Published in Exp Cell Res on January 15, 2002
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev (2004) 5.11
Chromosome territories. Cold Spring Harb Perspect Biol (2010) 5.00
The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev (2006) 3.91
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment. J Cell Biol (2008) 3.13
Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J Cell Biol (2006) 2.63
Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei. J Cell Biol (2004) 2.43
Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. J Cell Biol (2002) 2.40
Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol (2006) 2.12
Coregulated human globin genes are frequently in spatial proximity when active. J Cell Biol (2006) 2.12
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res (2003) 1.94
Spatial organization of active and inactive genes and noncoding DNA within chromosome territories. J Cell Biol (2002) 1.92
The three-dimensional structure of human interphase chromosomes is related to the transcriptome map. Mol Cell Biol (2007) 1.82
Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5. Mol Cell Biol (2006) 1.81
Coordinate gene regulation during hematopoiesis is related to genomic organization. PLoS Biol (2007) 1.77
Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions. J Cell Biol (2004) 1.74
Complexity of chromatin folding is captured by the strings and binders switch model. Proc Natl Acad Sci U S A (2012) 1.73
A genetic analysis of chromosome territory looping: diverse roles for distal regulatory elements. Chromosome Res (2003) 1.67
Remodeling of three-dimensional organization of the nucleus during terminal keratinocyte differentiation in the epidermis. J Invest Dermatol (2013) 1.51
The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture. Chromosoma (2005) 1.45
Radial chromatin positioning is shaped by local gene density, not by gene expression. Chromosoma (2007) 1.45
Histone modifications and nuclear architecture: a review. J Histochem Cytochem (2008) 1.42
p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol (2011) 1.39
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts. Genome Biol (2010) 1.38
Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region. PLoS Genet (2008) 1.38
Mobility and immobility of chromatin in transcription and genome stability. Curr Opin Genet Dev (2007) 1.37
Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol (2012) 1.32
Lack of bystander activation shows that localization exterior to chromosome territories is not sufficient to up-regulate gene expression. Genome Res (2009) 1.26
The spatial repositioning of adipogenesis genes is correlated with their expression status in a porcine mesenchymal stem cell adipogenesis model system. Chromosoma (2009) 1.20
Stable morphology, but dynamic internal reorganisation, of interphase human chromosomes in living cells. PLoS One (2010) 1.17
4D chromatin dynamics in cycling cells: Theodor Boveri's hypotheses revisited. Nucleus (2010) 1.16
Ectopic nuclear reorganisation driven by a Hoxb1 transgene transposed into Hoxd. J Cell Sci (2008) 1.14
Differences in centromere positioning of cycling and postmitotic human cell types. Chromosoma (2004) 1.12
Gene expression within a dynamic nuclear landscape. EMBO J (2006) 1.10
Chromosome territory reorganization in a human disease with altered DNA methylation. Proc Natl Acad Sci U S A (2007) 1.06
Preservation of large-scale chromatin structure in FISH experiments. Chromosoma (2006) 1.02
A rapid simple approach to quantify chromosome conformation capture. Nucleic Acids Res (2009) 1.01
Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. EMBO J (2006) 1.00
Cell type-specific chromatin decondensation of a metabolic gene cluster in oats. Plant Cell (2009) 0.99
Epigenetic regulation of skin: focus on the Polycomb complex. Cell Mol Life Sci (2012) 0.99
Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei. J Cell Sci (2008) 0.99
The DNA-based structure of human chromosome 5 in interphase. Am J Hum Genet (2002) 0.97
Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells. PLoS One (2007) 0.97
The architecture of chicken chromosome territories changes during differentiation. BMC Cell Biol (2004) 0.96
Structure and epigenetics of nucleoli in comparison with non-nucleolar compartments. J Histochem Cytochem (2009) 0.93
Sites that direct nuclear compartmentalization are near the 5' end of the mouse immunoglobulin heavy-chain locus. Mol Cell Biol (2005) 0.93
Chromatin position in human HepG2 cells: although being non-random, significantly changed in daughter cells. J Struct Biol (2008) 0.93
p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development (2014) 0.92
Epigenetic regulation of epidermal differentiation. Cold Spring Harb Perspect Med (2014) 0.91
The principles of nuclear structure. Chromosome Res (2003) 0.91
The role of nuclear bodies in gene expression and disease. Biology (Basel) (2013) 0.91
Three-dimensional positioning of genes in mouse cell nuclei. Chromosoma (2008) 0.91
The radial nuclear positioning of genes correlates with features of megabase-sized chromatin domains. Chromosome Res (2012) 0.89
Single-cell genome-wide studies give new insight into nongenetic cell-to-cell variability in animals. Histochem Cell Biol (2016) 0.88
Genome size variation among and within Camellia species by using flow cytometric analysis. PLoS One (2013) 0.88
Nuclear compartmentalization of odorant receptor genes. Proc Natl Acad Sci U S A (2014) 0.87
Visualization of the spatial positioning of the SNRPN, UBE3A, and GABRB3 genes in the normal human nucleus by three-color 3D fluorescence in situ hybridization. Chromosome Res (2012) 0.86
Gene clusters, molecular evolution and disease: a speculation. Curr Genomics (2009) 0.85
Characterization of the global profile of genes expressed in cervical epithelium by Serial Analysis of Gene Expression (SAGE). BMC Genomics (2005) 0.85
Gene density and chromosome territory shape. Chromosoma (2014) 0.83
Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus. J Cell Biochem (2016) 0.82
Tissue-of-origin-specific gene repositioning in breast and prostate cancer. Histochem Cell Biol (2016) 0.82
Transcriptomic and nuclear architecture of immune cells after LPS activation. Chromosoma (2011) 0.81
Transcription-dependent spatial arrangements of CFTR and conserved adjacent loci are not conserved in human and murine nuclei. Chromosoma (2008) 0.80
Characterization of nuclear compartments identified by ectopic markers in mammalian cells with distinctly different karyotype. Chromosoma (2005) 0.79
Nuclear architecture as an epigenetic regulator of neural development and function. Neuroscience (2014) 0.79
Reorganization of the interchromosomal network during keratinocyte differentiation. Chromosoma (2015) 0.78
Specific positioning of the casein gene cluster in active nuclear domains in luminal mammary epithelial cells. Chromosome Res (2011) 0.78
Chromatin Dynamics in Lineage Commitment and Cellular Reprogramming. Genes (Basel) (2015) 0.78
Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv. PLoS One (2010) 0.77
Single-cell c-myc gene expression in relationship to nuclear domains. Chromosome Res (2008) 0.77
Large-scale probabilistic 3D organization of human chromosome territories. Hum Mol Genet (2015) 0.75
Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool. Front Genet (2016) 0.75
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data. Nucleic Acids Res (2007) 10.08
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity (2010) 6.48
A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol (2010) 6.01
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35
hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res (2008) 4.84
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell (2010) 4.34
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms. Am J Hum Genet (2008) 4.28
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med (2011) 3.82
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem (2006) 3.43
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J Pathol (2009) 3.32
microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res (2011) 3.25
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem (2009) 3.23
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq. Blood (2011) 3.00
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data. Genome Biol (2010) 2.72
Comparing CNV detection methods for SNP arrays. Brief Funct Genomic Proteomic (2009) 2.58
GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population. Bioinformatics (2008) 2.51
Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Hum Mol Genet (2012) 2.46
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data. Nucleic Acids Res (2005) 2.30
Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output. PLoS Biol (2011) 2.26
A 15q13.3 microdeletion segregating with autism. Eur J Hum Genet (2008) 2.12
Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry (2010) 2.07
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One (2010) 2.05
Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model. Brain (2013) 1.95
hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer (2010) 1.95
Quantitative high-throughput analysis of transcription factor binding specificities. Nucleic Acids Res (2004) 1.87
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
MicroRNA-10b and breast cancer metastasis. Nature (2008) 1.80
Next-generation sequencing (NGS) as a diagnostic tool for retinal degeneration reveals a much higher detection rate in early-onset disease. Eur J Hum Genet (2012) 1.80
Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels. Proc Natl Acad Sci U S A (2012) 1.79
Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions. J Cell Biol (2004) 1.74
TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology (2006) 1.73
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat Immunol (2011) 1.72
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature (2010) 1.70
Association of the KIAA0319 dyslexia susceptibility gene with reading skills in the general population. Am J Psychiatry (2008) 1.69
Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts. Circ Res (2013) 1.62
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. PLoS Genet (2011) 1.56
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol (2003) 1.54
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development. PLoS One (2009) 1.44
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet (2011) 1.43
Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development (2003) 1.42
The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Res (2010) 1.40
Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits. Genome Biol (2011) 1.40
CMIP and ATP2C2 modulate phonological short-term memory in language impairment. Am J Hum Genet (2009) 1.34
Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme. Cell Cycle (2006) 1.34
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5. Genes Dev (2008) 1.32
Refined genotype-phenotype correlations in cases of chromosome 6p deletion syndromes. Eur J Hum Genet (2004) 1.31
Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes. J Biol Chem (2006) 1.30
ROS-mediated vascular homeostatic control of root-to-shoot soil Na delivery in Arabidopsis. EMBO J (2012) 1.29
Development and evaluation of real competitive PCR for high-throughput quantitative applications. Anal Biochem (2005) 1.27
Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. Genome Res (2005) 1.25
Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA. Genome Res (2011) 1.24
CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma. Mol Cancer (2009) 1.21
Seeing clearly: the dominant and recessive nature of FOXE3 in eye developmental anomalies. Hum Mutat (2009) 1.20
The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS One (2011) 1.18
Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2. EMBO Rep (2013) 1.14
RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology. Genome Res (2011) 1.14
Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development. PLoS Genet (2012) 1.14
P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma. J Cell Sci (2007) 1.13
MAPK pathway activation and the origins of pediatric low-grade astrocytomas. J Cell Physiol (2010) 1.10
Anchoring the genome. Genome Biol (2008) 1.10
MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes. BMC Med Genomics (2009) 1.10
Microarray-based ultra-high resolution discovery of genomic deletion mutations. BMC Genomics (2014) 1.09
RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort. Acta Neuropathol (2010) 1.08
Determination of the mutation spectrum of the EXT1/EXT2 genes in British Caucasian patients with multiple osteochondromas, and exclusion of six candidate genes in EXT negative cases. Hum Mutat (2006) 1.07
Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen. Proc Natl Acad Sci U S A (2005) 1.07
Alpha-haemoglobin stabilising protein is a quantitative trait gene that modifies the phenotype of beta-thalassaemia. Br J Haematol (2006) 1.06
Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model. Ann Rheum Dis (2012) 1.06
Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis. BMC Med Genomics (2008) 1.04
Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development (2013) 1.04
Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics (2002) 1.03
Cellular interference in craniofrontonasal syndrome: males mosaic for mutations in the X-linked EFNB1 gene are more severely affected than true hemizygotes. Hum Mol Genet (2013) 1.02
The role of nuclear organization in cancer. J Pathol (2010) 1.02
Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana. Genome Res (2012) 1.01
The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci. PLoS Genet (2006) 1.01
The role of hypoxia regulated microRNAs in cancer. Curr Top Microbiol Immunol (2010) 1.00
Regenerant Arabidopsis lineages display a distinct genome-wide spectrum of mutations conferring variant phenotypes. Curr Biol (2011) 0.98
Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia. Mol Cancer (2014) 0.98
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathol (2010) 0.96
Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes. BMC Genomics (2009) 0.96
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21. Oncogene (2002) 0.95
MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation. BMC Cancer (2013) 0.95
Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast. EMBO J (2009) 0.94
Recruitment of heterogeneous nuclear ribonucleoprotein A1 in vivo to the LMP/TAP region of the major histocompatibility complex. J Biol Chem (2002) 0.92
Accuracy and reproducibility of protein-DNA microarray technology. Adv Biochem Eng Biotechnol (2007) 0.90
Suprabasal alpha 5 beta1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFbeta signaling or inducing spindle cell tumors. Mol Carcinog (2005) 0.89
Association of the aromatase gene with Alzheimer's disease in women. Neurosci Lett (2009) 0.88
BeadArray-based genotyping. Methods Mol Biol (2008) 0.88
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex. Genome Res (2008) 0.88
Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid and Notch signalling. PLoS One (2012) 0.88
Satellite DNA binding and cellular localisation of RNA helicase P68. J Cell Sci (2005) 0.87
Variations within oxygen-regulated gene expression in humans. J Appl Physiol (1985) (2008) 0.86
Antihuman epidermal growth factor receptor 2 antibody herceptin inhibits autocrine motility factor (AMF) expression and potentiates antitumor effects of AMF inhibitors. Clin Cancer Res (2002) 0.86
Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome. PLoS One (2010) 0.84
GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis. Nucleic Acids Res (2013) 0.83
Chemokine gene expression in lung CD8 T cells correlates with protective immunity in mice immunized intra-nasally with Adenovirus-85A. BMC Med Genomics (2010) 0.83
Widespread expression of BORIS/CTCFL in normal and cancer cells. PLoS One (2011) 0.83