Published in Lancet on February 09, 2002
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ (2013) 9.01
Tonsillectomy versus watchful waiting in recurrent streptococcal pharyngitis in adults: randomised controlled trial. BMJ (2007) 2.97
Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial. JAMA (2015) 2.78
Targets and self monitoring in hypertension: randomised controlled trial and cost effectiveness analysis. BMJ (2005) 2.41
Issues in outcomes research: an overview of randomization techniques for clinical trials. J Athl Train (2008) 2.18
Differences in young people's reports of sexual behaviors according to interview methodology: a randomized trial in India. Am J Public Health (2007) 1.73
Randomised controlled trials in Africa of HIV and AIDS: descriptive study and spatial distribution. BMJ (2005) 1.68
Methodological reporting quality of randomized controlled trials in three spine journals from 2010 to 2012. Eur Spine J (2014) 1.55
Oral purified bacterial extracts in acute respiratory tract infections in childhood: a systematic quantitative review. Eur J Pediatr (2006) 1.50
Randomised trial support for orthopaedic surgical procedures. PLoS One (2014) 1.42
The hierarchy of evidence: Levels and grades of recommendation. Indian J Orthop (2007) 1.37
Worth adapting? Revisiting the usefulness of outcome-adaptive randomization. Clin Cancer Res (2012) 1.33
Risk of infection in patients with lymphoma receiving rituximab: systematic review and meta-analysis. BMC Med (2011) 1.21
Is restricted randomisation necessary? BMJ (2006) 1.17
Evidence at a glance: error matrix approach for overviewing available evidence. BMC Med Res Methodol (2010) 1.16
Optimizing real time fMRI neurofeedback for therapeutic discovery and development. Neuroimage Clin (2014) 1.12
Diffusion of an evidence-based smoking cessation intervention through Facebook: a randomised controlled trial study protocol. BMJ Open (2014) 1.07
Drug use and HIV risk outcomes in opioid-injecting men in the Republic of Georgia: behavioral treatment + naltrexone compared to usual care. Drug Alcohol Depend (2011) 1.02
Microfracture technique versus osteochondral autologous transplantation mosaicplasty in patients with articular chondral lesions of the knee: a prospective randomized trial with long-term follow-up. Knee Surg Sports Traumatol Arthrosc (2014) 0.95
Tonic and phasic alertness training: a novel behavioral therapy to improve spatial and non-spatial attention in patients with hemispatial neglect. Front Hum Neurosci (2010) 0.95
Planning a clinical research study. Indian J Orthop (2007) 0.95
Interventions for encouraging sexual behaviours intended to prevent cervical cancer. Cochrane Database Syst Rev (2011) 0.94
Revisiting the design of phase III clinical trials of antimalarial drugs for uncomplicated Plasmodium falciparum malaria. PLoS Med (2008) 0.94
Bicycling to school improves the cardiometabolic risk factor profile: a randomised controlled trial. BMJ Open (2012) 0.93
Training Primary Care Physicians to Employ Self-Efficacy-Enhancing Interviewing Techniques: Randomized Controlled Trial of a Standardized Patient Intervention. J Gen Intern Med (2016) 0.92
Sexual risk behaviors, circumcision status, and preexisting immunity to adenovirus type 5 among men who have sex with men participating in a randomized HIV-1 vaccine efficacy trial: step study. J Acquir Immune Defic Syndr (2012) 0.92
Interpreting meta-analysis according to the adequacy of sample size. An example using isoniazid chemoprophylaxis for tuberculosis in purified protein derivative negative HIV-infected individuals. Clin Epidemiol (2010) 0.92
Sociopsychological tailoring to address colorectal cancer screening disparities: a randomized controlled trial. Ann Fam Med (2014) 0.91
Neglected external validity in reports of randomized trials: the example of hip and knee osteoarthritis. Arthritis Rheum (2009) 0.90
Preparing for the unexpected: the pivotal role of social and behavioral sciences in trials of biomedical HIV prevention interventions. J Acquir Immune Defic Syndr (2013) 0.90
Patient-specific computer-based decision support in primary healthcare--a randomized trial. Implement Sci (2014) 0.90
Randomized controlled trial of computerized cognitive behavioural therapy for depressive symptoms: effectiveness and costs of a workplace intervention. Psychol Med (2014) 0.90
INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY). Am Heart J (2013) 0.90
Transforming growth factor-β inhibition attenuates pulmonary arterial hypertension in rats. Int J Clin Exp Med (2010) 0.87
A pilot randomized controlled trial of the feasibility of a self-directed coping skills intervention for couples facing prostate cancer: rationale and design. Health Qual Life Outcomes (2012) 0.87
Pralidoxime for organophosphate poisoning. Lancet (2006) 0.86
The reporting of methods for reducing and detecting bias: an example from the WHO Misoprostol Third Stage of Labour equivalence randomised controlled trial. BMC Med Res Methodol (2003) 0.86
Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment. BMJ Open (2016) 0.85
Discontinuing inappropriate medication in nursing home residents (DIM-NHR Study): protocol of a cluster randomised controlled trial. BMJ Open (2014) 0.85
Diffusion of an Evidence-Based Smoking Cessation Intervention Through Facebook: A Randomized Controlled Trial. Am J Public Health (2016) 0.85
The effects of two health information texts on patient recognition memory: a randomized controlled trial. Patient Educ Couns (2013) 0.85
Strength-balance supplemented with computerized cognitive training to improve dual task gait and divided attention in older adults: a multicenter randomized-controlled trial. BMC Geriatr (2014) 0.85
Antimicrobial agent exposure and the emergence and spread of resistant microorganisms: issues associated with study design. Eur J Clin Microbiol Infect Dis (2012) 0.85
Comparison of the clinical effectiveness between the streamlined liner of pharyngeal airway (SLIPA) and the laryngeal mask airway by novice personnel. Korean J Anesthesiol (2012) 0.84
Breast cancer: from "maximum tolerable" to "minimum effective" treatment. Front Oncol (2012) 0.84
Study protocol of the YOU CALL--WE CALL TRIAL: impact of a multimodal support intervention after a "mild" stroke. BMC Neurol (2010) 0.83
Practical tips for surgical research. Ensuring balanced groups in surgical trials. Can J Surg (2010) 0.82
Methodological Reporting Quality of Randomized Controlled Trials in 3 Leading Diabetes Journals From 2011 to 2013 Following CONSORT Statement: A System Review. Medicine (Baltimore) (2015) 0.82
Clinical research methodology I: introduction to randomized trials. J Am Coll Surg (2008) 0.82
Is acupuncture no more than a placebo? Extensive discussion required about possible bias. Exp Ther Med (2015) 0.81
The revised position papers on gastric decontamination. Clin Toxicol (Phila) (2005) 0.80
HIV prevention in favour of the choice-disabled in southern Africa: study protocol for a randomised controlled trial. Trials (2013) 0.80
Improving psychotherapy research: The example of mindfulness based interventions. World J Methodol (2011) 0.79
Slow injection of nefopam reduces pain intensity associated with intravenous injection: a prospective randomized trial. J Anesth (2013) 0.79
Endurance training modifies exercise-induced activation of blood coagulation: RCT. Eur J Appl Physiol (2012) 0.79
Randomized controlled trials of malaria intervention trials in Africa, 1948 to 2007: a descriptive analysis. Malar J (2011) 0.79
Long-term behavior of double crown retained dentures with metal and metal-free secondary crowns and frameworks made of Vectris(©) on all-ceramic primary crowns: a prospective, randomized clinical trial up to 14 years. Clin Oral Investig (2015) 0.78
Visual feedback training in young karate athletes. Muscles Ligaments Tendons J (2014) 0.78
The role of secondary cytoreductive surgery in patients with recurrent epithelial ovarian, tubal, and peritoneal cancers: a comparative effectiveness analysis. Oncologist (2012) 0.78
Quantifying bias in randomized controlled trials in child health: a meta-epidemiological study. PLoS One (2014) 0.78
Effectiveness of weekly cognitive stimulation therapy for people with dementia and the additional impact of enhancing cognitive stimulation therapy with a carer training program. Clin Interv Aging (2014) 0.77
Brain natriuretic peptide in the evaluation of emergency department dyspnea: is there a role? J Emerg Med (2011) 0.77
Pharmacist intervention in improving hypertension-related knowledge, treatment medication adherence and health-related quality of life: a non-clinical randomized controlled trial. Health Expect (2013) 0.77
Protocol: Effect of intravitreal bevacizumab (avastin) in the treatment of macular edema: A systematic review of randomized controlled trials. J Res Med Sci (2012) 0.76
The PROblem Gambling RESearch Study (PROGRESS) research protocol: a pragmatic randomised controlled trial of psychological interventions for problem gambling. BMJ Open (2015) 0.76
The use of nanocrystalline and two other forms of calcium sulfate in the treatment of infrabony defects: A clinical and radiographic study. J Indian Soc Periodontol (2015) 0.75
Randomized controlled trials - a matter of design. Neuropsychiatr Dis Treat (2016) 0.75
The effect of neural mobilisation on cervico-brachial pain: design of a randomised controlled trial. BMC Musculoskelet Disord (2014) 0.75
A prospective 2-site parallel intervention trial of a research-based film to increase exercise amongst older hemodialysis patients. BMC Nephrol (2017) 0.75
Repeated Sprint Ability in Young Basketball Players (Part 2): The Chronic Effects of Multidirection and of One Change of Direction Are Comparable in Terms of Physiological and Performance Responses. Front Physiol (2016) 0.75
The development of swimming power. Muscles Ligaments Tendons J (2015) 0.75
Which dressing do donor site wounds need?: study protocol for a randomized controlled trial. Trials (2011) 0.75
Chinese Interpreting Studies: a data-driven analysis of a dynamic field of enquiry. PeerJ (2015) 0.75
Aspirin therapy in preeclampsia: more questions than answers. Croat Med J (2006) 0.75
Early treatment of posterior crossbite--a randomised clinical trial. Trials (2013) 0.75
The effects of tailoring knowledge acquisition on colorectal cancer screening self-efficacy. J Health Commun (2015) 0.75
Training Cameroonian researchers on pragmatic knowledge translation trials: a workshop report. Pan Afr Med J (2014) 0.75
The utility of bispectral index monitoring for prevention of rocuronium-induced withdrawal movement in children: A randomized controlled trial. Medicine (Baltimore) (2017) 0.75
Sustainable healthy eating behaviour of young adults: towards a novel methodological approach. BMC Public Health (2016) 0.75
Blocking for Sequential Political Experiments. Polit Anal (2013) 0.75
Treatment of clozapine-associated obesity and diabetes with exenatide (CODEX) in adults with schizophrenia: study protocol for a pilot randomised controlled trial. BJPsych Open (2015) 0.75
How to improve assessment of balance in baseline characteristics of clinical trial participants-example from PROSEVA trial data? Ann Transl Med (2016) 0.75
Stanford's Outcomes Research in Kids (STORK): a prospective study of healthy pregnant women and their babies in Northern California. BMJ Open (2016) 0.75
Delivery of self training and education for stressful situations (DESTRESS-PC): a randomized trial of nurse assisted online self-management for PTSD in primary care. Gen Hosp Psychiatry (2015) 0.75
The effect of uphill stride manipulation on race walking gait. Biol Sport (2015) 0.75
The effect of the facilitated tucking position in reducing vaccination-induced pain in newborns. Ital J Pediatr (2015) 0.75
Epidemiology research. Lancet (2002) 0.75
Do picture-based charts overestimate visual acuity? Comparison of Kay Pictures, Lea Symbols, HOTV and Keeler logMAR charts with Sloan letters in adults and children. PLoS One (2017) 0.75
Narrative exposure therapy for immigrant children traumatized by war: study protocol for a randomized controlled trial of effectiveness and mechanisms of change. BMC Psychiatry (2015) 0.75
Letters to the Editor. J Athl Train (2003) 0.75
Effects of Assist-As-Needed Upper Extremity Robotic Therapy after Incomplete Spinal Cord Injury: A Parallel-Group Controlled Trial. Front Neurorobot (2017) 0.75
Blinding in randomised trials: hiding who got what. Lancet (2002) 5.47
Allocation concealment in randomised trials: defending against deciphering. Lancet (2002) 4.71
The comparative safety of legal induced abortion and childbirth in the United States. Obstet Gynecol (2012) 4.50
Sample size calculations in randomised trials: mandatory and mystical. Lancet (2005) 4.30
Electronic fetal monitoring as a public health screening program: the arithmetic of failure. Obstet Gynecol (2010) 2.89
Second-trimester abortion for fetal anomalies or fetal death: labor induction compared with dilation and evacuation. Obstet Gynecol (2011) 2.83
Sample size slippages in randomised trials: exclusions and the lost and wayward. Lancet (2002) 2.62
Epidemiologic research using administrative databases: garbage in, garbage out. Obstet Gynecol (2010) 2.50
Case-control studies: research in reverse. Lancet (2002) 2.38
Multiplicity in randomised trials II: subgroup and interim analyses. Lancet (2005) 2.34
Multiplicity in randomised trials I: endpoints and treatments. Lancet (2005) 2.32
Emergency contraception: politics trumps science at the U.S. Food and Drug Administration. Obstet Gynecol (2004) 2.14
Education for contraceptive use by women after childbirth. Cochrane Database Syst Rev (2012) 1.68
Hormonal contraceptives for contraception in overweight or obese women. Cochrane Database Syst Rev (2010) 1.61
Social desirability bias in family planning studies: a neglected problem. Contraception (2009) 1.50
Unequal group sizes in randomised trials: guarding against guessing. Lancet (2002) 1.45
Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev (2011) 1.44
Sex hormone-binding globulin: not a surrogate marker for venous thromboembolism in women using oral contraceptives. Contraception (2008) 1.43
Weighing the evidence--metaquality and immunologic problems in in vitro fertilization cycles? Fertil Steril (2005) 1.38
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. Hum Mol Genet (2011) 1.35
The gene for paroxysmal non-kinesigenic dyskinesia encodes an enzyme in a stress response pathway. Hum Mol Genet (2004) 1.29
Reducing publication bias through trial registration. Obstet Gynecol (2007) 1.27
Interventions for pain with intrauterine device insertion. Cochrane Database Syst Rev (2009) 1.24
Noncontraceptive health benefits of intrauterine devices: a systematic review. Obstet Gynecol Surv (2002) 1.17
Intrauterine devices for adolescents: a systematic review. Contraception (2009) 1.17
Advance provision of emergency contraception for pregnancy prevention: a meta-analysis. Obstet Gynecol (2007) 1.13
Routine follow-up visits after first-trimester induced abortion. Obstet Gynecol (2004) 1.12
Pitfalls of research linking the intrauterine device to pelvic inflammatory disease. Obstet Gynecol (2013) 1.05
Combined oral contraceptive pills for treatment of acne. Cochrane Database Syst Rev (2009) 1.04
Reducing publication bias of prospective clinical trials through trial registration. Contraception (2007) 1.03
Effective medical education: insights from the Cochrane Library. Obstet Gynecol Surv (2008) 1.03
Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev (2013) 1.02
Education for contraceptive use by women after childbirth. Cochrane Database Syst Rev (2010) 0.99
Theory-based strategies for improving contraceptive use: a systematic review. Contraception (2009) 0.97
Combination contraceptives: effects on weight. Cochrane Database Syst Rev (2014) 0.97
A Nurr1 point mutant, implicated in Parkinson's disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription. Neurobiol Dis (2007) 0.94
Clinical practice. A request for abortion. N Engl J Med (2011) 0.93
Combination contraceptives: effects on weight. Cochrane Database Syst Rev (2011) 0.93
Theory-based interventions for contraception. Cochrane Database Syst Rev (2013) 0.92
VAMP1 mutation causes dominant hereditary spastic ataxia in Newfoundland families. Am J Hum Genet (2012) 0.91
Skin patch and vaginal ring versus combined oral contraceptives for contraception. Cochrane Database Syst Rev (2013) 0.91
Nonhormonal drugs for contraception in men: a systematic review. Obstet Gynecol Surv (2005) 0.90
Combination contraceptives: effects on weight. Cochrane Database Syst Rev (2008) 0.89
20 µg versus >20 µg estrogen combined oral contraceptives for contraception. Cochrane Database Syst Rev (2013) 0.89
Continuous or extended cycle vs. cyclic use of combined hormonal contraceptives for contraception. Cochrane Database Syst Rev (2014) 0.88
Theory-based interventions for contraception. Cochrane Database Syst Rev (2011) 0.88
Refinement of the DYT15 locus in myoclonus dystonia. Mov Disord (2007) 0.88
Sino-implant (II)--a levonorgestrel-releasing two-rod implant: systematic review of the randomized controlled trials. Contraception (2009) 0.87
The Cochrane Fertility Regulation Group: synthesizing the best evidence about family planning. Contraception (2006) 0.87
Considerations regarding the etiology and future treatment of autosomal recessive versus idiopathic Parkinson disease. Curr Treat Options Neurol (2012) 0.87
Expectant care versus surgical treatment for miscarriage. Cochrane Database Syst Rev (2012) 0.87
Family planning for obese women: challenges and opportunities. Contraception (2005) 0.86
Effect of a levonorgestrel intrauterine system on women with type 1 diabetes: a randomized trial. Obstet Gynecol (2005) 0.85
Steroidal contraceptives: effect on bone fractures in women. Cochrane Database Syst Rev (2014) 0.85
Triphasic versus monophasic oral contraceptives for contraception. Cochrane Database Syst Rev (2011) 0.84
Expanding access to intrauterine contraception. Am J Obstet Gynecol (2009) 0.84
Strategies for communicating contraceptive effectiveness. Cochrane Database Syst Rev (2013) 0.84
Effect of lactation on maternal body weight: a systematic review. Obstet Gynecol Surv (2003) 0.83
Surrogate end points in women's health research: science, protoscience, and pseudoscience. Fertil Steril (2010) 0.83
20 µg versus >20 µg estrogen combined oral contraceptives for contraception. Cochrane Database Syst Rev (2011) 0.83
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus. Cochrane Database Syst Rev (2014) 0.83
Is there seasonal variation in risk of Parkinson's disease? Mov Disord (2007) 0.82
Combined oral contraceptive pills for treatment of acne. Cochrane Database Syst Rev (2012) 0.82
Twenty micrograms vs. >20 microg estrogen oral contraceptives for contraception: systematic review of randomized controlled trials. Contraception (2005) 0.82
Theory-based interventions for contraception. Cochrane Database Syst Rev (2009) 0.82
Hormonal contraceptives for contraception in overweight or obese women. Cochrane Database Syst Rev (2013) 0.82
Combination injectable contraceptives for contraception. Cochrane Database Syst Rev (2008) 0.82
Skin patch and vaginal ring versus combined oral contraceptives for contraception. Cochrane Database Syst Rev (2010) 0.80
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus. Cochrane Database Syst Rev (2009) 0.80
Postpartum education for contraception: a systematic review. Obstet Gynecol Surv (2010) 0.80
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus. Cochrane Database Syst Rev (2012) 0.79
Steroidal contraceptives: effect on bone fractures in women. Cochrane Database Syst Rev (2011) 0.79
Universal insurance coverage for contraceptives: a public health imperative. Contraception (2004) 0.79
The public health impact of legal abortion: 30 years later. Perspect Sex Reprod Health (2003) 0.78
Pain management for tubal sterilization by hysteroscopy. Cochrane Database Syst Rev (2012) 0.78
Steroidal contraceptives: effect on bone fractures in women. Cochrane Database Syst Rev (2009) 0.78
Combined oral contraceptive pills for treatment of acne. Cochrane Database Syst Rev (2012) 0.78
Large deletions account for an increasing number of mutations in SGCE. Mov Disord (2008) 0.77
20 microg versus >20 microg estrogen combined oral contraceptives for contraception. Cochrane Database Syst Rev (2008) 0.77
Removing the black box warning for depot medroxyprogesterone acetate. Contraception (2011) 0.77
Immediate start of hormonal contraceptives for contraception. Cochrane Database Syst Rev (2012) 0.77
Combination estrogen-progestin contraceptives and body weight: systematic review of randomized controlled trials. Obstet Gynecol (2004) 0.76
Parsing the potential of a new male contraceptive. Nat Med (2012) 0.75
Medical abortion for adolescents. BMJ (2011) 0.75
Politics, power, and procreation. MedGenMed (2005) 0.75
Risks of mifepristone abortion in context. Contraception (2006) 0.75
Start now or start something else? J Adolesc Health (2008) 0.75
Rates of birth defect(s) and exposure to IUD during pregnancy. Contraception (2004) 0.75
[Epidemiological methods 8: blinded randomized trial: what one covers up is what one obtains]. Z Arztl Fortbild Qualitatssich (2007) 0.75
[Failures in sample size calculation in randomized trial: mandatory and mystical]. Z Arztl Fortbild Qualitatssich (2006) 0.75
Hormonal and intrauterine methods for contraception for women aged 25 years and younger. Cochrane Database Syst Rev (2012) 0.75
Intrauterine insemination versus timed intercourse for cervical hostility in subfertile couples. Obstet Gynecol Surv (2006) 0.75
"Therapeutic" bed rest in pregnancy: unethical and unsupported by data. Obstet Gynecol (2013) 0.75
Get in the spirit with SPIRIT 2013: protocol content guideline for clinical trials. Contraception (2013) 0.75
Medical misspellings. Obstet Gynecol (2003) 0.75