A novel liposomal influenza vaccine (INFLUSOME-VAC) containing hemagglutinin-neuraminidase and IL-2 or GM-CSF induces protective anti-neuraminidase antibodies cross-reacting with a wide spectrum of influenza A viral strains.

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Published in Vaccine on November 12, 2001

Authors

I Babai1, Y Barenholz, Z Zakay-Rones, E Greenbaum, S Samira, I Hayon, M Rochman, E Kedar

Author Affiliations

1: Hadassah Medical School, The Lautenberg Center for General and Tumor Immunology, Hebrew University, P.O. Box 12272, Jerusalem 91120, Israel.

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Sphingomyelins in bilayers and biological membranes. Biochim Biophys Acta (1980) 2.07

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Nomenclature for synthetic gene delivery systems. Hum Gene Ther (1997) 1.44

Interaction of trachoma elementary bodies with host cells. Isr J Med Sci (1969) 1.43

Rifampicin--a new antitrachoma drug. Nature (1969) 1.43

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Cellular immunoadsorbents: a simplified technique for separation of lymphoid cell populations. J Immunol (1974) 1.34

Changes in transmitter release induced by ion-containing liposomes. Proc Natl Acad Sci U S A (1978) 1.34

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Monolayer coupling in sphingomyelin bilayer systems. Nature (1978) 1.26

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Liposomes: preparation, characterization, and preservation. Methods Biochem Anal (1988) 1.24

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Photon correlation spectroscopic study of the size distribution of phospholipid vesicles. Biophys J (1982) 1.21

Photosynthetic hydrogen and oxygen production: kinetic studies. Science (1982) 1.20

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Gelation of liposome interior. A novel method for drug encapsulation. FEBS Lett (1992) 1.19

Rifapicin inhibition of trachoma agent in vivo. Nature (1969) 1.18

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Enzymes of complex lipid metabolism. Annu Rev Biochem (1973) 1.14

Isolation of rat brain lecithinase-A, specific for the alpha'-position of lecithin. Biochem Biophys Res Commun (1966) 1.13

Histamine receptor-bearing leukocytes (HRL). I. Detection of histamine receptor-bearing cells by rosette formation with histamine-coated erythrocytes. J Immunol (1974) 1.13

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Lipid organization of the membrane of vesicular stomatitis virus. J Biol Chem (1978) 1.10

Properties of a specific glycolipid transfer protein from bovine brain. Chem Phys Lipids (1985) 1.09

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Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency. Biochim Biophys Acta (1999) 1.09

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Polymers for DNA delivery. Molecules (2005) 1.05

Effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers. Biochemistry (1997) 1.04

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Pyrene phospholipid as a biological fluorescent probe for studying fusion of virus membrane with liposomes. Biochemistry (1988) 1.02

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Polymorphonuclear leukocyte Fc receptors in antibody-dependent cellular cytotoxicity (ADCC). Transplantation (1976) 0.93

Glycolipid transfer protein from bovine brain. Biochemistry (1984) 0.93

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