Joachim Clos

Author PubWeight™ 27.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages. J Cell Sci 2010 1.67
2 Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection. J Biol Chem 2003 1.42
3 Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells. J Immunol 2010 1.32
4 Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism. Arch Biochem Biophys 2002 1.11
5 Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage. Proc Natl Acad Sci U S A 2010 1.08
6 Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus. Mol Biochem Parasitol 2008 1.03
7 Identification of a Leishmania infantum gene mediating resistance to miltefosine and SbIII. Int J Parasitol 2008 1.02
8 Inhibition of HSP90 in Trypanosoma cruzi induces a stress response but no stage differentiation. Eukaryot Cell 2002 0.96
9 Secreted virulence factors and immune evasion in visceral leishmaniasis. J Leukoc Biol 2012 0.94
10 Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani. Proteomics 2003 0.93
11 Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro. J Struct Biol 2006 0.92
12 Characterization of a subunit of the outer dynein arm docking complex necessary for correct flagellar assembly in Leishmania donovani. PLoS Negl Trop Dis 2010 0.87
13 A Leishmania donovani gene that confers accelerated recovery from stationary phase growth arrest. Int J Parasitol 2004 0.85
14 Leishmania major: identification of developmentally regulated proteins in procyclic and metacyclic promastigotes. Exp Parasitol 2008 0.84
15 Rapid identification of Leishmania spp. in formalin-fixed, paraffin-embedded tissue samples by fluorescence in situ hybridization. Trop Med Int Health 2012 0.83
16 The co-chaperone SGT of Leishmania donovani is essential for the parasite's viability. Cell Stress Chaperones 2009 0.82
17 Complement C3 is required for the progression of cutaneous lesions and neutrophil attraction in Leishmania major infection. Med Microbiol Immunol 2004 0.82
18 Spontaneous recovery of pathogenicity by Leishmania major hsp100-/- alters the immune response in mice. Infect Immun 2006 0.82
19 One-step generation of double-allele gene replacement mutants in Leishmania donovani. Int J Parasitol 2008 0.81
20 LmxMPK4, an essential mitogen-activated protein kinase of Leishmania mexicana is phosphorylated and activated by the STE7-like protein kinase LmxMKK5. Int J Parasitol 2010 0.80
21 Leishmania donovani HslV does not interact stably with HslU proteins. Int J Parasitol 2012 0.79
22 Comparative analysis of the human and chicken prion protein copper binding regions at pH 6.5. J Biol Chem 2005 0.79
23 The Hsp90-Sti1 interaction is critical for Leishmania donovani proliferation in both life cycle stages. Cell Microbiol 2012 0.79
24 The loss of virulence of histone H1 overexpressing Leishmania donovani parasites is directly associated with a reduction of HSP83 rate of translation. Mol Microbiol 2013 0.78
25 Oligomerization of the proteolytic products is an intrinsic property of prion proteins. Biochem Biophys Res Commun 2004 0.78
26 The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status. Mol Microbiol 2014 0.78
27 Overexpression of a single Leishmania major gene enhances parasite infectivity in vivo and in vitro. Mol Microbiol 2010 0.77
28 Stage-specific expression of the mitochondrial co-chaperonin of Leishmania donovani, CPN10. Kinetoplastid Biol Dis 2005 0.77
29 Reduced antimony accumulation in ARM58-overexpressing Leishmania infantum. Antimicrob Agents Chemother 2013 0.77
30 Leishmania donovani P23 protects parasites against HSP90 inhibitor-mediated growth arrest. Cell Stress Chaperones 2015 0.75
31 Synthetic human prion protein octapeptide repeat binds to the proteinase K active site. Biochem Biophys Res Commun 2004 0.75