Published in Eur J Immunol on January 01, 2002
The many roles of FAS receptor signaling in the immune system. Immunity (2009) 4.67
The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. Immunity (2010) 1.97
Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity (2008) 1.77
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner. J Immunol (2012) 1.71
FAS mRNA editing in Human Systemic Lupus Erythematosus. Hum Mutat (2011) 1.42
Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder. J Exp Med (2005) 1.40
Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. J Immunol (2010) 0.95
Immunogenetics of systemic lupus erythematosus: A comprehensive review. J Autoimmun (2015) 0.86
Somatic mutagenesis in autoimmunity. Autoimmunity (2013) 0.84
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. Eur J Hum Genet (2014) 0.84
Association of FAS and FAS ligand genes polymorphism and risk of systemic lupus erythematosus. ScientificWorldJournal (2013) 0.81
Fas-Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis. Front Immunol (2016) 0.75
Chloral Hydrate Treatment Induced Apoptosis of Macrophages via Fas Signaling Pathway. Med Sci Monit (2016) 0.75
IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature (2005) 13.23
Identification of a factor that links apoptotic cells to phagocytes. Nature (2002) 6.76
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science (2004) 6.07
Identification of Tim4 as a phosphatidylserine receptor. Nature (2007) 6.06
The many roles of FAS receptor signaling in the immune system. Immunity (2009) 4.67
IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J Immunol (2007) 4.23
Calcium-dependent phospholipid scrambling by TMEM16F. Nature (2010) 3.63
Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development. Mol Cell Biol (2004) 3.28
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol (2004) 3.18
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature (2006) 2.82
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J Exp Med (2005) 2.64
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol (2008) 2.57
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature (2005) 2.45
Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci U S A (2005) 2.38
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development (2006) 2.27
WAVE2 is required for directed cell migration and cardiovascular development. Nature (2003) 2.09
Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice. J Exp Med (2004) 2.09
Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells. Blood (2007) 2.00
Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science (2013) 1.98
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol Cell Biol (2004) 1.93
Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J Immunol (2008) 1.92
General nature of the STAT3-activated anti-inflammatory response. J Immunol (2006) 1.90
Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation. Nat Immunol (2003) 1.77
Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Mol Pharmacol (2006) 1.75
Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem (2013) 1.74
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. EMBO J (2005) 1.69
Regulation of the innate immune response by threonine-phosphatase of Eyes absent. Nature (2009) 1.69
Paranodal junction formation and spermatogenesis require sulfoglycolipids. Proc Natl Acad Sci U S A (2002) 1.68
Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. Immunity (2011) 1.59
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens. Nature (2003) 1.55
Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology (2006) 1.54
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. Proc Natl Acad Sci U S A (2010) 1.50
Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8. Proc Natl Acad Sci U S A (2005) 1.48
Expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells. J Immunol (2004) 1.47
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J Biol Chem (2004) 1.46
Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection. Proc Natl Acad Sci U S A (2013) 1.40
Imaging of Rab5 activity identifies essential regulators for phagosome maturation. Nature (2008) 1.39
Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer. Gastroenterology (2002) 1.39
Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages. J Biol Chem (2006) 1.39
Constitutive exposure of phosphatidylserine on viable cells. Proc Natl Acad Sci U S A (2011) 1.38
PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem (2005) 1.33
Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity. Nat Immunol (2003) 1.32
Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation. Genes Dev (2002) 1.29
SH2-B is required for both male and female reproduction. Mol Cell Biol (2002) 1.27
Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol (2003) 1.23
Involvement of IL-17 in Fas ligand-induced inflammation. Int Immunol (2004) 1.22
Two-step engulfment of apoptotic cells. Mol Cell Biol (2011) 1.21
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response. Cancer Res (2009) 1.19
Increased cytotoxicity of soluble Fas ligand by fusing isoleucine zipper motif. Biochem Biophys Res Commun (2004) 1.18
Mammalian twisted gastrulation is essential for skeleto-lymphogenesis. Mol Cell Biol (2003) 1.17
Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codons. Hum Mol Genet (2003) 1.16
Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice. Development (2008) 1.16
Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol (2010) 1.15
Perimembrane Aurora-A expression is a significant prognostic factor in correlation with proliferative activity in non-small-cell lung cancer (NSCLC). Ann Surg Oncol (2007) 1.15
Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly. Mol Cell Neurosci (2011) 1.15
Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer Res (2007) 1.14
Milk fat globule EGF factor 8 in the serum of human patients of systemic lupus erythematosus. J Leukoc Biol (2008) 1.13
MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure. Curr Dir Autoimmun (2006) 1.11
Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. Mech Dev (2004) 1.11
Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling. J Biol Chem (2003) 1.10
Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha. J Biol Chem (2004) 1.10
Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model. Arthritis Rheum (2010) 1.10
Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells. Eur J Immunol (2004) 1.09
H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice. Development (2010) 1.09
ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP. J Biol Chem (2005) 1.09
PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1. Int Immunol (2004) 1.09
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens. FEBS J (2007) 1.08
Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro. Cancer Res (2002) 1.07
Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4. Mol Cell Biol (2005) 1.07
Lactadherin and clearance of platelet-derived microvesicles. Blood (2008) 1.07
Phospholipase Cdelta4 is required for Ca2+ mobilization essential for acrosome reaction in sperm. J Cell Biol (2003) 1.05
Lung large cell carcinoma producing granulocyte-colony-stimulating factor. Ann Thorac Surg (2007) 1.04
Mechanism and repertoire of ASC-mediated gene expression. J Immunol (2009) 1.04
Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein. Curr Biol (2010) 1.04
Spatiotemporal activation of Rac1 for engulfment of apoptotic cells. Proc Natl Acad Sci U S A (2008) 1.03
Pathogen-associated molecular patterns sensitize macrophages to Fas ligand-induced apoptosis and IL-1 beta release. J Immunol (2003) 1.02
Phospholipase Cdelta1 is required for skin stem cell lineage commitment. EMBO J (2003) 1.02
Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia. Mol Cell Biol (2005) 1.01
Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo. Proc Natl Acad Sci U S A (2007) 1.01
Platelet apoptosis and apoptotic platelet clearance by macrophages in secondary dengue virus infections. J Infect Dis (2012) 1.01
Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med (2012) 1.00
Increased plasma levels of the soluble form of Fas ligand in patients with acute myocardial infarction and unstable angina pectoris. J Am Coll Cardiol (2002) 1.00
Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice. EMBO J (2011) 1.00
Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1. J Immunol (2003) 1.00
Nucleases in programmed cell death. Methods Enzymol (2008) 0.99
Different procarcinogenic potentials of lymphocyte subsets in a transgenic mouse model of chronic hepatitis B. Cancer Res (2004) 0.99
Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity. J Biol Chem (2011) 0.99
Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development. Mol Cell Biol (2005) 0.99
MFG-E8 in the retina and retinal pigment epithelium of rat and mouse. Mol Vis (2006) 0.98
Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cells. Cancer Immunol Immunother (2011) 0.97
Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjögren's syndrome. J Immunol (2002) 0.97
Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling. Mol Cell Biol (2003) 0.96
Absence of mechanical allodynia and Abeta-fiber sprouting after sciatic nerve injury in mice lacking membrane-type 5 matrix metalloproteinase. FEBS Lett (2004) 0.96
Co-translational folding of caspase-activated DNase with Hsp70, Hsp40, and inhibitor of caspase-activated DNase. J Biol Chem (2001) 0.96