Published in JAMA on January 18, 2002
Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: the TACT randomized trial. JAMA (2013) 5.31
Design of the Trial to Assess Chelation Therapy (TACT). Am Heart J (2012) 2.09
Chelation in metal intoxication. Int J Environ Res Public Health (2010) 1.51
Oxidative genome damage and its repair in neurodegenerative diseases: function of transition metals as a double-edged sword. J Alzheimers Dis (2011) 1.13
Calcium orthophosphates: occurrence, properties, biomineralization, pathological calcification and biomimetic applications. Biomatter (2013) 0.94
Challenges associated with metal chelation therapy in Alzheimer's disease. J Alzheimers Dis (2009) 0.93
Why the NIH Trial to Assess Chelation Therapy (TACT) should be abandoned. Medscape J Med (2008) 0.90
EDTA chelation therapy for cardiovascular disease: a systematic review. BMC Cardiovasc Disord (2005) 0.87
Heavy Metals, Cardiovascular Disease, and the Unexpected Benefits of Chelation Therapy. J Am Coll Cardiol (2016) 0.82
Calcium orthophosphates (CaPO4): occurrence and properties. Prog Biomater (2015) 0.78
Opinions on chelation therapy in patients undergoing coronary angiography: cross-sectional survey. Can J Cardiol (2007) 0.77
Chelation therapy after the trial to assess chelation therapy: results of a unique trial. Curr Opin Cardiol (2014) 0.76
Chelation therapy and cardiovascular disease: connecting scientific silos to benefit cardiac patients. Trends Cardiovasc Med (2014) 0.76
Synthesis and Crystal Structure of the Bioinorganic Complex [Sb(Hedta)]·2H2O. Bioinorg Chem Appl (2014) 0.75
Does chelation therapy work for ischemic heart disease? Can Fam Physician (2003) 0.75
Chelation therapy for patients with ischemic heart disease. JAMA (2002) 0.75
Chelation therapy for patients with ischemic heart disease. JAMA (2002) 0.75
Chelation therapy to treat atherosclerosis, particularly in diabetes: is it time to reconsider? Expert Rev Cardiovasc Ther (2016) 0.75
Rhythm control versus rate control for atrial fibrillation and heart failure. N Engl J Med (2008) 6.17
D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. Ann Intern Med (2004) 6.15
A randomized trial of a single dose of oral dexamethasone for mild croup. N Engl J Med (2004) 5.02
Epinephrine and dexamethasone in children with bronchiolitis. N Engl J Med (2009) 4.35
Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation (2004) 4.04
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Survival after coronary revascularization in the elderly. Circulation (2002) 3.17
Characteristics and outcomes of patients with acute myocardial infarction and angiographically normal coronary arteries. Am J Cardiol (2005) 2.69
The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk: the TRENDS study. Circ Arrhythm Electrophysiol (2009) 2.59
Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy. Kidney Int (2008) 2.46
Cardiovascular outcomes in the AFFIRM Trial (Atrial Fibrillation Follow-Up Investigation of Rhythm Management). An assessment of individual antiarrhythmic drug therapies compared with rate control with propensity score-matched analyses. J Am Coll Cardiol (2011) 2.42
Cardiac rehabilitation attendance and outcomes in coronary artery disease patients. Circulation (2012) 2.30
Increases in antihypertensive prescriptions and reductions in cardiovascular events in Canada. Hypertension (2008) 2.23
Effect of chorioamnionitis on brain development and injury in premature newborns. Ann Neurol (2009) 2.18
The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trends. Hypertension (2005) 2.15
A decision rule for diagnostic testing in obstructive sleep apnea. Am J Respir Crit Care Med (2003) 2.14
Current perspectives on coronary chronic total occlusions: the Canadian Multicenter Chronic Total Occlusions Registry. J Am Coll Cardiol (2012) 2.11
Sex differences in access to coronary revascularization after cardiac catheterization: importance of detailed clinical data. Ann Intern Med (2002) 2.03
The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part II - therapy. Can J Cardiol (2005) 2.03
Procedural pain and brain development in premature newborns. Ann Neurol (2012) 1.91
Validation of a new simple scale to measure symptoms in atrial fibrillation: the Canadian Cardiovascular Society Severity in Atrial Fibrillation scale. Circ Arrhythm Electrophysiol (2009) 1.87
The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2012) 1.86
The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol (2013) 1.85
Incidence of newly detected atrial arrhythmias via implantable devices in patients with a history of thromboembolic events. Stroke (2009) 1.81
Sex differences in outcomes after cardiac catheterization: effect modification by treatment strategy and time. JAMA (2004) 1.79
Functional status in rate- versus rhythm-control strategies for atrial fibrillation: results of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Functional Status Substudy. J Am Coll Cardiol (2005) 1.77
Temporal trends in antihypertensive drug prescriptions in Canada before and after introduction of the Canadian Hypertension Education Program. J Hypertens (2003) 1.76
Abnormal brain maturation in preterm neonates associated with adverse developmental outcomes. Neurology (2013) 1.73
Development and validation of a surname list to define Chinese ethnicity. Med Care (2006) 1.71
Temporal relationship of atrial tachyarrhythmias, cerebrovascular events, and systemic emboli based on stored device data: a subgroup analysis of TRENDS. Heart Rhythm (2011) 1.71
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy. Can J Cardiol (2006) 1.67
Quality of life after coronary revascularization in the elderly. Eur Heart J (2006) 1.66
Multiple imputation versus data enhancement for dealing with missing data in observational health care outcome analyses. J Clin Epidemiol (2002) 1.65
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1--blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2009) 1.64
Population rates of cardiac catheterization and yield of high-risk coronary artery disease. CMAJ (2005) 1.64
Brain injury and development in newborns with critical congenital heart disease. Neurology (2013) 1.61
Analysis of implantable cardioverter defibrillator therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial. J Cardiovasc Electrophysiol (2003) 1.59
Relation of ejection fraction and inducible ventricular tachycardia to mode of death in patients with coronary artery disease: an analysis of patients enrolled in the multicenter unsustained tachycardia trial. Circulation (2002) 1.58
Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation (2011) 1.58
Kaplan-Meier methods yielded misleading results in competing risk scenarios. J Clin Epidemiol (2006) 1.58
Skin conductance fluctuations correlate poorly with postoperative self-report pain measures in school-aged children. Anesthesiology (2010) 1.55
Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol (2010) 1.55
Women with coronary artery disease report worse health-related quality of life outcomes compared to men. Health Qual Life Outcomes (2004) 1.53
Cost-effectiveness of rhythm versus rate control in atrial fibrillation. Ann Intern Med (2004) 1.52
Parents' perceptions of research with newborns. J Perinatol (2002) 1.52
Accuracy of city postal code coordinates as a proxy for location of residence. Int J Health Geogr (2004) 1.52
Vernakalant hydrochloride for rapid conversion of atrial fibrillation: a phase 3, randomized, placebo-controlled trial. Circulation (2008) 1.51
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2007) 1.49
The 2001 Canadian recommendations for the management of hypertension: Part two--Therapy. Can J Cardiol (2002) 1.49
The frequency of complications associated with the use of multiple-dose activated charcoal. Ann Emerg Med (2003) 1.47
Renal outcomes associated with invasive versus conservative management of acute coronary syndrome: propensity matched cohort study. BMJ (2013) 1.46
Beneficial effects of statin therapy for prevention of atrial fibrillation following DDDR pacemaker implantation. Eur Heart J (2008) 1.44
Association of postoperative complications with hospital costs and length of stay in a tertiary care center. J Gen Intern Med (2006) 1.42
The Euro Heart Survey on atrial fibrillation: a picture and a thousand words. Eur Heart J (2005) 1.42
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part I--Blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2006) 1.42
Brain death: resolving inconsistencies in the ethical declaration of death. Can J Anaesth (2003) 1.41
Relationship between initial treatment strategy and quality of life in patients with coronary chronic total occlusions. EuroIntervention (2014) 1.41
Randomized controlled trial of fixed rate versus rate responsive pacing after radiofrequency atrioventricular junction ablation: quality of life, ventricular refractoriness, and paced QT dispersion. J Cardiovasc Electrophysiol (2003) 1.39
The Western Canada Waiting List Project: development of a priority referral score for hip and knee arthroplasty. J Eval Clin Pract (2007) 1.39
The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2011) 1.38
Slower postnatal growth is associated with delayed cerebral cortical maturation in preterm newborns. Sci Transl Med (2013) 1.36
Economic evaluation of sirolimus-eluting stents. CMAJ (2005) 1.32
Do educational materials change knowledge and behaviour about crying and shaken baby syndrome? A randomized controlled trial. CMAJ (2009) 1.31
Remotely controlled mandibular protrusion during sleep predicts therapeutic success with oral appliances in patients with obstructive sleep apnea. Sleep (2013) 1.27
The impact of the Canadian Hypertension Education Programme in its first decade. Eur Heart J (2009) 1.26
Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis. Am J Med (2005) 1.20
Diagnostic cardiac catheterization and revascularization rates for coronary heart disease. Can J Cardiol (2004) 1.19
Attitudes of the new generation of Canadian obstetricians: how do they differ from their predecessors? Birth (2011) 1.19
Mucoid and nonmucoid Burkholderia cepacia complex bacteria in cystic fibrosis infections. Am J Respir Crit Care Med (2010) 1.18
Postnatal infection is associated with widespread abnormalities of brain development in premature newborns. Pediatr Res (2012) 1.18
Revascularization in patients with heart failure. CMAJ (2006) 1.18
Ordinal regression model and the linear regression model were superior to the logistic regression models. J Clin Epidemiol (2006) 1.17
Smoking cessation initiated during hospital stay for patients with coronary artery disease: a randomized controlled trial. CMAJ (2009) 1.16
Treating the right patient at the right time: an innovative approach to the management of atrial fibrillation. Can J Cardiol (2008) 1.16
A novel, simple scale for assessing the symptom severity of atrial fibrillation at the bedside: the CCS-SAF scale. Can J Cardiol (2006) 1.15
Differences in admission rates of children with bronchiolitis by pediatric and general emergency departments. Pediatrics (2002) 1.15
Long-term silicone central venous catheters impregnated with minocycline and rifampin decrease rates of catheter-related bloodstream infection in cancer patients: a prospective randomized clinical trial. J Clin Oncol (2004) 1.13
Improved suppression of recurrent atrial fibrillation with dual-site right atrial pacing and antiarrhythmic drug therapy. J Am Coll Cardiol (2002) 1.13
Hepatocellular carcinoma incidence trends in Canada: analysis by birth cohort and period of diagnosis. Liver Int (2008) 1.13
Does intensity of rate-control influence outcome in atrial fibrillation? An analysis of pooled data from the RACE and AFFIRM studies. Europace (2006) 1.09
The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part I - blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2010) 1.07
A cluster randomized controlled trial comparing three methods of disseminating practice guidelines for children with croup [ISRCTN73394937]. Implement Sci (2006) 1.06
Minimal clinically important difference for 7 measures of fatigue in patients with systemic lupus erythematosus. J Rheumatol (2008) 1.05
The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2008) 1.05
Usefulness of vernakalant hydrochloride injection for rapid conversion of atrial fibrillation. Am J Cardiol (2010) 1.03
Evaluation of satisfaction with midwifery care. Midwifery (2002) 1.03
The 2001 Canadian recommendations for the management of hypertension: Part one--Assessment for diagnosis, cardiovascular risk, causes and lifestyle modification. Can J Cardiol (2002) 1.02
Prophylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysis. Ann Thorac Surg (2006) 1.02
A novel imaging technique to measure capillary-refill time: improving diagnostic accuracy for dehydration in young children with gastroenteritis. Pediatrics (2006) 1.02
Score for neonatal acute physiology-II and neonatal pain predict corticospinal tract development in premature newborns. Pediatr Neurol (2013) 1.01
Identification by families of pediatric adverse events and near misses overlooked by health care providers. CMAJ (2011) 1.01
Extreme premature birth is not associated with impaired development of brain microstructure. J Pediatr (2010) 1.00
Misclassification of income quintiles derived from area-based measures. A comparison of enumeration area and forward sortation area. Can J Public Health (2002) 0.99