PGP9.5 as a marker for invasive colorectal cancer.

Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1. Proc Natl Acad Sci U S A (2006) 1.74

Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease. Proc Natl Acad Sci U S A (2009) 1.28

Analysis of the human pancreatic stellate cell secreted proteome. Pancreas (2011) 1.16

The role of PGP9.5 as a tumor suppressor gene in human cancer. Int J Cancer (2008) 1.03

Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells. Exp Mol Med (2009) 1.03

Deubiquitinases and the new therapeutic opportunities offered to cancer. Endocr Relat Cancer (2015) 1.02

Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc Natl Acad Sci U S A (2010) 1.01

Over-expression of ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells. Int J Oncol (2008) 0.95

CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer. Br J Cancer (2004) 0.93

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α. Nat Commun (2015) 0.92

Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma. J Transl Med (2009) 0.91

Plasminogen activator inhibitor-1 as a potential marker for the malignancy of colorectal cancer. Br J Cancer (2005) 0.89

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation. Mol Cancer (2011) 0.88

Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity. J Biol Chem (2013) 0.87

DNA promoter methylation as a diagnostic and therapeutic biomarker in gallbladder cancer. Clin Epigenetics (2012) 0.87

Cellular responses to ErbB-2 overexpression in human mammary luminal epithelial cells: comparison of mRNA and protein expression. Br J Cancer (2004) 0.84

Localization of nerve fibers in colonic polyps, adenomas, and adenocarcinomas by immunocytochemical staining for PGP 9.5. Dig Dis Sci (2011) 0.83

Potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 does not predict patient survival in non-small cell lung carcinoma. J Exp Clin Cancer Res (2011) 0.81

Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients. J Cancer Res Clin Oncol (2013) 0.80

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction. Biochem J (2016) 0.79

The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorg Med Chem Lett (2012) 0.78

The stromal genome heterogeneity between breast and prostate tumors revealed by a comparative transcriptomic analysis. Oncotarget (2015) 0.78

Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1. Sci Rep (2012) 0.77

Ubiquitin carboxy-terminal hydrolase L1 may be involved in the development of mammary phyllodes tumors. Virchows Arch (2013) 0.76

UCH-L1 involved in regulating the degradation of EGFR and promoting malignant properties in drug-resistant breast cancer. Int J Clin Exp Pathol (2015) 0.75

Molecular Characteristics of Large Parathyroid Adenomas. World J Surg (2016) 0.75

Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer. Surgery (2013) 2.43

Pancreatic Cancer Registry in Japan: 20 years of experience. Pancreas (2004) 2.30

A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Anal Chem (2002) 2.18

Laparoscopy-assisted distal gastrectomy with systemic lymph node dissection: a critical reappraisal from the viewpoint of lymph node retrieval. J Am Coll Surg (2004) 2.18

Analysis of mutations within multiple genes associated with resistance in a clinical isolate of Neisseria gonorrhoeae with reduced ceftriaxone susceptibility that shows a multidrug-resistant phenotype. Int J Antimicrob Agents (2005) 2.09

Myocardial velocity gradient as a noninvasively determined index of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol (2003) 2.05

Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension (2006) 2.03

Hepatectomy with portal vein resection for hilar cholangiocarcinoma: audit of 52 consecutive cases. Ann Surg (2003) 2.03

Human mitochondrial DNA is packaged with TFAM. Nucleic Acids Res (2003) 2.01

Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma. Gynecol Oncol (2009) 1.98

Interobserver and intraobserver variability in the diagnosis of hydatidiform mole. Am J Surg Pathol (2005) 1.78

Phase II study of paclitaxel with 3-h infusion in patients with advanced gastric cancer. Gastric Cancer (2002) 1.71

Middle pancreatectomy: safety and long-term results. Surgery (2009) 1.69

Self-assembling peptide nanofiber scaffolds, platelet-rich plasma, and mesenchymal stem cells for injectable bone regeneration with tissue engineering. J Craniofac Surg (2009) 1.67

Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells. Nucleic Acids Res (2002) 1.64

Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats. Hypertension (2005) 1.62

Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosis. Hepatology (2006) 1.61

Pathologic features of mucin-producing bile duct tumors: two histopathologic categories as counterparts of pancreatic intraductal papillary-mucinous neoplasms. Am J Surg Pathol (2004) 1.59

The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin. Chem Biol (2004) 1.59

Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor. J Hepatol (2004) 1.55

Long term parathyroid function following total parathyroidectomy with autotransplantation in adult patients with MEN2A. Endocr J (2009) 1.54

Pilot study on confocal endomicroscopy for determination of the depth of squamous cell esophageal cancer in vivo. J Gastroenterol Hepatol (2009) 1.54

Impact of operative blood loss on survival in invasive ductal adenocarcinoma of the pancreas. Pancreas (2011) 1.52

Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients. J Gastroenterol (2004) 1.52

DeltaNp63 induces beta-catenin nuclear accumulation and signaling. Cancer Cell (2002) 1.51

Possible involvement of the interleukin-15 and interleukin-15 receptor system in a heightened state of lamina propria B cell activation and differentiation in patients with inflammatory bowel disease. J Gastroenterol (2005) 1.50

MACC 1 as a marker for vascular invasive hepatocellular carcinoma. Anticancer Res (2011) 1.48

Clinical significance of regulatory T-cell-related gene expression in peripheral blood after renal transplantation. Transplantation (2011) 1.47

Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination. Clin Cancer Res (2005) 1.47

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma. Clin Cancer Res (2002) 1.46

Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells. Breast Cancer Res Treat (2002) 1.45

Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases. J Biol Chem (2003) 1.44

Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: tissue-engineered bone regeneration. Tissue Eng (2004) 1.44

MACC 1 as a marker for peritoneal-disseminated gastric carcinoma. Anticancer Res (2010) 1.42

Laparoscopic surgery for gastric cancer: a collective review with meta-analysis of randomized trials. J Am Coll Surg (2010) 1.42

Enzyme-linked immunosorbent assay for human leukocyte antigen antibody detection and urine protein test recommended for follow-up monitoring after renal transplantation. Transplantation (2008) 1.40

An engineered Escherichia coli tyrosyl-tRNA synthetase for site-specific incorporation of an unnatural amino acid into proteins in eukaryotic translation and its application in a wheat germ cell-free system. Proc Natl Acad Sci U S A (2002) 1.35

An unnatural base pair for incorporating amino acid analogs into proteins. Nat Biotechnol (2002) 1.35

Assessment of quality of life after gastrectomy using EORTC QLQ-C30 and STO22. World J Surg (2011) 1.33

Japan Pancreatic Cancer Registry; 30th year anniversary: Japan Pancreas Society. Pancreas (2012) 1.31

Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. Clin Cancer Res (2008) 1.30

Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers. Oncogene (2002) 1.28

Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma using double combination array analysis. Ann Surg Oncol (2009) 1.27

Longterm outcomes of early-stage gastric carcinoma patients treated with laparoscopy-assisted surgery. J Am Coll Surg (2007) 1.26

Detection of metallothionein 1G as a methylated tumor suppressor gene in human hepatocellular carcinoma using a novel method of double combination array analysis. Int J Oncol (2009) 1.25

Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy. Gastrointest Endosc (2005) 1.24

Laparoscopy-assisted distal gastrectomy with systemic lymph node dissection for early gastric carcinoma: a review of 43 cases. J Am Coll Surg (2003) 1.21

The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J Biol Chem (2009) 1.21

MACC1 as a marker for advanced colorectal carcinoma. Anticancer Res (2010) 1.21

Only a small subset of the horizontally transferred chromosomal genes in Escherichia coli are translated into proteins. Mol Cell Proteomics (2004) 1.20

Promoter hypermethylation of fibulin 1 gene is associated with tumor progression in hepatocellular carcinoma. Mol Carcinog (2011) 1.20

Multivariate analysis of the pathologic features of esophageal squamous cell cancer: tumor budding is a significant independent prognostic factor. Ann Surg Oncol (2008) 1.19

Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo. Oncogene (2002) 1.19

A phase II study of weekly paclitaxel as second-line chemotherapy for advanced gastric Cancer (CCOG0302 study). Anticancer Res (2007) 1.18

Bone regeneration following injection of mesenchymal stem cells and fibrin glue with a biodegradable scaffold. J Craniomaxillofac Surg (2003) 1.18

Differences between T cell-type and natural killer cell-type chronic active Epstein-Barr virus infection. J Infect Dis (2005) 1.16

Purification of polyglutamine aggregates and identification of elongation factor-1alpha and heat shock protein 84 as aggregate-interacting proteins. J Neurosci (2002) 1.15

Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features. Am J Pathol (2002) 1.15

Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis. Clin Cancer Res (2003) 1.15

Polytetrafluoroethylene prosthesis migration into the bladder after laparoscopic hernia repair: a case report. Surg Laparosc Endosc Percutan Tech (2007) 1.15

Rational use of drugs: prescribing and dispensing practices at public health facilities in Lao PDR. Pharmacoepidemiol Drug Saf (2006) 1.14

Vimentin methylation as a marker for advanced colorectal carcinoma. Anticancer Res (2009) 1.13

The potential of oncolytic virus therapy for pancreatic cancer. Cancer Gene Ther (2005) 1.13

A feasibility study of postoperative chemotherapy with S-1 and cisplatin (CDDP) for gastric carcinoma (CCOG0703). Gastric Cancer (2010) 1.13

Pancreatic cancer with paraaortic lymph node metastasis: a contraindication for radical surgery? Pancreas (2009) 1.11

Xanthogranulomatous inflammation of the colon: a rare cause of cecal mass with bleeding. South Med J (2009) 1.10

Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients. Clin Cancer Res (2002) 1.09

Characterization of in vitro gutlike organ formed from mouse embryonic stem cells. Am J Physiol Cell Physiol (2004) 1.09

Earlier hepatic vein transit-time measured by contrast ultrasonography reflects intrahepatic hemodynamic changes accompanying cirrhosis. J Hepatol (2002) 1.09

Negative pressure external drainage of the pancreatic duct in pancreaticoduodenectomy. Hepatogastroenterology (2010) 1.09

Preservation of the pyloric ring has little value in surgery for pancreatic head cancer: a comparative study comparing three surgical procedures. Ann Surg Oncol (2011) 1.08

Are N-glycolylneuraminic acid (Hanganutziu-Deicher) antigens important in pig-to-human xenotransplantation? Xenotransplantation (2004) 1.06

Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters. J Surg Oncol (2008) 1.06

Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma. Liver Int (2005) 1.06

Para-aortic lymph node metastasis in carcinoma of the head of the pancreas. Surgery (2005) 1.06

Amylase concentration of the drainage fluid as a risk factor for intra-abdominal abscess following gastrectomy for gastric cancer. World J Surg (2010) 1.04

A remarkable reduction in the susceptibility of Neisseria gonorrhoeae isolates to cephems and the selection of antibiotic regimens for the single-dose treatment of gonococcal infection in Japan. J Infect Chemother (2002) 1.04

Role of adjuvant surgery for patients with initially unresectable pancreatic cancer with a long-term favorable response to non-surgical anti-cancer treatments: results of a project study for pancreatic surgery by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci (2013) 1.04

AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats. Hypertension (2002) 1.04

Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma. Clin Exp Metastasis (2007) 1.03

Long-term follow-up and prognostic factor analysis in clear cell adenocarcinoma of the ovary. J Surg Oncol (2006) 1.03

Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells. EMBO J (2009) 1.03

Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging. Proc Natl Acad Sci U S A (2013) 1.03

HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam. BMC Public Health (2006) 1.03

Polyester synthesis genes associated with stress resistance are involved in an insect-bacterium symbiosis. Proc Natl Acad Sci U S A (2013) 1.01

Follow-up surveillance for recurrence after curative gastric cancer surgery lacks survival benefit. Ann Surg Oncol (2003) 1.01