.purine type. Nucleic Acids Res 1990 0.80
88 Endonuclease III: an endonuclease from Escherichia coli that introduces single polynucleotide chain scissions in ultraviolet-irradiated DNA. Basic Life Sci 1975 0.80
89 recA-independent mutagenicity induced by chloroethylene oxide in E. coli. Mutat Res 1985 0.78
90 Mismatch repair in xenopus egg extracts is not strand-directed by DNA methylation. Neoplasma 2000 0.78
91 Interspecies recombination and mismatch repair. Generation of mosaic genes and genomes. Methods Mol Biol 2000 0.78
92 Induction of a stable, heritable epigenetic change by mutagenic carcinogens: a new test system. IARC Sci Publ 1980 0.77
93 Chromosomal events in carcinogenic initiation and promotion: implications for carcinogenicity testing and cancer prevention strategies. IARC Sci Publ 1980 0.75
94 Mutation rate of the F episome. Science 1995 0.75
95 Replication of chemically modified DNA. Biochimie 1978 0.75
96 [Synthesis of substituted benzoylacrylic acids as potential antagonists of phospholipase A2]. Pharmazie 1999 0.75
97 Inducible pathways in deoxyribonucleic acid repair, mutagenesis and carcinogenesis. Biochem Soc Trans 1977 0.75
98 Target size of DNA in ultraviolet irradiation. Nat New Biol 1971 0.75
99 Workshop on processing of DNA damage. Mutat Res 1996 0.75
100 Replication and mutagenesis of irradiated single-strand phage DNA. Basic Life Sci 1983 0.75
101 DNA damage, DNA repair and induced mutagenesis: some enzymological and structural considerations. Basic Life Sci 1986 0.75
102 [E-Z ratio and stability of halogenated benzylidene derivatives formed during the detection of glycine conjugates]. Pharmazie 2000 0.75
103 Mutagenesis and cell transformation by ultraviolet irradiation: many hypotheses for few results. Natl Cancer Inst Monogr 1978 0.75
104 Carcinogenic potency in rodents versus genotoxic potency in E. coli: a correlation analysis for bifunctional alkylating agents. Mutat Res 1987 0.75
105 [The repair of radioinduced pyrimidine dimers in lambda bacteriophage DNA: participation of Escherichia coli uvr and rec genes and lambda red gene]. Arch Int Physiol Biochim 1969 0.75
106 Protection and host cell repair of irradiated lambda phage. 3. Ultraviolet irradiation of 5-bromouracil-substituted phage. Mol Gen Genet 1969 0.75
107 [How much do we know about human brucellosis?]. Z Rheumatol 2009 0.75
108 Repair mechanisms involved in the recovery of phage lambda from ultraviolet damage. An Acad Bras Cienc 1973 0.75
109 Mutagenesis assays with bacteria. IARC Monogr Eval Carcinog Risk Chem Hum Suppl 1980 0.75
110 Protection and host cell repair of irradiated lambda phage. I. Irradiation of normal phage with ultraviolet light. Mol Gen Genet 1969 0.75
111 [Synthesis of lipophilic keto acids by acylation of alkylbenzenes as potential inhibitors of phospholipase A2]. Pharmazie 1998 0.75
112 Genotoxic potency of monofunctional alkylating agents in E. coli: comparison with carcinogenic potency in rodents. Mutat Res 1990 0.75
113 Protection and host cell repair of irradiated lambda phage. II. Irradiation of 5-bromouracil-substituted phage with near visible light. Mol Gen Genet 1969 0.75