A Tobler

Author PubWeight™ 75.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53. Cell Death Differ 2001 2.40
2 Clonality and X-inactivation patterns in hematopoietic cell populations detected by the highly informative M27 beta DNA probe. Blood 1994 2.24
3 1 alpha,25-Dihydroxyvitamin D3 inhibits gamma-interferon synthesis by normal human peripheral blood lymphocytes. Proc Natl Acad Sci U S A 1987 1.89
4 Historical demography of Mullerian mimicry in the neotropical Heliconius butterflies. Proc Natl Acad Sci U S A 2004 1.65
5 Fatal cardiac arrhythmia after infusion of dimethyl sulfoxide-cryopreserved hematopoietic stem cells in a patient with severe primary cardiac amyloidosis and end-stage renal failure. Ann Hematol 2000 1.32
6 Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents. Mol Cell Biol 1988 1.27
7 Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells. J Clin Invest 1995 1.25
8 Constitutive mRNA and protein production of macrophage colony-stimulating factor but not of other cytokines by synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients. Br J Rheumatol 1994 1.10
9 Epstein-Barr virus-associated anaplastic large cell lymphoma in renal transplant patients. Am J Clin Pathol 1992 1.10
10 Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formation. Biochem J 1995 1.09
11 Granulocyte-macrophage colony-stimulating factor. Sensitive and receptor-mediated regulation by 1,25-dihydroxyvitamin D3 in normal human peripheral blood lymphocytes. J Clin Invest 1987 1.07
12 Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1. Oncogene 2006 1.06
13 Randomized comparison of interferon alpha and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): prolongation of survival by the combination of interferon alpha and hydroxyurea. Leukemia 2003 1.05
14 Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood. Blood 1995 1.02
15 Hybrid incompatibility is consistent with a hybrid origin of Heliconius heurippa Hewitson from its close relatives, Heliconius cydno Doubleday and Heliconius melpomene Linnaeus. J Evol Biol 2005 1.01
16 Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene 1998 0.99
17 Implementation of the JACIE standards for a haematopoietic progenitor cell transplantation programme: a cost analysis. Bone Marrow Transplant 2004 0.98
18 cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. Nucleic Acids Res 1993 0.98
19 Fibrin glue in surgery: frequent development of inhibitors of bovine thrombin and human factor V. Br J Haematol 1993 0.98
20 [Stenosing ganglioneuromatosis of the small intestine with ileus and ileal rupture]. Schweiz Med Wochenschr 1981 0.95
21 Id2 expression increases with differentiation of human myeloid cells. Blood 1996 0.93
22 DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function. Oncogene 2008 0.93
23 Distinct expression patterns of the p53-homologue p73 in malignant and normal hematopoiesis assessed by a novel real-time reverse transcription-polymerase chain reaction assay and protein analysis. Cancer Res 1999 0.92
24 Enhanced p73 expression during differentiation and complex p73 isoforms in myeloid leukemia. Biochem Biophys Res Commun 2000 0.92
25 The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1. Leukemia 2010 0.91
26 Clonal analysis of human tumors with M27 beta, a highly informative polymorphic X chromosomal probe. J Clin Invest 1992 0.90
27 Randomized study of recombinant human granulocyte colony-stimulating factor after high-dose chemotherapy and autologous bone marrow transplantation for high-risk lymphoid malignancies. J Clin Oncol 1994 0.89
28 Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia. Ann Oncol 2001 0.89
29 Factors associated with transfusion requirements during treatment for acute myelogenous leukemia. Ann Hematol 1993 0.88
30 Marrow fibrosis, indicator of therapy failure in chronic myeloid leukemia - prospective long-term results from a randomized-controlled trial. Leukemia 2003 0.88
31 Human small cell lung cancer expresses the octamer DNA-binding and nervous system-specific transcription factor N-Oct 3 (brain-2). Cancer Res 1992 0.87
32 Expression of Id2 and Id3 mRNA in human lymphocytes. Leuk Res 1995 0.87
33 A novel BCR-ABL transcript e2a2 in a chronic myelogenous leukaemia patient with a duplicated Ph-chromosome and monosomy 7. Br J Haematol 1999 0.87
34 Randomized trial of daily versus weekly administration of 2-chlorodeoxyadenosine in patients with hairy cell leukemia: a multicenter phase III trial (SAKK 32/98). Leuk Lymphoma 2009 0.86
35 The differentiation pathway of HL60 cells is a model system for studying the specific regulation of some myeloid genes. Cell Growth Differ 1992 0.86
36 Clonal X-inactivation analysis of human tumours using the human androgen receptor gene (HUMARA) polymorphism: a non-radioactive and semiquantitative strategy applicable to fresh and archival tissue. Mol Cell Probes 1997 0.86
37 Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers. Cancer Res 1995 0.85
38 Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells. Leukemia 1997 0.85
39 Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a phase II study. Ann Oncol 2002 0.85
40 Expression of TCL1 in hematologic disorders. Pathobiology 2001 0.84
41 Lymphocyte cell lines from vitamin D-dependent rickets type II show functional defects in the 1 alpha,25-dihydroxyvitamin D3 receptor. Mol Cell Endocrinol 1990 0.84
42 Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias. Blood 1996 0.84
43 Differential expression of p73 splice variants and protein in benign and malignant ovarian tumours. Int J Cancer 2000 0.83
44 Studying clonal heterogeneity in human cancers. Cancer Res 1993 0.83
45 Different p16INK4a and p14ARF expression patterns in acute myeloid leukaemia and normal blood leukocytes. Leuk Lymphoma 2001 0.83
46 Bone marrow trephine biopsies as a source of nucleic acids for molecular diagnosis of haematological neoplasms. Br J Haematol 1990 0.83
47 Tumour heterogeneity and clonality--an old theme revisited. Ann Oncol 1996 0.82
48 Cytosine demethylation of the proteinase-3/myeloblastin primary granule protease gene during phagocyte development. Leukemia 1999 0.82
49 Recombinant human tumor necrosis factor alpha regulates c-myc expression in HL-60 cells at the level of transcription. Blood 1987 0.82
50 The polymerase chain reaction: a new tool for the detection of minimal residual disease in haematological malignancies. Eur J Cancer 1991 0.82
51 Morphological and functional polymorphism within clonal thyroid nodules. J Clin Endocrinol Metab 1993 0.82
52 Polyclonal and monoclonal thyroid nodules coexist within human multinodular goiters. J Clin Endocrinol Metab 1994 0.82
53 Post-remission therapy of adult acute myeloid leukaemia: one cycle of high-dose versus standard-dose cytarabine. Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK). Ann Oncol 1997 0.82
54 The two faces of p73. Cell Death Differ 2002 0.82
55 Undifferentiated thyroid tumors of diffuse small cell type. Histological and immunohistochemical evidence for their lymphomatous nature. Virchows Arch A Pathol Anat Histopathol 1984 0.81
56 The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X chromosomes. Mamm Genome 1994 0.81
57 Clonal loss of heterozygosity in microdissected Hodgkin and Reed-Sternberg cells. J Natl Cancer Inst 1999 0.81
58 The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells. Br J Haematol 1999 0.81
59 Retinoids. Structure-function relationship in normal and leukemic hematopoiesis in vitro. J Clin Invest 1986 0.80
60 Interferon-alpha before allogeneic bone marrow transplantation in chronic myelogenous leukemia does not affect outcome adversely, provided it is discontinued at least 90 days before the procedure. Blood 1999 0.79
61 Interleukin-8 expression by fetal and neonatal pulmonary cells in hyaline membrane disease and amniotic infection. Pediatr Res 2000 0.79
62 IgG2 and IgG4 subclass deficiency and Evan's syndrome in an adult patient. J Allergy Clin Immunol 1992 0.79
63 Hematologic, clinical, and cytogenetic analysis in 109 patients with primary myelodysplastic syndrome. Prognostic significance of morphology and chromosome findings. Cancer Genet Cytogenet 1994 0.79
64 Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia. Oncogene 1999 0.78
65 The induction kinetics of Il-8 messenger RNA in HL60 cells demonstrate the participation of negative-acting gene(s). Leuk Res 1995 0.78
66 The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias. Leukemia 2007 0.78
67 Myeloblastin/proteinase 3 belongs to the set of negatively regulated primary response genes expressed during in vitro myeloid differentiation. Biochem Biophys Res Commun 1994 0.78
68 An interleukin-8 (IL-8) cDNA clone identifies a frequent HindIII polymorphism. Hum Genet 1993 0.78
69 Up-regulation of p21WAF1 expression in myeloid cells is activated by the protein kinase C pathway. Br J Cancer 1997 0.77
70 Comparative detection and quantitation of human CDK inhibitor mRNA expression of p15INK4B, p16INK4A, p16beta, p18INK4C, p19INK4D, p21WAF1, p27KIP1 and p57KIP2 by RT-PCR using a polycompetitive internal standard. Br J Haematol 1997 0.77
71 Acute lymphoblastic leukaemia in childhood: cell proliferation without rest. Br J Haematol 1997 0.77
72 Randomized study of the combination of hydroxyurea and interferon alpha versus hydroxyurea monotherapy during the chronic phase of chronic myelogenous leukemia (CML Study II). The German CML Study Group. Bone Marrow Transplant 1996 0.77
73 In childhood acute lymphoblastic leukemia the hypophosphorylated retinoblastoma protein, p110RB, is diminished, as compared with normal CD34+ peripheral blood progenitor cells. Pediatr Res 1999 0.77
74 Immunogenotyping with antigen receptor gene probes as a diagnostic tool in childhood acute lymphoblastic leukaemia. Eur J Haematol 1990 0.77
75 Assessment of DNA 'fingerprinting' as a method for validating the identity of cancer cell lines maintained in long-term culture. Nucleic Acids Res 1991 0.77
76 Cytostatic drug resistance: parallel assessment of glutathione-based detoxifying enzymes, O6-alkylguanine-DNA-alkyltransferase and P-glycoprotein in adult patients with leukaemia. Br J Haematol 1993 0.76
77 Structural integrity of the cyclin-dependent kinase inhibitor genes, p15, p16 and p18 in myeloid leukaemias. Br J Haematol 1995 0.76
78 Severe inclusion body beta-thalassaemia with haemolysis in a patient double heterozygous for beta(0)-thalassaemia and quadruplicated alpha-globin gene arrangement of the anti-4.2 type. Br J Haematol 1999 0.76
79 Detection of microsatellite markers in leukaemia using DNA from archival bone marrow smears. Br J Haematol 1996 0.76
80 Interleukin-12 expression in human lymphomas and nonneoplastic lymphoid disorders. Blood 1995 0.75
81 Lyn, a src-like tyrosine-specific protein kinase, is expressed in HL60 cells induced to monocyte-like or granulocyte-like cells. Biochem Biophys Res Commun 1992 0.75
82 A myeloblastin/proteinase-3 cDNA clone identifies a BglII and a PvuII restriction fragment length polymorphism. Hum Genet 1993 0.75
83 Autotransplants with peripheral blood stem cells and clinical results obtained in children: a review. Eur J Pediatr 1993 0.75
84 Clonal analysis of a B-cell lymphoma with recurrent spontaneous remissions and evolution into chronic lymphocytic leukaemia. Ann Oncol 1996 0.75
85 Divergent expression of cyclin-dependent kinase inhibitors (CKI) and p14ARF/p16 beta in non-Hodgkin's lymphomas and chronic lymphocytic leukemia. Leuk Lymphoma 2000 0.75
86 Acquired von Willebrand syndrome in a myeloproliferative disorder. Case 6. Hamostaseologie 2003 0.75
87 Venous thrombosis after caesarean section in a young woman with homozygous APC resistance and type I protein S deficiency. Eur J Haematol 1997 0.75
88 Cancer diagnosis by molecular genetic probes: the present and the promise. Ann Oncol 1991 0.75
89 [Mobilization and transplantation of autologous hematopoietic stem and progenitor cells from peripheral blood: principles and applications]. Schweiz Med Wochenschr 1996 0.75
90 Severe neutropenia in T-large granular lymphocyte leukemia corrected by intensive immunosuppression. Ann Hematol 1996 0.75
91 The number of circulating CD34+ blood cells predicts the colony-forming capacity of leukapheresis products in children. Bone Marrow Transplant 1995 0.75
92 [Stem cell apheresis--experiences in children]. Beitr Infusionsther Transfusionsmed 1994 0.75
93 The influence of tumour necrosis factor-alpha on phagocytosis of human erythrocytes by autologous monocytes/macrophages. Eur J Haematol 1997 0.75
94 Increased bone metabolism in a patient undergoing long-term rhG-CSF treatment for idiopathic acquired neutropenia. Ann Hematol 1993 0.75
95 [Large cell anaplastic lymphomas in the immunocompromised host]. Verh Dtsch Ges Pathol 1991 0.75
96 [HemoSurf--an interactive hematology atlas on the world wide web]. Schweiz Med Wochenschr 1998 0.75
97 [2-CDA in treatment of hairy cell leukemia: a comparison between intravenous and subcutaneous administration. Swiss Study Group of Applied Cancer Research]. Schweiz Med Wochenschr 1998 0.75
98 High incidence of infections after 2-chlorodeoxyadenosine (2-CDA) therapy in patients with malignant lymphomas and chronic and acute leukaemias. Ann Oncol 1994 0.75
99 [Prognostic value of bone marrow examinations on day 8 and day 17 of the first induction therapy cycle in acute myeloid leukemia]. Schweiz Med Wochenschr 1994 0.75
100 Myeloperoxidase is a primary response gene in HL60 cells, directly regulated during hematopoietic differentiation. Biochem Biophys Res Commun 1991 0.75
101 Inhibition of the arachidonic acid pathway prevents induction of IL-8 mRNA by phorbol ester and changes the release of IL-8 from HL 60 cells: differential inhibition of induced expression of IL-8, TNF-alpha, IL-1 alpha, and IL-1 beta. J Cell Physiol 1995 0.75
102 Single institution experience with mobilization, harvesting, and reinfusion of peripheral blood stem cells in children with a solid tumor or leukemia. Pediatr Hematol Oncol 1994 0.75
103 Real-time process/quality control for HPC processing. Cytotherapy 2004 0.75
104 Evaluation of the Fresenius cell separator AS 104 for harvesting peripheral blood stem cells in pediatric patients. Transfus Sci 1994 0.75
105 Treatment intensity significantly influencing fibrosis in bone marrow independently of the cytogenetic response: meta-analysis of the long-term results from two prospective controlled trials on chronic myeloid leukemia. Leukemia 2004 0.75
106 Purity and recovery of the CD34+ cell fraction, obtained by the CEPRATE selection system from PBSC collections, can be augmented by meticulous washing steps. Cytotherapy 1999 0.75
107 Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase. Biochem Biophys Res Commun 1999 0.75
108 Peripheral blood progenitor cell collections in children with low platelet counts are safe. Bone Marrow Transplant 1997 0.75
109 Intensive induction and consolidation chemotherapy in a young woman with acute myeloid leukemia and severe chronic renal failure. Ann Hematol 1996 0.75
110 Randomized studies with interferon in chronic myelogenous leukemia (CML) and comparative molecular aspects. German CML Study Group. Leukemia 1997 0.75
111 [Differential anemia diagnosis]. Praxis (Bern 1994) 1997 0.75
112 Prediction of 18-month survival in patients with primary myelodysplastic syndrome. A regression model and scoring system based on the combination of chromosome findings and the Bournemouth score. Cancer Genet Cytogenet 1995 0.75
113 Cold agglutinin syndrome and liver transplantation. Vox Sang 1994 0.75
114 Cytogenetic response to prior treatment with interferon-alpha is predictive for survival after allogeneic hematopoietic stem cell transplantation in chronic myeloid leukemia. Leukemia 2006 0.75
115 [Treatment of severe idiopathic cold-agglutinin diseases using interferon-alpha 2b]. Schweiz Med Wochenschr 1994 0.75
116 Relapse of acute myeloblastic leukaemia presenting as temporal bone chloroma with facial nerve paralysis. Ann Oncol 1993 0.75
117 Sampling bias and logistical problems of molecular analyses in a clinical leukaemia trial. Swiss Group for Clinical Cancer Research (SAKK) Br J Haematol 1998 0.75
118 [Myelodysplastic syndromes--an overview for the practitioner]. Ther Umsch 2004 0.75
119 Reduced dose of subcutaneous cladribine induces identical response rates but decreased toxicity in pretreated chronic lymphocytic leukaemia. Swiss Group for Clinical Cancer Research (SAKK). Ann Oncol 1998 0.75