Published in Eur J Gastroenterol Hepatol on January 01, 2002
Host Gene Polymorphisms in Relation to Helicobacter Pylori Infection and Associated Diseases in a Population Based Cohort. Gastroenterology Res (2014) 0.75
Traces of human migrations in Helicobacter pylori populations. Science (2003) 11.92
Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat Genet (2003) 4.34
Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol (2007) 4.14
BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst (2003) 3.37
The role of motility as a virulence factor in bacteria. Int J Med Microbiol (2002) 2.84
Gain and loss of multiple genes during the evolution of Helicobacter pylori. PLoS Genet (2005) 2.61
Risks of less common cancers in proven mutation carriers with lynch syndrome. J Clin Oncol (2012) 2.59
Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system. Blood (2011) 2.44
The spatial orientation of Helicobacter pylori in the gastric mucus. Proc Natl Acad Sci U S A (2004) 2.32
Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study. BMJ (2012) 2.32
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J (2011) 2.29
The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models. Nat Rev Microbiol (2010) 2.22
Helicobacter pylori genome evolution during human infection. Proc Natl Acad Sci U S A (2011) 2.15
Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions. Oncogene (2005) 2.14
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene (2005) 2.07
Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori. Mol Microbiol (2004) 1.97
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol (2009) 1.96
Microevolution of Helicobacter pylori during prolonged infection of single hosts and within families. PLoS Genet (2010) 1.89
Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity. PLoS One (2007) 1.86
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. Cancer Res (2004) 1.84
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Life Sci (2011) 1.84
Efficacy of a nationwide screening colonoscopy program for colorectal cancer. Gastroenterology (2012) 1.79
Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium. J Clin Oncol (2006) 1.70
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol (2008) 1.65
Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes. Am J Gastroenterol (2005) 1.64
A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island. PLoS Genet (2010) 1.64
Age of the association between Helicobacter pylori and man. PLoS Pathog (2012) 1.62
Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology (2010) 1.61
No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients. Eur J Hum Genet (2008) 1.58
The diversity within an expanded and redefined repertoire of phase-variable genes in Helicobacter pylori. Microbiology (2004) 1.54
STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol (2007) 1.54
Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer. Clin Gastroenterol Hepatol (2009) 1.54
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung. J Clin Endocrinol Metab (2007) 1.49
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PLoS One (2007) 1.48
Horizontal versus familial transmission of Helicobacter pylori. PLoS Pathog (2008) 1.48
Extreme phenotypic variability in a German family with X-linked myotubular myopathy associated with E404K mutation in MTM1. Neuromuscul Disord (2006) 1.46
Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study. Clin Infect Dis (2013) 1.46
A randomised phase II study of irinotecan in combination with 5-FU/FA compared with irinotecan alone as second-line treatment of patients with metastatic colorectal carcinoma. Onkologie (2007) 1.46
Evaluation of sensitivity and inter- and intra-observer variability in the detection of intestinal metaplasia and dysplasia in Barrett's esophagus with enhanced magnification endoscopy. Scand J Gastroenterol (2006) 1.45
Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart rate and blood pressure in patients with obstructive sleep apnoea. Clin Sci (Lond) (2006) 1.44
MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. Carcinogenesis (2012) 1.39
Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5. Microbes Infect (2003) 1.38
CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis. J Neuroimmunol (2006) 1.36
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine. J Exp Med (2012) 1.33
HNPCC-associated small bowel cancer: clinical and molecular characteristics. Gastroenterology (2005) 1.32
Charcot-Marie-Tooth neuropathy type 2A: novel mutations in the mitofusin 2 gene (MFN2). BMC Med Genet (2006) 1.31
NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. Neurogenetics (2004) 1.31
Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome. Mol Microbiol (2002) 1.29
The complex methylome of the human gastric pathogen Helicobacter pylori. Nucleic Acids Res (2013) 1.25
Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology (2009) 1.24
Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours. J Hepatol (2009) 1.21
Genomic changes during chronic Helicobacter pylori infection. J Bacteriol (2006) 1.20
Induction of colitis by a CD4+ T cell clone specific for a bacterial epitope. Proc Natl Acad Sci U S A (2003) 1.19
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells. Eur J Immunol (2011) 1.19
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol (2007) 1.18
Genomic evolution and transmission of Helicobacter pylori in two South African families. Proc Natl Acad Sci U S A (2013) 1.18
The neuA/flmD gene cluster of Helicobacter pylori is involved in flagellar biosynthesis and flagellin glycosylation. FEMS Microbiol Lett (2002) 1.18
Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection. J Bacteriol (2006) 1.18
Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma. Int J Cancer (2012) 1.18
Closely related Campylobacter jejuni strains from different sources reveal a generalist rather than a specialist lifestyle. BMC Genomics (2011) 1.17
Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis. Gastrointest Endosc (2010) 1.16
Mosaic DNA imports with interspersions of recipient sequence after natural transformation of Helicobacter pylori. PLoS One (2008) 1.16
Mutation and recombination in Helicobacter pylori: mechanisms and role in generating strain diversity. Int J Med Microbiol (2005) 1.15
Functional characterization and mutagenesis of the proposed behavioral sensor TlpD of Helicobacter pylori. J Bacteriol (2008) 1.13
A bisexually reproducing all-triploid vertebrate. Nat Genet (2002) 1.13
NR2A and NR2B receptor gene variations modify age at onset in Huntington disease in a sex-specific manner. Hum Genet (2007) 1.13
Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitis. PLoS One (2013) 1.12
Inhibitory effect of enterohepatic Helicobacter hepaticus on innate immune responses of mouse intestinal epithelial cells. Infect Immun (2007) 1.11
Paternity analysis of alternative male reproductive routes among the langurs (Semnopithecus entellus) of Ramnagar. Anim Behav (2001) 1.10
Naturally occurring regulatory T cells (CD4+, CD25high, FOXP3+) in the antrum and cardia are associated with higher H. pylori colonization and increased gene expression of TGF-beta1. Helicobacter (2008) 1.10
Role of the alpAB proteins and lipopolysaccharide in adhesion of Helicobacter pylori to human gastric tissue. Int J Med Microbiol (2002) 1.09
Inverse correlation of maturity and antibacterial activity in human dendritic cells. J Immunol (2005) 1.08
"Pseudodominant inheritance" of ataxia with ocular apraxia type 2 (AOA2). J Neurol (2008) 1.08
Clinical utility gene card for: Loeys-Dietz syndrome (TGFBR1/2) and related phenotypes. Eur J Hum Genet (2011) 1.07
Survival in hostile territory: the microbiota of the stomach. FEMS Microbiol Rev (2013) 1.07
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PLoS One (2010) 1.06
Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA. J Bacteriol (2010) 1.06
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer. J Pathol (2005) 1.06
Colonization of C57BL/6J and BALB/c wild-type and knockout mice with Helicobacter pylori: effect of vaccination and implications for innate and acquired immunity. Infect Immun (2003) 1.04
Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol (2009) 1.04
Impact of routine surgical ward and intensive care unit admission surveillance cultures on hospital-wide nosocomial methicillin-resistant Staphylococcus aureus infections in a university hospital: an interrupted time-series analysis. J Antimicrob Chemother (2008) 1.04
Recent progress in the genetics of Wegener's granulomatosis and Churg-Strauss syndrome. Curr Opin Rheumatol (2010) 1.03
Multilocus sequence analysis of Porphyromonas gingivalis indicates frequent recombination. Microbiology (2003) 1.02
Prevalence of familial pancreatic cancer in Germany. Int J Cancer (2004) 1.02
Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells. Oncogene (2002) 1.01
The future role of the gastroenterologist in digestive oncology: an international perspective. Gastroenterology (2011) 1.01
The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1. BMC Med Genet (2005) 1.01
Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas. J Pathol (2004) 1.01
ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease. J Mol Med (Berl) (2008) 1.01
Next-generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3-ITD or NPM1 mutations. Genes Chromosomes Cancer (2012) 1.00
Frequent loss of TIMP-3 expression in progression of esophageal and gastric adenocarcinomas. Neoplasia (2008) 1.00
Truncating mutations in Peutz-Jeghers syndrome are associated with more polyps, surgical interventions and cancers. Int J Colorectal Dis (2009) 1.00
Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution. BMC Biotechnol (2011) 1.00
Analysis of the pancreatic tumor progression by a quantitative proteomic approach and immunhistochemical validation. J Proteome Res (2009) 0.99
Paternal genetic effects on offspring fitness are context dependent within the extrapair mating system of a socially monogamous passerine. Evolution (2005) 0.99
Helicobacter pylori colonization critically depends on postprandial gastric conditions. Sci Rep (2012) 0.99
Sarcoglycanopathies: can muscle immunoanalysis predict the genotype? Neuromuscul Disord (2008) 0.98
Ethnic and geographic differentiation of Helicobacter pylori within Iran. PLoS One (2010) 0.98
Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma. Proteomics (2005) 0.98