M Nakafuku

Author PubWeight™ 96.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science 1996 15.88
2 Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 1996 5.14
3 A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 1997 5.09
4 GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction. Cell 1987 4.50
5 Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 1999 4.06
6 Structure and function of signal-transducing GTP-binding proteins. Annu Rev Biochem 1991 3.48
7 Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem 1999 3.25
8 S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell 1990 3.09
9 The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Mol Cell Biol 2001 2.87
10 IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 1990 2.40
11 Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons. Neuron 2001 2.37
12 Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells. Proc Natl Acad Sci U S A 1990 2.26
13 Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1. J Biol Chem 1996 2.22
14 Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins. Proc Natl Acad Sci U S A 1987 2.15
15 Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 1999 2.12
16 Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity. Proc Natl Acad Sci U S A 1990 2.08
17 Function of Ras as a molecular switch in signal transduction. J Biol Chem 1992 2.08
18 BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci U S A 2001 2.01
19 Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3. Mech Dev 2000 2.00
20 Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways. Proc Natl Acad Sci U S A 1991 1.98
21 Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc Natl Acad Sci U S A 1991 1.96
22 Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6. Mol Cell Neurosci 2004 1.85
23 MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1989 1.77
24 Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem 2001 1.56
25 GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells. Proc Natl Acad Sci U S A 1993 1.48
26 Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 2001 1.45
27 Requirement of Saccharomyces cerevisiae Ras for completion of mitosis. Science 1995 1.45
28 Identification of AF-6 and canoe as putative targets for Ras. J Biol Chem 1996 1.42
29 Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord. J Neurosci 2001 1.41
30 Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system. Development 1999 1.37
31 Signal transduction pathways from insulin receptors to Ras. Analysis by mutant insulin receptors. J Biol Chem 1994 1.33
32 Pax-6 is involved in the specification of hindbrain motor neuron subtype. Development 1997 1.32
33 Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promoters. Genes Cells 1996 1.11
34 A novel GTPase-activating protein for R-Ras. J Biol Chem 1995 1.07
35 Studies on ras proteins. Catalytic properties of normal and activated ras proteins purified in the absence of protein denaturants. Biochim Biophys Acta 1988 1.04
36 Structures of the genes coding for G-protein alpha subunits from mammalian and yeast cells. Cold Spring Harb Symp Quant Biol 1988 0.96
37 Suppressors of a gpa1 mutation cause sterility in Saccharomyces cerevisiae. Genetics 1988 0.87
38 Inhibition of Ras/Raf interaction by anti-oncogenic mutants of neurofibromin, the neurofibromatosis type 1 (NF1) gene product, in cell-free systems. J Biol Chem 1995 0.86
39 Identification of sonic hedgehog-responsive genes using cDNA microarray. Biochem Biophys Res Commun 2001 0.85
40 Roles of cell-autonomous mechanisms for differential expression of region-specific transcription factors in neuroepithelial cells. Development 1996 0.80
41 Biosynthesis and expression of polysialic acid on the neural cell adhesion molecule is predominantly directed by ST8Sia II/STX during in vitro neuronal differentiation. J Biol Chem 1996 0.77
42 The role of G proteins in yeast signal transduction. Cold Spring Harb Symp Quant Biol 1988 0.75