R E Kuc

Author PubWeight™ 27.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol 2000 1.78
2 Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium. Circ Res 1993 1.56
3 Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: majority of the ETA sub-type. Br J Pharmacol 1995 1.48
4 Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ETA and ETB in human kidney. Kidney Int 1993 1.22
5 Characterization of two new ETB selective radioligands, [125I]-BQ3020 and [125I]-[Ala1,3,11,15]ET-1 in human heart. Br J Pharmacol 1992 1.17
6 Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol 2007 1.11
7 Human endothelin receptors characterized using reverse transcriptase-polymerase chain reaction, in situ hybridization, and subtype-selective ligands BQ123 and BQ3020: evidence for expression of ETB receptors in human vascular smooth muscle. J Cardiovasc Pharmacol 1993 1.01
8 Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro. Br J Pharmacol 1994 1.01
9 Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1. Am J Physiol Regul Integr Comp Physiol 2001 1.00
10 Differential distribution of endothelin peptides and receptors in human adrenal gland. Histochem J 1996 0.96
11 [125I]-PD151242: a selective ligand for endothelin ETA receptors in human kidney which localizes to renal vasculature. Br J Pharmacol 1994 0.93
12 Cellular expression of isoforms of endothelin-converting enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and endothelin-converting enzyme-2. J Cardiovasc Pharmacol 2000 0.90
13 Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol 2010 0.88
14 Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated. J Cardiovasc Pharmacol 1993 0.87
15 Affinity and selectivity of PD156707, a novel nonpeptide endothelin antagonist, for human ET(A) and ET(B) receptors. J Pharmacol Exp Ther 1997 0.86
16 Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin-1, to distinguish between these agonists in binding experiments. Br J Pharmacol 1996 0.86
17 Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro. Br J Pharmacol 2001 0.86
18 Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system. Can J Physiol Pharmacol 2002 0.85
19 Expression of endothelin peptides and mRNA in the human heart. Clin Sci (Lond) 1996 0.85
20 ETA receptors predominate in the human vasculature and mediate constriction. J Cardiovasc Pharmacol 1995 0.85
21 Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707. Neurosurgery 1998 0.83
22 Characterization of endothelin receptors in human brain cortex, gliomas, and meningiomas. J Cardiovasc Pharmacol 1995 0.83
23 Maternal dexamethasone increases endothelin-1 sensitivity and endothelin a receptor expression in ovine foetal placental arteries. Placenta 2003 0.81
24 Characterization of [125I]-PD164333, an ETA selective non-peptide radiolabelled antagonist, in normal and diseased human tissues. Br J Pharmacol 1998 0.81
25 Characterization of the snake venom ligand [125I]-DNP binding to natriuretic peptide receptor-A in human artery and potent DNP mediated vasodilatation. Br J Pharmacol 2006 0.80
26 Endothelin-converting enzyme in the human vasculature: evidence for differential conversion of big endothelin-3 by endothelial and smooth-muscle cells. J Cardiovasc Pharmacol 1998 0.80
27 [125I]-PD151242: a selective radioligand for human ETA receptors. Br J Pharmacol 1994 0.78
28 Characterization of site-directed antisera against endothelin-converting enzymes. J Cardiovasc Pharmacol 1998 0.75
29 Analysis of endogenous human endothelin peptides by high-performance liquid chromatography and mass spectrometry. J Cardiovasc Pharmacol 1995 0.75
30 Potency of PD155080, an orally active ETA receptor antagonist, determined for human endothelin receptors. J Cardiovasc Pharmacol 1995 0.75
31 Isolation of human cardiac endothelin receptors by a peptide-receptor mobility shift assay. Clin Sci (Lond) 1993 0.75
32 Tissue-specific modulation of endothelin receptors in a rat model of hypertension. J Cardiovasc Pharmacol 2000 0.75
33 Expression and characterization of the human endothelin-A-receptor in Pichia pastoris: influence of N-terminal epitope tags. J Cardiovasc Pharmacol 2000 0.75