| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
|
Science
|
1996
|
15.88
|
|
2
|
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.
|
EMBO J
|
1996
|
5.14
|
|
3
|
A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.
|
Development
|
1997
|
5.09
|
|
4
|
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction.
|
Cell
|
1987
|
4.50
|
|
5
|
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.
|
Development
|
1999
|
4.06
|
|
6
|
Structure and function of signal-transducing GTP-binding proteins.
|
Annu Rev Biochem
|
1991
|
3.48
|
|
7
|
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.
|
J Biol Chem
|
1999
|
3.25
|
|
8
|
S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.
|
Cell
|
1990
|
3.09
|
|
9
|
The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.
|
Mol Cell Biol
|
2001
|
2.87
|
|
10
|
IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.
|
Mol Cell Biol
|
1990
|
2.40
|
|
11
|
Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons.
|
Neuron
|
2001
|
2.37
|
|
12
|
Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells.
|
Proc Natl Acad Sci U S A
|
1990
|
2.26
|
|
13
|
Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1.
|
J Biol Chem
|
1996
|
2.22
|
|
14
|
Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins.
|
Proc Natl Acad Sci U S A
|
1987
|
2.15
|
|
15
|
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.
|
Curr Biol
|
1999
|
2.12
|
|
16
|
Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.
|
Proc Natl Acad Sci U S A
|
1990
|
2.08
|
|
17
|
Function of Ras as a molecular switch in signal transduction.
|
J Biol Chem
|
1992
|
2.08
|
|
18
|
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis.
|
Proc Natl Acad Sci U S A
|
2001
|
2.01
|
|
19
|
Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3.
|
Mech Dev
|
2000
|
2.00
|
|
20
|
Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways.
|
Proc Natl Acad Sci U S A
|
1991
|
1.98
|
|
21
|
Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.
|
Proc Natl Acad Sci U S A
|
1991
|
1.96
|
|
22
|
Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6.
|
Mol Cell Neurosci
|
2004
|
1.85
|
|
23
|
MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae.
|
Proc Natl Acad Sci U S A
|
1989
|
1.77
|
|
24
|
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.
|
J Biol Chem
|
2001
|
1.56
|
|
25
|
GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.
|
Proc Natl Acad Sci U S A
|
1993
|
1.48
|
|
26
|
Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord.
|
Exp Neurol
|
2001
|
1.45
|
|
27
|
Requirement of Saccharomyces cerevisiae Ras for completion of mitosis.
|
Science
|
1995
|
1.45
|
|
28
|
Identification of AF-6 and canoe as putative targets for Ras.
|
J Biol Chem
|
1996
|
1.42
|
|
29
|
Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord.
|
J Neurosci
|
2001
|
1.41
|
|
30
|
Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system.
|
Development
|
1999
|
1.37
|
|
31
|
Signal transduction pathways from insulin receptors to Ras. Analysis by mutant insulin receptors.
|
J Biol Chem
|
1994
|
1.33
|
|
32
|
Pax-6 is involved in the specification of hindbrain motor neuron subtype.
|
Development
|
1997
|
1.32
|
|
33
|
Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promoters.
|
Genes Cells
|
1996
|
1.11
|
|
34
|
A novel GTPase-activating protein for R-Ras.
|
J Biol Chem
|
1995
|
1.07
|
|
35
|
Studies on ras proteins. Catalytic properties of normal and activated ras proteins purified in the absence of protein denaturants.
|
Biochim Biophys Acta
|
1988
|
1.04
|
|
36
|
Structures of the genes coding for G-protein alpha subunits from mammalian and yeast cells.
|
Cold Spring Harb Symp Quant Biol
|
1988
|
0.96
|
|
37
|
Suppressors of a gpa1 mutation cause sterility in Saccharomyces cerevisiae.
|
Genetics
|
1988
|
0.87
|
|
38
|
Inhibition of Ras/Raf interaction by anti-oncogenic mutants of neurofibromin, the neurofibromatosis type 1 (NF1) gene product, in cell-free systems.
|
J Biol Chem
|
1995
|
0.86
|
|
39
|
Identification of sonic hedgehog-responsive genes using cDNA microarray.
|
Biochem Biophys Res Commun
|
2001
|
0.85
|
|
40
|
Roles of cell-autonomous mechanisms for differential expression of region-specific transcription factors in neuroepithelial cells.
|
Development
|
1996
|
0.80
|
|
41
|
Biosynthesis and expression of polysialic acid on the neural cell adhesion molecule is predominantly directed by ST8Sia II/STX during in vitro neuronal differentiation.
|
J Biol Chem
|
1996
|
0.77
|
|
42
|
The role of G proteins in yeast signal transduction.
|
Cold Spring Harb Symp Quant Biol
|
1988
|
0.75
|