Selection for fitness versus selection for robustness in RNA secondary structure folding.

PubWeight™: 1.46‹?› | Rank: Top 5%

🔗 View Article (PMID 11831657)

Published in Evolution on December 01, 2001

Authors

C O Wilke1

Author Affiliations

1: Digital Life Laboratory, California Institute of Technology, Pasadena 91125, USA. wilke@caltech.edu

Articles citing this

Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life. Phys Life Rev (2012) 6.08

Quasispecies theory in the context of population genetics. BMC Evol Biol (2005) 2.02

Selection for robustness in mutagenized RNA viruses. PLoS Genet (2007) 1.58

Quasispecies made simple. PLoS Comput Biol (2005) 1.56

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences. J Virol (2005) 1.46

The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens. PLoS Pathog (2006) 1.35

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding. BMC Evol Biol (2003) 1.34

Evolution of complexity in RNA-like replicator systems. Biol Direct (2008) 1.27

Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Evol Biol (2008) 1.25

Multilevel selection in models of prebiotic evolution II: a direct comparison of compartmentalization and spatial self-organization. PLoS Comput Biol (2009) 1.17

Phenotypic error threshold; additivity and epistasis in RNA evolution. BMC Evol Biol (2005) 1.17

The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation. Genetics (2009) 1.12

Fitness declines in Tobacco etch virus upon serial bottleneck transfers. J Virol (2007) 1.11

Lethal mutagenesis of bacteria. Genetics (2008) 1.05

The relationship between the error catastrophe, survival of the flattest, and natural selection. BMC Evol Biol (2011) 1.04

Phenotypic mixing and hiding may contribute to memory in viral quasispecies. BMC Microbiol (2003) 1.02

Collective properties of evolving molecular quasispecies. BMC Evol Biol (2007) 0.95

Exact solution of the Eigen model with general fitness functions and degradation rates. Proc Natl Acad Sci U S A (2006) 0.94

Modular evolution and increase of functional complexity in replicating RNA molecules. RNA (2006) 0.89

Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations? PLoS Comput Biol (2010) 0.83

Recombination in primeval genomes: a step forward but still a long leap from maintaining a sizable genome. J Mol Evol (2004) 0.81

The origin of a primordial genome through spontaneous symmetry breaking. Nat Commun (2017) 0.78

Lethal mutants and truncated selection together solve a paradox of the origin of life. PLoS One (2011) 0.78

Quasi-species evolution in subdivided populations favours maximally deleterious mutations. Proc Biol Sci (2007) 0.77

Congruent evolution of fitness and genetic robustness in vesicular stomatitis virus. J Virol (2013) 0.77

Interactions between evolutionary processes at high mutation rates. Evolution (2012) 0.76

Tipping points and early warning signals in the genomic composition of populations induced by environmental changes. Sci Rep (2015) 0.75

Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations. Sci Rep (2014) 0.75

Critical mutation rate has an exponential dependence on population size in haploid and diploid populations. PLoS One (2013) 0.75

Conditioning and Robustness of RNA Boltzmann Sampling under Thermodynamic Parameter Perturbations. Biophys J (2017) 0.75