1
|
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
|
Cell
|
1997
|
15.96
|
2
|
Effects of the obese gene product on body weight regulation in ob/ob mice.
|
Science
|
1995
|
13.57
|
3
|
Prospective randomized controlled trial of extended-release oxybutynin chloride and tolterodine tartrate in the treatment of overactive bladder: results of the OBJECT Study.
|
Mayo Clin Proc
|
2001
|
3.17
|
4
|
DNA sequence of the araBAD promoter in Escherichia coli B/r.
|
Proc Natl Acad Sci U S A
|
1978
|
2.51
|
5
|
APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity.
|
Nat Immunol
|
2000
|
2.19
|
6
|
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway.
|
Nat Med
|
2000
|
2.18
|
7
|
TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation.
|
J Exp Med
|
2000
|
2.10
|
8
|
A rapid high-yield purification procedure for the cyclic adenosine 3',5'-monophosphate receptor protein from Escherichia coli.
|
Biochim Biophys Acta
|
1978
|
1.93
|
9
|
Three-dimensional structure of interleukin-2.
|
Science
|
1987
|
1.63
|
10
|
Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor.
|
Science
|
1991
|
1.62
|
11
|
Effects of assistive devices on cardiorespiratory demands in older adults.
|
Phys Ther
|
1996
|
1.52
|
12
|
Effect of endotoxin on serum granulocyte and granulocyte-macrophage colony-stimulating factor levels in dogs.
|
J Infect Dis
|
1992
|
1.49
|
13
|
Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor.
|
Proteins
|
1996
|
1.47
|
14
|
A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.
|
J Bone Miner Res
|
1999
|
1.47
|
15
|
Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family.
|
Proc Natl Acad Sci U S A
|
1999
|
1.34
|
16
|
Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.
|
Clin Immunol
|
2007
|
1.33
|
17
|
Flt3 ligand structure and unexpected commonalities of helical bundles and cystine knots.
|
Nat Struct Biol
|
2000
|
1.30
|
18
|
The effect of carbohydrate on the structure and stability of erythropoietin.
|
J Biol Chem
|
1991
|
1.18
|
19
|
Role of glycosylation on the secretion and biological activity of erythropoietin.
|
Biochemistry
|
1992
|
1.16
|
20
|
Protection against the mortality associated with disease models mediated by TNF and IFN-gamma in mice lacking IFN regulatory factor-1.
|
J Immunol
|
1999
|
1.13
|
21
|
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS.
|
Int Immunol
|
2000
|
1.13
|
22
|
IL-18-binding protein protects against lipopolysaccharide- induced lethality and prevents the development of Fas/Fas ligand-mediated models of liver disease in mice.
|
J Immunol
|
2001
|
1.12
|
23
|
Hybrid plasmids containing the araBAD genes of Escherichia coli B/r.
|
Gene
|
1978
|
1.12
|
24
|
Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates.
|
Blood
|
1995
|
1.01
|
25
|
Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes.
|
J Biol Chem
|
1997
|
1.01
|
26
|
GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family.
|
J Biol Chem
|
1997
|
0.98
|
27
|
Comparison of the biophysical characteristics of human brain-derived neurotrophic factor, neurotrophin-3, and nerve growth factor.
|
J Biol Chem
|
1993
|
0.98
|
28
|
Asn to Lys mutations at three sites which are N-glycosylated in the mammalian protein decrease the aggregation of Escherichia coli-derived erythropoietin.
|
Protein Eng
|
2001
|
0.92
|
29
|
Action of interleukin-3, G-CSF, and GM-CSF on highly enriched human hematopoietic progenitor cells: synergistic interaction of GM-CSF plus G-CSF.
|
Blood
|
1989
|
0.91
|
30
|
Interaction of granulocyte colony-stimulating factor (G-CSF) with its receptor. Evidence that Glu19 of G-CSF interacts with Arg288 of the receptor.
|
J Biol Chem
|
1999
|
0.91
|
31
|
Effect of povidone-iodine and saline soaking on bacterial counts in acute, traumatic, contaminated wounds.
|
Ann Emerg Med
|
1990
|
0.89
|
32
|
Cardiovascular and thermal responses of triathlon performance.
|
Med Sci Sports Exerc
|
1988
|
0.89
|
33
|
Selective stimulation of human thymocyte subpopulations by recombinant IL-4 and IL-3.
|
Cell Immunol
|
1989
|
0.85
|
34
|
Pegylated megakaryocyte growth and development factor abrogates the lethal thrombocytopenia associated with carboplatin and irradiation in mice.
|
Blood
|
1995
|
0.84
|
35
|
Hematologic and bone marrow changes after short- and long-term administration of two recombinant bovine granulocyte colony-stimulating factors.
|
Vet Pathol
|
1992
|
0.84
|
36
|
Effect of blood donation on maximal oxygen consumption.
|
J Sports Med Phys Fitness
|
2006
|
0.84
|
37
|
Structure of unfolded and refolded recombinant derived [Ala125]interleukin 2.
|
Biochemistry
|
1986
|
0.83
|
38
|
Interleukin-4 induces expression of the CD45RA antigen on human thymocyte subpopulations.
|
Int Immunol
|
1990
|
0.83
|
39
|
Crystals and a low resolution structure of interleukin-2.
|
J Biol Chem
|
1987
|
0.83
|
40
|
Low-resolution structure of recombinant human granulocyte-macrophage colony stimulating factor.
|
J Mol Biol
|
1991
|
0.79
|
41
|
Inhibition of granulocyte-macrophage colony-stimulating factor (GM-CSF) activity by suramin and suramin analogues is correlated to interaction with the GM-CSF nucleotide-binding site.
|
Cancer Res
|
1995
|
0.79
|
42
|
Effect of recombinant canine granulocyte-macrophage colony-stimulating factor on hematopoietic recovery after otherwise lethal total body irradiation.
|
Blood
|
1994
|
0.79
|
43
|
Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice.
|
J Immunol
|
1985
|
0.78
|
44
|
Thrombocytopenia in dogs induced by granulocyte-macrophage colony-stimulating factor: increased destruction of circulating platelets.
|
Blood
|
1995
|
0.78
|
45
|
Phase I trial of intravenous and intraperitoneal administration of granulocyte-macrophage colony-stimulating factor.
|
J Immunother Emphasis Tumor Immunol
|
1994
|
0.78
|
46
|
Crystallization and preliminary X-ray analysis of leukemia inhibitory factor.
|
FEBS Lett
|
1993
|
0.77
|
47
|
Rescue of anti-influenza A virus cytotoxic T-lymphocyte responses in chemotherapy-suppressed mice.
|
J Virol
|
1984
|
0.77
|
48
|
Sites of iodination in recombinant human brain-derived neurotrophic factor and its effect on neurotrophic activity.
|
Protein Sci
|
1993
|
0.77
|
49
|
Sexual issues and research in counseling the postmyocardial infarction patient.
|
J Cardiovasc Nurs
|
1990
|
0.75
|
50
|
Cloning and expression of the gene encoding a novel proteinase from Tritirachium album limber.
|
Adv Exp Med Biol
|
1996
|
0.75
|
51
|
Exercise prescription for cardiac patients. Reasons for concern.
|
Sports Med
|
1986
|
0.75
|
52
|
Molecular cloning and in vivo evaluation of canine granulocyte-macrophage colony-stimulating factor.
|
Blood
|
1991
|
0.75
|
53
|
Lysis of spontaneous murine breast tumors by human interleukin 2-stimulated syngeneic T-lymphocytes.
|
Cancer Res
|
1985
|
0.75
|
54
|
Identification of N-terminus peptide of human granulocyte/macrophage colony stimulating factor as the site of nucleotide interaction.
|
Biochem Biophys Res Commun
|
1995
|
0.75
|
55
|
Parameters for the evaluation of IL-2 stability.
|
Lymphokine Res
|
1986
|
0.75
|
56
|
Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis.
|
J Biol Response Mod
|
1985
|
0.75
|
57
|
Influence of a 36-h fast on the central and peripheral components of VO2 during submaximal exercise and peak oxygen uptake.
|
J Sports Sci
|
1995
|
0.75
|
58
|
The influence of lower extremity muscular endurance training on cardiac output and related measures.
|
J Sports Med Phys Fitness
|
1982
|
0.75
|
59
|
Detection and quantification of cocaine metabolites in urine samples from horses administered cocaine.
|
J Vet Pharmacol Ther
|
2003
|
0.75
|
60
|
Reproducibility of tethered swimming in exercise rehabilitation research.
|
Am Correct Ther J
|
1983
|
0.75
|
61
|
Effects of qigong on cardiorespiratory changes: a preliminary study.
|
Am J Chin Med
|
1993
|
0.75
|
62
|
Carotid palpation and heart rate changes in postmyocardial infarction patients.
|
Arch Phys Med Rehabil
|
1983
|
0.75
|
63
|
Cardiorespiratory and hemodynamic responses to inversion and inversion with sit-ups.
|
J Sports Med Phys Fitness
|
1989
|
0.75
|
64
|
[Role of the community pharmacist in the management of drug related problems in home care patients].
|
J Pharm Belg
|
2012
|
0.75
|
65
|
Preparative electrofocusing for industrial applications.
|
Prep Biochem Biotechnol
|
1997
|
0.75
|
66
|
Perforation of the cecum, as a complication of pleural biopsy.
|
Acta Gastroenterol Latinoam
|
1979
|
0.75
|
67
|
Identification and characterization of a nucleotide binding site on recombinant murine granulocyte/macrophage-colony stimulating factor.
|
Bioconjug Chem
|
1993
|
0.75
|
68
|
A cinematographical analysis of the peach basket from handstand to handstand on the parallel bars.
|
J Sports Med Phys Fitness
|
1977
|
0.75
|
69
|
Evaluation of recombinant canine granulocyte colony-stimulating factor as an inducer of granulopoiesis. A pilot study.
|
J Vet Intern Med
|
1991
|
0.75
|
70
|
Identification of interleukin 6 as a synergistic factor for the differentiation-inducing effect of TNF on leukemic ML-1 cells.
|
Leuk Res
|
1990
|
0.75
|
71
|
Carotid palpation at two exercise intensities.
|
Med Sci Sports Exerc
|
1985
|
0.75
|