PubRank

J M Wurtz

Author PubWeight™ 30.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The bromodomain revisited. Trends Biochem Sci 1997 2.95
2 The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand. Mol Cell 2000 2.77
3 Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. Mol Cell 2000 2.33
4 The TBP-like factor: an alternative transcription factor in metazoa? Trends Biochem Sci 1999 1.33
5 A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers. EMBO J 1997 1.30
6 X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. EMBO J 2001 1.27
7 Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J 1996 1.22
8 Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands. Proc Natl Acad Sci U S A 2001 1.20
9 Specific recognition of androgens by their nuclear receptor. A structure-function study. J Biol Chem 2000 1.16
10 Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism. J Biol Chem 2001 1.15
11 A canonical structure for the ligand-binding domain of nuclear receptors. Nat Struct Biol 1996 1.12
12 Antagonism in the human mineralocorticoid receptor. EMBO J 1998 1.08
13 The structure of cyclin H: common mode of kinase activation and specific features. EMBO J 1997 1.08
14 A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita. Mol Endocrinol 1997 1.02
15 Estrogen receptor transcription and transactivation: Structure-function relationship in DNA- and ligand-binding domains of estrogen receptors. Breast Cancer Res 2000 1.01
16 Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem Biol 1999 0.99
17 Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor. Mol Cell Biol 1999 0.95
18 Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties. Mol Cell Biol 1999 0.91
19 Different ligands-different receptor conformations: modeling of the hER alpha LBD in complex with agonists and antagonists. Med Res Rev 2001 0.83
20 A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones. Mol Pharmacol 2000 0.81
21 Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity. Mol Endocrinol 2000 0.81
22 Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor. Mol Endocrinol 2000 0.81
23 Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities. J Mol Endocrinol 1997 0.81
24 Amino acids specifying MHC class preference in TCR V alpha 2 regions. J Immunol 1999 0.79
25 Investigation of the binding interactions of progesterone using muteins of the human progesterone receptor ligand binding domain designed on the basis of a three-dimensional protein model. Biochim Biophys Acta 1999 0.78
26 Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity. Crit Rev Biochem Mol Biol 1998 0.78