Mitsuhiko Osaki

Author PubWeight™ 57.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 2009 2.92
2 IFATS collection: in vivo therapeutic potential of human adipose tissue mesenchymal stem cells after transplantation into mice with liver injury. Stem Cells 2008 1.75
3 Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther 2009 1.74
4 Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure. J Gastroenterol Hepatol 2008 1.68
5 The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle 2007 1.45
6 High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas. Oral Oncol 2008 1.29
7 SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells 2010 1.19
8 Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS One 2011 1.13
9 Minichromosome maintenance protein 7 in colorectal cancer: implication of prognostic significance. Int J Oncol 2008 1.12
10 Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines. Pancreas 2004 1.11
11 Proteomic identification of differentially-expressed genes in human gastric carcinomas. Proteomics 2005 1.07
12 Expression of Fas and Fas ligand in esophageal tissue mucosa and carcinomas. Int J Oncol 2002 1.07
13 Serum miR-210 as a potential biomarker of early clear cell renal cell carcinoma. Int J Oncol 2013 1.07
14 Prostatic stromal sarcoma: case report and review of the literature. Pathol Int 2003 1.05
15 Aberrant expression of selenoproteins in the progression of colorectal cancer. Cancer Lett 2007 1.05
16 Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation. Lab Invest 2002 1.04
17 Cyclo-oxygenase-1 and -2 expression in human oral mucosa, dysplasias and squamous cell carcinomas and their pathological significance. Oral Oncol 2005 1.02
18 Identification of PITX1 as a TERT suppressor gene located on human chromosome 5. Mol Cell Biol 2011 1.01
19 Evaluation of the antiangiogenic effect of Taxol in a human epithelial ovarian carcinoma cell line. Cancer Chemother Pharmacol 2003 0.98
20 SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest. Cell Cycle 2009 0.97
21 Expression of RUNX3 protein in human lung adenocarcinoma: implications for tumor progression and prognosis. Cancer Sci 2005 0.97
22 CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. Int J Oncol 2006 0.97
23 Immunolocalisation of E-cadherin and beta-catenin in human pterygium. Br J Ophthalmol 2007 0.96
24 Epstein-Barr virus-infected malignant T/NK-cell lymphoma in a patient with hypersensitivity to mosquito bites. Int J Surg Pathol 2004 0.95
25 The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease. Arthritis Rheum 2008 0.95
26 CYR61 downregulation correlates with tumor progression by promoting MMP-7 expression in human gastric carcinoma. Oncology 2008 0.92
27 Expression of hypoxia-inducible factor (HIF-1alpha), VEGF-C and VEGF-D in non-invasive and invasive breast ductal carcinomas. Anticancer Res 2005 0.92
28 Carp, a cardiac ankyrin-repeated protein, and its new homologue, Arpp, are differentially expressed in heart, skeletal muscle, and rhabdomyosarcomas. Am J Pathol 2002 0.92
29 MCM2 and Ki-67 expression in human lung adenocarcinoma: prognostic implications. Pathobiology 2004 0.91
30 Expression of cyclo-oxygenase-2 is correlated with high intratumoral microvessel density and low apoptotic index in human esophageal squamous cell carcinomas. Virchows Arch 2002 0.90
31 Minichromosome maintenance 2 expression is correlated with mode of invasion and prognosis in oral squamous cell carcinomas. J Oral Pathol Med 2003 0.89
32 Searching for genes involved in arteriosclerosis: proteomic analysis of cultured human umbilical vein endothelial cells undergoing replicative senescence. Cell Struct Funct 2003 0.88
33 COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines. DNA Cell Biol 2005 0.87
34 Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1. Cancer Sci 2007 0.86
35 Expression of erythropoietin receptor in human Merkel cell carcinoma of the eyelid. Anticancer Res 2007 0.86
36 Increased expression of erythropoietin receptor in human pterygial tissues. Int J Mol Med 2007 0.86
37 Expression of RUNX3 protein in human esophageal mucosa and squamous cell carcinoma. Pathobiology 2005 0.83
38 Expression of minichromosome maintenance-2 in human malignant fibrous histiocytomas: Correlations with Ki-67 and P53 expression, and apoptosis. Int J Mol Med 2002 0.82
39 A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells. Biochem Biophys Res Commun 2011 0.82
40 Altered expression of cardiac ankyrin repeat protein and its homologue, ankyrin repeat protein with PEST and proline-rich region, in atrophic muscles in amyotrophic lateral sclerosis. Pathobiology 2003 0.82
41 Tubular adenoma and intramucosal intestinal-type adenocarcinoma of the stomach: what are the pathobiological differences? Gastric Cancer 2003 0.82
42 High expression of enhancer of zeste homologue 2 indicates poor prognosis in patients with soft tissue sarcomas. Mol Med Rep 2011 0.82
43 A selective cyclooxygenase-2 inhibitor, NS-398, inhibits cell growth by cell cycle arrest in a human malignant fibrous histiocytoma cell line. Anticancer Res 2004 0.81
44 Cytochrome P450 aromatase gene (CYP19) expression in gastric cancer. Gastric Cancer 2008 0.81
45 Co-expression of Cox-2 and EGFR in stage I human bronchial adenocarcinomas. Lung Cancer 2004 0.80
46 Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. Skeletal Radiol 2013 0.80
47 Establishment and characterization of a transgenic mouse model for in vivo imaging of Bmp4 expression in the pancreas. PLoS One 2011 0.80
48 Cyclooxygenase-2 expression in human gastric tubular adenomas and carcinomas; correlation with intratumoral microvessel density and apoptotic index. Anticancer Res 2004 0.78
49 Induction of thymidine phosphorylase expression by Taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line. Anticancer Res 2003 0.78
50 Chronic inflammation-derived nitric oxide causes conversion of human colonic adenoma cells into adenocarcinoma cells. Exp Cell Res 2013 0.77
51 Prognostic significance of sirtuin 2 protein nuclear localization in glioma: an immunohistochemical study. Oncol Rep 2012 0.77
52 Immunohistochemical analysis of a muscle ankyrin-repeat protein, Arpp, in paraffin-embedded tumors: evaluation of Arpp as a tumor marker for rhabdomyosarcoma. Hum Pathol 2005 0.77
53 Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis. Proteomics 2014 0.77
54 Runt-related transcription factor 3 expression in human oral squamous cell carcinomas; implication for tumor progression and prognosis. Oral Oncol 2006 0.77
55 Expression of cyclooxygenase-1 and cyclooxygenase-2 in human esophageal mucosa, dysplasia and carcinoma. Pathobiology 2004 0.77
56 Identification of the control region of pancreatic expression of Bmp4 in vitro and in vivo. PLoS One 2013 0.76
57 Induction of efficient apoptosis and cell-cycle arrest in tumor cells by adenovirus-mediated p53 A4 mutant. Pathol Int 2006 0.76
58 Cyclooxygenase-2 in human malignant fibrous histiocytoma: correlations with intratumoral microvessel density, expression of vascular endothelial growth factor and thymidine phosphorylase. Int J Mol Med 2004 0.76
59 COX-2 correlates with F-box protein, Skp2 expression and prognosis in human gastric carcinoma. Int J Oncol 2005 0.76
60 Anti-Fas antibody-induced apoptosis and its signal transduction in human gastric carcinoma cell lines. Int J Oncol 2003 0.75
61 Down-regulation of cobalt-induced HIF-1alpha expression correlates with cell proliferation and apoptosis in human gastric carcinoma cells. Oncol Rep 2008 0.75
62 Induction of thymidine phosphorylase expression and enhancement of Furtulon sensitivity by Taxol in a human ovarian carcinoma cell line. Anticancer Res 2003 0.75
63 Expression of thymidine phosphorylase in choroidal malignant melanoma associated with neovascular glaucoma. Pathol Int 2005 0.75