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1
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Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy.
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J Clin Invest
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2007
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3.28
|
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2
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Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.
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J Clin Invest
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2007
|
2.80
|
|
3
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Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
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Blood
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2006
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1.98
|
|
4
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Chance or necessity? Insertional mutagenesis in gene therapy and its consequences.
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Mol Ther
|
2004
|
1.65
|
|
5
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Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.
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Blood
|
2005
|
1.29
|
|
6
|
Gene therapy: is IL2RG oncogenic in T-cell development?
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Nature
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2006
|
1.18
|
|
7
|
Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy.
|
Mol Ther
|
2011
|
1.04
|
|
8
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New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy.
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Mol Ther
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2007
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1.00
|
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9
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An inventory of shedding data from clinical gene therapy trials.
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J Gene Med
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2007
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1.00
|
|
10
|
In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice.
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PLoS One
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2013
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0.93
|
|
11
|
Long-term effects of irradiation before adulthood on reproductive function in the male rhesus monkey.
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Biol Reprod
|
2002
|
0.93
|
|
12
|
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype.
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Blood
|
2010
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0.92
|
|
13
|
New TPO treatment schedules of increased safety and efficacy: pre-clinical validation of a thrombopoiesis simulation model.
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Br J Haematol
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2003
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0.91
|
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14
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Delayed effects of accidental cutaneous radiation exposure: fifteen years of follow-up after the Chernobyl accident.
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J Am Acad Dermatol
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2003
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0.90
|
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15
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Correction of murine SCID-X1 by lentiviral gene therapy using a codon-optimized IL2RG gene and minimal pretransplant conditioning.
|
Mol Ther
|
2011
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0.88
|
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16
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Flt3 ligand expands lymphoid progenitors prior to recovery of thymopoiesis and accelerates T cell reconstitution after bone marrow transplantation.
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J Immunol
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2007
|
0.88
|
|
17
|
Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene.
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Mol Ther
|
2012
|
0.87
|
|
18
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Mobilization of hepatic mesenchymal stem cells from human liver grafts.
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Liver Transpl
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2011
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0.84
|
|
19
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Magselectofection: an integrated method of nanomagnetic separation and genetic modification of target cells.
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Blood
|
2011
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0.83
|
|
20
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Comprehensive investigation of parameter choice in viral integration site analysis and its effects on the gene annotations produced.
|
Hum Gene Ther
|
2012
|
0.83
|
|
21
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Overestimation of hematopoietic stem cell frequencies in human liver grafts.
|
Hepatology
|
2013
|
0.78
|
|
22
|
Keratinocyte growth factor and stem cell factor to improve thymopoiesis after autologous CD34+ cell transplantation in rhesus macaques.
|
Biol Blood Marrow Transplant
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2011
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0.78
|
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23
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Co-administration of Flt-3 ligand counteracts the actions of thrombopoietin in myelosuppressed rhesus monkeys.
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Br J Haematol
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2003
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0.77
|
|
24
|
Stable changes in mesenchymal stromal cells from multiple myeloma patients revealed through their responses to Toll-like receptor ligands and epidermal growth factor.
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Stem Cell Rev
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2012
|
0.77
|
|
25
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Lentiviral gene transduction of mouse and human hematopoietic stem cells.
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Methods Mol Biol
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2014
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0.77
|
|
26
|
Pretransplant mobilization with granulocyte colony-stimulating factor improves B-cell reconstitution by lentiviral vector gene therapy in SCID-X1 mice.
|
Hum Gene Ther
|
2014
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0.76
|
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27
|
5-Androstene-3β,17β-diol promotes recovery of immature hematopoietic cells following myelosuppressive radiation and synergizes with thrombopoietin.
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Int J Radiat Oncol Biol Phys
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2012
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0.76
|
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28
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Thrombopoietin is a major limiting factor for selective outgrowth of human umbilical cord blood cells in non-obese diabetic/severe combined immunodeficient recipient mice.
|
Br J Haematol
|
2003
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0.75
|
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29
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Erratum to "New Insights and Unresolved Issues Regarding Insertional Mutagenesis in X-linked SCID Gene Therapy".
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Mol Ther
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2016
|
0.75
|
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30
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Ticlopidine inhibits the prothrombotic effects of thrombopoietin and ameliorates survival after supralethal total body irradiation.
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Thromb Haemost
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2002
|
0.75
|