Published in Environ Health Perspect on August 01, 2001
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev (2012) 6.12
An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2009) 1.44
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med (2014) 1.08
A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF. Toxicol Pathol (2007) 0.94
Persistent hematologic and immunologic disturbances in 8-year-old Dutch children associated with perinatal dioxin exposure. Environ Health Perspect (2003) 0.93
Role of AhR/ARNT system in skin homeostasis. Arch Dermatol Res (2014) 0.90
Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event? Biochem Pharmacol (2008) 0.90
Serum dioxin concentrations and age at menopause. Environ Health Perspect (2005) 0.89
Dioxin cancer risk--example of hormesis? Dose Response (2006) 0.83
Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells. BMC Syst Biol (2011) 0.82
Effect of chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rats on ovarian gene expression. Reprod Toxicol (2009) 0.82
The influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hematological parameters during experimentally induced pleuritis in rats. Inflammation (2013) 0.81
Advances in analytical techniques for polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs. Anal Bioanal Chem (2006) 0.79
Temporal and anatomical sensitivities to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin leading to premature acyclicity with age in rats. Int J Androl (2010) 0.79
Serum dioxin concentrations and quality of ovarian function in women of Seveso. Environ Health Perspect (2006) 0.77
Male and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. BMC Genomics (2015) 0.76
Histopathological, ultrastructural, and immunohistochemical assessment of hippocampus structures of rats exposed to TCDD and high doses of tocopherol and acetylsalicylic acid. Biomed Res Int (2015) 0.75
Dioxins: diagnostic and prognostic challenges arising from complex mechanisms. J Appl Toxicol (2012) 0.75
The Seveso studies on early and long-term effects of dioxin exposure: a review. Environ Health Perspect (1998) 1.72
Toxicology of chlorinated dibenzo-p-dioxins. Environ Health Perspect (1973) 1.59
Morbidity follow up study of BASF employees exposed to 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) after a 1953 chemical reactor incident. Occup Environ Med (1994) 1.57
Toxicology. Just how bad is dioxin? Science (2000) 1.47
Serum dioxin levels in Seveso, Italy, population in 1976. Teratog Carcinog Mutagen (1998) 1.39
Assessment of past occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin using blood lipid analyses. Int Arch Occup Environ Health (1993) 1.36
The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity. Crit Rev Toxicol (1994) 1.35
Laboratory results for selected target organs in 138 individuals occupationally exposed to TCDD. Chemosphere (1995) 1.35
Clinical laboratory manifestations of exposure to dioxin in children. A six-year study of the effects of an environmental disaster near Seveso, Italy. JAMA (1986) 1.32
A review of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: 1991 update. Toxicology (1991) 1.25
2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells. Proc Natl Acad Sci U S A (1990) 1.21
Chloracne, "the hallmark of dioxin intoxication". Scand J Work Environ Health (1985) 1.00
Review and update of the results of the NIOSH medical study of workers exposed to chemicals contaminated with 2,3,7,8-tetrachlorodibenzodioxin. Teratog Carcinog Mutagen (1998) 0.96
Gonadotropin-releasing hormone (GnRH) partially reverses the inhibitory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on ovulation in the immature gonadotropin-treated rat. Toxicology (2000) 0.89
Olestra increases faecal excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Lancet (1999) 0.89
A risk-benefit assessment of sulpiride in the treatment of schizophrenia. Drug Saf (1996) 0.86
2,3,7,8-tetrachlorodibenzo-p-dioxin decreases estradiol production without altering the enzyme activity of cytochrome P450 aromatase of human luteinized granulosa cells in vitro. Biol Reprod (2000) 0.86
Reflections on the assessment of the toxicity of "dioxins" for humans, using data from experimental and epidemiological studies. Teratog Carcinog Mutagen (1998) 0.84
Punctate keratoderma-like lesions on the palms and soles in a patient with chloracne: a new clinical manifestation of dioxin intoxication? Br J Dermatol (2000) 0.83
[Hyperprolactinemia]. Schweiz Med Wochenschr (1986) 0.79
Blood lipid concentrations of dioxins and dibenzofurans causing chloracne. Br J Dermatol (1999) 0.79
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am J Pathol (1999) 5.02
Zidovudine in persons with asymptomatic HIV infection and CD4+ cell counts greater than 400 per cubic millimeter. The European-Australian Collaborative Group. N Engl J Med (1993) 4.88
Immunologic functions of Ia-bearing epidermal Langerhans cells. J Immunol (1978) 4.55
Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med (2001) 3.74
Epidermal Langerhans cells--a target for HTLV-III/LAV infection. J Invest Dermatol (1987) 3.41
Epidermal Langerhans cells bear Fc and C3 receptors. Nature (1977) 3.21
Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION). Br J Dermatol (2007) 2.85
In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6). J Exp Med (1988) 2.81
Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. Cancer Res (1998) 2.60
Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8. J Virol (1997) 2.59
Origin and function of epidermal Langerhans cells. Immunol Rev (1980) 2.54
MDR1 gene expression and treatment outcome in acute myeloid leukemia. J Natl Cancer Inst (1991) 2.50
Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J Exp Med (1986) 2.45
Ultraviolet light depletes surface markers of Langerhans cells. J Invest Dermatol (1981) 2.28
Expression of Thy-1 antigen by murine epidermal cells. J Invest Dermatol (1983) 2.20
Desmoglein 3-ELISA: a pemphigus vulgaris-specific diagnostic tool. Arch Dermatol (1999) 2.19
Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol (1988) 2.17
Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly. AIDS Res Hum Retroviruses (1990) 2.15
Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines. Science (1987) 2.12
Productive dual infection of human CD4+ T lymphocytes by HIV-1 and HHV-6. Nature (1989) 1.96
The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells. J Exp Med (1985) 1.93
Detection of Ia antigens on Langerhans cells in guinea pig skin. J Immunol (1978) 1.90
A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3). J Immunol (1984) 1.90
Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells. J Exp Med (1999) 1.89
Epidermal cells adhere preferentially to type IV (basement membrane) collagen. J Cell Biol (1979) 1.86
Expression of functional high affinity immunoglobulin E receptors (Fc epsilon RI) on monocytes of atopic individuals. J Exp Med (1994) 1.85
Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI. J Exp Med (1992) 1.77
Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. Br J Dermatol (1999) 1.77
Guidelines for treatment of atopic eczema (atopic dermatitis) part I. J Eur Acad Dermatol Venereol (2012) 1.77
HIV-related skin diseases. Lancet (1996) 1.76
Evidence of HLA-DR antigen biosynthesis by human keratinocytes in disease. J Exp Med (1984) 1.75
GA(2)LEN skin test study I: GA(2)LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe. Allergy (2009) 1.72
Analogous functions of macrophages and Langerhans cells in the initiation in the immune response. J Invest Dermatol (1978) 1.71
Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi's sarcoma. Int J Cancer (1997) 1.65
Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells. Lab Invest (1999) 1.62
Antigen presentation by murine epidermal langerhans cells and its alteration by ultraviolet B light. J Immunol (1981) 1.60
Cyclosporin A suppresses ICAM-1 expression by papillary endothelium in healing psoriatic plaques. J Invest Dermatol (1991) 1.60
The high affinity IgE receptor (Fc epsilon RI) mediates IgE-dependent allergen presentation. J Immunol (1995) 1.59
Human epidermal T cells predominantly belong to the lineage expressing alpha/beta T cell receptor. J Exp Med (1990) 1.57
Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. J Exp Med (1998) 1.54
Ia antigens in mouse skin are predominantly expressed on Langerhans cells. J Immunol (1979) 1.53
The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J (2001) 1.53
GA(2)LEN skin test study II: clinical relevance of inhalant allergen sensitizations in Europe. Allergy (2009) 1.51
Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines. J Immunol (1999) 1.50
Guidelines for treatment of atopic eczema (atopic dermatitis) Part II. J Eur Acad Dermatol Venereol (2012) 1.49
Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain. Proc Natl Acad Sci U S A (1987) 1.48
Immunofluorescent detection of human B cell alloantigens on S-Ig-positive lymphocytes and epidermal Langerhans cells. J Immunol (1978) 1.47
Thy-1+ dendritic epidermal cells belong to the T-cell lineage. Proc Natl Acad Sci U S A (1987) 1.46
Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood (2000) 1.45
A comparative study on demographic, hematological, and cytogenetic findings and prognosis in acute myeloid leukemia with and without leukemia cutis. Ann Hematol (2002) 1.44
Further evidence for lymphokine overproduction in severe aplastic anemia. Blood (1988) 1.43
Upper keratinocytes of psoriatic skin lesions express high levels of NAP-1/IL-8 mRNA in situ. J Invest Dermatol (1991) 1.43
Generation of human dendritic cells/Langerhans cells from circulating CD34+ hematopoietic progenitor cells. Blood (1996) 1.42
ERCP and balloon dilation is a valuable alternative to surgical biliodigestive anastomosis in the long common channel syndrome in childhood. Endoscopy (1995) 1.40
Serum IgG autoantibodies directed against the alpha chain of Fc epsilon RI: a selective marker and pathogenetic factor for a distinct subset of chronic urticaria patients? J Clin Invest (1995) 1.40
[Retro- and prospective studies on the value of clinical and laboratory chemical data in acute appendicitis]. Chirurg (1990) 1.38
Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily. Eur J Clin Invest (2009) 1.32
Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma. Am J Pathol (1996) 1.30
Langerhans cells as stimulator cells in the murine primary epidermal cell-lymphocyte reaction: alteration by UV-B irradiation. J Invest Dermatol (1982) 1.30
Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation. J Immunol (1996) 1.30
Characterization of an HIV-1 point mutant blocked in envelope glycoprotein cleavage. Virology (1990) 1.27
Langerhans' cells are an actual site of HIV-1 replication. Intervirology (1988) 1.27
Endocarditis and aortal embolization caused by Aspergillus terreus in a patient with acute lymphoblastic leukemia in remission: diagnosis by peripheral-blood culture. J Clin Microbiol (1998) 1.24
Melanin binds reversibly to thermostable DNA polymerase and inhibits its activity. Biochem Biophys Res Commun (2000) 1.22
Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells. J Exp Med (2001) 1.21
Mechanism of UV-B-induced impairment of the antigen-presenting capacity of murine epidermal cells. J Immunol (1983) 1.20
Anti-FcepsilonRIalpha autoantibodies in autoimmune-mediated disorders. Identification of a structure-function relationship. J Clin Invest (1998) 1.19
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J Invest Dermatol (2000) 1.19
A skin homing molecule defines the langerhans cell progenitor in human peripheral blood. J Exp Med (1997) 1.18
[Epidemiology and clinical value of true umbilical cord knots]. Wien Klin Wochenschr (1998) 1.18
Immunofluorescence mapping of antigenic determinants within the dermal-epidermal junction in the mechanobullous diseases. J Invest Dermatol (1981) 1.17
Interleukin 2 receptors on cultured murine epidermal Langerhans cells. J Immunol (1986) 1.16
Leu-3/T4 expression on epidermal Langerhans cells in normal and diseased skin. J Invest Dermatol (1986) 1.16
Induction of Fc epsilon R2/CD23 on human epidermal Langerhans cells by human recombinant interleukin 4 and gamma interferon. J Exp Med (1989) 1.16
Regression of deeply infiltrating giant condyloma (Buschke-Löwenstein tumor) following long-term intralesional interferon alfa therapy. Arch Dermatol (2000) 1.15
Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma. Virology (1997) 1.15
MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions. J Invest Dermatol (1993) 1.15
CD34+ cell-derived CD14+ precursor cells develop into Langerhans cells in a TGF-beta 1-dependent manner. J Immunol (1999) 1.15
Vascular endothelial growth factor is constitutively expressed in normal human salivary glands and is secreted in the saliva of healthy individuals. J Pathol (1998) 1.15
The functional role of Langerhans cells. J Invest Dermatol (1980) 1.11
Vascular endothelial growth factor production in normal epidermis and in benign and malignant epithelial skin tumors. Lab Invest (1996) 1.11
Influence of the catechol-O-methyltransferase (COMT) codon 158 polymorphism on estrogen levels in women. Hum Reprod (2003) 1.11
1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro. Exp Hematol (2000) 1.10
Coexistence of lichen planus and bullous pemphigoid. A immunopathological study. Br J Dermatol (1975) 1.10
Human keratinocytes express the three major splice forms of vascular endothelial growth factor. J Invest Dermatol (1995) 1.09
Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression. Blood (1995) 1.07
Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem Biophys Res Commun (2000) 1.07
Maturational steps of bone marrow-derived dendritic murine epidermal cells. Phenotypic and functional studies on Langerhans cells and Thy-1+ dendritic epidermal cells in the perinatal period. J Immunol (1989) 1.07
The Langerhans cell. J Invest Dermatol (1983) 1.06