Published in Immunity on December 01, 2001
Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. Genome Biol (2008) 2.25
Immunity and other defenses in pea aphids, Acyrthosiphon pisum. Genome Biol (2010) 2.09
The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila. PLoS Pathog (2012) 1.86
Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. EMBO J (2005) 1.79
Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria. Genetics (2006) 1.44
Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response. Proc Natl Acad Sci U S A (2009) 1.40
Elevated polymorphism and divergence in the class C scavenger receptors of Drosophila melanogaster and D. simulans. Genetics (2005) 1.34
The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila. Proc Natl Acad Sci U S A (2006) 1.20
Drosophila as a model system to unravel the layers of innate immunity to infection. Open Biol (2012) 1.20
Genomic RNAi screening in Drosophila S2 cells: what have we learned about host-pathogen interactions? Curr Opin Microbiol (2008) 1.15
Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogaster. PLoS Genet (2012) 1.14
Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections. PLoS One (2011) 1.14
Glc1.8 from Microplitis demolitor bracovirus induces a loss of adhesion and phagocytosis in insect high five and S2 cells. J Virol (2005) 1.13
Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans. Genetics (2005) 1.08
Innate immunity in Drosophila: Pathogens and pathways. Insect Sci (2008) 1.04
Participation of a galactose-specific C-type lectin in Drosophila immunity. Biochem J (2006) 1.02
Gene expression profiling of Spodoptera frugiperda hemocytes and fat body using cDNA microarray reveals polydnavirus-associated variations in lepidopteran host genes transcript levels. BMC Genomics (2006) 1.01
PTP-H2 and PTP-H3 from Microplitis demolitor Bracovirus localize to focal adhesions and are antiphagocytic in insect immune cells. J Virol (2006) 0.97
Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer's disease. Int J Alzheimers Dis (2012) 0.96
How the insect immune system interacts with an obligate symbiotic bacterium. Proc Biol Sci (2010) 0.96
Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease. Int J Hypertens (2010) 0.95
Recognition of pathogenic microbes by the Drosophila phagocytic pattern recognition receptor Eater. J Biol Chem (2011) 0.92
Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides. PLoS Pathog (2014) 0.90
Post-transcriptional Regulation of Genes Encoding Anti-microbial Peptides in Drosophila. J Biol Chem (2009) 0.90
Drosophila hematopoiesis: Markers and methods for molecular genetic analysis. Methods (2014) 0.89
Immune-related transcriptome of Coptotermes formosanus Shiraki workers: the defense mechanism. PLoS One (2013) 0.89
Seeking common pathophysiology in asthma, atopy and sinusitis. Trends Immunol (2011) 0.89
Scavenger receptor structure and function in health and disease. Cells (2015) 0.88
Innate immune responses of Drosophila melanogaster are altered by spaceflight. PLoS One (2011) 0.87
Independent recognition of Staphylococcus aureus by two receptors for phagocytosis in Drosophila. J Biol Chem (2012) 0.87
Expression of immune-response genes in lepidopteran host is suppressed by venom from an endoparasitoid, Pteromalus puparum. BMC Genomics (2010) 0.85
Deconstructing host-pathogen interactions in Drosophila. Dis Model Mech (2011) 0.84
Scavenger receptor mediates systemic RNA interference in ticks. PLoS One (2011) 0.83
C-type lectin binds to β-integrin to promote hemocytic phagocytosis in an invertebrate. J Biol Chem (2013) 0.83
Haplotype structure and expression divergence at the Drosophila cellular immune gene eater. Mol Biol Evol (2010) 0.82
The Drosophila melanogaster host model. J Oral Microbiol (2012) 0.82
A neuron-specific antiviral mechanism prevents lethal flaviviral infection of mosquitoes. PLoS Pathog (2015) 0.82
Quantitative profiling of Drosophila melanogaster Dscam1 isoforms reveals no changes in splicing after bacterial exposure. PLoS One (2014) 0.82
Drosophila as a model for antiviral immunity. World J Biol Chem (2010) 0.81
Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila. J Biol Chem (2014) 0.80
Tissue-enriched expression profiles in Aedes aegypti identify hemocyte-specific transcriptome responses to infection. Insect Biochem Mol Biol (2012) 0.80
Genome-wide characterization and expression profiling of immune genes in the diamondback moth, Plutella xylostella (L.). Sci Rep (2015) 0.79
The characterization of the Phlebotomus papatasi transcriptome. Insect Mol Biol (2013) 0.79
Functional characterization of the infection-inducible peptide Edin in Drosophila melanogaster. PLoS One (2012) 0.78
Loss of the tumor suppressor Pten promotes proliferation of Drosophila melanogaster cells in vitro and gives rise to continuous cell lines. PLoS One (2012) 0.78
Knockdown of SCF(Skp2) function causes double-parked accumulation in the nucleus and DNA re-replication in Drosophila plasmatocytes. PLoS One (2013) 0.77
Cytoplasmic actin is an extracellular insect immune factor which is secreted upon immune challenge and mediates phagocytosis and direct killing of bacteria, and is a Plasmodium Antagonist. PLoS Pathog (2015) 0.77
Drosophila blood as a model system for stress sensing mechanisms. BMB Rep (2015) 0.77
Comparative transcriptomic analysis of immune responses of the migratory locust, Locusta migratoria, to challenge by the fungal insect pathogen, Metarhizium acridum. BMC Genomics (2015) 0.77
The Drosophila CD36 Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging. PLoS Pathog (2016) 0.76
Identification of Genes Relevant to Pesticides and Biology from Global Transcriptome Data of Monochamus alternatus Hope (Coleoptera: Cerambycidae) Larvae. PLoS One (2016) 0.75
Scavenger Receptor C Mediates Phagocytosis of White Spot Syndrome Virus and Restricts Virus Proliferation in Shrimp. PLoS Pathog (2016) 0.75
Adult Drosophila melanogaster evolved for antibacterial defense invest in infection-induced expression of both humoral and cellular immunity genes. BMC Res Notes (2011) 0.75
A Mesh-Duox pathway regulates homeostasis in the insect gut. Nat Microbiol (2017) 0.75
Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet (2001) 13.32
Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging (1991) 11.44
Phylogenetic perspectives in innate immunity. Science (1999) 9.42
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet (2000) 8.33
Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science (1996) 8.29
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature (2000) 7.37
Sequence complexity of disordered protein. Proteins (2001) 6.97
Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell (2000) 6.81
A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature (2000) 6.12
Culture-independent diagnosis of Chlamydia trachomatis using monoclonal antibodies. N Engl J Med (1984) 6.08
Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol (2001) 5.17
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell (2001) 4.92
Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma. Eur Respir J (2009) 4.54
Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature (1990) 4.52
Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest (1994) 4.39
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell (1993) 4.30
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol (2001) 4.25
A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc Natl Acad Sci U S A (1997) 4.17
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid. Nature (1998) 4.09
Clonal and antigenic analysis of serogroup A Neisseria meningitidis with particular reference to epidemiological features of epidemic meningitis in the People's Republic of China. Infect Immun (1992) 4.02
Collagen polymorphism: characterization of molecules with the chain composition (alpha 1 (3)03 in human tissues. Science (1974) 3.95
Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry (1997) 3.90
Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother (2004) 3.69
Mutations altering the moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle. EMBO J (1999) 3.67
Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature (1995) 3.58
Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene. Proc Natl Acad Sci U S A (1999) 3.56
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep (2001) 3.55
Ordered restriction maps of Saccharomyces cerevisiae chromosomes constructed by optical mapping. Science (1993) 3.54
Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature (1997) 3.47
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol Cell Biol (1994) 3.46
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine. J Virol (1992) 3.46
Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum. J Exp Med (1985) 3.44
Expression cloning of SR-BI, a CD36-related class B scavenger receptor. J Biol Chem (1994) 3.29
Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant. Cell (1986) 3.25
RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J Exp Med (1992) 3.25
Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science (2001) 3.23
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene (1999) 3.23
Incidence of open-angle glaucoma: the Barbados Eye Studies. The Barbados Eye Studies Group. Arch Ophthalmol (2001) 3.20
Hypertrophic gastropathy in Helicobacter felis-infected wild-type C57BL/6 mice and p53 hemizygous transgenic mice. Gastroenterology (1996) 3.15
The human mannose-binding protein functions as an opsonin. J Exp Med (1989) 3.15
Age-related changes in the collagen network and toughness of bone. Bone (2002) 3.13
Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci (1999) 3.10
Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: a model of helicobacter-induced carcinogenesis. Infect Immun (1996) 3.09
Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proc Natl Acad Sci U S A (1999) 3.07
Recognition and plasma clearance of endotoxin by scavenger receptors. Nature (1991) 3.00
Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins. J Cell Biol (1979) 2.98
Familial risk in testicular cancer as a clue to a heritable and environmental aetiology. Br J Cancer (2004) 2.97
Cellular markers that distinguish the phases of hemangioma during infancy and childhood. J Clin Invest (1994) 2.97
A randomized, controlled effectiveness trial of an AIDS prevention program for low-income African-American youths. Arch Pediatr Adolesc Med (1996) 2.95
cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem (1994) 2.95
Infection of the surgical site after arthroplasty of the hip. J Bone Joint Surg Br (2005) 2.94
Effectiveness of laser therapy and topical desensitising agents in treating dentine hypersensitivity: a systematic review. J Oral Rehabil (2011) 2.91
Dedifferentiation of epidermal cells to stem cells in vivo. Lancet (2001) 2.90
Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia. J Exp Med (1981) 2.89
A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell (1993) 2.80
An extreme distortion of the Van Allen belt arising from the 'Hallowe'en' solar storm in 2003. Nature (2004) 2.76
Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses (2001) 2.75
Determination of the MRI contrast agent concentration time course in vivo following bolus injection: effect of equilibrium transcytolemmal water exchange. Magn Reson Med (2000) 2.75
Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature (1991) 2.73
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo. J Exp Med (1997) 2.71
PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat Cell Biol (2001) 2.70
Diffusion tensor imaging of acute mild traumatic brain injury in adolescents. Neurology (2008) 2.67
Adhesion formation after previous caesarean section-a meta-analysis and systematic review. BJOG (2010) 2.66
Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis. Proc Natl Acad Sci U S A (1999) 2.58
The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids. J Biol Chem (1995) 2.58
Management and outcome patterns for adult Pneumocystis carinii pneumonia, 1985 to 1995: comparison of HIV-associated cases to other immunocompromised states. Chest (2000) 2.57
Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics (1992) 2.55
Local opsonization by secreted macrophage complement components. Role of receptors for complement in uptake of zymosan. J Exp Med (1984) 2.53
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med (1995) 2.52
Adverse impact of surgical site infections in English hospitals. J Hosp Infect (2005) 2.51
Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature (1999) 2.50
Computed tomography imaging features and classification of isolated dissection of the superior mesenteric artery. Eur J Vasc Endovasc Surg (2013) 2.50
Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor. J Exp Med (1993) 2.49
Development of a culturally, theoretically and developmentally based survey instrument for assessing risk behaviors among African-American early adolescents living in urban low-income neighborhoods. AIDS Educ Prev (1995) 2.48
Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus. Infect Immun (1996) 2.47
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem (1999) 2.43
Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem (1998) 2.42
Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proc Natl Acad Sci U S A (1998) 2.40
Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II. Nature (1990) 2.40
Effectiveness of the 40 adolescent AIDS-risk reduction interventions: a quantitative review. J Adolesc Health (1997) 2.37
Device-related sources of bacteraemia in English hospitals--opportunities for the prevention of hospital-acquired bacteraemia. J Hosp Infect (2003) 2.33
MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells. J Immunol (2001) 2.33
Incidence trends and risk factors of carcinoid tumors: a nationwide epidemiologic study from Sweden. Cancer (2001) 2.32
Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene (2008) 2.31
The mannose receptor is a pattern recognition receptor involved in host defense. Curr Opin Immunol (1998) 2.31
LAI inversion algorithm based on directional reflectance kernels. J Environ Manage (2006) 2.31
Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells. Immunity (1996) 2.30
Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. Science (1999) 2.29
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. J Biol Chem (1994) 2.28
Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc Natl Acad Sci U S A (1987) 2.25
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J Exp Med (1995) 2.24
An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. Proc Natl Acad Sci U S A (1990) 2.24
Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem (1999) 2.23
The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid. Proc Natl Acad Sci U S A (1994) 2.22
Equilibrium transcytolemmal water-exchange kinetics in skeletal muscle in vivo. Magn Reson Med (1999) 2.21
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J Biol Chem (1994) 2.20
An anchoring theory of lightness perception. Psychol Rev (1999) 2.20
Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. Mol Cell (1998) 2.18
Surveillance of the first case of human avian influenza A (H7N9) virus in Beijing, China. Infection (2013) 2.18
A long-lived relativistic electron storage ring embedded in Earth's outer Van Allen belt. Science (2013) 2.16