Published in Hypertension on September 01, 2001
Study MIPAE - Melatonin and Essential Arterial Hypertension (MIPAE) | NCT05257291
Pathway analysis of seven common diseases assessed by genome-wide association. Genomics (2008) 4.11
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest (2003) 2.68
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36
History of hypertension and eplerenone in patients with acute myocardial infarction complicated by heart failure. Hypertension (2008) 2.09
Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling. J Clin Invest (2005) 1.89
Intracranial aneurysms: from vessel wall pathology to therapeutic approach. Nat Rev Neurol (2011) 1.77
Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol (2008) 1.54
Mechanisms of arterial remodeling in hypertension: coupled roles of wall shear and intramural stress. Hypertension (2008) 1.52
Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling. Nat Commun (2015) 1.43
Fibronectin matrix turnover occurs through a caveolin-1-dependent process. Mol Biol Cell (2004) 1.40
Fibronectin is an important regulator of flow-induced vascular remodeling. Arterioscler Thromb Vasc Biol (2009) 1.40
Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cell Mol Neurobiol (2005) 1.39
Mechanical Stretch Inhibits MicroRNA499 via p53 to Regulate Calcineurin-A Expression in Rat Cardiomyocytes. PLoS One (2016) 1.38
Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction. Nat Med (2006) 1.27
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation (2008) 1.26
Blast-induced phenotypic switching in cerebral vasospasm. Proc Natl Acad Sci U S A (2011) 1.14
A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response. Lab Chip (2011) 1.13
Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation. Biomech Model Mechanobiol (2011) 1.13
Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1. Am J Physiol Regul Integr Comp Physiol (2009) 1.11
Doxycycline, a matrix metalloprotease inhibitor, reduces vascular remodeling and damage after cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol (2011) 1.10
Toll-like receptors and damage-associated molecular patterns: novel links between inflammation and hypertension. Am J Physiol Heart Circ Physiol (2013) 1.08
NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases. Redox Biol (2015) 1.08
Aging, metabolic syndrome and the heart. Aging Dis (2012) 1.07
Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension. Hypertension (2011) 1.06
Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol (2008) 1.04
MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin. J Cell Sci (2011) 1.02
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proc Natl Acad Sci U S A (2014) 1.01
Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia. Biomech Model Mechanobiol (2008) 0.99
Association between inflammatory marker, environmental lead exposure, and glutathione S-transferase gene. Biomed Res Int (2013) 0.99
Vascular wall extracellular matrix proteins and vascular diseases. Biochim Biophys Acta (2014) 0.99
Reactive oxygen species and vascular remodelling in hypertension: still alive. Can J Cardiol (2006) 0.98
Relations of matrix remodeling biomarkers to blood pressure progression and incidence of hypertension in the community. Circulation (2009) 0.97
Enhanced blood pressure variability in a high cardiovascular risk group of African Americans: FIT4Life Study. J Am Soc Hypertens (2010) 0.96
Angiotensin II AT1 receptor blockade decreases lipopolysaccharide-induced inflammation in the rat adrenal gland. Endocrinology (2008) 0.94
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Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes. Ann Epidemiol (2011) 0.93
Emerging roles of fibronectin in thrombosis. Thromb Res (2010) 0.92
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension. Br J Pharmacol (2010) 0.92
Classical Renin-Angiotensin system in kidney physiology. Compr Physiol (2014) 0.92
MicroRNA: A matter of life or death. World J Biol Chem (2010) 0.91
Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats. Cardiovasc Res (2015) 0.90
Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats. Clin Exp Pharmacol Physiol (2008) 0.87
Phenomics of cardiac chloride channels. Compr Physiol (2013) 0.86
Heme oxygenase-1 induced by aprotinin inhibits vascular smooth muscle cell proliferation through cell cycle arrest in hypertensive rats. Korean J Physiol Pharmacol (2009) 0.85
Middle cerebral artery alterations in a rat chronic hypoperfusion model. J Appl Physiol (1985) (2011) 0.85
Vascular actions of 20-HETE. Prostaglandins Other Lipid Mediat (2015) 0.85
Matrix Metalloproteinase Inhibition Mitigates Renovascular Remodeling in Salt-Sensitive Hypertension. Physiol Rep (2013) 0.85
Chloride channels in stroke. Acta Pharmacol Sin (2012) 0.84
Plasticity of TRPV1-Expressing Sensory Neurons Mediating Autonomic Dysreflexia Following Spinal Cord Injury. Front Physiol (2012) 0.84
Cardiovascular effects of losartan and its relevant clinical application. Curr Med Chem (2009) 0.84
A role for soluble ST2 in vascular remodeling associated with obesity in rats. PLoS One (2013) 0.83
20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension. Am J Physiol Renal Physiol (2013) 0.83
Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine. Br J Pharmacol (2007) 0.83
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Hemodynamics of cerebral aneurysms: computational analyses of aneurysm progress and treatment. Comput Math Methods Med (2012) 0.83
Synergistic vascular protective effects of combined low doses of PPARalpha and PPARgamma activators in angiotensin II-induced hypertension in rats. Br J Pharmacol (2007) 0.83
Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats. J Nutr Metab (2011) 0.83
Pyrrolidine dithiocarbamate down-regulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodelling in renovascular hypertension. Br J Pharmacol (2011) 0.83
MicroRNA-143/-145 in Cardiovascular Diseases. Biomed Res Int (2015) 0.83
SOD1 gene transfer into paraventricular nucleus attenuates hypertension and sympathetic activity in spontaneously hypertensive rats. Pflugers Arch (2012) 0.83
Skeletal Blood Flow in Bone Repair and Maintenance. Bone Res (2013) 0.83
The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats. BMC Complement Altern Med (2012) 0.82
Arterial wall stress controls NFAT5 activity in vascular smooth muscle cells. J Am Heart Assoc (2014) 0.82
Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice. J Hypertens (2013) 0.82
Improvement in middle cerebral artery structure and endothelial function in stroke-prone spontaneously hypertensive rats after macrophage depletion. Microcirculation (2013) 0.82
Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based study. Arthritis Care Res (Hoboken) (2012) 0.81
Collagen inhibitory peptide R1R2 mediates vascular remodeling by decreasing inflammation and smooth muscle cell activation. PLoS One (2015) 0.81
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Cystathionine gamma-lyase-deficient smooth muscle cells exhibit redox imbalance and apoptosis under hypoxic stress conditions. Exp Clin Cardiol (2011) 0.81
Short-term Mg deficiency upregulates protein kinase C isoforms in cardiovascular tissues and cells; relation to NF-kB, cytokines, ceramide salvage sphingolipid pathway and PKC-zeta: hypothesis and review. Int J Clin Exp Med (2014) 0.81
DNA Damage and Pulmonary Hypertension. Int J Mol Sci (2016) 0.81
Heterogeneity in arterial remodeling among sublines of spontaneously hypertensive rats. PLoS One (2014) 0.81
An emerging role of degrading proteinases in hypertension and the metabolic syndrome: autodigestion and receptor cleavage. Curr Hypertens Rep (2012) 0.81
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Volume matters: novel roles of the volume-regulated CLC-3 channels in hypertension-induced cerebrovascular remodeling. Hypertension (2010) 0.80
Aortic remodelling in chronic nicotine-administered rat. Korean J Physiol Pharmacol (2014) 0.80
Adaptation of mesenteric lymphatic vessels to prolonged changes in transmural pressure. Am J Physiol Heart Circ Physiol (2013) 0.80
Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide. Am J Physiol Heart Circ Physiol (2010) 0.80
Chronic Inflammatory Diseases and Endothelial Dysfunction. Aging Dis (2016) 0.80
Hypertension and genetic variation in endothelial-specific genes. PLoS One (2013) 0.80
Insulin Like Growth Factor Binding Protein-5 Regulates Excessive Vascular Smooth Muscle Cell Proliferation in Spontaneously Hypertensive Rats via ERK 1/2 Phosphorylation. Korean J Physiol Pharmacol (2013) 0.80
Constitutive description of human femoropopliteal artery aging. Biomech Model Mechanobiol (2016) 0.79
An exaggerated blood pressure response to exercise is associated with nitric oxide bioavailability and inflammatory markers in normotensive females. Hypertens Res (2016) 0.79
Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension. Braz J Med Biol Res (2014) 0.79
Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. J Hypertens (2014) 0.79
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging. Int J Clin Exp Med (2014) 0.79
Respiratory modulated sympathetic activity: a putative mechanism for developing vascular resistance? J Physiol (2015) 0.79
Involvement of inflammation and adverse vascular remodelling in the blood pressure raising effect of repeatedly heated palm oil in rats. Int J Vasc Med (2012) 0.79
Angiotensin-(1-7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK/ERK signaling pathways. Sci Rep (2016) 0.78
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension. Am J Physiol Regul Integr Comp Physiol (2015) 0.78
Ca2+, calmodulin, and cyclins in vascular smooth muscle cell cycle. Circ Res (2006) 0.78
Release of Matrix Metalloproteinases-2 and 9 by S-Nitrosylated Caveolin-1 Contributes to Degradation of Extracellular Matrix in tPA-Treated Hypoxic Endothelial Cells. PLoS One (2016) 0.77
Vascular dysfunction as target organ damage in animal models of hypertension. Int J Hypertens (2012) 0.77
Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films. J Vis Exp (2015) 0.77
Maternal Hyperleptinemia Is Associated with Male Offspring's Altered Vascular Function and Structure in Mice. PLoS One (2016) 0.77
Arsenic alters vascular smooth muscle cell focal adhesion complexes leading to activation of FAK-src mediated pathways. Toxicol Appl Pharmacol (2008) 0.77
Disturbed shear stress reduces Klf2 expression in arterial-venous fistulae in vivo. Physiol Rep (2015) 0.77
Endogenous Sulfur Dioxide: A New Member of Gasotransmitter Family in the Cardiovascular System. Oxid Med Cell Longev (2015) 0.77
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Structure and mechanical properties of resistance arteries in hypertension: role of adhesion molecules and extracellular matrix determinants. Hypertension (2000) 1.63
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Twisting integrin receptors increases endothelin-1 gene expression in endothelial cells. Am J Physiol Cell Physiol (2001) 1.34
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p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II. Arterioscler Thromb Vasc Biol (2004) 1.26
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Small artery remodeling is the most prevalent (earliest?) form of target organ damage in mild essential hypertension. J Hypertens (2001) 1.11
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