Published in Dev Biol on October 15, 2001
Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 12.15
The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell (2009) 4.79
Identification of a unique TGF-β-dependent molecular and functional signature in microglia. Nat Neurosci (2013) 3.94
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood (2010) 3.82
The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell (2010) 3.64
The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish. BMC Dev Biol (2007) 3.44
Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death. Immunity (2008) 3.24
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci (2013) 3.11
mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish. Blood (2010) 2.82
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat Rev Neurosci (2014) 2.59
Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish. J Leukoc Biol (2010) 2.08
Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits. PLoS One (2011) 1.92
The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations. Toxicol Pathol (2003) 1.79
Zebrafish in hematology: sushi or science? Blood (2008) 1.69
Host-pathogen interactions made transparent with the zebrafish model. Curr Drug Targets (2011) 1.60
Origin and differentiation of microglia. Front Cell Neurosci (2013) 1.58
Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host Microbe (2015) 1.47
Basonuclin-2 requirements for zebrafish adult pigment pattern development and female fertility. PLoS Genet (2009) 1.39
Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation. PLoS Pathog (2017) 1.38
Characterization of zebrafish larval inflammatory macrophages. Dev Comp Immunol (2009) 1.37
Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice. J Neuroinflammation (2012) 1.36
MyD88 innate immune function in a zebrafish embryo infection model. Infect Immun (2006) 1.35
Mucosal immunoglobulins and B cells of teleost fish. Dev Comp Immunol (2011) 1.28
Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell (2014) 1.27
Burkholderia cenocepacia creates an intramacrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection. Infect Immun (2010) 1.25
The cellular response in neuroinflammation: The role of leukocytes, microglia and astrocytes in neuronal death and survival. Clin Neurosci Res (2006) 1.24
Regulation of macrophage development and function in peripheral tissues. Nat Rev Immunol (2015) 1.16
Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda. BMC Immunol (2011) 1.12
Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells. Blood Cells Mol Dis (2013) 1.11
Identification of the molecular signatures integral to regenerating photoreceptors in the retina of the zebra fish. J Ocul Biol Dis Infor (2008) 1.10
The brain's best friend: microglial neurotoxicity revisited. Front Cell Neurosci (2013) 1.09
Fate mapping embryonic blood in zebrafish: multi- and unipotential lineages are segregated at gastrulation. Dev Cell (2009) 1.09
NADPH oxidase-driven phagocyte recruitment controls Candida albicans filamentous growth and prevents mortality. PLoS Pathog (2013) 1.06
Leptospira interrogans stably infects zebrafish embryos, altering phagocyte behavior and homing to specific tissues. PLoS Negl Trop Dis (2009) 1.04
Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model. Dis Model Mech (2014) 1.02
Apoptotic cells are cleared by directional migration and elmo1- dependent macrophage engulfment. Curr Biol (2012) 0.99
Plastin family of actin-bundling proteins: its functions in leukocytes, neurons, intestines, and cancer. Int J Cell Biol (2012) 0.96
The visual system of zebrafish and its use to model human ocular diseases. Dev Neurobiol (2012) 0.96
Muscle degeneration and leukocyte infiltration caused by mutation of zebrafish Fad24. Dev Dyn (2009) 0.96
An anti-inflammatory NOD-like receptor is required for microglia development. Cell Rep (2013) 0.95
Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafish. BMC Dev Biol (2010) 0.95
The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.95
Ischemia is not required for arteriogenesis in zebrafish embryos. Arterioscler Thromb Vasc Biol (2007) 0.94
The role of microglia in the neurogenesis of zebrafish retina. Biochem Biophys Res Commun (2012) 0.92
Drosophila as a model for the two myeloid blood cell systems in vertebrates. Exp Hematol (2014) 0.92
Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood (2012) 0.90
Glial cell development and function in zebrafish. Cold Spring Harb Perspect Biol (2014) 0.90
Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation. Dis Model Mech (2014) 0.89
Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish. PLoS One (2015) 0.88
Macrophages and cellular immunity in Drosophila melanogaster. Semin Immunol (2016) 0.87
Characterization of mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter. Proc Natl Acad Sci U S A (2010) 0.86
Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake. Dis Model Mech (2015) 0.86
Targeting innate immunity for neurodegenerative disorders of the central nervous system. J Neurochem (2016) 0.85
Generating parabiotic zebrafish embryos for cell migration and homing studies. Nat Methods (2013) 0.85
Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish. Cell Microbiol (2015) 0.83
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity. Cell Microbiol (2013) 0.81
The Rag-Ragulator Complex Regulates Lysosome Function and Phagocytic Flux in Microglia. Cell Rep (2016) 0.81
Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum. Dis Model Mech (2014) 0.81
Zebrafish kidney phagocytes utilize macropinocytosis and Ca+-dependent endocytic mechanisms. PLoS One (2009) 0.80
Embryonic Medaka Model of Microglia in the Developing CNS Allowing In Vivo Analysis of Their Spatiotemporal Recruitment in Response to Irradiation. PLoS One (2015) 0.79
In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord. Front Cell Neurosci (2015) 0.79
The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish. PLoS One (2015) 0.79
Perspectives on antigen presenting cells in zebrafish. Dev Comp Immunol (2014) 0.79
Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish. J Hematol Oncol (2014) 0.78
Developmental changes in microglial mobilization are independent of apoptosis in the neonatal mouse hippocampus. Brain Behav Immun (2015) 0.78
Role of microglia in embryonic neurogenesis. Exp Biol Med (Maywood) (2016) 0.77
Abnormal retinal development in Cloche mutant zebrafish. Dev Dyn (2015) 0.77
Zebrafish as a model for leukemia and other hematopoietic disorders. J Hematol Oncol (2015) 0.77
The phosphate exporter xpr1b is required for differentiation of tissue-resident macrophages. Cell Rep (2014) 0.77
Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites. PLoS One (2013) 0.77
Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors. Blood (2016) 0.77
Intravitreous delivery of the corticosteroid fluocinolone acetonide attenuates retinal degeneration in S334ter-4 rats. Invest Ophthalmol Vis Sci (2010) 0.77
Animal models of tuberculosis: zebrafish. Cold Spring Harb Perspect Med (2014) 0.77
Correction: The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.77
Neuronal and microglial regulators of cortical wiring: usual and novel guideposts. Front Neurosci (2015) 0.77
Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord. Glia (2016) 0.76
Neurocytotoxic effects of iron-ions on the developing brain measured in vivo using medaka (Oryzias latipes), a vertebrate model. Int J Radiat Biol (2011) 0.76
Vertebrate epidermal cells are broad-specificity phagocytes that clear sensory axon debris. J Neurosci (2015) 0.76
Transcriptome Analysis of Chemically-Induced Sensory Neuron Ablation in Zebrafish. PLoS One (2016) 0.76
Peripheral glia have a pivotal role in the initial response to axon degeneration of peripheral sensory neurons in zebrafish. PLoS One (2014) 0.76
Granulin knock out zebrafish lack frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology. PLoS One (2015) 0.76
Antigen Uptake during Different Life Stages of Zebrafish (Danio rerio) Using a GFP-Tagged Yersinia ruckeri. PLoS One (2016) 0.76
Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response. J Neuroinflammation (2017) 0.75
The Indispensable Roles of Microglia and Astrocytes during Brain Development. Front Hum Neurosci (2016) 0.75
c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish. Leukemia (2016) 0.75
Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish. Glia (2016) 0.75
Zebrafish endzone regulates neural crest-derived chromatophore differentiation and morphology. PLoS One (2008) 0.75
Danio rerio: the Janus of the bone from embryo to scale. Clin Cases Miner Bone Metab (2015) 0.75
Non-mammalian model systems for studying neuro-immune interactions after spinal cord injury. Exp Neurol (2014) 0.75
Regulation of Drosophila hematopoietic sites by Activin-β from active sensory neurons. Nat Commun (2017) 0.75
Macrophage physiology in the eye. Pflugers Arch (2017) 0.75
Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (2017) 0.75
Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages. Immunity (2017) 0.75
Progranulin regulates neurogenesis in the developing vertebrate retina. Dev Neurobiol (2017) 0.75
Abscopal Activation of Microglia in Embryonic Fish Brain Following Targeted Irradiation with Heavy-Ion Microbeam. Int J Mol Sci (2017) 0.75
The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS. Front Mol Neurosci (2017) 0.75
Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos. Development (1993) 5.81
Ontogeny and behaviour of early macrophages in the zebrafish embryo. Development (1999) 4.01
A zebrafish nanos-related gene is essential for the development of primordial germ cells. Genes Dev (2001) 2.67
Roles for Fgf signaling during zebrafish fin regeneration. Dev Biol (2000) 2.36
Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product. Cell (1991) 2.21
The twist gene: isolation of a Drosophila zygotic gene necessary for the establishment of dorsoventral pattern. Nucleic Acids Res (1987) 2.07
Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development (1999) 1.85
Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. Development (2000) 1.74
sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. Development (2001) 1.64
casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish. Genes Dev (2001) 1.61
The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev Biol (1991) 1.60
Evolutionary origins of vertebrate appendicular muscle. Nature (2000) 1.52
Pattern formation in the lateral line of zebrafish. Mech Dev (2001) 1.44
A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula. Development (1997) 1.34
Expression of snail2, a second member of the zebrafish snail family, in cephalic mesendoderm and presumptive neural crest of wild-type and spadetail mutant embryos. Dev Biol (1995) 1.34
Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo. Dev Biol (1999) 1.26
Goosecoid expression in neurectoderm and mesendoderm is disrupted in zebrafish cyclops gastrulas. Dev Biol (1994) 1.24
Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature (2000) 1.15
Both apolipoprotein E and A-I genes are present in a nonmammalian vertebrate and are highly expressed during embryonic development. Proc Natl Acad Sci U S A (1997) 1.10
An inherited functional circadian clock in zebrafish embryos. Science (2000) 1.09
Cell-autonomous shift from axial to paraxial mesodermal development in zebrafish floating head mutants. Development (1995) 1.07
D4 Dopamine receptor genes of zebrafish and effects of the antipsychotic clozapine on larval swimming behaviour. Genes Brain Behav (2007) 1.06
Anteroposterior patterning is required within segments for somite boundary formation in developing zebrafish. Development (2000) 1.05
Genetic interactions in zebrafish midline development. Dev Biol (1997) 1.03
The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos. Dev Biol (1996) 0.98
spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development (2001) 0.98
Zebrafish evx1 is dynamically expressed during embryogenesis in subsets of interneurones, posterior gut and urogenital system. Mech Dev (2000) 0.97
The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus. Development (2000) 0.95
Novel FGF receptor (Z-FGFR4) is dynamically expressed in mesoderm and neurectoderm during early zebrafish embryogenesis. Dev Dyn (1995) 0.95
Maternal and zygotic activity of the zebrafish ogon locus antagonizes BMP signaling. Dev Biol (1999) 0.95
Morpholino knock-down of antivin1 and antivin2 upregulates nodal signaling. Genesis (2001) 0.85
Dorsoventral development of the Drosophila embryo is controlled by a cascade of transcriptional regulators. Dev Suppl (1992) 0.81
The Mdm2 gene of zebrafish (Danio rerio): preferential expression during development of neural and muscular tissues, and absence of tumor formation after overexpression of its cDNA during early embryogenesis. Differentiation (2000) 0.80
Asymmetric expression of antivin/lefty1 in the early chick embryo. Mech Dev (2000) 0.79
Sequence and expression pattern of ziro7, a novel, divergent zebrafish iroquois homeobox gene. Mech Dev (2001) 0.78
Calsenilin is required for endocrine pancreas development in zebrafish. Dev Dyn (2007) 0.78