Reinhard Brossmer

Author PubWeight™ 12.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound. J Exp Med 2002 1.35
2 Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin. Structure 2003 1.32
3 Versatile biosynthetic engineering of sialic acid in living cells using synthetic sialic acid analogues. J Biol Chem 2001 1.22
4 The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design. Biochem J 2006 1.02
5 Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin. J Mol Biol 2006 0.92
6 Expression of sialyltransferase activity on intact human neutrophils. J Leukoc Biol 2008 0.87
7 Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells. Glycoconj J 2005 0.85
8 Purification and characterization of 9-O-acetylated sialoglycoproteins from leukemic cells and their potential as immunological tool for monitoring childhood acute lymphoblastic leukemia. Glycobiology 2004 0.82
9 Human dendritic cells contain cell surface sialyltransferase activity. Immunol Lett 2010 0.81
10 Targeting of CD22-positive B-cell lymphoma cells by synthetic divalent sialic acid analogues. Eur J Immunol 2012 0.80
11 Discovery of multifold modified sialosides as human CD22/Siglec-2 ligands with nanomolar activity on B-cells. ACS Chem Biol 2014 0.80
12 The myelin-associated glycoprotein inhibitor BENZ induces outgrowth and survival of rat dorsal root ganglion cell cultures. J Neurosci Res 2007 0.76
13 Successful prediction of substrate-binding pocket in SLC17 transporter sialin. J Biol Chem 2012 0.75