Published in Mol Vis on December 02, 2001
Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol (2005) 2.38
Role of growth factors and the wound healing response in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2003) 1.64
Choroid development and feasibility of choroidal imaging in the preterm and term infants utilizing SD-OCT. Invest Ophthalmol Vis Sci (2013) 1.64
PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF. PLoS Genet (2014) 1.52
Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1. J Lipid Res (2010) 1.45
Expression and role of VEGF in the adult retinal pigment epithelium. Invest Ophthalmol Vis Sci (2011) 1.21
Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature. J Neurochem (2010) 1.01
The choroid as a sclera growth regulator. Exp Eye Res (2013) 0.92
The retinal pigment epithelium of the eye regulates the development of scleral cartilage. Dev Biol (2010) 0.84
Increased density of retinal pigment epithelium in cd81-/- mice. J Cell Biochem (2004) 0.83
Deciphering combinations of PI3K/AKT/mTOR pathway drugs augmenting anti-angiogenic efficacy in vivo. PLoS One (2014) 0.80
Epithelial-mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy. Histochem Cell Biol (2016) 0.79
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development (2012) 0.79
Focal choroidal excavation: a preliminary interpretation based on clinic and review. Int J Ophthalmol (2015) 0.77
The effects of a CD81 null mutation on retinal pigment epithelium in mice. Neurochem Res (2010) 0.77
Identification of a synergistic interaction between endothelial cells and retinal pigment epithelium. J Cell Mol Med (2017) 0.76
Impact of Intravitreal Injection of Bevacizumab (Avastin) on Rabbit's Choroid and Retina. Middle East Afr J Ophthalmol (2008) 0.75
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest (1997) 5.19
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling. Nat Genet (2001) 3.86
Oncogenesis of the lens in transgenic mice. Science (1987) 3.40
Reversal of left-right asymmetry: a situs inversus mutation. Science (1993) 2.56
Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet (1999) 2.54
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat Med (2000) 2.29
Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet (1999) 2.29
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. Proc Natl Acad Sci U S A (1985) 2.22
Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res (1990) 2.13
A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse. Nat Genet (2000) 1.95
Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature (2002) 1.95
Cloning of inv, a gene that controls left/right asymmetry and kidney development. Nature (1998) 1.90
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival. Proc Natl Acad Sci U S A (2001) 1.83
Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development (2000) 1.75
Calmodulin-induced early-onset diabetes in transgenic mice. Cell (1989) 1.71
Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. J Cell Biol (1992) 1.70
Tissue-specific expression in transgenic mice of a fused gene containing RSV terminal sequences. Science (1986) 1.64
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development. Development (2000) 1.57
Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice. Development (1995) 1.53
Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice. Proc Natl Acad Sci U S A (1992) 1.44
Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest (1998) 1.40
The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Dev Biol (1998) 1.37
Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme. J Biol Chem (1991) 1.37
Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice. Development (1998) 1.36
Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys. Am J Pathol (1993) 1.34
Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice. Proc Natl Acad Sci U S A (1986) 1.34
The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice. Mol Cell Biol (1994) 1.27
Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis. Development (2000) 1.23
Expression of yeast hexokinase in pancreatic beta cells of transgenic mice reduces blood glucose, enhances insulin secretion, and decreases diabetes. Proc Natl Acad Sci U S A (1992) 1.23
Differential expression of alpha A- and alpha B-crystallin during murine ocular development. Invest Ophthalmol Vis Sci (1996) 1.22
Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development (1995) 1.22
Characterization of five members of the actin gene family in the sea urchin. Biochim Biophys Acta (1981) 1.20
Prenatal lethality in a transgenic mouse line is the result of a chromosomal translocation. Proc Natl Acad Sci U S A (1988) 1.17
Tissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein. J Biol Chem (1990) 1.16
Endogenous and ectopic gland induction by FGF-10. Dev Biol (2000) 1.15
Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome. Genomics (1999) 1.13
Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice. Dev Biol (1998) 1.11
Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation. Development (2001) 1.11
Patterning the optic neuroepithelium by FGF signaling and Ras activation. Development (2001) 1.09
Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation. Development (2001) 1.05
Lens-specific expression of PDGF-A alters lens growth and development. Dev Biol (1996) 1.02
Anomalous development of the hepatobiliary system in the Inv mouse. Hepatology (1999) 1.02
Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo. EMBO J (1995) 1.02
Transgenic mice carrying a PSArasT24 hybrid gene develop salivary gland and gastrointestinal tract neoplasms. Lab Invest (1995) 0.98
Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues. Dev Biol (1999) 0.98
Photoreceptor-specific activity of the human interphotoreceptor retinoid-binding protein (IRBP) promoter in transgenic mice. Exp Eye Res (1992) 0.98
Drosophila P element integration in the mouse. Dev Biol (1985) 0.97
Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc Natl Acad Sci U S A (1999) 0.96
Misexpression of IGF-I in the mouse lens expands the transitional zone and perturbs lens polarization. Mech Dev (2001) 0.96
Lens-specific expression of PDGF-A in transgenic mice results in retinal astrocytic hamartomas. Invest Ophthalmol Vis Sci (1996) 0.95
Ectopic gland induction by lens-specific expression of keratinocyte growth factor (FGF-7) in transgenic mice. Mech Dev (1999) 0.95
Symplastic spermatids (sys): a recessive insertional mutation in mice causing a defect in spermatogenesis. Proc Natl Acad Sci U S A (1990) 0.95
Insertional inactivation of the downless gene in a family of transgenic mice. Mol Biol Med (1989) 0.93
TGF alpha can act as a chemoattractant to perioptic mesenchymal cells in developing mouse eyes. Development (1995) 0.93
Lens-specific VEGF-A expression induces angioblast migration and proliferation and stimulates angiogenic remodeling. Dev Biol (2000) 0.93
Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein. Oncogene (1996) 0.92
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice. J Biol Chem (1992) 0.91
Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2. Invest Ophthalmol Vis Sci (2000) 0.91
Inhibition of cell death by lens-specific overexpression of bcl-2 in transgenic mice. Dev Genet (1997) 0.89
Expression of the rasT24 oncogene in the ciliary body pigment epithelium and retinal pigment epithelium results in hyperplasia, adenoma, and adenocarcinoma. Am J Pathol (1993) 0.88
Use of a simplified single-site PCR to facilitate cloning of genomic DNA sequences flanking a transgene integration site. PCR Methods Appl (1991) 0.87
Elevated TGFbeta signaling inhibits ocular vascular development. Dev Biol (2001) 0.86
YAC rescue of downless locus mutations in mice. Mamm Genome (1998) 0.85
Dominant dysplasia of the lens in transgenic mice expressing the dbl oncogene. New Biol (1991) 0.84
Targeted overexpression of an inactive calmodulin that binds Ca2+ to the mouse pancreatic beta-cell results in impaired secretion and chronic hyperglycemia. Endocrinology (1995) 0.82
Trilateral tumors in four different lines of transgenic mice expressing SV40 T-antigen. Invest Ophthalmol Vis Sci (1996) 0.81
Insertional mutation that causes acrosomal hypo-development: its relationship to sperm head shaping. Anat Rec (1994) 0.81
Retina-specific expression from the IRBP promoter in transgenic mice is conferred by 212 bp of the 5'-flanking region. Biochem Biophys Res Commun (1991) 0.80
Expression of testis angiotensin-converting enzyme is mediated by a cyclic AMP responsive element. Lab Invest (1997) 0.80
5'-flanking sequences of the human HPRT gene direct neuronal expression in the brain of transgenic mice. J Neurosci Res (1994) 0.80
Testis structure in the sys (symplastic spermatids) mouse. Am J Anat (1991) 0.79
Identification of a retina-specific footprint within the retina-specific regulatory region of the human interphotoreceptor retinoid-binding protein gene. Biochem Biophys Res Commun (1994) 0.77
Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo. J Biochem (1999) 0.77
Promoter sequences of murine alpha A crystallin, murine alpha 2(I) collagen or of avian sarcoma virus genes linked to the bacterial chloramphenicol acetyl transferase gene direct tissue-specific patterns of chloramphenicol acetyl transferase expression in transgenic mice. Cold Spring Harb Symp Quant Biol (1985) 0.77
Right and left go dHAND and eHAND. Nat Genet (1997) 0.75
Crystallin genes: lens specificity of the murine alpha A-crystallin gene. Environ Health Perspect (1987) 0.75
Tissue specific expression of testis angiotensin converting enzyme is not determined by the -32 nonconsensus TATA motif. Biochem Biophys Res Commun (1996) 0.75