Published in J Neurosci on December 15, 2001
Crucial role of sodium channel fast inactivation in muscle fibre inexcitability in a rat model of critical illness myopathy. J Physiol (2003) 1.29
Neuroexcitatory actions of Tamiflu and its carboxylate metabolite. Neurosci Lett (2007) 1.22
Voltage-gated Na+ channels: multiplicity of expression, plasticity, functional implications and pathophysiological aspects. Eur Biophys J (2004) 1.09
Sialyltransferase regulates nervous system function in Drosophila. J Neurosci (2010) 1.05
Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation. J Electrocardiol (2009) 1.04
Voltage-Gated Na+ Channels: Not Just for Conduction. Cold Spring Harb Perspect Biol (2016) 1.01
N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons. J Biol Chem (2012) 0.97
Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardium. J Gen Physiol (2006) 0.96
The role of protein N-glycosylation in neural transmission. Glycobiology (2014) 0.95
β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells. Front Cell Neurosci (2013) 0.92
Functional features of trans-differentiated hair cells mediated by Atoh1 reveals a primordial mechanism. J Neurosci (2012) 0.92
Mechanism of sodium channel NaV1.9 potentiation by G-protein signaling. J Gen Physiol (2013) 0.90
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation. J Neurosci (2013) 0.89
N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor. J Biol Chem (2012) 0.89
Channel activation voltage alone is directly altered in an isoform-specific manner by Na(v1.4) and Na(v1.5) cytoplasmic linkers. J Membr Biol (2004) 0.89
Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels. Diabetes (2013) 0.87
N-glycosylation in regulation of the nervous system. Adv Neurobiol (2014) 0.83
Glycosylation of the sodium channel β4 subunit is developmentally regulated and involves in neuritic degeneration. Int J Biol Sci (2012) 0.82
Hereditary Inclusion Body Myopathy (HIBM2). Gene Regul Syst Bio (2009) 0.82
Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice. J Biol Chem (2014) 0.81
Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes. Front Pharmacol (2015) 0.80
Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families. PLoS One (2016) 0.80
Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly. J Biol Chem (2014) 0.78
Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating. Biochim Biophys Acta (2014) 0.75
Direct Current-Induced Calcium Trafficking in Different Neuronal Preparations. Neural Plast (2016) 0.75
Location, location, location?: is the pain of diabetic neuropathy generated by hyperactive sensory neurons? Diabetes (2013) 0.75
Mining the virgin land of neurotoxicology: a novel paradigm of neurotoxic peptides action on glycosylated voltage-gated sodium channels. J Toxicol (2012) 0.75
Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder. Neurobiol Dis (2016) 0.75
Nomenclature of voltage-gated sodium channels. Neuron (2000) 3.10
Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. J Neurophysiol (2001) 3.01
A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci (1999) 2.73
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy. Proc Natl Acad Sci U S A (1998) 2.44
Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain (2005) 2.32
Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. J Neurosci (1998) 2.30
Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J Neurosci (1997) 2.26
Determinants of conduction velocity in myelinated nerve fibers. Muscle Nerve (1980) 2.14
A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience (2001) 2.14
Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. Brain Res Mol Brain Res (1996) 2.12
Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain Res Mol Brain Res (1997) 2.12
Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. J Neurosci (1992) 2.11
Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res (1992) 2.02
Hypergraphia in temporal lobe epilepsy. Neurology (1974) 1.87
Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. J Neurosci (2001) 1.87
Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. J Neurophysiol (2001) 1.83
Relative conduction velocities of small myelinated and non-myelinated fibres in the central nervous system. Nat New Biol (1972) 1.80
Group II introns deleted for multiple substructures retain self-splicing activity. Mol Cell Biol (1992) 1.77
Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability. Neurology (2012) 1.73
Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). J Biol Chem (2001) 1.71
NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders. J Neurosci (2008) 1.70
Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Arch Neurol (2005) 1.69
SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport (1998) 1.61
Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord. J Neurosci (1998) 1.60
Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. J Neurosci (1996) 1.59
Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. J Neurophysiol (1999) 1.53
Conduction velocity and spike configuration in myelinated fibres: computed dependence on internode distance. J Neurol Neurosurg Psychiatry (1977) 1.52
Distribution of sodium channels in chronically demyelinated spinal cord axons: immuno-ultrastructural localization and electrophysiological observations. Brain Res (1991) 1.50
Activity-dependent modulation of excitability: implications for axonal physiology and pathophysiology. Muscle Nerve (1994) 1.49
Organization of ion channels in the myelinated nerve fiber. Science (1985) 1.44
Rat optic nerve: electrophysiological, pharmacological and anatomical studies during development. Brain Res (1982) 1.42
Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy. Muscle Nerve (1999) 1.41
Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Res Mol Brain Res (1999) 1.40
The pentapeptide QYNAD does not block voltage-gated sodium channels. Neurology (2003) 1.40
The interictal behavior syndrome of temporal lobe epilepsy. Arch Gen Psychiatry (1975) 1.38
Acute confusional states with right middle cerebral artery infarctions. J Neurol Neurosurg Psychiatry (1976) 1.37
Demyelinating diseases--new pathological insights, new therapeutic targets. N Engl J Med (1998) 1.37
Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron. Mol Cell Biol (1995) 1.37
Conduction in myelinated, unmyelinated, and demyelinated fibers. Arch Neurol (1977) 1.35
Effects of extracellular potassium concentration on the excitability of the parallel fibres of the rat cerebellum. J Physiol (1983) 1.32
Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy. Proc Natl Acad Sci U S A (1996) 1.32
Regional differentiation of the axon: a review with special reference to the concept of the multiplex neuron. Brain Res (1972) 1.30
Delayed depolarization and slow sodium currents in cutaneous afferents. J Neurophysiol (1994) 1.29
Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain (1999) 1.27
Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin-deficient rat. Proc Natl Acad Sci U S A (1994) 1.26
Selective loss of slow and enhancement of fast Na+ currents in cutaneous afferent dorsal root ganglion neurones following axotomy. Neurobiol Dis (1995) 1.26
Slow sodium conductances of dorsal root ganglion neurons: intraneuronal homogeneity and interneuronal heterogeneity. J Neurophysiol (1994) 1.26
Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. Proc Natl Acad Sci U S A (1993) 1.25
Integrative properties and design principles of axons. Int Rev Neurobiol (1975) 1.24
Modulation of impulse conduction along the axonal tree. Annu Rev Biophys Bioeng (1980) 1.24
Ion channel organization of the myelinated fiber. Trends Neurosci (1990) 1.23
International spinal cord injury pain classification: part I. Background and description. March 6-7, 2009. Spinal Cord (2011) 1.23
Conduction through demyelinated plaques in multiple sclerosis: computer simulations of facilitation by short internodes. J Neurol Neurosurg Psychiatry (1978) 1.19
Compound action potential of nerve recorded by suction electrode: a theoretical and experimental analysis. Brain Res (1991) 1.16
Variations in conduction velocity and excitability following single and multiple impulses of visual callosal axons in the rabbit. Exp Neurol (1976) 1.15
Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy. J Neurosci (2000) 1.14
Modulation of parallel fiber excitability by postsynaptically mediated changes in extracellular potassium. Science (1981) 1.14
Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. J Neurophysiol (1998) 1.13
Peripheral nerve axon processes sharing common myelin sheaths. Brain Res (1968) 1.13
In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia (1989) 1.12
Sodium channel mRNAs I, II and III in the CNS: cell-specific expression. Brain Res Mol Brain Res (1994) 1.11
Electrogenic pump (Na+/K(+)-ATPase) activity in rat optic nerve. Neuroscience (1990) 1.11
The association of the supernormal period and the depolarizing afterpotential in myelinated frog and rat sciatic nerve. Neuroscience (1987) 1.09
Functional differences between 4-aminopyridine and tetraethylammonium-sensitive potassium channels in myelinated axons. Neurosci Lett (1987) 1.08
Direct interaction with contactin targets voltage-gated sodium channel Na(v)1.9/NaN to the cell membrane. J Biol Chem (2001) 1.08
Activation and inactivation of the voltage-gated sodium channel: role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation. J Neurosci (1999) 1.08
Na(v)1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons. Brain Res Mol Brain Res (2002) 1.08
Morphology and physiology of visual callosal axons: evidence for a supernormal period in central myelinated axons. Brain Res (1976) 1.08
Variation in conduction velocity during the relative refractory and supernormal periods: a mechanism for impulse entrainment in central axons. Exp Neurol (1979) 1.08
Chronic fatigue syndrome and channelopathies. Med Hypotheses (2000) 1.07
Morphological correlates of functional differentiation of nodes of Ranvier along single fibers in the neurogenic electric organ of the knife fish Stern archus. J Cell Biol (1972) 1.07
Regulation of mouse skeletal muscle L-type Ca2+ channel by activation of the insulin-like growth factor-1 receptor. J Neurosci (1997) 1.07
Absence of potassium conductance in central myelinated axons. Nature (1980) 1.06
Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. J Neurosci (2000) 1.06
Reorganization of the axon membrane in demyelinated peripheral nerve fibers: morphological evidence. Science (1980) 1.06
Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis. Proc Natl Acad Sci U S A (2000) 1.05
Membranes, myelin, and the pathophysiology of multiple sclerosis. N Engl J Med (1982) 1.05
Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proc Natl Acad Sci U S A (1999) 1.04
Observations on impulse conduction along central axons. Proc Natl Acad Sci U S A (1975) 1.04
Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons. FEBS Lett (1999) 1.04
Differences between mammalian ventral and dorsal spinal roots in response to blockade of potassium channels during maturation. Proc R Soc Lond B Biol Sci (1985) 1.04
Characteristics of interhemispheric impulse conduction between prelunate gyri of the rhesus monkey. Exp Brain Res (1978) 1.03
Can robots patch-clamp as well as humans? Characterization of a novel sodium channel mutation. J Physiol (2010) 1.03
Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors. Neuroreport (2000) 1.02
Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibers. J Neurophysiol (1988) 1.02
Closely spaced nodes of Ranvier in the teleost brain. Nature (1970) 1.01