Published in Bioorg Med Chem Lett on October 22, 2001
Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update. Hepatol Res (2012) 1.24
The discovery and development of sorafenib for the treatment of thyroid cancer. Expert Opin Drug Discov (2015) 0.82
Personalizing colon cancer therapeutics: targeting old and new mechanisms of action. Pharmaceuticals (Basel) (2013) 0.81
A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity. Medchemcomm (2012) 0.79
Synthetic studies toward aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics. J Org Chem (2005) 0.75
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell (1987) 14.62
Indicators of life-threatening malaria in African children. N Engl J Med (1995) 13.17
Fingerprinting Candida albicans. J Immunol Methods (1986) 6.90
Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature (1987) 6.76
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
Impacts of urbanization on stream habitat and fish across multiple spatial scales. Environ Manage (2001) 5.65
A 10-year review of a minimally invasive technique for the correction of pectus excavatum. J Pediatr Surg (1998) 4.96
Customized growth curves for identification of large-for-gestational age neonates in pre-eclamptic women. Ultrasound Obstet Gynecol (2014) 4.86
Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med (1989) 4.40
Critical period effects in second language learning: the influence of maturational state on the acquisition of English as a second language. Cogn Psychol (1989) 4.27
T-cell responses to Mls and to bacterial proteins that mimic its behavior. Immunol Rev (1989) 3.80
The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors. Genes Dev (1991) 3.33
Biocompatible surfactants for water-in-fluorocarbon emulsions. Lab Chip (2008) 3.28
A role for bacteriophages in the evolution and transfer of bacterial virulence determinants. Mol Microbiol (1995) 3.24
Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device. AJNR Am J Neuroradiol (2010) 3.08
Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood. J Infect Dis (1998) 2.98
Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus. Am J Hum Genet (1988) 2.88
Outbreak of systemic Candida albicans in intensive care unit caused by cross infection. Br Med J (Clin Res Ed) (1985) 2.74
Genetic analysis of IDDM: the GAW5 multiplex family dataset. Genet Epidemiol (1989) 2.73
The B cell is the initiating antigen-presenting cell in peripheral lymph nodes. J Immunol (1987) 2.55
Brevetoxin concentrations in marine aerosol: human exposure levels during a Karenia brevis harmful algal bloom. Bull Environ Contam Toxicol (2003) 2.53
Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin Pharmacol Ther (2007) 2.52
Diabetes mellitus associated with cystic fibrosis. J Pediatr (1988) 2.32
Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. Genome Res (1997) 2.17
Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil. Lancet (1998) 2.06
Biological properties of a CD4 immunoadhesin. Nature (1990) 2.05
Dental injury after conventional direct laryngoscopy: a prospective observational study. Anaesthesia (2013) 2.03
The histocompatibility system in juvenile, insulin-dependent diabetic multiplex kindreds. J Clin Invest (1977) 2.01
The cost-effectiveness of improving malaria home management: shopkeeper training in rural Kenya. Health Policy Plan (2006) 1.95
Homozygous parent affected sib pair method for detecting disease predisposing variants: application to insulin dependent diabetes mellitus. Genet Epidemiol (1993) 1.91
Imidotitanium complexes as hydroamination catalysts: substantially enhanced reactivity from an unexpected cyclopentadienide/amide ligand exchange. J Am Chem Soc (2001) 1.90
Linkage analysis between the major histocompatibility system and insulin-dependent diabetes in families with patients in two consecutive generations. J Clin Invest (1980) 1.90
Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases. J Bacteriol (1991) 1.82
State mental health policy: shifting resources to the community: closing the Illinois State Psychiatric Hospital for Adolescents in Chicago. Psychiatr Serv (2001) 1.81
High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas. Int J Cancer (1989) 1.79
A whole-genome radiation hybrid panel for bovine gene mapping. Mamm Genome (1997) 1.77
Central hemodynamic assessment of normal term pregnancy. Am J Obstet Gynecol (1989) 1.71
Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models. J Thromb Haemost (2012) 1.71
Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis. Proc Natl Acad Sci U S A (1987) 1.70
Effect of cyclophosphamide upon the immune response in Wegener's granulomatosis. N Engl J Med (1971) 1.70
Practice guidelines for performance of the routine mid-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol (2011) 1.66
Breast cancer diagnosis by screening mammography: early results of the Central Sydney Area Health Service Breast X-ray Programme. Med J Aust (1991) 1.64
Role of magnesium in the enzyme-linked immunosorbent assay for lipopolysaccharides of rough Escherichia coli strain J5 and Neisseria gonorrhoeae. J Infect Dis (1980) 1.64
Stimulus generalization as a function of discrimination learning with and without errors. Science (1969) 1.62
Rheumatoid factor-producing cells detected by direct hemolytic plaque assay. J Clin Invest (1976) 1.62
Complement fixation by rheumatoid factor. J Clin Invest (1975) 1.60
A universal driver of macroevolutionary change in the size of marine phytoplankton over the Cenozoic. Proc Natl Acad Sci U S A (2007) 1.59
Use of aminotransferase, hepatitis C antibody, and hepatitis C polymerase chain reaction RNA assays to establish the diagnosis of hepatitis C virus infection in a diagnostic virology laboratory. J Clin Microbiol (1992) 1.59
Altered lymphocyte reactivity in rheumatoid arthritis. Arthritis Rheum (1976) 1.58
Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. J Med Chem (1999) 1.56
A follow-up report of occupational stress in urban EMT-paramedics. Ann Emerg Med (1989) 1.54
Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo. Cancer Res (1986) 1.54
Epileptic seizures and malaria in Kenyan children. Trans R Soc Trop Med Hyg (1996) 1.53
Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis. Arthritis Rheum (1973) 1.53
Simulated workplace protection factor study of powered air-purifying and supplied air respirators. AIHAJ (2001) 1.52
Autocrine growth inhibition of a cloned line of helper T cells. Proc Natl Acad Sci U S A (1986) 1.51
B cells and antibodies in CNS demyelinating disease. J Neuroimmunol (2001) 1.50
Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation. Proc Natl Acad Sci U S A (1988) 1.49
Marital status, life-strains and depression. Am Sociol Rev (1977) 1.48
Experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to humans in rural housing. Am J Trop Med Hyg (1997) 1.47
Trial of an attenuated bovine rotavirus vaccine (RIT 4237) in Gambian infants. Lancet (1987) 1.47
The use of inversion mode and 3D manual segmentation in volume measurement of fetal fluid-filled structures: comparison with Virtual Organ Computer-aided AnaLysis (VOCAL). Ultrasound Obstet Gynecol (2008) 1.45
Identification of a gene encoding a bacteriophage-related integrase in a vap region of the Dichelobacter nodosus genome. Gene (1995) 1.45
European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication. Endoscopy (2012) 1.44
Cardiac output responses of primigravid women during exercise determined by the direct Fick technique. Obstet Gynecol (1990) 1.44
Trial of high-dose Edmonston-Zagreb measles vaccine in the Gambia: antibody response and side-effects. Lancet (1988) 1.41
Patient experiences with multiband full dynamic range compression. Ear Hear (1992) 1.41
Angiogenesis in the mouse lung. Am J Pathol (2000) 1.38
Analysis of linkage between the major histocompatibility system and juvenile, insulin-dependent diabetes in multiplex families. Reanalysis of data. J Clin Invest (1978) 1.38
Superficial tinea infections. Am Fam Physician (1993) 1.38
Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. J Virol (1989) 1.38
Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage. Proc Natl Acad Sci U S A (1991) 1.37
Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry. Blood (1991) 1.36
Effect of diclofenac sodium on the arachidonic acid cascade. Am J Med (1986) 1.36
Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. Proc Natl Acad Sci U S A (1987) 1.35
ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart. Ultrasound Obstet Gynecol (2013) 1.35
High-level transcription from the adenovirus major late promoter requires downstream binding sites for late-phase-specific factors. J Virol (1990) 1.34
Crescentic glomerulonephritis: a possible complication of streptokinase treatment for myocardial infarction. Br Heart J (1986) 1.33
Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA (1999) 1.32
Identification of a native Dichelobacter nodosus plasmid and implications for the evolution of the vap regions. Gene (1996) 1.32
Canine immunoglobulins. I. Evidence for six immunoglobulin classes. J Immunol (1967) 1.31
Immunological focusing by th mouse major histocompatibility complex: mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes. Eur J Immunol (1982) 1.29
A follow up model for patients with atrophic chronic gastritis and intestinal metaplasia. J Clin Pathol (2004) 1.29
Hypogammaglobulinemia associated with accelerated catabolism of IgG secondary to its inteaction with an IgG-reactive monoclonal IgM. J Clin Invest (1971) 1.29
The relationship between antibody affinity and the efficiency of complement fixation. J Immunol (1970) 1.28
Serological comparisons of approaches to polio vaccination in the Gambia. Lancet (1987) 1.28
The immunobiology of the T cell response to Mls-locus-disparate stimulator cells. I. Unidirectionality, new strain combinations, and the role of Ia antigens. J Immunol (1985) 1.28
The immunobiology of T cell responses to Mls-locus-disparate stimulator cells. III. Helper and cytolytic functions of cloned, Mls-reactive T cell lines. J Immunol (1986) 1.27
Inhibition of the expression of inducible cyclooxygenase and proinflammatory cytokines by sesquiterpene lactones in macrophages correlates with the inhibition of MAP kinases. Biochem Biophys Res Commun (1996) 1.27
The small GTP-binding protein Rho1p is localized on the Golgi apparatus and post-Golgi vesicles in Saccharomyces cerevisiae. J Cell Biol (1991) 1.26
Detergent-solubilization, purification, and characterization of membrane-bound 3-hydroxy-3-methylglutaryl-coenzyme A reductase from radish seedlings. Eur J Biochem (1986) 1.26
Translation of c-myc mRNA is required for its post-transcriptional regulation during myogenesis. J Biol Chem (1990) 1.25
Meningococcal disease in New York City, 1973 to 1978. Recognition of groups y and W-135 as frequent pathogens. JAMA (1980) 1.25
Heterozygous expression of insulin-dependent diabetes mellitus (IDDM) determinants in the HLA system. Am J Hum Genet (1983) 1.25
Prenatal diagnosis of membranous ventricular septal aneurysms and their association with absence of atrioventricular valve 'offsetting'. Ultrasound Obstet Gynecol (2004) 1.25
Clonal restriction of the immune response to phosphorylcholine. Nature (1974) 1.25
Chronic salicylate poisoning and severe malaria. Lancet (1996) 1.25
In vivo measurement of lung volumes in mice. Physiol Genomics (2001) 1.25
Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves. Am J Physiol Heart Circ Physiol (2008) 1.23
Altered expression of the RON receptor tyrosine kinase in various epithelial cancers and its contribution to tumourigenic phenotypes in thyroid cancer cells. J Pathol (2007) 1.23