Published in J Org Chem on March 08, 1996
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Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase. J Med Chem (2010) 1.15
Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis. Biochemistry (2008) 1.11
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Human- and plant-pathogenic Pseudomonas species produce bacteriocins exhibiting colicin M-like hydrolase activity towards peptidoglycan precursors. J Bacteriol (2009) 1.09
Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase. J Biol Chem (2008) 1.08
Deciphering the catalytic domain of colicin M, a peptidoglycan lipid II-degrading enzyme. J Biol Chem (2010) 1.05
Aslfm, the D-aspartate ligase responsible for the addition of D-aspartic acid onto the peptidoglycan precursor of Enterococcus faecium. J Biol Chem (2006) 1.04
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Functional and biochemical analysis of the Chlamydia trachomatis ligase MurE. J Bacteriol (2009) 0.98
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The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity. J Biol Chem (2006) 0.97
Biochemical characterisation of the chlamydial MurF ligase, and possible sequence of the chlamydial peptidoglycan pentapeptide stem. Arch Microbiol (2012) 0.96
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase. J Mol Biol (2007) 0.95
Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach. Bioorg Med Chem Lett (2009) 0.92
Fluorescence detection-based functional assay for high-throughput screening for MraY. Antimicrob Agents Chemother (2004) 0.92
Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme. J Med Chem (2008) 0.92
Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. J Bacteriol (2007) 0.92
5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases. ChemMedChem (2010) 0.91
Biochemical disclosure of the mycolate outer membrane of Corynebacterium glutamicum. J Bacteriol (2011) 0.89
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MurC and MurD synthetases of peptidoglycan biosynthesis: borohydride trapping of acyl-phosphate intermediates. Methods Enzymol (2002) 0.89
Functional and structural characterization of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa. J Biol Chem (2012) 0.89
Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF. Bioorg Chem (2009) 0.88
The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance. Mol Microbiol (2013) 0.88
Quantitative high-performance liquid chromatography analysis of the pool levels of undecaprenyl phosphate and its derivatives in bacterial membranes. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.88
Peptidoglycan precursor pools associated with MraY and FtsW deficiencies or antibiotic treatments. FEMS Microbiol Lett (2005) 0.87
Purification and biochemical characterization of Mur ligases from Staphylococcus aureus. Biochimie (2010) 0.87
A detailed study of the amino acids produced from the vacuum UV irradiation of interstellar ice analogs. Orig Life Evol Biosph (2008) 0.86
X-ray structure and site-directed mutagenesis analysis of the Escherichia coli colicin M immunity protein. J Bacteriol (2010) 0.85
Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening. Bioorg Med Chem (2009) 0.85
Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD. Bioorg Med Chem Lett (2005) 0.84
Colicin M hydrolyses branched lipids II from Gram-positive bacteria. Biochimie (2011) 0.84
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation. Eur J Med Chem (2011) 0.84
Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis. Biochimie (2007) 0.84
Glycosyl transferase activity of the Escherichia coli penicillin-binding protein 1b: specificity profile for the substrate. Biochemistry (2006) 0.83
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD). J Med Chem (2011) 0.83
Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid. Eur J Med Chem (2011) 0.83
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The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors. Angew Chem Int Ed Engl (2013) 0.82
Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers. Anal Biochem (2009) 0.82
Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity. Innate Immun (2013) 0.82
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Biochemical characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM 4136(T.). PLoS One (2013) 0.81
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase. Bioorg Med Chem Lett (2008) 0.80
Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF. Eur J Med Chem (2013) 0.80
Virtual screening for potential inhibitors of bacterial MurC and MurD ligases. J Mol Model (2011) 0.80
Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of MurC and MurD as potential antibacterial agents. Molecules (2008) 0.79
Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis. Microb Drug Resist (2012) 0.79
MurD enzymes from different bacteria: evaluation of inhibitors. Biochem Pharmacol (2012) 0.79
The GTPase CpgA is implicated in the deposition of the peptidoglycan sacculus in Bacillus subtilis. J Bacteriol (2008) 0.79
Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting D-Glu- and diphosphate-binding sites. Eur J Med Chem (2011) 0.79
MurD enzymes: some recent developments. Biomol Concepts (2013) 0.78
The elucidation of the structure of Thermotoga maritima peptidoglycan reveals two novel types of cross-link. J Biol Chem (2009) 0.78
Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase. Chemistry (2012) 0.77
Design, Synthesis and in vitro Biochemical Activity of Novel Amino Acid Sulfonohydrazide Inhibitors of MurC. Acta Chim Slov (2011) 0.76
Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases. ChemMedChem (2008) 0.76
Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. J Biol Chem (2013) 0.76
Discovery of the first inhibitors of bacterial enzyme D-aspartate ligase from Enterococcus faecium (Aslfm). Eur J Med Chem (2013) 0.76
The binding mode of second-generation sulfonamide inhibitors of MurD: clues for rational design of potent MurD inhibitors. PLoS One (2012) 0.76
Biochemical characterization of MurF from Streptococcus pneumoniae and the identification of a new MurF inhibitor through ligand-based virtual screening. Acta Chim Slov (2013) 0.75
Design and Synthesis of New Peptidomimetics as Potential Inhibitors of MurE. Acta Chim Slov (2011) 0.75
Enantioselective synthesis of α-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycan. Org Biomol Chem (2014) 0.75
Crystallization and preliminary X-ray analysis of Weissella viridescens FemX UDP-MurNAc-pentapeptide:l-alanine ligase. Acta Crystallogr D Biol Crystallogr (2003) 0.75
Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl). Biochimie (2012) 0.75
Purification and biochemical characterisation of GlmU from Yersinia pestis. Arch Microbiol (2014) 0.75