Published in Am J Physiol Gastrointest Liver Physiol on February 01, 2002
Expression of human arginine decarboxylase, the biosynthetic enzyme for agmatine. Biochim Biophys Acta (2004) 1.00
Putrescine biosynthesis in mammalian tissues. Biochem J (2004) 0.99
Localization and differential expression of arginase II in the kidney of male and female mice. Pflugers Arch (2004) 0.92
Supraspinally-administered agmatine attenuates the development of oral fentanyl self-administration. Eur J Pharmacol (2008) 0.87
Enzymes of urea synthesis are expressed at the ocular surface, and decreased urea in the tear fluid is associated with dry-eye syndrome. Graefes Arch Clin Exp Ophthalmol (2013) 0.78
Cloning of two LIMCH1 isoforms: characterization of their distribution in rat brain and their agmatinase activity. Histochem Cell Biol (2015) 0.77
Agmatine is transported into liver mitochondria by a specific electrophoretic mechanism. Biochem J (2006) 0.76
The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBPβ rather than Enterotoxigenic Bacteroides fragilis Infection. Oxid Med Cell Longev (2016) 0.76
Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.75
Expression and localization of an agmatinase-like protein in the rat brain. Histochem Cell Biol (2010) 0.75
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA (2005) 6.14
Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med (2003) 2.93
Decreased arginine bioavailability and increased serum arginase activity in asthma. Am J Respir Crit Care Med (2004) 2.01
Induction of arginase I transcription by IL-4 requires a composite DNA response element for STAT6 and C/EBPbeta. Gene (2005) 2.00
Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox. Proc Natl Acad Sci U S A (2003) 1.92
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. J Biol Chem (2005) 1.74
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. J Immunol (2013) 1.62
Adenosine promotes alternative macrophage activation via A2A and A2B receptors. FASEB J (2011) 1.38
Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol (2010) 1.35
Activities of arginase I and II are limiting for endothelial cell proliferation. Am J Physiol Regul Integr Comp Physiol (2002) 1.35
Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats. J Clin Invest (2011) 1.30
Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease. Circulation (2007) 1.29
Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase. J Immunol (2011) 1.26
Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease. J Pediatr Hematol Oncol (2003) 1.14
Macrophage arginase regulation by CCAAT/enhancer-binding protein beta. Shock (2005) 1.11
Inhibition of phosphodiesterase 4 amplifies cytokine-dependent induction of arginase in macrophages. Am J Physiol Lung Cell Mol Physiol (2005) 1.05
Detection of activity centers in cellular pathways using transcript profiling. J Biopharm Stat (2004) 1.00
Determination of mammalian arginase activity. Methods Enzymol (2008) 0.96
LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8. Circ Res (2011) 0.96
Retinoic acid promotes the development of Arg1-expressing dendritic cells for the regulation of T-cell differentiation. Eur J Immunol (2013) 0.95
Thrombin induces endothelial arginase through AP-1 activation. Am J Physiol Cell Physiol (2009) 0.95
The central role of arginine catabolism in T-cell dysfunction and increased susceptibility to infection after physical injury. Ann Surg (2014) 0.94
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets. PLoS One (2010) 0.90
Shaping the murine macrophage phenotype: IL-4 and cyclic AMP synergistically activate the arginase I promoter. J Immunol (2013) 0.87
Biochemical responses of healthy subjects during dietary supplementation with L-arginine. J Nutr Biochem (2004) 0.87
Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury. Urology (2008) 0.87
Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism. Kidney Int (2013) 0.87
The 'intestinal-renal' arginine biosynthetic axis in the aging rat. Mech Ageing Dev (2002) 0.86
Cell- and isoform-specific increases in arginase expression in acute silica-induced pulmonary inflammation. J Toxicol Environ Health A (2007) 0.82
Selective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in mice. PLoS One (2012) 0.81
From inflammation to wound healing: using a simple model to understand the functional versatility of murine macrophages. Bull Math Biol (2011) 0.75
A proposal for an upper limit of leucine safe intake in healthy adults. J Nutr (2012) 0.75