K M O'Shaughnessy

Author PubWeight™ 17.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK. Circulation 1999 2.29
2 Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet 1991 2.27
3 A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. J Biol Chem 2001 1.19
4 Greater inotropic and cyclic AMP responses evoked by noradrenaline through Arg389 beta 1-adrenoceptors versus Gly389 beta 1-adrenoceptors in isolated human atrial myocardium. Br J Pharmacol 2003 1.13
5 The functional significance of genetic variation within the beta-adrenoceptor. Br J Clin Pharmacol 2005 0.93
6 An unusual complication of carcinoma of the caecum. Postgrad Med J 2000 0.90
7 Thromboxane A2 biosynthesis in acute asthma and after antigen challenge. Am Rev Respir Dis 1991 0.89
8 Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography. Lancet 1996 0.87
9 A comparative study in atopic subjects with asthma of the effects of salmeterol and salbutamol on allergen-induced bronchoconstriction, increase in airway reactivity, and increase in urinary leukotriene E4 excretion. J Allergy Clin Immunol 1992 0.87
10 Inhibition of nitric oxide synthesis in vascular smooth muscle by retinoids. Br J Pharmacol 1994 0.84
11 The influence of central noradrenergic function on 5-HT2-mediated head-twitch responses in mice: possible implications for the actions of antidepressant drugs. Psychopharmacology (Berl) 1986 0.81
12 Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II. J Hum Hypertens 2010 0.81
13 Confirmation of a role for the 389R>G beta-1 adrenoceptor polymorphism on exercise capacity in heart failure. Heart 2005 0.78
14 Hypophysectomy alters both 5-hydroxytryptamine- and alpha 2-adrenoceptor-mediated behavioural changes in the rat. Eur J Pharmacol 1983 0.78
15 Failure to detect linkage of preeclampsia to the region of the NOS3 locus on chromosome 7q. Am J Hum Genet 1999 0.77
16 Glycerol-enhanced mini-polyacrylamide gel electrophoresis for the separation of differentially expressed DNA fragments in cDNA representational difference analysis. Electrophoresis 2001 0.77
17 Hyperaldosteronism: recent concepts, diagnosis, and management. Postgrad Med J 2001 0.76
18 Thrombophilic polymorphisms in pre-eclampsia: altered frequency of the functional 98C>T polymorphism of glycoprotein IIIa. J Med Genet 2001 0.75