Jonathon D Sedgwick

Author PubWeight™ 75.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003 22.89
2 Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 2003 14.60
3 A critical function for CD200 in lung immune homeostasis and the severity of influenza infection. Nat Immunol 2008 3.34
4 The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation. Curr Opin Immunol 2006 2.98
5 STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest 2008 2.95
6 Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol 2003 2.38
7 Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. J Immunol 2006 1.97
8 Mast cell-associated TNF promotes dendritic cell migration. J Immunol 2006 1.78
9 Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice. J Immunol 2006 1.65
10 Molecular mechanisms of CD200 inhibition of mast cell activation. J Immunol 2004 1.57
11 Regulation of myeloid cell function through the CD200 receptor. J Immunol 2006 1.56
12 Mast cells enhance T cell activation: Importance of mast cell-derived TNF. Proc Natl Acad Sci U S A 2005 1.47
13 Transmembrane TNF is sufficient to initiate cell migration and granuloma formation and provide acute, but not long-term, control of Mycobacterium tuberculosis infection. J Immunol 2005 1.44
14 Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain. J Immunol 2002 1.42
15 Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis. Am J Pathol 2002 1.42
16 A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21. J Immunol 2004 1.27
17 Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependent. J Immunol 2002 1.26
18 Intrinsic renal cells are the major source of tumor necrosis factor contributing to renal injury in murine crescentic glomerulonephritis. J Am Soc Nephrol 2003 1.19
19 Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis. Am J Pathol 2007 1.19
20 CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts. Proc Natl Acad Sci U S A 2007 1.13
21 Regulation of microglial cell responses in murine Toxoplasma encephalitis by CD200/CD200 receptor interaction. Acta Neuropathol 2006 1.04
22 An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance. J Neuropathol Exp Neurol 2005 1.04
23 Involvement of TNF in limiting liver pathology and promoting parasite survival during schistosome infection. Int J Parasitol 2004 0.98
24 Differential requirements by CD4+ and CD8+ T cells for soluble and membrane TNF in control of Francisella tularensis live vaccine strain intramacrophage growth. J Immunol 2007 0.98
25 Membrane tumor necrosis factor confers partial protection to Listeria infection. Am J Pathol 2005 0.97
26 Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge. J Immunol 2005 0.88
27 Membrane lymphotoxin contributes to anti-leishmanial immunity by controlling structural integrity of lymphoid organs. Eur J Immunol 2002 0.87
28 TNF is important for pathogen control and limits brain damage in murine cerebral listeriosis. J Immunol 2006 0.83
29 Loss of TNF signaling facilitates the development of a novel Ly-6C(low) macrophage population permissive for Leishmania major infection. J Immunol 2012 0.82