Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment.

PubWeight™: 1.98‹?› | Rank: Top 2%

🔗 View Article (PMID 11698303)

Published in Blood on November 15, 2001

Authors

A Janowska-Wieczorek1, M Majka, J Kijowski, M Baj-Krzyworzeka, R Reca, A R Turner, J Ratajczak, S G Emerson, M A Kowalska, M Z Ratajczak

Author Affiliations

1: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

Articles citing this

Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol (2009) 5.01

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion. J Mol Histol (2004) 4.08

Regulation of CXCR4 signaling. Biochim Biophys Acta (2006) 3.16

Microvesicles and viral infection. J Virol (2011) 2.10

Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp Hematol (2010) 2.01

Exosome/microvesicle-mediated epigenetic reprogramming of cells. Am J Cancer Res (2010) 1.96

Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation. Stem Cells (2007) 1.92

Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles. Blood (2008) 1.83

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood (2012) 1.80

Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol (2010) 1.43

The evolution of the cancer niche during multistage carcinogenesis. Nat Rev Cancer (2013) 1.36

The paradoxical dynamism of marrow stem cells: considerations of stem cells, niches, and microvesicles. Stem Cell Rev (2008) 1.34

The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue. Vascul Pharmacol (2009) 1.27

Strategies to enhance umbilical cord blood stem cell engraftment in adult patients. Expert Rev Hematol (2010) 1.25

Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumor microRNAs. Stem Cells (2012) 1.23

Stem cell plasticity revisited: the continuum marrow model and phenotypic changes mediated by microvesicles. Exp Hematol (2010) 1.22

Cellular phenotype switching and microvesicles. Adv Drug Deliv Rev (2010) 1.21

Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles. Stem Cells Dev (2012) 1.19

Extracellular vesicles and their convergence with viral pathways. Adv Virol (2012) 1.18

Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles--a role of the endocytic-exocytic pathway. EMBO Mol Med (2011) 1.12

Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thromb Haemost (2008) 1.12

The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation. Leukemia (2011) 1.10

Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming. Stem Cell Res Ther (2015) 1.09

Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors. Circulation (2015) 1.02

The ins and outs of hematopoietic stem cells: studies to improve transplantation outcomes. Stem Cell Rev (2011) 1.01

Microvesicle induction of prostate specific gene expression in normal human bone marrow cells. J Urol (2010) 0.99

Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment. J Mol Med (Berl) (2017) 0.97

Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Cardiovascular and Cerebrovascular Diseases. Biomed Res Int (2015) 0.97

Targeting stem cell niches and trafficking for cardiovascular therapy. Pharmacol Ther (2010) 0.95

Marrow cell genetic phenotype change induced by human lung cancer cells. Exp Hematol (2011) 0.94

Innate immunity derived factors as external modulators of the CXCL12-CXCR4 axis and their role in stem cell homing and mobilization. Theranostics (2013) 0.93

Horizontal transfer of RNA and proteins between cells by extracellular microvesicles: 14 years later. Clin Transl Med (2016) 0.92

Stability of membranous nanostructures: a possible key mechanism in cancer progression. Int J Nanomedicine (2012) 0.92

The Gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiation. Int J Radiat Oncol Biol Phys (2013) 0.92

Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP. Biochem Res Int (2012) 0.89

Human liver stem cells and derived extracellular vesicles improve recovery in a murine model of acute kidney injury. Stem Cell Res Ther (2014) 0.89

Isolation and characterization of microparticles in sputum from cystic fibrosis patients. Respir Res (2010) 0.89

Monocytic microparticles promote atherogenesis by modulating inflammatory cells in mice. J Cell Mol Med (2012) 0.88

Intravital imaging of mesenchymal stem cell trafficking and association with platelets and neutrophils. Stem Cells (2015) 0.87

Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy. PLoS One (2012) 0.86

Small but mighty: microparticles as mediators of tumor progression. Cancer Microenviron (2014) 0.86

Microvesicles derived from human Wharton's jelly mesenchymal stem cells promote human renal cancer cell growth and aggressiveness through induction of hepatocyte growth factor. PLoS One (2014) 0.85

The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR Res (2008) 0.85

Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells. J Cell Mol Med (2012) 0.85

Platelet-derived microparticles and the potential of glycoprotein IIb/IIIa antagonists in treating acute coronary syndrome. Tex Heart Inst J (2009) 0.84

Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake. Sci Rep (2015) 0.83

Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells. Stem Cell Rev (2016) 0.82

Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells. PLoS One (2015) 0.82

The Role of Microvesicles Derived from Mesenchymal Stem Cells in Lung Diseases. Biomed Res Int (2015) 0.82

Cationic liposome-mediated CXCR4 gene delivery into hematopoietic stem/progenitor cells: implications for clinical transplantation and gene therapy. Stem Cells Dev (2011) 0.81

Regulation of prostate cancer progression by the tumor microenvironment. Cancer Lett (2016) 0.81

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity (2015) 0.80

MicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and Treatment. J Clin Med (2015) 0.79

Understanding the biosynthesis of platelets-derived extracellular vesicles. Immun Inflamm Dis (2015) 0.78

Microvesicles as immune orchestra conductors. Blood (2008) 0.78

Tumor exosomes: a novel biomarker? J Gastrointest Oncol (2011) 0.77

Direct Reprogramming of Human Amniotic Fluid Stem Cells by OCT4 and Application in Repairing of Cerebral Ischemia Damage. Int J Biol Sci (2016) 0.77

Quo Vadis medycyno regeneracyjna?: Quo Vadis Regenerative Medicine? Acta Haematol Pol (2013) 0.76

Transmission of Information in Neoplasia by Extracellular Vesicles. Biomed Res Int (2015) 0.76

Re-Engineering Extracellular Vesicles as Smart Nanoscale Therapeutics. ACS Nano (2017) 0.76

Extracellular Vesicle-Mediated Reversal of Paclitaxel Resistance in Prostate Cancer. Crit Rev Oncog (2015) 0.75

MicroRNAs in heart failure: Non-coding regulators of metabolic function. Biochim Biophys Acta (2016) 0.75

The Analysis of the Relationship between Multiple Myeloma Cells and Their Microenvironment. J Cancer (2015) 0.75

Nuclear transport of cancer extracellular vesicle-derived biomaterials through nuclear envelope invagination-associated late endosomes. Oncotarget (2017) 0.75

Extracellular vesicles in renal disease. Nat Rev Nephrol (2017) 0.75

Articles by these authors

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet (1999) 6.61

Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia (2006) 6.45

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia (2006) 6.31

Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science (1999) 6.02

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proc Natl Acad Sci U S A (1989) 5.07

A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia (2006) 4.39

The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis. Leukemia (2006) 3.08

Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood (2001) 2.34

Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia (2006) 2.17

Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor. J Exp Med (1994) 2.14

Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia (2004) 2.08

Nucleic acid therapeutics: state of the art and future prospects. Blood (1998) 1.96

Human recombinant granulocyte-macrophage colony-stimulating factor: a multilineage hematopoietin. Science (1985) 1.86

Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex. Leukemia (2010) 1.86

Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells. Leukemia (2009) 1.80

A hypothesis for an embryonic origin of pluripotent Oct-4(+) stem cells in adult bone marrow and other tissues. Leukemia (2007) 1.77

Circulating progenitor cells in stable coronary heart disease and acute coronary syndromes: relevant reparatory mechanism? Heart (2007) 1.75

Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood (1995) 1.69

Selective turnover and shedding of H-2K and H-2D antigens is controlled by the major histocompatibility complex. Implications for H-2-restricted recognition. J Exp Med (1980) 1.68

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc Natl Acad Sci U S A (1994) 1.67

Human osteoblasts support human hematopoietic progenitor cells in vitro bone marrow cultures. Blood (1996) 1.65

Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies? Leukemia (2011) 1.64

The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem Cells (2001) 1.59

Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J Immunol (1998) 1.57

I-Kk and H-2Kk antigens are shed as supramolecular particles in association with membrane lipids. J Immunol (1981) 1.54

Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells. Leukemia (2005) 1.51

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes. Leukemia (2009) 1.50

Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer. Oncogene (2011) 1.50

Innate immunity as orchestrator of stem cell mobilization. Leukemia (2010) 1.46

Leu-1+ (CD5+) B cells. A major lymphoid subpopulation in human fetal spleen: phenotypic and functional studies. J Immunol (1986) 1.46

Expansion in bioreactors of human progenitor populations from cord blood and mobilized peripheral blood. Blood Cells (1994) 1.46

Sensitive detection of rare circulating neuroblastoma cells by the reverse transcriptase-polymerase chain reaction. Cancer Res (1992) 1.46

The management and clinical course of testicular seminoma: 15 years' experience at a single institution. Clin Oncol (R Coll Radiol) (1998) 1.43

Molecular signature of adult bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin. Leukemia (2010) 1.43

Splenectomy during partial remission in thrombotic thrombocytopenic purpura with prolonged plasma exchange dependency. Am J Hematol (1999) 1.41

CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages. Exp Hematol (1992) 1.37

Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. J Clin Invest (1985) 1.36

SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood (1999) 1.36

A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients. Leukemia (2011) 1.35

Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites. J Exp Med (1993) 1.31

Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs. Proc Natl Acad Sci U S A (2000) 1.29

Identification of very small embryonic like (VSEL) stem cells in bone marrow. Cell Tissue Res (2007) 1.27

Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke. Leukemia (2006) 1.25

Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines. Exp Hematol (2000) 1.24

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors. Leukemia (2011) 1.24

Turnover and shedding of Ia antigens by murine spleen cells in culture. J Immunol (1979) 1.23

Growth factors and cytokines upregulate gelatinase expression in bone marrow CD34(+) cells and their transmigration through reconstituted basement membrane. Blood (1999) 1.23

Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. Blood (2000) 1.22

Higher number of stem cells in the bone marrow of circulating low Igf-1 level Laron dwarf mice--novel view on Igf-1, stem cells and aging. Leukemia (2011) 1.20

Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood (1993) 1.18

Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells. Leukemia (2004) 1.17

Surgery in Kurdistan. Ann R Coll Surg Engl (1977) 1.14

Physical and chemical characteristics and acceptability of home style beef jerky. Meat Sci (2007) 1.11

Role of p53 in hematopoietic recovery after cytotoxic treatment. Blood (1998) 1.11

The role of insulin (INS) and insulin-like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum-free conditions--comparison to other cytokines and growth factors. Leukemia (1998) 1.11

Stimulation of [3H]thymidine uptake in mouse marrow by granulocyte-macrophage colony stimulating factor from mouse lung conditioned medium. J Immunol Methods (1983) 1.10

The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation. Leukemia (2011) 1.10

Regulation of interleukin 3 gene induction in normal human T cells. J Clin Invest (1989) 1.10

The role of osteoblasts in the hematopoietic microenvironment. Stem Cells (1998) 1.09

Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells. Leukemia (2011) 1.07

Bone marrow stromal fibroblasts secrete interleukin-6 and granulocyte-macrophage colony-stimulating factor in the absence of inflammatory stimulation: demonstration by serum-free bioassay, enzyme-linked immunosorbent assay, and reverse transcriptase polymerase chain reaction. Blood (1992) 1.07

Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. J Clin Invest (1999) 1.06

Bone marrow-derived very small embryonic-like stem cells: their developmental origin and biological significance. Dev Dyn (2007) 1.06

Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes. Leukemia (2009) 1.06

Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by upstream stimulating factor (USF)-1 and USF-2. J Exp Med (2000) 1.05

Matrix metalloproteinase and tissue inhibitors of metalloproteinase secretion by haematopoietic and stromal precursors and their production in normal and leukaemic long-term marrow cultures. Br J Haematol (2001) 1.05

Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus. Blood (2001) 1.05

Defective engraftment of C3aR-/- hematopoietic stem progenitor cells shows a novel role of the C3a-C3aR axis in bone marrow homing. Leukemia (2009) 1.05