Published in J Cell Biol on October 01, 2001
Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc Natl Acad Sci U S A (2003) 2.80
Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages. Infect Immun (2003) 2.34
A novel role for phagocytosis-like uptake in herpes simplex virus entry. J Cell Biol (2006) 2.18
The uniformity of phagosome maturation in macrophages. J Cell Biol (2004) 2.13
PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation. J Exp Med (2008) 2.02
Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. PLoS Pathog (2006) 1.94
Mycobacterium tuberculosis phagosome maturation arrest: mycobacterial phosphatidylinositol analog phosphatidylinositol mannoside stimulates early endosomal fusion. Mol Biol Cell (2003) 1.61
PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking. Blood (2010) 1.37
Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation. J Exp Med (2002) 1.30
A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox. Mol Biol Cell (2006) 1.14
Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate. J Am Chem Soc (2006) 1.05
Evidence of Brucella abortus OPS dictating uptake and restricting NF-kappaB activation in murine macrophages. Microbes Infect (2008) 0.97
Leukotrienes target F-actin/cofilin-1 to enhance alveolar macrophage anti-fungal activity. J Biol Chem (2011) 0.92
Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation. BMC Clin Pathol (2003) 0.87
Synthesis and molecular recognition of phosphatidylinositol-3-methylenephosphate. Org Lett (2006) 0.86
A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection. PLoS Comput Biol (2012) 0.86
Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation. Mol Cell Proteomics (2014) 0.80
SNX3 recruits to phagosomes and negatively regulates phagocytosis in dendritic cells. Immunology (2013) 0.78
How antibodies alter the cell entry pathway of dengue virus particles in macrophages. Sci Rep (2016) 0.77
A Journey of Cytolethal Distending Toxins through Cell Membranes. Front Cell Infect Microbiol (2016) 0.75
Sensing of micropillars by osteoblasts involves complex intracellular signaling. J Mater Sci Mater Med (2017) 0.75
Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem (2001) 8.47
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature (1998) 7.92
A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J Cell Biol (1996) 5.52
Mycobacterium tuberculosis: here today, and here tomorrow. Nat Rev Mol Cell Biol (2001) 4.91
Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nat Cell Biol (1999) 4.76
Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J Cell Biol (1994) 4.26
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J Cell Biol (2001) 3.63
Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J Cell Biol (2001) 3.14
Trafficking and release of mycobacterial lipids from infected macrophages. Traffic (2000) 2.65
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat Cell Biol (2001) 2.39
Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis. J Cell Biol (2001) 2.28
Controlling the maturation of pathogen-containing vacuoles: a matter of life and death. Nat Cell Biol (1999) 2.17
The Rab5 effector EEA1 interacts directly with syntaxin-6. J Biol Chem (1999) 1.98
Phosphatidylinositol 3-phosphate is generated in phagosomal membranes. Curr Biol (2001) 1.49
How accurately can we image inositol lipids in living cells? Trends Pharmacol Sci (2000) 1.47
Mycobacterium tuberculosis H37Rv parietal and cellular lipoarabinomannans. Characterization of the acyl- and glyco-forms. J Biol Chem (2000) 1.20
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells. Curr Biol (2001) 1.14
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature (1998) 7.92
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J (2000) 7.48
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif. J Biol Chem (1995) 5.45
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell (1997) 4.68
FYVE fingers bind PtdIns(3)P. Nature (1998) 3.91
Rab GTPases in vesicular transport. Curr Opin Cell Biol (1993) 3.59
The role of phosphoinositides in membrane transport. Curr Opin Cell Biol (2001) 3.57
Hrs recruits clathrin to early endosomes. EMBO J (2001) 2.82
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J Biol Chem (1993) 2.62
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol (1994) 2.50
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes. J Cell Sci (2001) 2.48
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells. Plant Cell (2001) 2.28
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5. EMBO J (1998) 2.20
The Rab5 effector EEA1 interacts directly with syntaxin-6. J Biol Chem (1999) 1.98
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J Cell Biol (2003) 1.90
Phosphoinositides in membrane traffic. Curr Opin Cell Biol (1999) 1.90
Role of Rab GTPases in membrane traffic. Int Rev Cytol (1997) 1.84
Syntaxin-16, a putative Golgi t-SNARE. Eur J Cell Biol (1998) 1.83
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. J Cell Biol (1998) 1.74
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J (2001) 1.62
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues. J Biol Chem (2000) 1.58
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages. J Cell Sci (2000) 1.55
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion. EMBO J (1998) 1.51
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate. Mol Cell Biol (2000) 1.49
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis. Neuron (1994) 1.38
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer. Biochem J (1999) 1.30
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway. J Cell Sci (1995) 1.20
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions. J Biol Chem (1991) 1.15
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells. Curr Biol (2001) 1.14
Entry of ADP-ribosylating toxins into cells. Curr Top Microbiol Immunol (1992) 1.13
PX domains: attracted by phosphoinositides. Nat Cell Biol (2001) 1.13
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes. Eur J Cell Biol (1997) 1.11
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis. Oncogene (2011) 1.06
Diphtheria toxin entry: protein translocation in the reverse direction. Trends Biochem Sci (1988) 1.02
The role of ALFY in selective autophagy. Cell Death Differ (2012) 1.00
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor. Biochem J (1998) 1.00
Function of Hrs in endocytic trafficking and signalling. Biochem Soc Trans (2001) 1.00
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants. EMBO J (1989) 0.99
Direct interaction of EEA1 with Rab5b. Eur J Biochem (1999) 0.97
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate. Chem Phys Lipids (1999) 0.96
Protein targeting to endosomes and phagosomes via FYVE and PX domains. Curr Top Microbiol Immunol (2004) 0.96
Entry of diphtheria toxin-protein A chimeras into cells. J Biol Chem (1991) 0.94
Autoantibodies to a novel early endosome antigen 1. Clin Immunol Immunopathol (1998) 0.93
Cell biology. A lipid oils the endocytosis machine. Science (2001) 0.91
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic. Cold Spring Harb Symp Quant Biol (1995) 0.91
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking. Oncogene (2012) 0.89
Membrane translocation of diphtheria toxin carrying passenger protein domains. Infect Immun (1992) 0.89
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes. J Biol Chem (1989) 0.85
Protein toxins with intracellular targets. Microb Pathog (1990) 0.83
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region. Biochemistry (1993) 0.83
Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. J Struct Biol (2006) 0.80
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate. Biochem Soc Trans (1999) 0.80
[Health nurse in assistance to underdeveloped countries]. Sykepleien (1977) 0.75
[This is my fondest memory. Obedience before everything]. Sykepleien (1987) 0.75
[Cadmium in kidneys of Danes. II]. Ugeskr Laeger (1977) 0.75
[Can dental research be objective?]. Tandlaegebladet (1974) 0.75
[With raised flag: opening of nurse instructor studies at the University of Tromsø on August 22, 1977]. Sykepleien (1977) 0.75
[Nursing assistants' education in more advanced schools]. Sykepleien (1981) 0.75
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels. J Physiol (Paris) (1990) 0.75
[Anatomy in another way]. Dens Sapiens (1970) 0.75
[Nursing instructor education in Tromsø]. Sykepleien (1976) 0.75
[Visit to Kenya's nursing association]. Sykepleien (1977) 0.75
[Dental student inquiry 1971]. Dens Sapiens (1974) 0.75
[Utilization of a regular youth dental care scheme for those of birth year 1951 or 1952 in Korsor county]. Tandlaegebladet (1972) 0.75