PubRank

A Y Rudensky

Author PubWeight™ 38.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science 1998 3.98
2 Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity 1997 2.46
3 Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity 1999 2.14
4 Monoclonal antibody detection of a major self peptide. MHC class II complex. J Immunol 1992 1.94
5 Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol 2001 1.87
6 Major histocompatibility complex class II compartments in human and mouse B lymphoblasts represent conventional endocytic compartments. J Cell Biol 1997 1.75
7 Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes. J Immunol 2000 1.55
8 In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. Eur J Immunol 2001 1.48
9 The role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation. Immunol Rev 1999 1.37
10 Altered antigen presentation in mice lacking H2-O. Immunity 1998 1.36
11 Requirement for diverse, low-abundance peptides in positive selection of T cells. Science 1999 1.36
12 Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands. J Exp Med 2001 1.33
13 The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology. Curr Top Microbiol Immunol 2005 1.13
14 Competition for specific intrathymic ligands limits positive selection in a TCR transgenic model of CD4+ T cell development. J Immunol 2000 1.05
15 Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis. J Immunol 2001 0.99
16 Assembly of an abundant endogenous major histocompatibility complex class II/peptide complex in class II compartments. Eur J Immunol 1997 0.98
17 Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo. J Exp Med 1998 0.94
18 Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. Proc Natl Acad Sci U S A 1998 0.94
19 Variation in HLA-DM expression influences conversion of MHC class II alpha beta:class II-associated invariant chain peptide complexes to mature peptide-bound class II alpha beta dimers in a normal B cell line. J Immunol 1996 0.91
20 Immunoglobulin-specific T-B cell interaction. II. T cell clones recognize the processed form of B cells' own surface immunoglobulin in the context of the major histocompatibility complex class II molecule. Eur J Immunol 1989 0.90
21 Trypanosoma cruzi-infected macrophages are defective in major histocompatibility complex class II antigen presentation. Eur J Immunol 1997 0.89
22 Phenotype and function of CD4+ T cells in mice lacking invariant chain. J Immunol 1996 0.88
23 Mtv-1 superantigen trafficks independently of major histocompatibility complex class II directly to the B-cell surface by the exocytic pathway. J Virol 1998 0.87
24 Differential expression of CLIP:MHC class II and conventional endogenous peptide:MHC class II complexes by thymic epithelial cells and peripheral antigen-presenting cells. Eur J Immunol 1996 0.85
25 Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proc Natl Acad Sci U S A 1996 0.82
26 An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II alphabeta dimers and facilitates highly efficient peptide loading. Int Immunol 1998 0.81
27 Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines. Eur J Immunol 1997 0.80
28 Peptide loading in the endoplasmic reticulum accelerates trafficking of peptide:MHC class II complexes in B cells. J Biomed Sci 1999 0.80
29 Immunoglobulin-specific T-B cell interaction. III. B cell activation by immunoglobulin-recognizing T cell clones. Eur J Immunol 1990 0.80
30 Evaluating peptide repertoires within the context of thymocyte development. Semin Immunol 1999 0.80