Published in Nat Med on February 01, 2002
Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Nat Med (2008) 4.83
Endothelial cell diversity revealed by global expression profiling. Proc Natl Acad Sci U S A (2003) 3.98
Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chem Soc Rev (2012) 3.34
Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study. Cancer (2015) 2.13
Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors. Proc Natl Acad Sci U S A (2015) 2.12
Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish. Nat Chem Biol (2006) 2.08
Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev (2006) 1.92
Endothelial cell heterogeneity. Cold Spring Harb Perspect Med (2012) 1.88
State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proc Am Thorac Soc (2006) 1.75
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. Sci Transl Med (2011) 1.74
Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents. Proc Natl Acad Sci U S A (2006) 1.73
Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. PLoS One (2009) 1.66
In vivo imaging of molecularly targeted phage. Neoplasia (2006) 1.59
Plasmodium falciparum picks (on) EPCR. Blood (2013) 1.53
Screening phage display libraries for organ-specific vascular immunotargeting in vivo. Proc Natl Acad Sci U S A (2005) 1.46
The neovasculature homing motif NGR: more than meets the eye. Blood (2008) 1.46
Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. J Biol Chem (2008) 1.44
High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. J Am Chem Soc (2010) 1.41
Mesenchymal stem cells and cardiac repair. J Cell Mol Med (2008) 1.37
Phage display in molecular imaging and diagnosis of cancer. Chem Rev (2010) 1.34
Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc Natl Acad Sci U S A (2009) 1.24
Marker rescue of adeno-associated virus (AAV) capsid mutants: a novel approach for chimeric AAV production. J Virol (2003) 1.24
Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications. Curr Pharm Des (2010) 1.23
Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am J Pathol (2005) 1.22
Borrelia burgdorferi adhesins identified using in vivo phage display. Mol Microbiol (2007) 1.17
IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells. Stem Cells (2008) 1.16
Genetically modified T cells targeting interleukin-11 receptor α-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res (2011) 1.15
A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proc Natl Acad Sci U S A (2008) 1.14
The Use of Phage-Displayed Peptide Libraries to Develop Tumor-Targeting Drugs. Int J Pept Res Ther (2006) 1.11
Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A (2011) 1.09
An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment. Proc Natl Acad Sci U S A (2009) 1.07
Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries. PLoS One (2009) 1.07
Combinatorial peptide libraries: mining for cell-binding peptides. Chem Rev (2013) 1.07
Combinatorial ligand-directed lung targeting. Proc Am Thorac Soc (2009) 1.07
Prospective identification of parasitic sequences in phage display screens. Nucleic Acids Res (2013) 1.05
Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome. J Control Release (2010) 1.04
Expression and function of interleukin-11 and its receptor alpha in the human endometrium. Mol Hum Reprod (2003) 1.02
Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. J Biol Chem (2008) 1.01
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest (2010) 1.00
Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls. J Oncol (2010) 0.97
Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo. Diabetes (2009) 0.97
Fishing for novel angiogenic therapies. Br J Pharmacol (2003) 0.97
A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11. PLoS One (2008) 0.96
Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites. Antimicrob Agents Chemother (2012) 0.95
A peptide probe for targeted brown adipose tissue imaging. Nat Commun (2013) 0.94
Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease. Mol Ther (2012) 0.93
Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A (2013) 0.93
Endothelial cells derived from nuclear reprogramming. Circ Res (2012) 0.93
Screening and identification of a targeting peptide to hepatocarcinoma from a phage display peptide library. Mol Med (2007) 0.92
A novel peptide (GX1) homing to gastric cancer vasculature inhibits angiogenesis and cooperates with TNF alpha in anti-tumor therapy. BMC Cell Biol (2009) 0.92
A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med (2012) 0.91
Semiparametric Bayesian inference for phage display data. Biometrics (2013) 0.90
Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development. Cell Death Differ (2014) 0.90
E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal-Tailored Acceleration of AAV Evolution. Mol Ther (2015) 0.90
Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells. Nat Commun (2012) 0.89
Transcriptional profiling of human cavernosal endothelial cells reveals distinctive cell adhesion phenotype and role for claudin 11 in vascular barrier function. Physiol Genomics (2009) 0.88
Teratogenicity induced by targeting a placental immunoglobulin transporter. Proc Natl Acad Sci U S A (2002) 0.87
Recombinant peptides as biomarkers for tumor response to molecular targeted therapy. Clin Cancer Res (2009) 0.87
Potential of phage-displayed peptide library technology to identify functional targeting peptides. Expert Opin Drug Discov (2007) 0.87
Uniform amplification of phage with different growth characteristics in individual compartments consisting of monodisperse droplets. Angew Chem Int Ed Engl (2010) 0.87
Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo. PLoS One (2011) 0.86
Development of a ligand-directed approach to study the pathogenesis of invasive aspergillosis. Infect Immun (2005) 0.86
Two-step fluorescence screening of CD21-binding peptides with one-bead one-compound library and investigation of binding properties of N-(2-hydroxypropyl)methacrylamide copolymer-peptide conjugates. Biomacromolecules (2006) 0.84
Enhanced expression of CD13 in vessels of inflammatory and neoplastic tissues. J Histochem Cytochem (2011) 0.84
Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy. J Oncol (2010) 0.84
Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro. Front Immunol (2013) 0.82
Techniques for molecular imaging probe design. Mol Imaging (2011) 0.82
Error analysis of deep sequencing of phage libraries: peptides censored in sequencing. Comput Math Methods Med (2013) 0.82
Phage display--a powerful technique for immunotherapy: 1. Introduction and potential of therapeutic applications. Hum Vaccin Immunother (2012) 0.81
A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody. J Cell Physiol (2010) 0.81
Charting the course across the blood-brain barrier. J Clin Invest (2010) 0.81
Tumor angiogenesis-characteristics of tumor endothelial cells. Int J Clin Oncol (2016) 0.81
Infectivity-selective oncolytic adenovirus developed by high-throughput screening of adenovirus-formatted library. Mol Ther (2012) 0.80
Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions. PLoS One (2013) 0.80
Phage Peptide Libraries As a Source of Targeted Ligands. Acta Naturae (2016) 0.80
Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clin Cancer Res (2015) 0.80
A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices. Fibrogenesis Tissue Repair (2011) 0.79
Identification of novel immunoregulatory molecules in human thymic regulatory CD4+CD25+ T cells by phage display. PLoS One (2011) 0.79
Targeting mammalian organelles with internalizing phage (iPhage) libraries. Nat Protoc (2013) 0.79
Identification of tissue-specific targeting peptide. J Comput Aided Mol Des (2012) 0.78
Development of a peptide by phage display for SPECT imaging of resistance-susceptible breast cancer. Am J Nucl Med Mol Imaging (2014) 0.78
Generation of recombinant antibodies to rat GABAA receptor subunits by affinity selection on synthetic peptides. PLoS One (2014) 0.78
Nanotechnology in interventional cardiology. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2011) 0.78
Phage as a Genetically Modifiable Supramacromolecule in Chemistry, Materials and Medicine. Acc Chem Res (2016) 0.78
Deformable Discoidal Polymeric Nanoconstructs for the Precise Delivery of Therapeutic and Imaging Agents. Mol Ther (2017) 0.78
Advancement and applications of peptide phage display technology in biomedical science. J Biomed Sci (2016) 0.78
Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity. Am J Pathol (2016) 0.78
Design of virus-based nanomaterials for medicine, biotechnology, and energy. Chem Soc Rev (2016) 0.77
Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo. Mol Ther Nucleic Acids (2014) 0.77
Strategic workshops on cancer nanotechnology. Cancer Res (2010) 0.77
Ligand-targeted theranostic nanomedicines against cancer. J Control Release (2016) 0.77
Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancer. Viruses (2014) 0.77
In vivo phage display selection of an ovarian cancer targeting peptide for SPECT/CT imaging. Am J Nucl Med Mol Imaging (2014) 0.77
Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor. PLoS One (2015) 0.77
Isolation of specific peptides that home to dorsal root ganglion neurons in mice. Neurosci Lett (2008) 0.77
Phage-Enabled Nanomedicine: From Probes to Therapeutics in Precision Medicine. Angew Chem Int Ed Engl (2017) 0.77
A tale of mice and (wo)men: development of and insights from an "all human" animal model of breast cancer metastasis to bone. Trans Am Clin Climatol Assoc (2012) 0.76
Zip codes: deciphering vascular addresses. Nat Med (2002) 0.76
Selection strategies for anticancer antibody discovery: searching off the beaten path. Trends Biotechnol (2015) 0.76
Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. PLoS One (2013) 0.76
Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med (2011) 27.58
Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med (2012) 15.69
The BATTLE trial: personalizing therapy for lung cancer. Cancer Discov (2011) 7.57
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol (2012) 6.49
Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia. Blood (2008) 6.39
Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest (2006) 6.12
Personalized oncology through integrative high-throughput sequencing: a pilot study. Sci Transl Med (2011) 5.82
Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone. J Clin Oncol (2011) 4.57
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol (2009) 4.54
A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res (2007) 4.34
Feature extraction and quantification for mass spectrometry in biomedical applications using the mean spectrum. Bioinformatics (2005) 4.26
Reversal of obesity by targeted ablation of adipose tissue. Nat Med (2004) 4.23
Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia. J Clin Oncol (2005) 4.06
A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors. Cancer Res (2004) 3.63
Simplified staging for hepatocellular carcinoma. J Clin Oncol (2002) 3.48
Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol (2009) 3.39
Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial. Lancet Oncol (2013) 3.38
Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat Biotechnol (2002) 3.32
Genetic basis for in vivo daptomycin resistance in enterococci. N Engl J Med (2011) 3.20
Non-parametric quantification of protein lysate arrays. Bioinformatics (2007) 3.18
Intravascular delivery of particulate systems: does geometry really matter? Pharm Res (2008) 3.13
Gelatinase-mediated migration and invasion of cancer cells. Biochim Biophys Acta (2005) 3.06
CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients. Proc Natl Acad Sci U S A (2008) 3.04
Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. J Clin Oncol (2009) 3.02
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol (2004) 3.02
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat Biotechnol (2003) 3.01
A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. Cancer Res (2009) 3.00
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands. Cancer Cell (2004) 2.99
Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon. Clin Cancer Res (2005) 2.98
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res (2004) 2.96
Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia. Blood (2007) 2.91
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell (2013) 2.81
Improved peak detection and quantification of mass spectrometry data acquired from surface-enhanced laser desorption and ionization by denoising spectra with the undecimated discrete wavelet transform. Proteomics (2005) 2.81
Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res (2010) 2.73
Surgical resection of gastrointestinal stromal tumors after treatment with imatinib. Ann Surg Oncol (2007) 2.72
Soft tissue sarcomas. CA Cancer J Clin (2004) 2.65
Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy: an analysis of 1225 patients. Cancer (2003) 2.64
Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer. Clin Cancer Res (2011) 2.64
Breast cancer on the world wide web: cross sectional survey of quality of information and popularity of websites. BMJ (2002) 2.53
Long-term complications associated with breast-conservation surgery and radiotherapy. Ann Surg Oncol (2002) 2.51
Career satisfaction, practice patterns and burnout among surgical oncologists: report on the quality of life of members of the Society of Surgical Oncology. Ann Surg Oncol (2007) 2.50
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature (2010) 2.49
Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors. Am J Pathol (2008) 2.48
Use of research biopsies in clinical trials: are risks and benefits adequately discussed? J Clin Oncol (2012) 2.43
Long-term results of two prospective trials of preoperative external beam radiotherapy for localized intermediate- or high-grade retroperitoneal soft tissue sarcoma. Ann Surg Oncol (2006) 2.43
Microarrays: retracing steps. Nat Med (2007) 2.39
A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis. Ann Surg Oncol (2008) 2.39
Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas. Proc Natl Acad Sci U S A (2007) 2.38
Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst (2009) 2.34
Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes. Clin Cancer Res (2013) 2.30
The seed and soil hypothesis: vascularisation and brain metastases. Lancet Oncol (2002) 2.27
Optimizing treatment of desmoid tumors. J Clin Oncol (2007) 2.27
Phase II study of abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer displaying bone flare discordant with serologic response. Clin Cancer Res (2011) 2.23
Body surface area and body weight predict total liver volume in Western adults. Liver Transpl (2002) 2.21
A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell (2006) 2.20
Obesity, weight gain, and risk of biochemical failure among prostate cancer patients following prostatectomy. Clin Cancer Res (2005) 2.14
Extraosseous osteosarcoma: response to treatment and long-term outcome. J Clin Oncol (2002) 2.13
Three-dimensional tissue culture based on magnetic cell levitation. Nat Nanotechnol (2010) 2.11
Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. J Clin Oncol (2004) 2.10
The importance of experimental design in proteomic mass spectrometry experiments: some cautionary tales. Brief Funct Genomic Proteomic (2005) 2.08
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg (2009) 2.04
Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the M.D. Anderson experience. Cancer J (2003) 2.02
Targeting the prostate for destruction through a vascular address. Proc Natl Acad Sci U S A (2002) 2.01
Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression. J Biol Chem (2006) 2.01
Bayesian analysis of mass spectrometry proteomic data using wavelet-based functional mixed models. Biometrics (2007) 2.01
PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates for active surveillance. J Urol (2008) 2.00
Serum proteomics profiling--a young technology begins to mature. Nat Biotechnol (2005) 1.98
Angiosarcoma of the breast. Cancer (2005) 1.98
Novel therapies for metastatic castrate-resistant prostate cancer. J Natl Cancer Inst (2011) 1.98
Run batch effects potentially compromise the usefulness of genomic signatures for ovarian cancer. J Clin Oncol (2008) 1.96
Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer. J Clin Oncol (2011) 1.96
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin Cancer Res (2005) 1.95
Prostate carcinoma with testicular or penile metastases. Clinical, pathologic, and immunohistochemical features. Cancer (2002) 1.95
Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev (2006) 1.92
Bayesian and frequentist two-stage treatment strategies based on sequential failure times subject to interval censoring. Stat Med (2007) 1.92
Prostate cancer of transition zone origin lacks TMPRSS2-ERG gene fusion. Mod Pathol (2009) 1.90
Quality control and peak finding for proteomics data collected from nipple aspirate fluid by surface-enhanced laser desorption and ionization. Clin Chem (2003) 1.88
Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clin Cancer Res (2002) 1.88
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest (2008) 1.87
Splenic arterial interventions: anatomy, indications, technical considerations, and potential complications. Radiographics (2005) 1.85
Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications. Radiographics (2005) 1.85